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Top results for testosterone

81. Testosterone supplementation therapy for older men: potential benefits and risks

Testosterone supplementation therapy for older men: potential benefits and risks Testosterone supplementation therapy for older men: potential benefits and risks Testosterone supplementation therapy for older men: potential benefits and risks Gruenewald D A, Matsumoto A M CRD summary This review assessed the effects of testosterone supplementation for men older than 60 without severe illness. The authors concluded that supplementation may be helpful for men with low testosterone levels (...) with or without hypogonadism. The review found only a few studies and the stated inclusion criteria were not consistently followed; hence, the conclusions should be interpreted with caution. Authors' objectives To assess the effect of testosterone supplementation therapy in older men. Searching MEDLINE was searched from 1966 to October 2001; the search terms were stated and reports published in any language were eligible. The reference lists of reviews and identified studies were checked. Manual searches

DARE.2003

82. Health related quality of life using serum testosterone as the trigger to re-dose long acting depot luteinizing hormone-releasing hormone agonists in patients with prostate cancer

Health related quality of life using serum testosterone as the trigger to re-dose long acting depot luteinizing hormone-releasing hormone agonists in patients with prostate cancer Health related quality of life using serum testosterone as the trigger to re-dose long acting depot luteinizing hormone-releasing hormone agonists in patients with prostate cancer Health related quality of life using serum testosterone as the trigger to re-dose long acting depot luteinizing (...) prostate cancer was examined. In addition, re-dosing LH-RH on the basis of serum testosterone was evaluated. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population The study population comprised patients who had a histological diagnosis of prostate cancer and elected androgen suppression therapy. Patients were not enrolled if they reported self-administering PC-SPES. Setting The setting was tertiary care. The economic analysis was conducted in the Department

NHS Economic Evaluation Database.2003

84. Testosterone therapy in HIV wasting syndrome: a systematic review and meta-analysis

Testosterone therapy in HIV wasting syndrome: a systematic review and meta-analysis Testosterone therapy in HIV wasting syndrome: a systematic review and meta-analysis Testosterone therapy in HIV wasting syndrome: a systematic review and meta-analysis Kong A, Edmonds P Authors' objectives To assess the effect of testosterone compared with placebo on lean-body mass, fat-free mass or body cell mass in human immunodeficiency virus (HIV)-positive people with wasting. Searching MEDLINE, EMBASE (...) 12 weeks were eligible for inclusion. All of the included RCTs were double-blind. Specific interventions included in the review Comparisons of any type of testosterone therapy (synthetic or nonsynthetic) with placebo were eligible for inclusion. Testosterone could be given using any mode of administration, including oral, patches or intramuscular (i.m.) injection. Studies that used resistance exercise in combination with testosterone were included. The included studies used oxandrolone (5 or 15

DARE.2002

85. Testosterone replacement in men with age-related hormone deficiency

Testosterone replacement in men with age-related hormone deficiency Testosterone replacement in men with age-related hormone deficiency We use cookies on this website. By using this site, you agree that we may store and access cookies on your device. Swedish Agency for Health Technology Assessment and Assessment of Social Services Testosterone replacement in men with age-related hormone deficiency Share: Reading time approx. 4 minutes This document was published more than 2 years ago (...) . The nature of the evidence may have changed. Findings by SBU Alert Version: 1 Technology and target group The production of male sex hormones (androgens) in the body declines with advancing age. Reduced levels may have negative effects on health. Therefore, androgen replacement has been tested on a smaller scale by administering testosterone, the most important of the male sex hormones. Potential health benefits include an increase in bone density, increased muscle mass, greater libido, and enhanced well

Swedish Council on Technology Assessement2002

86. Liquorice consumption and salivary testosterone concentrations.

Liquorice consumption and salivary testosterone concentrations. Liquorice consumption has been shown to substantially reduce serum testosterone concentration. An explanation for this result was that the active component in liquorice (glycyrrhizic acid) interfered with 17 beta-hydroxysteroid deyhydrogenase, which has been shown in vitro to catalyse the conversion of androstenedione to testosterone. We twice attempted to replicate this effect of liquorice but could not. We identified differences

