Latest & greatest articles for traumatic brain injury

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Top results for traumatic brain injury

81. Guidelines for concussion/mild traumatic brain injury & persistent symptoms: second edition - for adults (18+ years of age)

Guidelines for concussion/mild traumatic brain injury & persistent symptoms: second edition - for adults (18+ years of age)

CMA Infobase (Canada)2013

82. Interventions provided in the acute phase for mild traumatic brain injury: a systematic review

Interventions provided in the acute phase for mild traumatic brain injury: a systematic review Interventions provided in the acute phase for mild traumatic brain injury: a systematic review Interventions provided in the acute phase for mild traumatic brain injury: a systematic review Gravel J, D'Angelo A, Carriere B, Crevier L, Beauchamp MH, Chauny JM, Wassef M, Chaillet N CRD summary This review concluded that there was a paucity of well-designed clinical trials for patients who sustain mild (...) traumatic brain injury. The large variability in outcomes measured in the included trials limited comparison between them. This was a well-conducted review and the authors' conclusion seems appropriate and reliable. Authors' objectives To evaluate interventions that could be initiated in an acute setting for patients who sustain a mild traumatic brain injury. Searching PubMed, EMBASE, PsycINFO, CINAHL, Cochrane Central Register of Controlled Trials (CENTRAL), EBM Reviews, and ACP Journal Club were

DARE.2013

83. A prospective, randomized Phase II clinical trial to evaluate the effect of combined hyperbaric and normobaric hyperoxia on cerebral metabolism, intracranial pressure, oxygen toxicity, and clinical outcome in severe traumatic brain injury

A prospective, randomized Phase II clinical trial to evaluate the effect of combined hyperbaric and normobaric hyperoxia on cerebral metabolism, intracranial pressure, oxygen toxicity, and clinical outcome in severe traumatic brain injury 23510092 2013 06 03 2013 09 25 2015 11 19 1933-0693 118 6 2013 Jun Journal of neurosurgery J. Neurosurg. A prospective, randomized Phase II clinical trial to evaluate the effect of combined hyperbaric and normobaric hyperoxia on cerebral metabolism (...) , intracranial pressure, oxygen toxicity, and clinical outcome in severe traumatic brain injury. 1317-28 10.3171/2013.2.JNS121468 Preclinical and clinical investigations indicate that the positive effect of hyperbaric oxygen (HBO2) for severe traumatic brain injury (TBI) occurs after rather than during treatment. The brain appears better able to use baseline O2 levels following HBO2 treatments. In this study, the authors evaluate the combination of HBO2 and normobaric hyperoxia (NBH) as a single treatment

EvidenceUpdates2013

84. Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial

Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial 23664370 2013 05 20 2013 07 22 2016 06 29 1474-4465 12 6 2013 Jun The Lancet. Neurology Lancet Neurol Comparison of hypothermia and normothermia after severe traumatic brain injury in children (Cool Kids): a phase 3, randomised controlled trial. 546-53 10.1016/S1474-4422(13)70077-2 S1474-4422(13)70077-2 On the basis of mixed results from previous trials (...) , we assessed whether therapeutic hypothermia for 48-72 h with slow rewarming improved mortality in children after brain injury. In this phase 3, multicenter, multinational, randomised controlled trial, we included patients with severe traumatic brain injury who were younger than 18 years and could be enrolled within 6 h of injury. We used a computer-generated randomisation sequence to randomly allocate patients (1:1; stratified by site and age [<6 years, 6-15 years, 16-17 years]) to either

