Latest & greatest articles for traumatic brain injury

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Top results for traumatic brain injury

101. Study protocol - A systematic review and meta-analysis of hypothermia in experimental traumatic brain injury: Why have promising animal studies not been replicated in pragmatic clinical trials? (PubMed)

Study protocol - A systematic review and meta-analysis of hypothermia in experimental traumatic brain injury: Why have promising animal studies not been replicated in pragmatic clinical trials? Traumatic brain injury (TBI) is a major cause of death and permanent disability. Systemic hypothermia, a treatment used in TBI for many decades, has recently been found to be associated with neutral or unfavourable clinical outcomes despite apparently promising preclinical research. Systematic review

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2016 Evidence-based preclinical medicine

102. Sertraline for Preventing Mood Disorders Following Traumatic Brain Injury: A Randomized Clinical Trial.

Sertraline for Preventing Mood Disorders Following Traumatic Brain Injury: A Randomized Clinical Trial. Prevention is more effective than treatment to decrease the burden of significant medical conditions such as depressive disorders, a major cause of disability worldwide. Traumatic brain injury (TBI) is a candidate for selective strategies to prevent depression given the incidence, prevalence, and functional effect of depression that occurs after TBI.To assess the efficacy of sertraline

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2016 EvidenceUpdates

103. Clinical practice guideline for the rehabilitation of adults with moderate to severe Traumatic Brain Injury

Clinical practice guideline for the rehabilitation of adults with moderate to severe Traumatic Brain Injury Brain Injury Guidelines - Ontario Neurotrauma Foundation (ONF) Welcome to braininjuryguidelines.org INESSS-ONF CLINICAL PRACTICE GUIDELINE FOR THE REHABILITATION OF ADULTS WITH MODERATE TO SEVERE TBI GUIDELINE FOR CONCUSSION/MILD TRAUMATIC BRAIN INJURY & PERSISTENT SYMPTOMS 3RD EDITION, FOR ADULTS OVER 18 YEARS OF AGE

2016 CPG Infobase

104. Management of severe traumatic brain injury and acute respiratory distress syndrome using pumped extracorporeal carbon dioxide removal device (PubMed)

Management of severe traumatic brain injury and acute respiratory distress syndrome using pumped extracorporeal carbon dioxide removal device The effects of a high carbon dioxide on cerebral perfusion and intracranial pressure are well known. We report the case of a man who presented after with a severe traumatic brain injury including intracranial and extradural haemorrhage. Neuroprotective ventilation was impossible without supramaximal tidal volumes due to a combination of chest trauma

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2016 Journal of the Intensive Care Society

105. Randomised, waiting list controlled trial of cognitive-behavioural therapy for persistent postconcussional symptoms after predominantly mild-moderate traumatic brain injury (PubMed)

Randomised, waiting list controlled trial of cognitive-behavioural therapy for persistent postconcussional symptoms after predominantly mild-moderate traumatic brain injury Persistent postconcussional symptoms (PCS) can be a source of distress and disability following traumatic brain injury (TBI). Such symptoms have been viewed as difficult to treat but may be amenable to psychological approaches such as cognitive-behavioural therapy (CBT).To evaluate the effectiveness of a 12-session (...) individualised, formulation-based CBT programme.Two-centre randomised waiting list controlled trial with 46 adults with persistent PCS after predominantly mild-to-moderate TBI (52% with post-traumatic amnesia (PTA)≤24 hours), but including some with severe TBIs (20% with PTA>7 days).Improvements associated with CBT were found on the primary outcome measures relating to quality of life (using the Quality of Life Assessment Schedule and the Brain Injury Community Rehabilitation Outcome Scale). Treatment

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2016 EvidenceUpdates Controlled trial quality: uncertain

106. Vitamin K, fresh frozen plasma, and platelet transfusion used to arrest progression of intracranial hemorrhage after traumatic brain injury in a patient taking anticoagulant and antiplatelet agents (PubMed)

Vitamin K, fresh frozen plasma, and platelet transfusion used to arrest progression of intracranial hemorrhage after traumatic brain injury in a patient taking anticoagulant and antiplatelet agents An 89-year-old man fell from stairs and sustained head trauma. He was taking warfarin and aspirin. Upon arrival at our hospital, his Glasgow Coma Scale score was 14. Initial head computed tomography showed small acute subdural hematoma. We immediately administered vitamin K and ordered fresh-frozen (...) progression of traumatic intracranial hemorrhages in this patient taking anticoagulant/antiplatelet agents and may have averted brain surgery.

