Latest & greatest articles for traumatic brain injury

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Top results for traumatic brain injury

121. Predictors of extended rehabilitation length of stay after traumatic brain injury

Predictors of extended rehabilitation length of stay after traumatic brain injury 20875505 2010 09 29 2010 10 19 2010 09 29 1532-821X 91 10 2010 Oct Archives of physical medicine and rehabilitation Arch Phys Med Rehabil Predictors of extended rehabilitation length of stay after traumatic brain injury. 1495-504 10.1016/j.apmr.2010.07.010 To develop a prediction rule for acutely identifying patients at risk for extended rehabilitation length of stay (LOS) after traumatic brain injury (TBI (...) ) by using demographic and injury characteristics. Retrospective cohort study. Traumatic Brain Injury Model Systems. Sample of TBI survivors (N=7284) with injuries occurring between 1999 and 2009. Not applicable. Extended rehabilitation LOS defined as 67 days or longer. A multivariable model was built containing FIM motor and cognitive scores at admission, preinjury level of education, cause of injury, punctate/petechial hemorrhage, acute-care LOS, and primary payor source. The model had good calibration

EvidenceUpdates2010

122. Therapeutic hypothermia for paediatric traumatic brain injury

Therapeutic hypothermia for paediatric traumatic brain injury BestBets: Therapeutic hypothermia for paediatric traumatic brain injury within 8 hr Therapeutic hypothermia for paediatric traumatic brain injury within 8 hr Report By: Gabriel Cade - Emergency Medicine Physician Search checked by Venkatesh Gattu - Senior Emergency Medicine Trainee Institution: Baystate Medical Center aSpringfield, MA 01199, USA nd Manchester Royal Infirmary, Manchester, UK Date Submitted: 12th December 2009 Date (...) Completed: 9th July 2010 Last Modified: 9th July 2010 Status: Green (complete) Three Part Question In [paediatric patients presenting within 8 h of traumatic brain injury (TBI)] are [therapeutic hypothermia regimens better than normothermic care] in [improving patient survival]? Clinical Scenario An 8-year old child presents to the Emergency Department within six hours of an unclear incident at home which left nonspecific bruising and acute change in mental status. Fundoscopic exam reveals retinal

BestBETS2010

123. Intensive insulin therapy in severe traumatic brain injury: a randomized trial

Intensive insulin therapy in severe traumatic brain injury: a randomized trial 20032790 2010 04 13 2010 05 06 2011 11 17 1529-8809 68 4 2010 Apr The Journal of trauma J Trauma Intensive insulin therapy in severe traumatic brain injury: a randomized trial. 904-11 10.1097/TA.0b013e3181c9afc2 Intensive insulin therapy (IIT) has been shown to reduce morbidity and mortality in critically ill patients. Little investigation has been done to find out whether it improves the prognosis of patients (...) with severe traumatic brain injury (STBI). We conducted a prospective controlled study where adult patients with blunt STBI, with Glasgow Coma Scale

EvidenceUpdates2010

124. Rates of major depressive disorder and clinical outcomes following traumatic brain injury.

Rates of major depressive disorder and clinical outcomes following traumatic brain injury. CONTEXT: Uncertainties exist about the rates, predictors, and outcomes of major depressive disorder (MDD) among individuals with traumatic brain injury (TBI). OBJECTIVE: To describe MDD-related rates, predictors, outcomes, and treatment during the first year after TBI. DESIGN: Cohort from June 2001 through March 2005 followed up by structured telephone interviews at months 1 through 6, 8, 10, and 12 (data (...) once in the follow-up period. Point prevalences ranged between 31% at 1 month and 21% at 6 months. In a multivariate model, risk of MDD after TBI was associated with MDD at the time of injury (risk ratio [RR], 1.62; 95% confidence interval [CI], 1.37-1.91), history of MDD prior to injury (but not at the time of injury) (RR, 1.54; 95% CI, 1.31-1.82), age (RR, 0.61; 95% CI, 0.44-0.83 for > or = 60 years vs 18-29 years), and lifetime alcohol dependence (RR, 1.34; 95% CI, 1.14-1.57). Those with MDD

