Latest & greatest articles for traumatic brain injury

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Top results for traumatic brain injury

261. A systematic review of differences between brain temperature and core body temperature in adult patients with severe traumatic brain injury. (Abstract)

A systematic review of differences between brain temperature and core body temperature in adult patients with severe traumatic brain injury. Studies have shown that temperature at the extremes of the thermoregulatory physiological range, commensurate with a clinical diagnosis of hypothermia (at the lower end) and hyperthermia or fever (at the upper end) increase the risk of a poor neurological outcome and contribute to higher mortality. The tissue most at risk is nervous tissue. That said (...) (or fall) in brain temperature beyond the 'normal' range is suspected.This systematic review focused on whether brain temperature is higher, lower, or the same as core body temperature in patients with severe traumatic brain injury.This review considered studies that include male and female patients, aged 15 years and above, admitted to an adult Intensive Care Unit, with the diagnosis of severe traumatic brain injury, with a Glasgow Coma Scale score of less than eight, and who require brain temperature

2017 JBI library of systematic reviews

262. Cerebrospinal Fluid and Microdialysis Cytokines in Severe Traumatic Brain Injury: A Scoping Systematic Review. (Full text)

Cerebrospinal Fluid and Microdialysis Cytokines in Severe Traumatic Brain Injury: A Scoping Systematic Review. To perform two scoping systematic reviews of the literature on cytokine measurement in: 1. cerebral microdialysis (CMD) and 2. cerebrospinal fluid (CSF) in severe traumatic brain injury (TBI) patients.Two separate systematic reviews were conducted: one for CMD cytokines and the second for CSF cytokines. Both were conducted in severe TBI (sTBI) patients only.Articles from MEDLINE

2017 Frontiers in neurology PubMed abstract

263. Incidence, Demographics and Outcome of Traumatic Brain Injury in The Middle East: A Systematic Review. (Abstract)

Incidence, Demographics and Outcome of Traumatic Brain Injury in The Middle East: A Systematic Review. Traumatic brain injury (TBI) is a serious global public health challenge. We aimed to assess the pattern of TBI in the Middle East, as reported in the last decade.Literature searches were conducted on PubMed, MEDLINE, and Google scholar electronic databases. The search terms used in different combinations were epidemiology, incidence, case fatality, mortality, intracranial injury, brain injury (...) , head injury, and the country names. Additional searches were conducted using reference lists of studies and review articles for selection of relevant articles. The search yielded 1082 articles; of which 701 duplicates and 346 articles were excluded. Thirty-five original studies met the inclusion criteria. Data were extracted using standardized Excel form and pilot tested. Median with interquartile range (IQR) was used to estimate the incidence rate and mortality of TBI.In the Middle East region

2017 World neurosurgery

264. A systematic review of peer mentoring interventions for people with traumatic brain injury. (Full text)

A systematic review of peer mentoring interventions for people with traumatic brain injury. This systematic review sought evidence concerning the effectiveness of peer mentoring for people with traumatic brain injury.Fourteen electronic databases were searched, including PsycINFO, MEDLINE, CINAHL, EMBASE and the Cochrane Library, from inception to September 21 2016. Ten grey literature databases, PROSPERO, two trials registers, reference lists and author citations were also searched.Studies (...) which employed a model of one-to-one peer mentoring between traumatic brain injury survivors were included. Two reviewers independently screened all titles and abstracts before screening full texts of shortlisted studies. A third reviewer resolved disagreements. Two reviewers independently extracted data and assessed studies for quality and risk of bias.The search returned 753 records, including one identified through hand searching. 495 records remained after removal of duplicates and 459 were

2017 Clinical rehabilitation PubMed abstract

265. Serial Sampling of Serum Protein Biomarkers for Monitoring Human Traumatic Brain Injury Dynamics: A Systematic Review. (Full text)

Serial Sampling of Serum Protein Biomarkers for Monitoring Human Traumatic Brain Injury Dynamics: A Systematic Review. The proteins S100B, neuron-specific enolase (NSE), glial fibrillary acidic protein (GFAP), ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), and neurofilament light (NF-L) have been serially sampled in serum of patients suffering from traumatic brain injury (TBI) in order to assess injury severity and tissue fate. We review the current literature of serum level dynamics (...) frequent biomarkers that were serially sampled. For S100B in severe TBI, a majority of studies indicate a t1/2 of about 24 h, even if very early sampling in these patients reveals rapid decreases (1-2 h) though possibly of non-cerebral origin. In contrast, the t1/2 for NSE is comparably longer, ranging from 48 to 72 h in severe TBI cases. The protein GFAP (n = 18) appears to have t1/2 of about 24-48 h in severe TBI. The protein UCH-L1 (n = 9) presents a t1/2 around 7 h in mild TBI and about 10 h

2017 Frontiers in neurology PubMed abstract

266. Mannitol cannot reduce the mortality on acute severe traumatic brain injury (TBI) patients: a meta-analyses and systematic review. (Full text)

