Latest & greatest articles for surgery

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on surgery or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on surgery and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for surgery

81. Listening to music reduces pain and anxiety for patients having surgery

Listening to music reduces pain and anxiety for patients having surgery Signal - Listening to music reduces pain and anxiety for patients having surgery Dissemination Centre Discover Portal NIHR DC Discover Listening to music reduces pain and anxiety for patients having surgery Published on 28 October 2015 This systematic review found that music can moderately reduce pain and anxiety when played before, during or after surgery. It also strongly increased patient satisfaction. Music was equally (...) effective whether chosen by the patient or not. It was most effective when played before surgery and when the patient was conscious, though it was still effective even when played to the patient under general anaesthetic. Playing music may improve outcomes and patient satisfaction at no or marginal cost to the NHS. The agreement of the patient and the surgical team are advised, as it may not be suitable in all settings and the choice of music genre may not please all team members. Share your views

NIHR Dissemination Centre2018

82. Prophylactic platelet transfusions prior to surgery for people with a low platelet count.

Prophylactic platelet transfusions prior to surgery for people with a low platelet count. BACKGROUND: People with thrombocytopenia often require a surgical procedure. A low platelet count is a relative contraindication to surgery due to the risk of bleeding. Platelet transfusions are used in clinical practice to prevent and treat bleeding in people with thrombocytopenia. Current practice in many countries is to correct thrombocytopenia with platelet transfusions prior to surgery. Alternatives (...) to platelet transfusion are also used prior surgery. OBJECTIVES: To determine the clinical effectiveness and safety of prophylactic platelet transfusions prior to surgery for people with a low platelet count. SEARCH METHODS: We searched the following major data bases: Cochrane Central Register of Controlled Trials (CENTRAL; 2017, Issue 2), PubMed (e-publications only), Ovid MEDLINE, Ovid Embase, the Transfusion Evidence Library and ongoing trial databases to 11 December 2017. SELECTION CRITERIA: We

Cochrane2018

83. Patient-Controlled Paravertebral Block for Video-Assisted Thoracic Surgery: A Randomized Trial

Patient-Controlled Paravertebral Block for Video-Assisted Thoracic Surgery: A Randomized Trial 29763594 2018 08 24 1552-6259 106 3 2018 Sep The Annals of thoracic surgery Ann. Thorac. Surg. Patient-Controlled Paravertebral Block for Video-Assisted Thoracic Surgery: A Randomized Trial. 888-894 S0003-4975(18)30665-9 10.1016/j.athoracsur.2018.04.036 Paravertebral block (PVB) has been proven to be an efficient way to control postoperative pain in patients who have undergone a thoracotomy (...) . This study explored whether the use of a patient-controlled PVB can provide benefits over intravenous patient-controlled analgesia (PCA) for 3-port single-intercostal video-assisted thoracic surgery. From May 2015 to December 2016, patients who had solitary pulmonary nodules or spontaneous pneumothorax and underwent single-intercostal video-assisted thoracic surgery were randomly allocated to receive patient-controlled PVB or intravenous PCA. Intramuscular dezocine (10 mg) was used as a rescue medication

EvidenceUpdates2018

84. Preoperative Epoetin-alpha with Intravenous or Oral Iron for Major Orthopedic Surgery: A Randomized Controlled Trial

Preoperative Epoetin-alpha with Intravenous or Oral Iron for Major Orthopedic Surgery: A Randomized Controlled Trial 30074935 2018 08 03 1528-1175 2018 Aug 03 Anesthesiology Anesthesiology Preoperative Epoetin-α with Intravenous or Oral Iron for Major Orthopedic Surgery: A Randomized Controlled Trial. 10.1097/ALN.0000000000002376 WHAT THIS ARTICLE TELLS US THAT IS NEW: BACKGROUND:: Preoperative administration of epoetin-α with iron is commonly used in anemic patients undergoing major orthopedic (...) surgery, but the optimal route of iron intake is controversial. The aim of this study was to compare the clinical effects of erythropoietin in combination with oral or intravenous iron supplementation. This study was a prospective, randomized, single-blinded, parallel arm trial. Patients scheduled for elective hip or knee arthroplasty with hemoglobin 10 to 13 g/dl received preoperative injections of erythropoietin with oral ferrous sulfate or intravenous ferric carboxymaltose. The primary endpoint