JAMA2010 Full Text: Link to full Text with Trip Pro

125. Is albumin use SAFE in patients with traumatic brain injury?

Is albumin use SAFE in patients with traumatic brain injury? Is albumin use SAFE in patients with traumatic brain injury? | Critical Care | Full Text Advertisement Search BioMed Central articles Search Impact Factor 4.950 Main menu Journal club critique Open Access Is albumin use SAFE in patients with traumatic brain injury? Christopher R Brackney , Luis A Diaz , Eric B Milbrandt , Ali Al-Khafaji and Joseph M Darby Critical Care 2010 14 :307 DOI: 10.1186/cc8940 © BioMed Central Ltd 2010 (...) Published: 9 April 2010 Article details Evidence-Based Medicine Journal Club Edited by: Eric B Milbrandt. University of Pittsburgh Department of Critical Care Medicine Expanded Abstract Citation Myburgh J, Cooper DJ, Finfer S, Bellomo R, Norton R, Bishop N, Kai LS, Vallance S: Saline or albumin for fluid resuscitation in patients with traumatic brain injury. N Engl J Med 2007, 357:874-884 [ ]. Background The Saline versus Albumin Fluid Evaluation study suggested that patients with traumatic brain injury

Critical Care - EBM Journal Club2010 Full Text: Link to full Text with Trip Pro

126. Haemostatic drugs for traumatic brain injury.

Haemostatic drugs for traumatic brain injury. BACKGROUND: Traumatic brain injury (TBI) is a leading cause of death and disability. Intracranial bleeding is a common complication of TBI, and intracranial bleeding can develop or worsen after hospital admission. Haemostatic drugs may reduce the occurrence or size of intracranial bleeds and consequently lower the morbidity and mortality associated with TBI. OBJECTIVES: To assess the effects of haemostatic drugs on mortality, disability (...) and thrombotic complications in patients with traumatic brain injury. SEARCH STRATEGY: We searched the electronic databases: Cochrane Injuries Group Specialised Register (3 February 2009), CENTRAL (The Cochrane Library 2009, Issue 1), MEDLINE (1950 to Week 3 2009), PubMed (searched 3 February 2009 (last 180 days)), EMBASE (1980 to Week 4 2009), CINAHL (1982 to January 2009), ISI Web of Science: Science Citation Index Expanded (SCI-EXPANDED) (1970 to January 2009), ISI Web of Science: Conference Proceedings

Cochrane2010

127. Prophylactic hypothermia for traumatic brain injury: a quantitative systematic review

Prophylactic hypothermia for traumatic brain injury: a quantitative systematic review Prophylactic hypothermia for traumatic brain injury: a quantitative systematic review Prophylactic hypothermia for traumatic brain injury: a quantitative systematic review Fox JL, Vu EN, Doyle-Waters M, Brubacher JR, Abu-Laban R, Hu Z CRD summary The review found that early prophylactic mild to moderate hypothermia improved mortality and functional outcomes after severe traumatic brain injury, especially when (...) a long-term or goal-directed cooling strategy was used. In view of limitations in the review, including poor quality studies and possible publication bias (both acknowledged by the authors), some caution may be required in interpreting the findings. Authors' objectives To evaluate the use of prophylactic hypothermia for traumatic brain injury. Searching MEDLINE, EMBASE, Web of Science, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Reviews, PapersFirst