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2016 Acute medicine & surgery

107. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. (PubMed)

Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. 27050212 2016 04 07 2018 12 02 1533-4406 374 14 2016 04 07 The New England journal of medicine N. Engl. J. Med. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. 1385 10.1056/NEJMc1600339 Andrews Peter J D PJ Harris Bridget A BA Murray Gordon D GD eng Letter Comment United States N Engl J Med 0255562 0028-4793 AIM IM N Engl J Med. 2015 Dec 17;373(25):2403-12 26444221 N Engl J Med. 2016 Apr 7;374(14 (...) ):1383-4 27050213 N Engl J Med. 2016 Apr 7;374(14):1384 27050214 N Engl J Med. 2016 Apr 7;374(14):1384 27050215 Brain Injuries complications Humans Hypothermia, Induced Intracranial Hypertension therapy 2016 4 7 6 0 2016 4 7 6 0 2016 4 8 6 0 ppublish 27050212 10.1056/NEJMc1600339 10.1056/NEJMc1600339#SA4

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2016 NEJM

108. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. (PubMed)

Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. 27050213 2016 04 07 2018 12 02 1533-4406 374 14 2016 04 07 The New England journal of medicine N. Engl. J. Med. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. 1383-4 10.1056/NEJMc1600339 O'Leary Ronan R Addenbrooke's Hospital, Cambridge, United Kingdom. Hutchinson Peter J A PJ University of Cambridge, Cambridge, United Kingdom dkm13@wbic.cam.ac.uk. Menon David D University of Cambridge, Cambridge (...) , United Kingdom dkm13@wbic.cam.ac.uk. eng Letter Comment United States N Engl J Med 0255562 0028-4793 AIM IM N Engl J Med. 2015 Dec 17;373(25):2403-12 26444221 N Engl J Med. 2016 Apr 7;374(14):1385 27050212 Brain Injuries complications Humans Hypothermia, Induced Intracranial Hypertension therapy 2016 4 7 6 0 2016 4 7 6 0 2016 4 8 6 0 ppublish 27050213 10.1056/NEJMc1600339 10.1056/NEJMc1600339#SA1

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2016 NEJM

109. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. (PubMed)

Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. 27050214 2016 04 07 2018 12 02 1533-4406 374 14 2016 04 07 The New England journal of medicine N. Engl. J. Med. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. 1384 10.1056/NEJMc1600339 Lazaridis Christos C Baylor College of Medicine, Houston, TX lazaridi@bcm.edu. eng Letter Comment United States N Engl J Med 0255562 0028-4793 AIM IM N Engl J Med. 2015 Dec 17;373(25):2403-12 26444221 N Engl J Med (...) . 2016 Apr 7;374(14):1385 27050212 Brain Injuries complications Humans Hypothermia, Induced Intracranial Hypertension therapy 2016 4 7 6 0 2016 4 7 6 0 2016 4 8 6 0 ppublish 27050214 10.1056/NEJMc1600339 10.1056/NEJMc1600339#SA2

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2016 NEJM

110. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. (PubMed)

Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. 27050215 2016 04 07 2018 12 02 1533-4406 374 14 2016 04 07 The New England journal of medicine N. Engl. J. Med. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. 1384 10.1056/NEJMc1600339 Cooper D James DJ Monash University, Melbourne, VIC, Australia jamie.cooper@monash.edu. Nichol Alistair A Monash University, Melbourne, VIC, Australia jamie.cooper@monash.edu. Presneill Jeffrey J Monash University (...) , Melbourne, VIC, Australia jamie.cooper@monash.edu. eng Letter Comment United States N Engl J Med 0255562 0028-4793 AIM IM N Engl J Med. 2015 Dec 17;373(25):2403-12 26444221 N Engl J Med. 2016 Apr 7;374(14):1385 27050212 Brain Injuries complications Humans Hypothermia, Induced Intracranial Hypertension therapy 2016 4 7 6 0 2016 4 7 6 0 2016 4 8 6 0 ppublish 27050215 10.1056/NEJMc1600339 10.1056/NEJMc1600339#SA3