EvidenceUpdates2018

85. Intravenously Administered Lidocaine and Magnesium During Thyroid Surgery in Female Patients for Better Quality of Recovery After Anesthesia

Intravenously Administered Lidocaine and Magnesium During Thyroid Surgery in Female Patients for Better Quality of Recovery After Anesthesia 29324495 2018 08 16 1526-7598 127 3 2018 Sep Anesthesia and analgesia Anesth. Analg. Intravenously Administered Lidocaine and Magnesium During Thyroid Surgery in Female Patients for Better Quality of Recovery After Anesthesia. 635-641 10.1213/ANE.0000000000002797 Although systemic lidocaine and magnesium have been widely studied as perioperative analgesic

EvidenceUpdates2018

86. The effectiveness of extended care based on Internet and home care platform for orthopaedics after hip replacement surgery in China

The effectiveness of extended care based on Internet and home care platform for orthopaedics after hip replacement surgery in China 29851157 2018 08 01 1365-2702 2018 May 31 Journal of clinical nursing J Clin Nurs The effectiveness of extended care based on Internet and home care platform for orthopaedics after hip replacement surgery in China. 10.1111/jocn.14545 To evaluate the effect of an Internet-based home orthopaedic care platform on patients' functional joint recovery, quality

EvidenceUpdates2018

87. Oral thyroxin supplementation in infants undergoing cardiac surgery: A double-blind placebo-controlled randomized clinical trial

Oral thyroxin supplementation in infants undergoing cardiac surgery: A double-blind placebo-controlled randomized clinical trial 30119284 2018 08 18 1097-685X 156 3 2018 Sep The Journal of thoracic and cardiovascular surgery J. Thorac. Cardiovasc. Surg. Oral thyroxin supplementation in infants undergoing cardiac surgery: A double-blind placebo-controlled randomized clinical trial. 1209-1217.e3 S0022-5223(18)31466-1 10.1016/j.jtcvs.2018.05.044 Decreases in serum total thyroxin and total (...) triiodothyronine occurs after cardiopulmonary bypass, and is reflected as poor immediate outcome. We studied effects of oral thyroxin supplementation in infants who underwent open-heart surgery. In this prospective study, 100 patients were randomized into 2 groups: 50 in the thyroxin group (TH) and 50 in the placebo group (PL). Patients in the TH group received oral thyroxin (5 μg/kg) 12 hours before surgery and once daily for the remainder of their intensive care unit (ICU) stay. Data on intraoperative

EvidenceUpdates2018

88. Frailty as a Predictor of Death or New Disability After Surgery: A Prospective Cohort Study

Frailty as a Predictor of Death or New Disability After Surgery: A Prospective Cohort Study 30048320 2018 07 26 1528-1140 2018 Jul 24 Annals of surgery Ann. Surg. Frailty as a Predictor of Death or New Disability After Surgery: A Prospective Cohort Study. 10.1097/SLA.0000000000002967 To compare the accuracy of the modified Fried Index (mFI) and the Clinical Frailty Scale (CFS) to predict death or patient-reported new disability 90 days after major elective surgery. The association of frailty (...) with patient-reported outcomes, and comparisons between preoperative frailty instruments are poorly described. This was a prospective multicenter cohort study. We determined frailty status in individuals ≥65 years having elective noncardiac surgery using the mFI and CFS. Outcomes included death or patient-reported new disability (primary); safety incidents, length of stay (LOS), and institutional discharge (secondary); ease of use, usefulness, benefit, clinical importance, and feasibility (tertiary). We