DARE.2010

128. Hyperbaric oxygen therapy for traumatic brain injury (TBI) and post traumatic stress disorder (PTSD)

Hyperbaric oxygen therapy for traumatic brain injury (TBI) and post traumatic stress disorder (PTSD) Hyperbaric oxygen therapy for traumatic brain injury (TBI) and post traumatic stress disorder (PTSD) Hyperbaric oxygen therapy for traumatic brain injury (TBI) and post traumatic stress disorder (PTSD) Adams E Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA (...) database. Citation Adams E. Hyperbaric oxygen therapy for traumatic brain injury (TBI) and post traumatic stress disorder (PTSD) Boston: VA Technology Assessment Program (VATAP). 2010 Authors' conclusions Conclusions: Traumatic brain injury. The systematic reviews by McDonagh (2003) and Bennett (2004) provide the most rigorous and current information on the status of the clinical research for the use of HBO2 in TBI. Subsequent reviews identified these two reviews as the primary basis

Health Technology Assessment (HTA) Database.2010

129. Cost-effectiveness analysis of intravenous levetiracetam versus intravenous phenytoin for early onset seizure prophylaxis after neurosurgery and traumatic brain injury

Cost-effectiveness analysis of intravenous levetiracetam versus intravenous phenytoin for early onset seizure prophylaxis after neurosurgery and traumatic brain injury Cost-effectiveness analysis of intravenous levetiracetam versus intravenous phenytoin for early onset seizure prophylaxis after neurosurgery and traumatic brain injury Cost-effectiveness analysis of intravenous levetiracetam versus intravenous phenytoin for early onset seizure prophylaxis after neurosurgery and traumatic brain (...) after neurosurgery or traumatic brain injury, in the intensive care unit setting. The authors concluded that, from the perspective of the hospital, levetiracetam could be cost-effective compared with phenytoin. The methods were valid and the study was generally well presented. The authors’ conclusions seem robust. Type of economic evaluation Cost-effectiveness analysis Study objective This study examined the cost-effectiveness of intravenous levetiracetam, compared with conventional intravenous

NHS Economic Evaluation Database.2010

130. The Cognitive Effects of Mild Traumatic Brain Injury and Resulting Postconcussion Syndrome in High Risk Patients

The Cognitive Effects of Mild Traumatic Brain Injury and Resulting Postconcussion Syndrome in High Risk Patients "The Cognitive Effects of Mild Traumatic Brain Injury and Resulting Pos" by Terrance Hartmann < > > > > > Title Author Date of Award 8-14-2010 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Dr. Mark Pedemonte, MD Second Advisor Annjanette Sommers MS, PAC Third Advisor Rob Rosenow PharmD, OD Rights . Abstract Background: Mild (...) traumatic brain injury with postconcussion syndromes may be correlated with long term cognitive deficits. While 1.7 million traumatic brain injuries are reported each year, this number does not account for the many mild traumatic brain injuries that are not reported each year. Methods: Exhaustive search of available medical literature using the search engines: OVID, CINAHL, Entrez, and UpToDate. Keywords used were Mild Traumatic Brain Injury, Cognitive Disorders, Psychological Disorders, Neurological

Pacific University EBM Capstone Project2010

131. Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial.

Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial. 20924011 2010 10 06 2010 10 08 2016 12 15 1538-3598 304 13 2010 Oct 06 JAMA JAMA Out-of-hospital hypertonic resuscitation following severe traumatic brain injury: a randomized controlled trial. 1455-64 10.1001/jama.2010.1405 Hypertonic fluids restore cerebral perfusion with reduced cerebral edema and modulate inflammatory response to reduce subsequent neuronal injury and thus have (...) potential benefit in resuscitation of patients with traumatic brain injury (TBI). To determine whether out-of-hospital administration of hypertonic fluids improves neurologic outcome following severe TBI. Multicenter, double-blind, randomized, placebo-controlled clinical trial involving 114 North American emergency medical services agencies within the Resuscitation Outcomes Consortium, conducted between May 2006 and May 2009 among patients 15 years or older with blunt trauma and a prehospital Glasgow