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2016 NEJM

111. Does Mannitol Reduce Mortality From Traumatic Brain Injury?

Does Mannitol Reduce Mortality From Traumatic Brain Injury? Systematic Review Snapshot TAKE-HOME MESSAGE There is insuf?cient evidence to support the routine use of mannitol in the management of severe traumatic brain injury. Does Mannitol Reduce Mortality From Traumatic Brain Injury? EBEM Commentators Michael Gottlieb, MD John Bailitz, MD Department of Emergency Medicine Cook County Hospital Chicago, IL Results Four studies met the authors’ in- clusion criteria. Two trials com- pared mannitol (...) % mannitol vs placebo 1.75 (0.48–6.38) RR, Relative risk; CI, con?dence interval; TBI, traumatic brain injury; GCS, Glasgow Coma Scale; ICP, intracranial pressure. METHODS DATA SOURCES TheauthorssearchedtheCochrane InjuriesGroupSpecializedRegister, CENTRAL,MEDLINE,EMBASE, PubMed,ISIWebofScience,and ConferenceProceedingsCitation IndexfrominceptionuntilApril 2009.Thereferencelistsofrelevant articleswerealsoreviewedandthe ?rstauthorofselectedarticleswas contactedforassistancewith

2016 Annals of Emergency Medicine Systematic Review Snapshots

112. Management of Concussion-mild Traumatic Brain Injury (mTBI)

Management of Concussion-mild Traumatic Brain Injury (mTBI) VA/DoD CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF CONCUSSION-MILD TRAUMATIC BRAIN INJURY Department of Veterans Affairs Department of Defense QUALIFYING STATEMENTS The Department of Veterans Affairs and the Department of Defense guidelines are based upon the best information available at the time of publication. They are designed to provide information and assist decision making. They are not intended to define a standard (...) and/or therapeutic interventions within these guidelines does not guarantee coverage of civilian sector care. Additional information on current TRICARE benefits may be found at www.tricare.mil or by contacting your regional TRICARE Managed Care Support Contractor. Version 2.0 – 2016 VA/DoD Clinical Practice Guideline for the Management of Concussion-mild Traumatic Brain Injury February 2016 Page 2 of 133 Prepared by: The Management of Concussion-mild Traumatic Brain Injury Working Group With support from

2016 VA/DoD Clinical Practice Guidelines

113. Guidelines for the Management of Severe Traumatic Brain Injury (4th edition)

Guidelines for the Management of Severe Traumatic Brain Injury (4th edition) We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Guidelines for the Management of Severe Traumatic Brain Injury, Fourth Edition | Neurosurgery | Oxford Academic Search Account Menu Menu Navbar Search Filter Mobile Microsite Search Term Close search filter search input Article Navigation (...) Close mobile search navigation Article navigation January 2017 Article Contents Article Navigation Guidelines for the Management of Severe Traumatic Brain Injury, Fourth Edition Nancy Carney, PhD *Oregon Health & Science University, Portland, Oregon Search for other works by this author on: Annette M. Totten, PhD *Oregon Health & Science University, Portland, Oregon Search for other works by this author on: Cindy O'Reilly, BS *Oregon Health & Science University, Portland, Oregon Search for other

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2016 Congress of Neurological Surgeons

114. Non-pharmacological interventions for depression in adults and children with traumatic brain injury. (PubMed)

Non-pharmacological interventions for depression in adults and children with traumatic brain injury. Following traumatic brain injury (TBI) there is an increased prevalence of depression compared to the general population. It is unknown whether non-pharmacological interventions for depression are effective for people with TBI.To investigate the effectiveness of non-pharmacological interventions for depression in adults and children with TBI at reducing the diagnosis and severity of symptoms (...) of depression.We ran the most recent search on 11 February 2015. We searched the Cochrane Injuries Group Specialised Register, The Cochrane Library, MEDLINE (OvidSP), Embase (OvidSP), three other databases and clinical trials registers. Relevant conference proceedings and journals were handsearched, as were the reference lists of identified studies.Randomised controlled trials (RCTs) of non-pharmacological interventions for depression in adults and children who had a TBI.Two authors independently selected