EvidenceUpdates2013

85. Mannitol for acute traumatic brain injury.

Mannitol for acute traumatic brain injury. BACKGROUND: Mannitol is sometimes effective in reversing acute brain swelling, but its effectiveness in the ongoing management of severe head injury remains unclear. There is evidence that, in prolonged dosage, mannitol may pass from the blood into the brain, where it might cause increased intracranial pressure. OBJECTIVES: To assess the effects of different mannitol therapy regimens, of mannitol compared to other intracranial pressure (ICP) lowering (...) agents, and to quantify the effectiveness of mannitol administration given at other stages following acute traumatic brain injury. SEARCH METHODS: We searched the Cochrane Injuries Group Specialised Register, CENTRAL (The Cochrane Library), MEDLINE (OvidSP), EMBASE (OvidSP), ISI Web of Science (SCI-EXPANDED & CPCI-S) and PubMed. We checked reference lists of trials and review articles, and contacted authors of trials. The search was updated on the 20th April 2009. SELECTION CRITERIA: Randomised

Cochrane2013

86. A Trial of Intracranial-Pressure Monitoring in Traumatic Brain Injury

A Trial of Intracranial-Pressure Monitoring in Traumatic Brain Injury PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2013

88. Disparities in Disability After Traumatic Brain Injury Among Hispanic Children and Adolescents

Disparities in Disability After Traumatic Brain Injury Among Hispanic Children and Adolescents 23650302 2013 06 04 2013 08 16 2017 02 20 1098-4275 131 6 2013 Jun Pediatrics Pediatrics Disparities in disability after traumatic brain injury among Hispanic children and adolescents. e1850-6 10.1542/peds.2012-3354 To compare the extent of disability in multiple areas of functioning after mild, moderate, and severe traumatic brain injury (TBI) between Hispanic and non-Hispanic white (NHW) children (...) Disability Evaluation Ethnic Groups Female Follow-Up Studies Health Status Disparities Hispanic Americans Humans Infant Infant, Newborn Male Prospective Studies Quality of Life Surveys and Questionnaires PMC3666112 Hispanic children disability disparities traumatic brain injury 2013 5 8 6 0 2013 5 8 6 0 2013 8 21 6 0 ppublish 23650302 peds.2012-3354 10.1542/peds.2012-3354 PMC3666112

EvidenceUpdates2013 Full Text: Link to full Text with Trip Pro

89. Complications of Mild Traumatic Brain Injury in Veterans and Military Personnel

Complications of Mild Traumatic Brain Injury in Veterans and Military Personnel Management Briefs Search the HSR&D website Button to search HSRD ® Inside VA Budget and Performance Inside the News Room National Observances Special Events » » » » » Management Briefs Health Services Research & Development Management Briefs Management Briefs: Provide VA senior managers with results from VA Health Services Research in a concise and timely manner. , February 2017, Issue 122 , February 2017, Issue 122

Veterans Affairs - R&D2013

90. Multidisciplinary Rehabilitation Programs for Moderate to Severe Traumatic Brain Injury in Adults: Future Research Needs

Multidisciplinary Rehabilitation Programs for Moderate to Severe Traumatic Brain Injury in Adults: Future Research Needs

Effective Health Care Program (AHRQ)2013

91. Cognitive function and other risk factors for mild traumatic brain injury in young men: nationwide cohort study.

Cognitive function and other risk factors for mild traumatic brain injury in young men: nationwide cohort study. OBJECTIVE: To investigate cognitive function and other risk factors for mild traumatic brain injury in young men. DESIGN: Nationwide prospective cohort study. SETTING: Sweden. PARTICIPANTS: 305 885 men conscripted for military service from 1989 to 1994. MAIN OUTCOME MEASURE: mild traumatic brain injuries in relation to cognitive function and other potential risk factors assessed (...) at conscription and follow-up. RESULTS: Men with one mild traumatic brain injury within two years before (n=1988) or after cognitive testing (n=2214) had about 5.5% lower overall cognitive function scores than did men with no mild traumatic brain injury during follow up (P<0.001 for both). Moreover, men with at least two mild traumatic brain injuries after cognitive testing (n=795) had 15% lower overall cognitive function scores compared with those with no such injury (P<0.001). Independent strong risk

BMJ2013

92. Postconcussive Complaints, Anxiety, and Depression Related to Vocational Outcome in Minor to Severe Traumatic Brain Injury

