Latest & greatest articles for tuberculosis

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Top results for tuberculosis

101. The mask of acute bacterial pneumonia may disguise the face of tuberculosis Full Text available with Trip Pro

The mask of acute bacterial pneumonia may disguise the face of tuberculosis Pulmonary tuberculosis (TB) can present as acute pneumonia. Differentiation of tuberculous from non-tuberculous community-acquired pneumonia (CAP) is an important challenge in endemic areas. The purpose of this study was the comparison between characteristics of tuberculous and non-tuberculous CAP patients.In this prospective and observational study, all adult patients (aged ≥16 years) who were admitted to Imam Reza

2017 Electronic physician

102. India's plan to eliminate tuberculosis by 2025: converting rhetoric into reality Full Text available with Trip Pro

India's plan to eliminate tuberculosis by 2025: converting rhetoric into reality 28589035 2018 11 13 2059-7908 2 2 2016 BMJ global health BMJ Glob Health India's plan to eliminate tuberculosis by 2025: converting rhetoric into reality. e000326 10.1136/bmjgh-2017-000326 Pai Madhukar M McGill Global Health Programs & McGill International TB Centre, McGill University, Montreal, Canada. Manipal McGill Centre for Infectious Diseases, Manipal University, Manipal, India. Bhaumik Soumyadeep S BMJ

2017 BMJ global health

103. The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognition Full Text available with Trip Pro

The bacillary and macrophage response to hypoxia in tuberculosis and the consequences for T cell antigen recognition Mycobacterium tuberculosis is a facultative anaerobe and its characteristic pathological hallmark, the granuloma, exhibits hypoxia in humans and in most experimental models. Thus the host and bacillary adaptation to hypoxia is of central importance in understanding pathogenesis and thereby to derive new drug treatments and vaccines.Copyright © 2016 The Author(s). Published

2017 Microbes and infection

104. Fumarase deficiency causes protein and metabolite succination and intoxicates Mycobacterium tuberculosis Full Text available with Trip Pro

Fumarase deficiency causes protein and metabolite succination and intoxicates Mycobacterium tuberculosis Enzymes of central carbon metabolism are essential mediators of Mycobacterium tuberculosis (Mtb) physiology and pathogenicity, but are often perceived to lack sufficient species selectivity to be pursued as potential drug targets. Fumarase (Fum) is an enzyme of the canonical tricarboxylic acid cycle and is dispensable in many organisms. Transposon mutagenesis studies in Mtb, however

2017 Cell chemical biology

105. Tuberculosis. (Abstract)

Tuberculosis. This issue provides a clinical overview of tuberculosis, focusing on screening, prevention, diagnosis, and treatment. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic in collaboration with the ACP's Medical Education and Publishing divisions and with the assistance

2017 Annals of Internal Medicine

106. Interventions to improve contact tracing for tuberculosis in specific groups and in wider populations: an evidence synthesis

Interventions to improve contact tracing for tuberculosis in specific groups and in wider populations: an evidence synthesis Interventions to improve contact tracing for tuberculosis in specific groups and in wider populations: an evidence synthesis Interventions to improve contact tracing for tuberculosis in specific groups and in wider populations: an evidence synthesis Baxter S, Goyder E, Chambers D, Johnson M, Preston L & Booth A. Record Status This is a bibliographic record of a published (...) health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Baxter S, Goyder E, Chambers D, Johnson M, Preston L & Booth A.. Interventions to improve contact tracing for tuberculosis in specific groups and in wider populations: an evidence synthesis. Health Services and Delivery Research 2017; 5(1) Authors' objectives The tracing and screening of people who have had contact with an active case of tuberculosis (TB

2017 Health Technology Assessment (HTA) Database.

107. Multiple large clusters of tuberculosis in London: a cross-sectional analysis of molecular and spatial data Full Text available with Trip Pro

Multiple large clusters of tuberculosis in London: a cross-sectional analysis of molecular and spatial data Large outbreaks of tuberculosis (TB) represent a particular threat to disease control because they reflect multiple instances of active transmission. The extent to which long chains of transmission contribute to high TB incidence in London is unknown. We aimed to estimate the contribution of large clusters to the burden of TB in London and identify risk factors. We identified TB patients

2017 ERJ open research

108. Who pays for cooperation in global health? A comparative analysis of WHO, the World Bank, the Global Fund to Fight HIV/AIDS, Tuberculosis and Malaria, and Gavi, the Vaccine Alliance. Full Text available with Trip Pro

Who pays for cooperation in global health? A comparative analysis of WHO, the World Bank, the Global Fund to Fight HIV/AIDS, Tuberculosis and Malaria, and Gavi, the Vaccine Alliance. In this report we assess who pays for cooperation in global health through an analysis of the financial flows of WHO, the World Bank, the Global Fund to Fight HIV/AIDS, TB and Malaria, and Gavi, the Vaccine Alliance. The past few decades have seen the consolidation of influence in the disproportionate roles the USA