Mannitol cannot reduce the mortality on acute severe traumatic brain injury (TBI) patients: a meta-analyses and systematic review. We aimed to systematically review the efficacy of mannitol (MTL) on patients with acute severe traumatic brain injury (TBI).Databases such as PubMed (US National Library of Medicine), CENTRAL (The Cochrane Library 2014, Issue 3), ISI (Web of Science: Science Citation Index Expanded), Chinese Biomedicine Database (CBM), and China Knowledge Resource Integrated (...) with diffuse brain injuries than mannitol did.As a conclusion, the mannitol therapy cannot reduce the mortality risk of acute severe traumatic brain injury. Current evidence does not support the mannitol as an effective treatment of acute severe traumatic brain injury. The well-designed randomized controlled trials are in urgent need to demonstrate the adoption of mannitol to acute severe traumatic brain injury.

2017 Burns & trauma PubMed abstract

267. The clinical significance of isolated traumatic subarachnoid hemorrhage in mild traumatic brain injury: A meta-analysis. (Abstract)

The clinical significance of isolated traumatic subarachnoid hemorrhage in mild traumatic brain injury: A meta-analysis. The rates of clinical and radiographic progression and the need for neurosurgical intervention in patients with isolated traumatic subarachnoid hemorrhage (itSAH) after mild traumatic brain injury (Glasgow Coma Scale score, 13-15) has not been well established.The aim of this work was to review the evidence regarding patient outcomes after mild traumatic brain injury

2017 The journal of trauma and acute care surgery

268. Neuropsychological Predictors of Outcome Following Traumatic Brain Injury in Adults: a Meta-Analysis. (Abstract)

Neuropsychological Predictors of Outcome Following Traumatic Brain Injury in Adults: a Meta-Analysis. Several neuropsychological dimensions are correlated with functional outcome (e.g., ability to return to family and community roles) following traumatic brain injury (TBI). Commonly investigated neuropsychological dimensions include verbal memory, visuo-spatial construction, set-shifting, generativity, and processing speed. Unfortunately, small sample sizes across relevant studies have

2017 Neuropsychology review

269. Meta-Analysis of Therapeutic Hypothermia for Traumatic Brain Injury in Adult and Pediatric Patients

Meta-Analysis of Therapeutic Hypothermia for Traumatic Brain Injury in Adult and Pediatric Patients PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2017 PedsCCM Evidence-Based Journal Club

270. Acute Alcohol Exposure and Risk of Mortality of Patients with Traumatic Brain Injury: A Systematic Review and Meta-analysis. (Abstract)

Acute Alcohol Exposure and Risk of Mortality of Patients with Traumatic Brain Injury: A Systematic Review and Meta-analysis. After traumatic brain injury (TBI), patients usually live with significant disability and socioeconomic burdens. Acute exposure to alcohol is considered a major risk factor for TBI. Numerous studies have examined whether alcohol exposure is related to the risk of mortality in patients with TBI, yet the results remain inconsistent. We performed a meta-analysis to assess

2017 Alcoholism, clinical and experimental research

271. Cognitive rehabilitation for adults with traumatic brain injury to improve occupational outcomes. (Full text)

Cognitive rehabilitation for adults with traumatic brain injury to improve occupational outcomes. Cognitive impairment in people with traumatic brain injury (TBI) could affect multiple facets of their daily functioning. Cognitive rehabilitation brings about clinically significant improvement in certain cognitive skills. However, it is uncertain if these improved cognitive skills lead to betterments in other key aspects of daily living. We evaluated whether cognitive rehabilitation for people (...) with TBI improves return to work, independence in daily activities, community integration and quality of life.To evaluate the effects of cognitive rehabilitation on return to work, independence in daily activities, community integration (occupational outcomes) and quality of life in people with traumatic brain injury, and to determine which cognitive rehabilitation strategy better achieves these outcomes.We searched CENTRAL (the Cochrane Library; 2017, Issue 3), MEDLINE (OvidSP), Embase (OvidSP

2017 Cochrane PubMed abstract

272. Detecting social-cognitive deficits after traumatic brain injury: An ALE meta-analysis of fMRI studies. (Abstract)

Detecting social-cognitive deficits after traumatic brain injury: An ALE meta-analysis of fMRI studies. Traumatic brain injury (TBI) can result in significant social dysfunction, which is represented by impairment to social-cognitive abilities (i.e. social cognition, social attention/executive function and communication). This study is aimed to explore brain networks mediating the social dysfunction after TBI and its underlying mechanisms.We performed a quantitative meta-analysis using