Postconcussive Complaints, Anxiety, and Depression Related to Vocational Outcome in Minor to Severe Traumatic Brain Injury 23220341 2013 04 26 2013 06 24 2015 11 19 1532-821X 94 5 2013 May Archives of physical medicine and rehabilitation Arch Phys Med Rehabil Postconcussive complaints, anxiety, and depression related to vocational outcome in minor to severe traumatic brain injury. 867-74 10.1016/j.apmr.2012.11.039 S0003-9993(12)01203-8 To investigate the relation of postconcussive complaints (...) , anxiety, and depression with vocational outcome in patients with traumatic brain injury (TBI) of various severities and to assess sex differences. A prospective cross-sectional cohort study. Level I trauma center. Adults (N=242) with TBI of various severity. Not applicable. Extended Glasgow Outcome Scale, return to work (RTW), Head Injury Symptom Checklist, and Hospital Anxiety and Depression Scale. In 67% of the patients, complaints were present; 22% were anxious, and 18% were depressed

EvidenceUpdates2013

93. A cost-minimization analysis of phenytoin versus levetiracetam for early seizure pharmacoprophylaxis after traumatic brain injury

A cost-minimization analysis of phenytoin versus levetiracetam for early seizure pharmacoprophylaxis after traumatic brain injury A cost-minimization analysis of phenytoin versus levetiracetam for early seizure pharmacoprophylaxis after traumatic brain injury A cost-minimization analysis of phenytoin versus levetiracetam for early seizure pharmacoprophylaxis after traumatic brain injury Pieracci FM, Moore EE, Beauchamp K, Tebockhorst S, Barnett CC, Bensard DD, Burlew CC, Biffl WL, Stoval RT (...) , Johnson JL Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study examined the clinical and economic impact of levetiracetam, compared with phenytoin, to prevent early seizures after traumatic brain injury. The authors concluded

NHS Economic Evaluation Database.2013

94. Reliable Change in Postconcussive Symptoms and Its Functional Consequences Among Children With Mild Traumatic Brain Injury

Reliable Change in Postconcussive Symptoms and Its Functional Consequences Among Children With Mild Traumatic Brain Injury 22393171 2013 02 11 2013 02 12 2017 02 20 1538-3628 166 7 2012 Jul 01 Archives of pediatrics & adolescent medicine Arch Pediatr Adolesc Med Reliable change in postconcussive symptoms and its functional consequences among children with mild traumatic brain injury. 615-22 10.1001/archpediatrics.2011.1082 OBJECTIVE To examine reliable change in postconcussive symptoms and its (...) functional consequences among children with mild traumatic brain injury (TBI) over the first year postinjury as compared with children with orthopedic injuries. DESIGN Prospective, longitudinal cohort. SETTING Emergency departments at 2 children's hospitals. PARTICIPANTS Eight- to 15-year-old children with mild TBI (n = 186) or orthopedic injuries (n = 99). MAIN EXPOSURE Closed-head or orthopedic trauma. MAIN OUTCOME MEASURES Parents rated preinjury symptoms retrospectively shortly after injury

EvidenceUpdates2013 Full Text: Link to full Text with Trip Pro

95. Protocol management of severe traumatic brain injury in intensive care units: a systematic review

Protocol management of severe traumatic brain injury in intensive care units: a systematic review Protocol management of severe traumatic brain injury in intensive care units: a systematic review Protocol management of severe traumatic brain injury in intensive care units: a systematic review English SW, Turgeon AF, Owen E, Doucette S, Pagliarello G, McIntyre L CRD summary The review concluded that management protocols (or care pathways) for severe traumatic brain injury were associated (...) with reductions in death rate and improved neurologic outcome, although no definitive conclusions about efficacy can be made due to limitations of the included studies. These conclusions were suitably cautious in reflecting the limited evidence available, and the recommendations for further research were appropriate. Authors' objectives To compare the use of management protocols (or care pathways) versus usual care for adult intensive care unit patients with acute severe traumatic brain injury. Searching Ten