Lancet2001

87. Intramuscular testosterone esters and plasma lipids in hypogonadal men: a meta-analysis

Intramuscular testosterone esters and plasma lipids in hypogonadal men: a meta-analysis Intramuscular testosterone esters and plasma lipids in hypogonadal men: a meta-analysis Intramuscular testosterone esters and plasma lipids in hypogonadal men: a meta-analysis Whitsel E A, Boyko E J, Matsumoto A M, Anawalt B D, Siscovick D S Authors' objectives To determine whether intramuscular administration of testosterone esters to hypogonadal men is associated with changes in plasma lipids. Searching (...) in which pre-treatment measures were recorded on a single group of patients who later received a treatment, after which post-treatment measurements were recorded. Specific interventions included in the review Intramuscular testosterone ester. The dosage of testosterone ester ranged from 50 to 250 mg every 7 to 30 days, for a duration of 1 to 24 months. Participants included in the review Male patients with non-experimental hypogonadism. Outcomes assessed in the review Studies which reported pre

DARE.2001

88. Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels.

Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels. 10683055 2000 02 29 2000 02 29 2016 12 08 0098-7484 283 6 2000 Feb 09 JAMA JAMA Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels. 763-70 Previous studies of testosterone supplementation in HIV-infected men failed to demonstrate improvement in muscle strength. The effects of resistance exercise combined (...) with testosterone supplementation in HIV-infected men are unknown. To determine the effects of testosterone replacement with and without resistance exercise on muscle strength and body composition in HIV-infected men with low testosterone levels and weight loss. Placebo-controlled, double-blind, randomized clinical trial conducted from September 1995 to July 1998 at a general clinical research center. Sixty-one HIV-infected men aged 18 to 50 years with serum testosterone levels of less than 12.1 nmol/L (349 ng

JAMA2000 Full Text: Link to full Text with Trip Pro

89. Oral androstenedione administration and serum testosterone concentrations in young men.

Oral androstenedione administration and serum testosterone concentrations in young men. 10683057 2000 02 29 2000 02 29 2016 10 17 0098-7484 283 6 2000 Feb 09 JAMA JAMA Oral androstenedione administration and serum testosterone concentrations in young men. 779-82 Androstenedione, a steroid hormone and the major precursor to testosterone, is available without prescription and is purported to increase strength and athletic performance. The hormonal effects of androstenedione, however, are unknown (...) . To determine if oral administration of androstenedione increases serum testosterone levels in healthy men. Open-label randomized controlled trial conducted between October 1998 and April 1999. General clinical research center of a tertiary-care, university-affiliated hospital. Forty-two healthy men aged 20 to 40 years. Subjects were randomized to receive oral androstenedione (either 100 mg/d [n = 15] or 300 mg/d [n = 14]) or no androstenedione (n = 13) for 7 days. Changes in serum testosterone

JAMA2000

90. Transdermal testosterone treatment in women with impaired sexual function after oophorectomy.

Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. 10974131 2000 09 07 2000 09 07 2013 11 21 0028-4793 343 10 2000 Sep 07 The New England journal of medicine N. Engl. J. Med. Transdermal testosterone treatment in women with impaired sexual function after oophorectomy. 682-8 The ovaries provide approximately half the circulating testosterone in premenopausal women. After bilateral oophorectomy, many women report impaired sexual functioning despite (...) estrogen replacement. We evaluated the effects of transdermal testosterone in women who had impaired sexual function after surgically induced menopause. Seventy-five women, 31 to 56 years old, who had undergone oophorectomy and hysterectomy received conjugated equine estrogens (at least 0.625 mg per day orally) and, in random order, placebo, 150 microg of testosterone, and 300 microg of testosterone per day transdermally for 12 weeks each. Outcome measures included scores on the Brief Index of Sexual

NEJM2000

91. Effect of oral androstenedione on serum testosterone and adaptations to resistance training in young men: a randomized controlled trial.