JAMA2010 Full Text: Link to full Text with Trip Pro

132. Nursing management of adults with severe traumatic brain injury.

Nursing management of adults with severe traumatic brain injury. Nursing management of adults with severe traumatic brain injury. | National Guideline Clearinghouse Search Sign In Username or Email * Password * Remember Me Don't have an account? Guideline Summary NGC:006948 This guideline summary has been withdrawn from NGC. Please update your bookmarks. View all withdrawn summaries in the . About NGC Guideline Summaries NGC's guidelines summaries contain information systematically derived from

American Association of Neuroscience Nurses2009

133. Brain tissue oxygen and outcome after severe traumatic brain injury: a systematic review

Brain tissue oxygen and outcome after severe traumatic brain injury: a systematic review 19384213 2009 05 18 2009 06 08 2013 11 21 1530-0293 37 6 2009 Jun Critical care medicine Crit. Care Med. Brain tissue oxygen and outcome after severe traumatic brain injury: a systematic review. 2057-63 10.1097/CCM.0b013e3181a009f8 In this study, available medical literature were reviewed to determine whether brain hypoxia as measured by brain tissue oxygen (Bto2) levels is associated with increased risk (...) of poor outcome after traumatic brain injury (TBI). A secondary objective was to examine the safety profile of a direct BtO2 probe. DATA SOURCE AND EXTRACTION: Clinical studies published between 1993 and 2008 were identified from electronic databases, Index Medicus, bibliographies of pertinent articles, and expert consultation. The following inclusion criteria were applied for outcome analysis: 1) more than 10 patients described, 2) use of a direct Bto2 monitor, 3) brain hypoxia defined as Bto2 <10 mm

EvidenceUpdates2009

134. Interventions for apathy after traumatic brain injury.

Interventions for apathy after traumatic brain injury. BACKGROUND: Apathy is a deficiency in overt behavioural, emotional and cognitive components of goal-directed behaviour. It is a common occurrence after traumatic brain injury (TBI), with widespread impact. We have systematically reviewed studies examining the effectiveness of interventions for apathy in the TBI population. OBJECTIVES: To investigate the effectiveness of interventions for apathy in adults who have sustained a TBI (...) . This was evaluated by changes in behavioural, cognitive and emotional measures of apathy. SEARCH STRATEGY: We searched the following databases up to January 2008: CENTRAL (The Cochrane Library 2008, Issue 1), Database of Abstracts of Reviews of Effects, ACP Journal Club, MEDLINE (1950 to Jan 2008), EMBASE (1980 to Jan 2008), PsycINFO (1806 to Jan 2008), CINAHL (1982 Jan 2008), PsycBITE, AMED (1985 to Jan 2008), www.controlled-trials.com, www.clinicaltrials.gov and www.actr.org.au.The Cochrane Injuries Group's

Cochrane2009

135. Longitudinal trajectories of postconcussive symptoms in children with mild traumatic brain injuries and their relationship to acute clinical status

Longitudinal trajectories of postconcussive symptoms in children with mild traumatic brain injuries and their relationship to acute clinical status 19254996 2009 03 03 2009 03 30 2017 02 20 1098-4275 123 3 2009 Mar Pediatrics Pediatrics Longitudinal trajectories of postconcussive symptoms in children with mild traumatic brain injuries and their relationship to acute clinical status. 735-43 10.1542/peds.2008-1056 We examined whether mild traumatic brain injuries in children and adolescents (...) , especially when associated with acute clinical features reflecting more severe injury, result in different postinjury trajectories of postconcussive symptoms compared with mild orthopedic injuries. Participants in this prospective and longitudinal cohort study were 8- to 15-year-old children, 186 with mild traumatic brain injuries and 99 with mild orthopedic injuries, who were recruited from consecutive admissions to emergency departments in 2 large children's hospitals. Parents rated current