DARE.2013

96. BHR-100 for severe traumatic brain injury ? first line

BHR-100 for severe traumatic brain injury ? first line BHR-100 for severe traumatic brain injury – first line BHR-100 for severe traumatic brain injury – first line NIHR HSC Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation NIHR HSC. BHR-100 for severe traumatic brain injury – first line. Birmingham: NIHR Horizon Scanning Centre (NIHR HSC (...) ). Horizon Scanning Review. 2013 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Brain Injuries; Progesterones Language Published English Country of organisation England English summary An English language summary is available. Address for correspondence The NIHR Horizon Scanning Centre, Department of Public Health, Epidemiology, and Biostatistics, School of Health&Population Sciences, University of Birmingham, 90 Vincent Drive, Edgbaston, Birmingham, B15 2SP. United Kingdom

Health Technology Assessment (HTA) Database.2013

97. Systematic review of head cooling in adults after traumatic brain injury and stroke

Systematic review of head cooling in adults after traumatic brain injury and stroke Systematic review of head cooling in adults after traumatic brain injury and stroke Journals Library An error has occurred in processing the XML document An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you

NIHR HTA programme2012

98. A prospective study on employment outcome 3 years after moderate to severe traumatic brain injury

A prospective study on employment outcome 3 years after moderate to severe traumatic brain injury 22502806 2012 05 28 2012 08 02 2012 05 28 1532-821X 93 6 2012 Jun Archives of physical medicine and rehabilitation Arch Phys Med Rehabil A prospective study on employment outcome 3 years after moderate to severe traumatic brain injury. 993-9 10.1016/j.apmr.2012.01.018 To evaluate the employment outcome in patients with moderate to severe traumatic brain injury (TBI) and to identify which patients (...) Ian K IK Ribbers Gerard M GM eng Comparative Study Journal Article 2012 04 12 United States Arch Phys Med Rehabil 2985158R 0003-9993 AIM IM Adolescent Adult Aged Analysis of Variance Brain Injuries diagnosis rehabilitation Cognition Disorders diagnosis rehabilitation Cohort Studies Depression diagnosis rehabilitation Employment statistics & numerical data Female Follow-Up Studies Glasgow Coma Scale Humans Injury Severity Score Logistic Models Male Middle Aged Multivariate Analysis Netherlands

EvidenceUpdates2012

99. Early management of severe traumatic brain injury.

Early management of severe traumatic brain injury. Severe traumatic brain injury remains a major health-care problem worldwide. Although major progress has been made in understanding of the pathophysiology of this injury, this has not yet led to substantial improvements in outcome. In this report, we address present knowledge and its limitations, research innovations, and clinical implications. Improved outcomes for patients with severe traumatic brain injury could result from progress (...) in pharmacological and other treatments, neural repair and regeneration, optimisation of surgical indications and techniques, and combination and individually targeted treatments. Expanded classification of traumatic brain injury and innovations in research design will underpin these advances. We are optimistic that further gains in outcome for patients with severe traumatic brain injury will be achieved in the next decade. Copyright © 2012 Elsevier Ltd. All rights reserved.

Lancet2012

100. Specialized neurocritical care units for traumatic brain injury

Specialized neurocritical care units for traumatic brain injury Specialized neurocritical care units for traumatic brain injury Specialized neurocritical care units for traumatic brain injury Mitchell MD, Williams K Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mitchell MD, Williams K. Specialized neurocritical care units for traumatic brain injury (...) . Philadelphia: Center for Evidence-based Practice (CEP). 2012 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Brain Injuries; Critical Cares; Intensive Care Units; Outcome and Process Assessment (Health Care) Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence Center for Evidence-based Practice, University of Pennsylvania Health System, 3535 Market St. Suite 50, Philadelphia PA 19104

Health Technology Assessment (HTA) Database.2012