2017 Lancet

109. Transmission of Extensively Drug-Resistant Tuberculosis in South Africa. Full Text available with Trip Pro

Transmission of Extensively Drug-Resistant Tuberculosis in South Africa. Drug-resistant tuberculosis threatens recent gains in the treatment of tuberculosis and human immunodeficiency virus (HIV) infection worldwide. A widespread epidemic of extensively drug-resistant (XDR) tuberculosis is occurring in South Africa, where cases have increased substantially since 2002. The factors driving this rapid increase have not been fully elucidated, but such knowledge is needed to guide public health (...) interventions.We conducted a prospective study involving 404 participants in KwaZulu-Natal Province, South Africa, with a diagnosis of XDR tuberculosis between 2011 and 2014. Interviews and medical-record reviews were used to elicit information on the participants' history of tuberculosis and HIV infection, hospitalizations, and social networks. Mycobacterium tuberculosis isolates underwent insertion sequence (IS)6110 restriction-fragment-length polymorphism analysis, targeted gene sequencing, and whole-genome

2017 NEJM

110. The impact of ISGylation during Mycobacterium tuberculosis infection in mice Full Text available with Trip Pro

The impact of ISGylation during Mycobacterium tuberculosis infection in mice Mycobacterium tuberculosis infection results in 1.5 million deaths annually. Type I interferon (IFN) signaling through its receptor IFNAR correlates with increased severity of disease, although how this increases susceptibility to M. tuberculosis remains uncertain. ISG15 is one of the most highly induced interferon stimulated genes (ISGs) during M. tuberculosis infection. ISG15 functions by conjugation to target (...) proteins (ISGylation), by noncovalent association with intracellular proteins, and by release from the cell. Recent studies indicated that ISG15 can function via conjugation-independent mechanisms to suppress the type I IFN response. These data raised the question of whether ISG15 may have diverse and sometimes opposing functions during M. tuberculosis infection. To address this, we analyzed ISGylation during M. tuberculosis infection and show that ISGylated proteins accumulate following infection

2017 Microbes and infection

111. Choroidal neovascularization secondary to tuberculosis: Presentation and management Full Text available with Trip Pro

Choroidal neovascularization secondary to tuberculosis: Presentation and management While there are many known etiologies of choroidal neovascularization (CNV), tuberculosis is not a well-known causative agent. In this case series, we highlight CNV occurring secondary to tuberculous chorioretinitis, its presentation, and its management.We retrospectively reviewed the charts and imaging of four patients who presented with presumed tuberculous chorioretinitis and CNV. Three of these patients had (...) signs of intraocular inflammation and were also found to have active macular CNV. The one remaining patient had chorioretinal scars from prior posterior uveitis and previously treated macular CNV membranes. The three patients with active disease were started on anti-tuberculosis medications and oral corticosteroids, and they also received intravitreal anti-vascular endothelial growth factor (VEGF) injections as needed for the CNV. There was a significant improvement in the clinical course of all

2017 American journal of ophthalmology case reports

112. Determining clinical decision thresholds for HIV-positive patients suspected of having tuberculosis

Determining clinical decision thresholds for HIV-positive patients suspected of having tuberculosis Determining clinical decision thresholds for HIV-positive patients suspected of having tuberculosis | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Determining clinical decision thresholds for HIV-positive patients suspected of having tuberculosis Article Text Original EBM Research Determining clinical decision thresholds for HIV

2017 Evidence-Based Medicine

113. Compendium of WHO guidelines and associated standards: ensuring optimum delivery of the cascade of care for patients with tuberculosis

Compendium of WHO guidelines and associated standards: ensuring optimum delivery of the cascade of care for patients with tuberculosis Sign in JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse My Account Statistics Related Links Sign in to IRIS E-Mail Address: Password: Sign in Register new user Register an account to subscribe to collections for email updates, and submit new items to IRIS. Sign in

2017 WHO

114. Handbook for the use of digital technologies to support tuberculosis medication adherence

Handbook for the use of digital technologies to support tuberculosis medication adherence Handbook for the use of digital technologies to support tuberculosis medication adherence JavaScript is disabled for your browser. Some features of this site may not work without it. Toggle navigation Toggle navigation Search Browse Statistics Related Links Handbook for the use of digital technologies to support tuberculosis medication adherence View/ Open Rights View Statistics Altmetrics Share Citation (...) World Health Organization . (‎2017)‎. Handbook for the use of digital technologies to support tuberculosis medication adherence. World Health Organization. . License: CC BY-NC-SA 3.0 IGO Description vi, 50 p. Gov't Doc # WHO/HTM/TB/2017.30 ISBN 9789241513456 Collections Language English Metadata Related items Showing items related by title and MeSH subject.  Organisation mondiale de la Santé (‎ WHO/HTM/TB/2014.1 , 2014 )‎  Всемирная организация здравоохранения (‎ WHO/FWC/WSH/17.05 , 2017

2017 WHO