Latest & greatest articles for tuberculosis

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Top results for tuberculosis

21. Post-migration follow-up programme for migrants at increased risk of developing tuberculosis: a cohort study

Post-migration follow-up programme for migrants at increased risk of developing tuberculosis: a cohort study 30018973 2018 11 14 2312-0541 4 3 2018 Jul ERJ open research ERJ Open Res Post-migration follow-up programme for migrants at increased risk of developing tuberculosis: a cohort study. 00008-2018 10.1183/23120541.00008-2018 Following pre-migration screening for tuberculosis (TB), migrants who are deemed to be at a high risk of developing TB must attend post-entry follow-up in Australia

ERJ open research2018 Full Text: Link to full Text with Trip Pro

22. Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination.

Prevention of M. tuberculosis Infection with H4:IC31 Vaccine or BCG Revaccination. BACKGROUND: Recent Mycobacterium tuberculosis infection confers a predisposition to the development of tuberculosis disease, the leading killer among global infectious diseases. H4:IC31, a candidate subunit vaccine, has shown protection against tuberculosis disease in preclinical models, and observational studies have indicated that primary bacille Calmette-Guérin (BCG) vaccination may offer partial protection (...) against infection. METHODS: In this phase 2 trial, we randomly assigned 990 adolescents in a high-risk setting who had undergone neonatal BCG vaccination to receive the H4:IC31 vaccine, BCG revaccination, or placebo. All the participants had negative results on testing for M. tuberculosis infection on the QuantiFERON-TB Gold In-tube assay (QFT) and for the human immunodeficiency virus. The primary outcomes were safety and acquisition of M. tuberculosis infection, as defined by initial conversion

NEJM2018 Full Text: Link to full Text with Trip Pro

23. Isoniazid-Rifapentine for Latent Tuberculosis Infection: A Systematic Review and Meta-analysis

Isoniazid-Rifapentine for Latent Tuberculosis Infection: A Systematic Review and Meta-analysis 29910114 2018 06 18 1873-2607 2018 Jun 11 American journal of preventive medicine Am J Prev Med Isoniazid-Rifapentine for Latent Tuberculosis Infection: A Systematic Review and Meta-analysis. S0749-3797(18)31737-9 10.1016/j.amepre.2018.04.030 Latent tuberculosis infection diagnosis and treatment is a strategic priority for eliminating tuberculosis in the U.S. The Centers for Disease Control (...) and Prevention has recommended the short-course regimen of 3-month isoniazid-rifapentine administered by directly observed therapy. However, longer-duration regimens remain the most widely prescribed latent tuberculosis infection treatments. Limitation on adoption of 3-month isoniazid-rifapentine in the U.S. might be because of patients' preference for self-administered therapy, providers' lack of familiarity with 3-month isoniazid-rifapentine, or lack of resources to support directly observed therapy

EvidenceUpdates2018

24. Epidemiology of multidrug-resistant tuberculosis (MDR-TB) in Ethiopia: a systematic review and meta-analysis of the prevalence, determinants and treatment outcome

Epidemiology of multidrug-resistant tuberculosis (MDR-TB) in Ethiopia: a systematic review and meta-analysis of the prevalence, determinants and treatment outcome 29942536 2018 11 14 2055-0936 4 2018 Tropical diseases, travel medicine and vaccines Trop Dis Travel Med Vaccines Epidemiology of multidrug-resistant tuberculosis (MDR-TB) in Ethiopia: a systematic review and meta-analysis of the prevalence, determinants and treatment outcome. 5 10.1186/s40794-018-0065-5 The emergence of MDR-TB (...) Misgun M 3Department of Public health, college of Medicine and Health Sciences, Arba Minch University, Arba Minch City, Ethiopia. grid.442844.a eng Journal Article Review 2018 06 14 England Trop Dis Travel Med Vaccines 101674442 2055-0936 Drug resistance MDR-TB Treatment outcome Tuberculosis TG: is Bsc/public health, MPH in Epidemiology and Biostatistics, Lecturer at Department of Public health, College of Medicine and Health Sciences, Wolkite University, Wolkite, Ethiopia.Not applicable.The authors

Tropical diseases, travel medicine and vaccines2018 Full Text: Link to full Text with Trip Pro