EvidenceUpdates2009 Full Text: Link to full Text with Trip Pro

136. A critical comparison of clinical decision instruments for computed tomographic scanning in mild closed traumatic brain injury in adolescents and adults

A critical comparison of clinical decision instruments for computed tomographic scanning in mild closed traumatic brain injury in adolescents and adults 18339447 2009 01 26 2009 02 10 2016 11 24 1097-6760 53 2 2009 Feb Annals of emergency medicine Ann Emerg Med A critical comparison of clinical decision instruments for computed tomographic scanning in mild closed traumatic brain injury in adolescents and adults. 180-8 10.1016/j.annemergmed.2008.01.002 A number of clinical decision aids have (...) been introduced to limit unnecessary computed tomographic scans in patients with mild traumatic brain injury. These aids differ in the risk factors they use to recommend a scan. We compare the instruments according to their sensitivity and specificity and recommend ones based on incremental benefit of correctly classifying patients as having surgical, nonsurgical, or no intracranial lesions. We performed a secondary analysis of prospectively collected database from 7,955 patients aged 10 years

EvidenceUpdates2009

137. Long-term risk of epilepsy after traumatic brain injury in children and young adults: a population-based cohort study.

Long-term risk of epilepsy after traumatic brain injury in children and young adults: a population-based cohort study. BACKGROUND: The risk of epilepsy shortly after traumatic brain injury is high, but how long this high risk lasts is unknown. We aimed to assess the risk of epilepsy up to 10 years or longer after traumatic brain injury, taking into account sex, age, severity, and family history. METHODS: We identified 1 605 216 people born in Denmark (1977-2002) from the Civil Registration (...) System. We obtained information on traumatic brain injury and epilepsy from the National Hospital Register and estimated relative risks (RR) with Poisson analyses. FINDINGS: Risk of epilepsy was increased after a mild brain injury (RR 2.22, 95% CI 2.07-2.38), severe brain injury (7.40, 6.16-8.89), and skull fracture (2.17, 1.73-2.71). The risk was increased more than 10 years after mild brain injury (1.51, 1.24-1.85), severe brain injury (4.29, 2.04-9.00), and skull fracture (2.06, 1.37-3.11). RR

Lancet2009

138. Hypothermia Therapy after Traumatic Brain Injury in Children

Hypothermia Therapy after Traumatic Brain Injury in Children PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2009

139. The economic impact of S-100B as a pre-head CT screening test on emergency department management of adult patients with mild traumatic brain injury

The economic impact of S-100B as a pre-head CT screening test on emergency department management of adult patients with mild traumatic brain injury The economic impact of S-100B as a pre-head CT screening test on emergency department management of adult patients with mild traumatic brain injury The economic impact of S-100B as a pre-head CT screening test on emergency department management of adult patients with mild traumatic brain injury Ruan S, Noyes K, Bazarian JJ Record Status (...) This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study estimated the cost reduction associated with serum-100B testing to determine whether a computed tomography (CT) scan was required for adults with an isolated mild traumatic brain injury. The authors

NHS Economic Evaluation Database.2009

140. Systematic review of the literature on pain in patients with polytrauma including traumatic brain injury

Systematic review of the literature on pain in patients with polytrauma including traumatic brain injury Systematic review of the literature on pain in patients with polytrauma including traumatic brain injury Systematic review of the literature on pain in patients with polytrauma including traumatic brain injury Dobscha SK, Clark ME, Morasco BJ, Freeman M, Campbell R, Helfand M CRD summary This review evaluated the assessment and management of pain in patients with polytraumatic injuries (...) , including traumatic brain injury and blast-related headache. The authors concluded that there was little evidence to guide pain assessment and treatment approaches. This conclusion reflects the evidence presented, but a cautious interpretation of reliability might be necessary due to potential biases in the review process. Authors' objectives To evaluate the assessment and management of pain in patients with polytraumatic injuries, including traumatic brain injury and blast-related headache. The review

DARE.2009