EvidenceUpdates2018

89. Mortality effects of timing alternatives for hip fracture surgery

Mortality effects of timing alternatives for hip fracture surgery 30087128 2018 08 14 1488-2329 190 31 2018 Aug 07 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Mortality effects of timing alternatives for hip fracture surgery. E923-E932 10.1503/cmaj.171512 The appropriate timing of hip fracture surgery remains a matter of debate. We sought to estimate the effect of changes in timing policy and the proportion of deaths attributable to surgical (...) delay. We obtained discharge abstracts from the Canadian Institute for Health Information for hip fracture surgery in Canada (excluding Quebec) between 2004 and 2012. We estimated the expected population-average risks of inpatient death within 30 days if patients were surgically treated on day of admission, inpatient day 2, day 3 or after day 3. We weighted observations with the inverse propensity score of surgical timing according to confounders selected from a causal diagram. Of 139 119 medically

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

90. Restrictive compared with liberal red cell transfusion strategies in cardiac surgery: a meta-analysis

Restrictive compared with liberal red cell transfusion strategies in cardiac surgery: a meta-analysis 30107514 2018 08 14 1522-9645 2018 Aug 10 European heart journal Eur. Heart J. Restrictive compared with liberal red cell transfusion strategies in cardiac surgery: a meta-analysis. 10.1093/eurheartj/ehy435 To determine whether a restrictive strategy of red blood cell (RBC) transfusion at lower haemoglobin concentrations is inferior to a liberal strategy of RBC transfusion at higher haemoglobin (...) concentrations in patients undergoing cardiac surgery. We conducted a systematic review, meta-analysis, and trial sequential analysis of randomized controlled trials of the effect of restrictive and liberal RBC transfusion strategies on mortality within 30 days of surgery as the primary outcome. Secondary outcomes were those potentially resulting from anaemia-induced tissue hypoxia and transfusion outcomes. We searched the electronic databases MEDLINE, EMBASE, and the Cochrane Library until 17 November 2017

EvidenceUpdates2018

91. Predicting Likelihood of Surgery Before First Visit in Patients With Back and Lower Extremity Symptoms: A Simple Mathematical Model Based on More Than 8,000 Patients

Predicting Likelihood of Surgery Before First Visit in Patients With Back and Lower Extremity Symptoms: A Simple Mathematical Model Based on More Than 8,000 Patients 29432393 2018 08 28 1528-1159 43 18 2018 Sep 15 Spine Spine Predicting Likelihood of Surgery Before First Visit in Patients With Back and Lower Extremity Symptoms: A Simple Mathematical Model Based on More Than 8,000 Patients. 1296-1305 10.1097/BRS.0000000000002603 Retrospective analysis of prospectively collected data. To create (...) a data-driven triage system stratifying patients by likelihood of undergoing spinal surgery within 1 year of presentation. Low back pain (LBP) and radicular lower extremity (LE) symptoms are common musculoskeletal problems. There is currently no standard data-derived triage process based on information that can be obtained before the initial physician-patient encounter to direct patients to the optimal physician type. We analyzed patient-reported data from 8006 patients with a chief complaint of low

EvidenceUpdates2018

92. Association between age, deprivation and specific comorbid conditions and the receipt of major surgery in patients with non-small cell lung cancer in England: A population-based study

Association between age, deprivation and specific comorbid conditions and the receipt of major surgery in patients with non-small cell lung cancer in England: A population-based study 30100577 2018 08 13 1468-3296 2018 Aug 12 Thorax Thorax Association between age, deprivation and specific comorbid conditions and the receipt of major surgery in patients with non-small cell lung cancer in England: A population-based study. thoraxjnl-2017-211395 10.1136/thoraxjnl-2017-211395 We investigated (...) . To describe the association between prognostic factors and surgery, we performed two different analyses: one using multivariable logistic regression and one estimating cause-specific hazards for death and surgery. In both analyses, we used multiple imputation to deal with missing data. We showed strong evidence that the comorbidities 'congestive heart failure', 'cerebrovascular disease' and 'chronic obstructive pulmonary disease' reduced the receipt of surgery in early stage patients. We also observed

EvidenceUpdates2018

93. The Use of Adjunct Psychosocial Interventions Can Decrease Postoperative Pain and Improve the Quality of Clinical Care in Orthopedic Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