25. Rapid diagnosis of pulmonary tuberculosis by combined molecular and immunological methods

Rapid diagnosis of pulmonary tuberculosis by combined molecular and immunological methods 29599184 2018 05 04 1399-3003 51 5 2018 May The European respiratory journal Eur. Respir. J. Rapid diagnosis of pulmonary tuberculosis by combined molecular and immunological methods. 1702189 10.1183/13993003.02189-2017 Diagnosing pulmonary tuberculosis (TB) may be delayed until culture results become available.We ascertained the accuracy of a stepwise diagnostic algorithm for the rapid diagnosis (...) of pulmonary TB by GeneXpert from sputum and/or bronchoalveolar lavage (BAL) followed by a Mycobacterium tuberculosis- specific BAL ELISPOT assay in patients with a suspected diagnosis of pulmonary TB at a clinical referral centre in Germany.Among 166 patients with a presumptive diagnosis of pulmonary TB, 81 cases were confirmed by M. tuberculosis culture from sputum and/or BAL. In 66 out of 81 (81.5%) cases, patients initially had M. tuberculosis detected by GeneXpert from sputum; in addition, six out

EvidenceUpdates2018

26. Towards the elimination of paediatric tuberculosis in high-income, immigrant-receiving countries: a 25-year conventional and molecular epidemiological case study

Towards the elimination of paediatric tuberculosis in high-income, immigrant-receiving countries: a 25-year conventional and molecular epidemiological case study 29750144 2018 11 14 2312-0541 4 2 2018 Apr ERJ open research ERJ Open Res Towards the elimination of paediatric tuberculosis in high-income, immigrant-receiving countries: a 25-year conventional and molecular epidemiological case study. 00131-2017 10.1183/23120541.00131-2017 The epidemiology of tuberculosis (TB) in high-income (...) countries is increasingly dictated by immigration. The influence of this trend on paediatric TB and TB elimination are not well defined. We undertook a 25-year conventional and molecular epidemiologic study of paediatric TB in Alberta, one of four major immigrant-receiving provinces in Canada. All isolates of Mycobacterium tuberculosis were DNA fingerprinted using standard methodology. Between 1990 and 2014, 176 children aged 0-14 years were diagnosed with TB. Foreign-born children or Canadian-born

ERJ open research2018 Full Text: Link to full Text with Trip Pro

27. F-18 Fluorodeoxyglucose Positron Emission Tomography/ Computed Tomography Findings of Isolated Gastric Tuberculosis mimicking Gastric Cancer and Lymphoma

F-18 Fluorodeoxyglucose Positron Emission Tomography/ Computed Tomography Findings of Isolated Gastric Tuberculosis mimicking Gastric Cancer and Lymphoma 29963474 2018 11 14 2231-5047 8 1 2018 Jan-Jun Euroasian journal of hepato-gastroenterology Euroasian J Hepatogastroenterol F-18 Fluorodeoxyglucose Positron Emission Tomography/ Computed Tomography Findings of Isolated Gastric Tuberculosis mimicking Gastric Cancer and Lymphoma. 93-96 10.5005/jp-journals-10018-1270 Tuberculosis (TB) infection (...) to our knowledge, this is the first report about F-18 FDG PET/CT findings in the diagnosis of isolated gastric TB. F-18 FDG PET/CT may provide help in the diagnosis and follow-up of isolated gastric TB in challenging cases. How to cite this article: Akdogan RA, Rakici H, Güngör S, Bedir R, Akdogan E. F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography Findings of Isolated Gastric Tuberculosis mimicking Gastric Cancer and Lymphoma. Euroasian J Hepato-Gastroenterol 2018;8(1):93-96

Euroasian journal of hepato-gastroenterology2018 Full Text: Link to full Text with Trip Pro

28. Predicting pulmonary tuberculosis in immigrants: a retrospective cohort study

Predicting pulmonary tuberculosis in immigrants: a retrospective cohort study 29692996 2018 11 14 2312-0541 4 2 2018 Apr ERJ open research ERJ Open Res Predicting pulmonary tuberculosis in immigrants: a retrospective cohort study. 00170-2017 10.1183/23120541.00170-2017 Our objective was to investigate whether pulmonary tuberculosis (PTB) can be predicted from features of a targeted medical history and basic laboratory investigations in immigrants. A retrospective cohort of 391 foreign-born (...) adults referred to the Edmonton Tuberculosis Clinic (Edmonton, AB, Canada) was studied using multiple logistic regression analysis to predict PTB. Seven characteristics of disease were used as explanatory variables. Cross-validation assessed performance. Each predictor was tested on two outcomes: "culture-positive" and "smear-positive". Receiver operating characteristic (ROC) curves were generated and the area under the ROC curve (AUC) was quantified. Symptoms, subacute duration of symptoms, risk