Effect of oral androstenedione on serum testosterone and adaptations to resistance training in young men: a randomized controlled trial. 10359391 1999 06 15 1999 06 15 2016 10 17 0098-7484 281 21 1999 Jun 02 JAMA JAMA Effect of oral androstenedione on serum testosterone and adaptations to resistance training in young men: a randomized controlled trial. 2020-8 Androstenedione, a precursor to testosterone, is marketed to increase blood testosterone concentrations as a natural alternative (...) to anabolic steroid use. However, whether androstenedione actually increases blood testosterone levels or produces anabolic androgenic effects is not known. To determine if short- and long-term oral androstenedione supplementation in men increases serum testosterone levels and skeletal muscle fiber size and strength and to examine its effect on blood lipids and markers of liver function. Eight-week randomized controlled trial conducted between February and June 1998. Thirty healthy, normotestosterogenic

JAMA1999

92. The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men.

The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men. 8637535 1996 07 11 1996 07 11 2013 11 21 0028-4793 335 1 1996 Jul 04 The New England journal of medicine N. Engl. J. Med. The effects of supraphysiologic doses of testosterone on muscle size and strength in normal men. 1-7 Athletes often take androgenic steroids in an attempt to increase their strength. The efficacy of these substances for this purpose is unsubstantiated, however. We randomly (...) assigned 43 normal men to one of four groups: placebo with no exercise; testosterone with no exercise; placebo plus exercise; and testosterone plus exercise. The men received injections of 600 mg of testosterone enanthate or placebo weekly for 10 weeks. The men in the exercise groups performed standardized weight-lifting exercises three times weekly. Before and after the treatment period, fat-free mass was determined by underwater weighing, muscle size was measured by magnetic resonance imaging

NEJM1996

93. Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome.

Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome. 8687515 1996 08 29 1996 08 29 2016 11 23 0028-4793 335 9 1996 Aug 29 The New England journal of medicine N. Engl. J. Med. Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome. 617-23 Insulin resistance and increased ovarian cytochrome P450c17 alpha (...) increased slightly in the placebo group. In the metformin group, the basal serum luteinizing hormone concentration decreased from 8.5 +/- 2.2 to 2.8 +/- 0.5 mlU per milliliter (P = 0.01), the serum free testosterone concentration decreased from 0.34 +/- 0.07 to 0.19 +/- 0.05 ng per deciliter (12 +/- 3 to 7 +/- 2 pmol per liter) (P = 0.009), and the serum sex hormone-binding globulin concentration increased from 0.8 +/- 0.2 to 2.3 +/- 0.6 microgram per deciliter (29 +/- 7 to 80 +/- 21 nmol per liter) (P

NEJM1996

94. Effect of oestrogen and testosterone implants on psychological disorders in the climacteric.

Effect of oestrogen and testosterone implants on psychological disorders in the climacteric. 2880114 1987 03 12 1987 03 12 2015 06 16 0140-6736 1 8528 1987 Feb 07 Lancet (London, England) Lancet Effect of oestrogen and testosterone implants on psychological disorders in the climacteric. 297-9 In a double-blind trial oestradiol, oestradiol/testosterone, or placebo implants were assessed for their effects on psychological symptoms in women attending a menopause clinic. After two months, women (...) Drug Implants 3XMK78S47O Testosterone 4TI98Z838E Estradiol AIM IM Adult Climacteric psychology Clinical Trials as Topic Depressive Disorder drug therapy Double-Blind Method Drug Implants Estradiol administration & dosage therapeutic use Female Humans Neurotic Disorders drug therapy Psychological Tests Testosterone administration & dosage therapeutic use 1987 2 7 1987 2 7 0 1 1987 2 7 0 0 ppublish 2880114 S0140-6736(87)92026-5

Lancet1987