2015 Cochrane

115. Urban/Rural disparities in Oregon pediatric traumatic brain injury (PubMed)

Urban/Rural disparities in Oregon pediatric traumatic brain injury Traumatic brain injury (TBI) greatly contributes to morbidity and mortality in the pediatric population. We examined potential urban/rural disparities in mortality amongst Oregon pediatric patients with TBI treated in trauma hospitals.We conducted a retrospective study of children ages 0-19 using the Oregon Trauma Registry for years 2009-2012. Geographic location of injury was classified using the National Center for Health (...) Statistics Urban/Rural Classification Scheme. Incidence rates were calculated using Census data for denominators. Associations between urban/rural injury location and mortality were assessed using multivariable logistic regression, controlling for potential confounders. Generalized estimating equations were used to help account for clustering of data within hospitals.Of 2794 pediatric patients with TBI, 46.6 % were injured in large metropolitan locations, 24.8 % in medium/small metropolitan locations

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2015 Injury epidemiology

116. Hypothermia for Traumatic Brain Injury in Children-A Phase II Randomized Controlled Trial

Hypothermia for Traumatic Brain Injury in Children-A Phase II Randomized Controlled Trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2015 PedsCCM Evidence-Based Journal Club

117. Care Transitions to and from the National Intrepid Center of Excellence (NICoE) for Service Members with Traumatic Brain Injury (PubMed)

Care Transitions to and from the National Intrepid Center of Excellence (NICoE) for Service Members with Traumatic Brain Injury Improvised explosive devices (IEDs) have been one of the leading causes of death and injury among U.S. troops. Those who survive an IED blast or other injuries may be left with a traumatic brain injury (TBI) and attendant or co-occurring psychological symptoms. In response to the need for specialized services for these populations, the U.S. Department of Defense (DoD

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2015 Rand health quarterly

118. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. (PubMed)

Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. In patients with traumatic brain injury, hypothermia can reduce intracranial hypertension. The benefit of hypothermia on functional outcome is unclear.We randomly assigned adults with an intracranial pressure of more than 20 mm Hg despite stage 1 treatments (including mechanical ventilation and sedation management) to standard care (control group) or hypothermia (32 to 35°C) plus standard care. In the control group, stage 2 (...) traumatic brain injury, therapeutic hypothermia plus standard care to reduce intracranial pressure did not result in outcomes better than those with standard care alone. (Funded by the National Institute for Health Research Health Technology Assessment program; Current Controlled Trials number, ISRCTN34555414.).

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2015 NEJM Controlled trial quality: predicted high

119. Telerehabilitation for Pediatric Patients with Traumatic Brain Injury: Clinical Effectiveness, Cost-Effectiveness, and Guidelines

Telerehabilitation for Pediatric Patients with Traumatic Brain Injury: Clinical Effectiveness, Cost-Effectiveness, and Guidelines Telerehabilitation for Pediatric Patients with Traumatic Brain Injury: Clinical Effectiveness, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Telerehabilitation for Pediatric Patients with Traumatic Brain Injury: Clinical Effectiveness, Cost-Effectiveness, and Guidelines Telerehabilitation for Pediatric Patients with Traumatic Brain (...) Injury: Clinical Effectiveness, Cost-Effectiveness, and Guidelines Published on: July 17, 2015 Project Number: RB0887-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What is the clinical effectiveness of telerehabilitation for pediatric patients with traumatic brain injury? What is the cost-effectiveness of telerehabilitation for pediatric patients with traumatic brain injury? What are the evidence-based guidelines regarding the use

2015 Canadian Agency for Drugs and Technologies in Health - Rapid Review

120. Very Early Administration of Progesterone for Acute Traumatic Brain Injury

Very Early Administration of Progesterone for Acute Traumatic Brain Injury PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2015 PedsCCM Evidence-Based Journal Club