ERJ open research2018 Full Text: Link to full Text with Trip Pro

29. Risk of tuberculosis transmission among healthcare workers

Risk of tuberculosis transmission among healthcare workers 29637080 2018 11 14 2312-0541 4 2 2018 Apr ERJ open research ERJ Open Res Risk of tuberculosis transmission among healthcare workers. 00161-2017 10.1183/23120541.00161-2017 Data from a prospective molecular-epidemiological study (1997-2015) of patients with culture-confirmed tuberculosis in Hamburg, Germany, were evaluated to assess the occupational risk of Mycobacterium tuberculosis complex transmission in a low-incidence setting (...) . Isolates of M. tuberculosis complex were genotyped using IS6110 restriction fragment length polymorphism analysis. Results of structured questionnaires, geographical mapping and additional patient interviews were used for confirming epidemiological links. Out of the 2393 cases, 918 (38.4%) were classified into 224 clusters comprising 2-70 patients per cluster. Among the 918 cluster members, epidemiological links could be confirmed in 340 (37.0%) patients. In total, 55 (2.3%) patients were healthcare

ERJ open research2018 Full Text: Link to full Text with Trip Pro

30. Rapid tests for diagnosing drug resistant tuberculosis are accurate and may be cost effective

Rapid tests for diagnosing drug resistant tuberculosis are accurate and may be cost effective NIHR DC | Signal - Rapid tests for diagnosing drug resistant tuberculosis are accurate and may be cost effective Dissemination Centre Discover Portal NIHR DC Discover NIHR Signal Rapid tests for diagnosing drug resistant tuberculosis are accurate and may be cost effective Published on 9 November 2015 This NIHR funded systematic review and economic evaluation found that three rapid tests for diagnosing (...) drug resistant tuberculosis were highly accurate and likely to be cost effective in the UK. These tests produce results within one day of obtaining a sample. This is a significant reduction compared with the standard tests which can take about six weeks or even longer to grow the bacteria. Adding rapid testing to current diagnostic pathways could speed up access to the best treatment and shorten the time people without the disease are kept in isolation as a precaution. This could save money, reduce

NIHR Dissemination Centre2018

31. Daily vs Intermittent Antituberculosis Therapy for Pulmonary Tuberculosis in Patients With HIV: A Randomized Clinical Trial

Daily vs Intermittent Antituberculosis Therapy for Pulmonary Tuberculosis in Patients With HIV: A Randomized Clinical Trial 29507938 2018 04 19 2168-6114 178 4 2018 Apr 01 JAMA internal medicine JAMA Intern Med Daily vs Intermittent Antituberculosis Therapy for Pulmonary Tuberculosis in Patients With HIV: A Randomized Clinical Trial. 485-493 10.1001/jamainternmed.2018.0141 The benefit of daily over thrice-weekly antituberculosis therapy among HIV-positive patients with pulmonary tuberculosis (...) (TB) who are receiving antiretroviral therapy remains unproven. To compare the efficacy and safety of daily, part-daily, and intermittent antituberculosis therapy regimens in the treatment of HIV-associated pulmonary TB. This open-label, randomized clinical trial was conducted by the National Institute for Research in Tuberculosis, south India. Adults infected with HIV with newly diagnosed, culture-positive, pulmonary TB were enrolled between September 14, 2009, and January 18, 2016. Patients were

EvidenceUpdates2018

32. The impact of digital health technologies on tuberculosis treatment: a systematic review

The impact of digital health technologies on tuberculosis treatment: a systematic review 29326332 2018 04 14 1399-3003 51 1 2018 Jan The European respiratory journal Eur. Respir. J. The impact of digital health technologies on tuberculosis treatment: a systematic review. 1701596 10.1183/13993003.01596-2017 Digital technologies are increasingly harnessed to support treatment of persons with tuberculosis (TB). Since in-person directly observed treatment (DOT) can be resource intensive (...) , and McGill International Tuberculosis Centre, Montreal, Canada. Both authors contributed equally. Oxlade Olivia O Montreal Chest Institute, Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre, and McGill International Tuberculosis Centre, Montreal, Canada. Mappin-Kasirer Benjamin B Montreal Chest Institute, Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre, and McGill International

