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Latest & greatest articles for tramadol
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on tramadol or other clinical topics then use Trip today.
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Tramadol for osteoarthritis. BACKGROUND: Tramadol is increasingly used for the treatment of osteoarthritis because, in contrast to nonsteroidal anti-inflammatory drugs (NSAIDs), tramadol does not produce gastrointestinal bleeding or renal problems, and does not affect articular cartilage. OBJECTIVES: We sought to determine the analgesic effectiveness, the effect on physical function, the duration of benefit and the safety of oral tramadol in people with osteoarthritis. SEARCH STRATEGY: We (...) searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE and LILACS databases up to August 2005. SELECTION CRITERIA: We included randomized controlled trials (RCTs) that evaluated the effect of tramadol or tramadol plus paracetamol on pain levels and/or physical function in people with osteoarthritis. No language restriction was applied. DATA COLLECTION AND ANALYSIS: We analyzed separately placebo-controlled and active-controlled studies. We used fixed-effect models
Single-patient data meta-analysis of 3453 postoperative patients: oral tramadol versus placebo, codeine and combination analgesics Single-patient data meta-analysis of 3453 postoperative patients: oral tramadol versus placebo, codeine and combination analgesics Single-patient data meta-analysis of 3453 postoperative patients: oral tramadol versus placebo, codeine and combination analgesics Moore R A, McQuay H J Authors' objectives To assess the safety and effectiveness of oral tramadol (...) . Searching The trials were made available by Grunenthal GmbH (Aachen, Germany) and the Robert Wood Johnson Pharmaceutical Research Institute, (Pennsylvania, USA). In addition, the in-house database of Searle UK was searched, as were MEDLINE (from 1960 to 1995) and the Oxford Pain Relief Database (from 1950 to 1995)(see Other Publications of Related Interest no.1). 'Tramadol' was used as a free text term. Study selection Study designs of evaluations included in the review The review included individual