2017 Brain Injury

273. Preclinical progenitor cell therapy in traumatic brain injury: a meta-analysis. (Full text)

Preclinical progenitor cell therapy in traumatic brain injury: a meta-analysis. No treatment is available to reverse injury associated with traumatic brain injury (TBI). Progenitor cell therapies show promise in both preclinical and clinical studies. We conducted a meta-analysis of preclinical studies using progenitor cells to treat TBI.EMBASE, MEDLINE, Cochrane Review, Biosis, and Google Scholar were searched for articles using prespecified search strategies. Studies meeting inclusion criteria

2017 The Journal of surgical research PubMed abstract

274. Growing Literature but Limited Evidence: A Systematic Review regarding Prebiotic and Probiotic Interventions for those with Traumatic Brain Injury and/or Posttraumatic Stress Disorder. (Abstract)

Growing Literature but Limited Evidence: A Systematic Review regarding Prebiotic and Probiotic Interventions for those with Traumatic Brain Injury and/or Posttraumatic Stress Disorder. Traumatic brain injury (TBI) is highly prevalent among a wide range of populations, including civilians, military personnel, and Veterans. TBI sequelae may be further exacerbated by symptoms associated with frequently occurring comorbid psychiatric conditions, including posttraumatic stress disorder (PTSD

2017 Brain, behavior, and immunity

275. Therapeutic effect of beta-blocker in patients with traumatic brain injury: A systematic review and meta-analysis. (Abstract)

Therapeutic effect of beta-blocker in patients with traumatic brain injury: A systematic review and meta-analysis. β-Blocker exposure has been shown to reduce mortality in traumatic brain injury (TBI); however, the efficacy of β-blockers remains inconclusive. Therefore, a meta-analysis was conducted in this paper to evaluate the safety and efficacy of β-blocker therapy on patients with TBI.The electronic databases were systemically retrieved from construction to February 2017. The odds ratio

2017 Journal of critical care

276. Correlations between diffusion tensor imaging and levels of consciousness in patients with traumatic brain injury: a systematic review and meta-analysis. (Full text)

Correlations between diffusion tensor imaging and levels of consciousness in patients with traumatic brain injury: a systematic review and meta-analysis. Traumatic brain injury (TBI) often leads to impaired consciousness. Recent diffusion tensor imaging studies associated consciousness with imaging metrics including fractional anisotropy (FA) and apparent diffusion coefficient (ADC). We evaluated their correlations and determined the best index in candidate regions. Six databases were searched (...) , including PubMed and Embase, and 16 studies with 701 participants were included. Data from region-of-interest and whole-brain analysis methods were meta-analysed separately. The FA-consciousness correlation was marginal in the whole-brain white matter (r = 0.63, 95% CI [0.47, 0.79], p = 0.000) and the corpus callosum (CC) (r = 0.60, 95% CI [0.48, 0.71], p = 0.000), and moderate in the internal capsule (r = 0.48, 95% CI [0.24, 0.72], p = 0.000). Correlations with ADC trended negative and lacked

2017 Scientific reports PubMed abstract

277. Intensive care for pediatric traumatic brain injury

Intensive care for pediatric traumatic brain injury PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

2017 PedsCCM Evidence-Based Journal Club

278. Prognostic role of copeptin after traumatic brain injury: A systematic review and meta-analysis of observational studies. (Abstract)

Prognostic role of copeptin after traumatic brain injury: A systematic review and meta-analysis of observational studies. Copeptin, the C-terminal portion of provasopressin, has emerged as a novel prognostic marker in neurocritical care, such as in traumatic brain injury (TBI). The aim of this study was to quantitatively assess the prognostic significance of initial plasma copeptin levels in the neurological outcome and mortality after traumatic brain injury.Six relevant studies with data from

2017 The American journal of emergency medicine

279. Complementary and alternative interventions for fatigue management after traumatic brain injury: a systematic review. (Full text)

Complementary and alternative interventions for fatigue management after traumatic brain injury: a systematic review. We systematically reviewed randomized controlled trials (RCTs) of complementary and alternative interventions for fatigue after traumatic brain injury (TBI).We searched multiple online sources including ClinicalTrials.gov, the Cochrane Library database, MEDLINE, CINAHL, Embase, the Web of Science, AMED, PsychINFO, Toxline, ProQuest Digital Dissertations, PEDro, PsycBite

2017 Therapeutic advances in neurological disorders PubMed abstract

280. Beta-Blockers and Traumatic Brain Injury: A Systematic Review, Meta-analysis, and Eastern Association for the Surgery of Trauma Guideline. (Full text)

Beta-Blockers and Traumatic Brain Injury: A Systematic Review, Meta-analysis, and Eastern Association for the Surgery of Trauma Guideline. To determine if beta-(β)-blockers improve outcomes after acute traumatic brain injury (TBI).There have been no new inpatient pharmacologic therapies to improve TBI outcomes in a half-century. Treatment of TBI patients with β-blockers offers a potentially beneficial approach.Using MEDLINE, EMBASE, and CENTRAL databases, eligible articles for our systematic

2017 Annals of Surgery PubMed abstract