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

33. Discovery of a unique Mycobacterium tuberculosis protein through proteomic analysis of urine from patients with active tuberculosis

Discovery of a unique Mycobacterium tuberculosis protein through proteomic analysis of urine from patients with active tuberculosis Redirecting

Microbes and infection2018 Full Text: Link to full Text with Trip Pro

34. Peritoneal Tuberculosis After Robot-Assisted Laparoscopic Prostatectomy with Extended Lymph Node Dissection

Peritoneal Tuberculosis After Robot-Assisted Laparoscopic Prostatectomy with Extended Lymph Node Dissection 29675476 2018 11 14 2379-9889 4 1 2018 Journal of endourology case reports J Endourol Case Rep Peritoneal Tuberculosis After Robot-Assisted Laparoscopic Prostatectomy with Extended Lymph Node Dissection. 48-50 10.1089/cren.2018.0018 Background: Peritoneal tuberculosis (TB) is a relatively uncommon presentation of extrapulmonary TB. Early diagnosis of peritoneal TB is difficult because (...) with fever and abdominal distension. Ultrasonography and computed tomography (CT) revealed massive abdominal ascites. Ascites sample was cloudy, with increased white blood cells and normal creatinine level. No anastomotic leak was found. Bacterial infection of a lymphocele was considered, and cefmetazole 2 g/day for 3 days was prescribed. Despite antibacterial therapy, fever persisted. Polymerase chain reaction testing of ascitic fluid was positive for Mycobacterium tuberculosis . The patient

Journal of endourology case reports2018 Full Text: Link to full Text with Trip Pro

35. Physicians' perspectives on communication and decision making in clinical encounters for treatment of latent tuberculosis infection

Physicians' perspectives on communication and decision making in clinical encounters for treatment of latent tuberculosis infection Physicians' perspectives on communication and decision making in clinical encounters for treatment of latent tuberculosis infection | European Respiratory Society Main menu User menu Search Search for this keyword Search for this keyword Physicians' perspectives on communication and decision making in clinical encounters for treatment of latent tuberculosis (...) infection Claudia C. Dobler , Sinthia Bosnic-Anticevich , Carol L. Armour ERJ Open Research 2018 4: 00146-2017; DOI: 10.1183/23120541.00146-2017 Claudia C. Dobler Liverpool Hospital, South Western Sydney Clinical School, University of New South Wales, Sydney, Australia Ingham Institute of Applied Medical Research, Sydney, Australia Woolcock Institute of Medical Research, University of Sydney, Sydney, Australia Centre of Research Excellence in Tuberculosis, University of Sydney, Sydney, Australia Mayo

ERJ open research2018 Full Text: Link to full Text with Trip Pro

36. Potential Application of Digitally Linked Tuberculosis Diagnostics for Real-Time Surveillance of Drug-Resistant Tuberculosis Transmission: Validation and Analysis of Test Results

Potential Application of Digitally Linked Tuberculosis Diagnostics for Real-Time Surveillance of Drug-Resistant Tuberculosis Transmission: Validation and Analysis of Test Results JMI-Potential Application of Digitally Linked Tuberculosis Diagnostics for Real-Time Surveillance of Drug-Resistant Tuberculosis Transmission: Validation and Analysis of Test Results | Ng | JMIR Medical Informatics Sorry, you need to enable javascript for this page to function properly. Menu Search User Sign Up Follow (...) surrogate marker for MDR-TB, as most rifampicin-resistant strains are also resistant to isoniazid [ - ]. Rifampicin resistance-conferring mutations are primarily situated at codon positions 426 to 452 [ ] within the 81-bp rifampicin resistance–determining region (RRDR) of the Mycobacterium tuberculosis RNA polymerase β subunit ( rpoB ) gene [ - ]. Consequently, commercially available molecular tests developed for rapid detection of MDR-TB only capture mutations in the RRDR, with or without mutations

JMIR medical informatics2018 Full Text: Link to full Text with Trip Pro

37. OMNIgene.SPUTUM suppresses contaminants while maintaining Mycobacterium tuberculosis viability and obviates cold-chain transport

OMNIgene.SPUTUM suppresses contaminants while maintaining Mycobacterium tuberculosis viability and obviates cold-chain transport OMNIgene.SPUTUM suppresses contaminants while maintaining Mycobacterium tuberculosis viability and obviates cold-chain transport Khalide Azam 1 , Nureisha Cadir 2 , Carla Madeira 1 , Stephen H. Gillespie 3 and Wilber Sabiiti 3 Affiliations: 1 Instituto Nacional de Saúde National Tuberculosis Reference Laboratory, Maputo, Mozambique. 2 FHI360 Challenge TB, Maputo (...) , Mozambique. 3 University of St Andrews School of Medicine, St Andrews, UK. Correspondence: Wilber Sabiiti, University of St Andrews School of Medicine, North Haugh, St Andrews KY16 9TF, UK. E-mail: ws31@st-andrews.ac.uk ABSTRACT Tuberculosis (TB) diagnostics are centralised, requiring long-distance transportation of specimens in most resource-limited settings. We evaluated the ability of OMNIgene.SPUTUM (OM-S) to obviate cold-chain transport of TB specimens. A two-arm (same-day and after 5days sample

ERJ open research2018 Full Text: Link to full Text with Trip Pro

38. Longitudinal analysis of HIV risk behaviour patterns and their predictors among public primary care patients with tuberculosis in South Africa

Longitudinal analysis of HIV risk behaviour patterns and their predictors among public primary care patients with tuberculosis in South Africa | * Number of Attempts: 0 /5 Browse journals by subject Information for Open access Help and info Connect with Taylor & Francis Copyright © 2018 Informa UK Limited Registered in England & Wales No. 3099067 5 Howick Place | London | SW1P 1WG We use cookies to improve your website experience. To learn about our use of cookies and how you can manage your

SAHARA J : journal of Social Aspects of HIV/AIDS Research Alliance2018 Full Text: Link to full Text with Trip Pro

39. Leveraging tuberculosis case relative locations to enhance case detection and linkage to care in Swaziland

Leveraging tuberculosis case relative locations to enhance case detection and linkage to care in Swaziland SHORT REPORT Open Access Leveraging tuberculosis case relative locations to enhance case detection and linkage to care in Swaziland Marie Brunetti 1† , Sathyanath Rajasekharan 1† , Piluca Ustero 2 , Katherine Ngo 2 , Welile Sikhondze 3 , Buli Mzileni 4 , Anna Mandalakas 2 and Alexander W. Kay 2* Abstract Background: In Swaziland, as in many high HIV/TB burden settings (...) demands novel analytic approaches to study TB case locations. We demonstrated the feasibility of linking relative locations to more precise geographical areas, enabling data-driven guidance for National Tuberculosis Programs’ resource allocation. In collaboration with the Swazi National Tuberculosis Control Program, this analysis highlighted opportunities to better align the active case finding national strategy with the TB disease burden. Keywords: Mapping, Geospatial, Relative location, Active case

Global health research and policy2018 Full Text: Link to full Text with Trip Pro

40. Time to change the single-centre approach to management of patients with tuberculosis: a novel network platform with automatic data import and data sharing

Time to change the single-centre approach to management of patients with tuberculosis: a novel network platform with automatic data import and data sharing Time to change the single-centre approach to management of patients with tuberculosis: a novel network platform with automatic data import and data sharing To the Editor: Ending the global tuberculosis (TB) epidemic by the year 2035 is one of the most ambitious goals of the World Health Organization (WHO). The WHO strategy is based on three (...) about the HIV immune–virological status, treatment, etc., can be automatically loaded from the already-running online Ligurian HIV Network, a similar regional online @ERSpublications Time to change the single-centre approach to TB http://ow.ly/lCeM30hBcbB Cite this article as: Riccardi N, Giannini B, Borghesi ML, et al. Time to change the single-centre approach to management of patients with tuberculosis: a novel network platform with automatic data import and data sharing. ERJ Open Res 2018; 4

ERJ open research2018 Full Text: Link to full Text with Trip Pro