The Use of Adjunct Psychosocial Interventions Can Decrease Postoperative Pain and Improve the Quality of Clinical Care in Orthopedic Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials 29803669 2018 08 18 1528-8447 2018 May 25 The journal of pain : official journal of the American Pain Society J Pain The Use of Adjunct Psychosocial Interventions Can Decrease Postoperative Pain and Improve the Quality of Clinical Care in Orthopedic Surgery: A Systematic Review and Meta (...) -Analysis of Randomized Controlled Trials. S1526-5900(18)30194-9 10.1016/j.jpain.2018.05.006 This study aims to assess the effectiveness of psychosocial techniques to decrease postoperative pain and improve perioperative clinical care in orthopedic surgery. A systematic review and meta-analysis was performed to evaluate the effects of psychosocial methods among adults undergoing orthopedic surgeries. The systematic review included both randomized and nonrandomized trials, but only randomized controlled

EvidenceUpdates2018

94. The Perioperative Efficacy and Safety of Antifibrinolytics in Adult Spinal Fusion Surgery: A Systematic Review and Meta-analysis

The Perioperative Efficacy and Safety of Antifibrinolytics in Adult Spinal Fusion Surgery: A Systematic Review and Meta-analysis 30063223 2018 07 31 1528-1159 43 16 2018 Aug Spine Spine The Perioperative Efficacy and Safety of Antifibrinolytics in Adult Spinal Fusion Surgery: A Systematic Review and Meta-analysis. E949-E958 10.1097/BRS.0000000000002580 Systematic review and meta-analysis. Compare outcomes of adult patients undergoing spinal fusion surgery who receive and do not receive (...) perioperative antifibrinolytics to reduce operative blood loss. The clinical potential for antifibrinolytics such as tranexamic acid and epsilon aminocaproic acid to significantly reduce blood loss during adult spinal fusion surgery remains underexplored. Outcomes for assessment included operative blood loss, and other surgical, clinical, and haematological outcomes. We followed the recommended Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines for systematic reviews

EvidenceUpdates2018

95. Enhanced Recovery After Surgery (ERAS) in gynecologic oncology: System-wide implementation and audit leads to improved value and patient outcomes

Enhanced Recovery After Surgery (ERAS) in gynecologic oncology: System-wide implementation and audit leads to improved value and patient outcomes Institute of Health Economics | Toggle navigation MENU / Advanced Search Enhanced Recovery After Surgery (ERAS) in gynecologic oncology: System-wide implementation and audit leads to improved value and patient outcomes August 08, 2018 The Institute of Health Economics has contributed to a study published in the Journal Gynecologic Oncology. The study (...) described the effects of Enhanced Recovery After Surgery (ERAS) guideline implementation in gynecologic oncology on length of stay, patient outcomes, and economic impact in Alberta. The study compared pre-and post-guideline implementation outcomes at two centers that provide the majority of surgical gynecologic oncology care in Alberta, Canada between March 2016 and April 2017. Results showed median length of stay for all surgeries decreased from 4.0 days to 3.0 days for medium/high complexity surgery

Institute of Health Economics2018

96. Three-Dimensional Versus Two-Dimensional Video-Assisted Endoscopic Surgery: A Meta-analysis of Clinical Data

Three-Dimensional Versus Two-Dimensional Video-Assisted Endoscopic Surgery: A Meta-analysis of Clinical Data 29946785 2018 06 27 1432-2323 2018 Jun 26 World journal of surgery World J Surg Three-Dimensional Versus Two-Dimensional Video-Assisted Endoscopic Surgery: A Meta-analysis of Clinical Data. 10.1007/s00268-018-4681-z There have been no studies to systematically evaluate the two display (3D vs. 2D) systems regarding both laparoscopic and thoracoscopic surgeries in clinical settings; thus (...) , we conducted one to evaluate the safety and efficacy of different visualization systems (two-dimensional and three-dimensional) during endoscopic surgery (laparoscopy or thoracoscopy) in clinical settings. A comprehensive search of online databases was performed. Perioperative outcomes were synthesized. Cumulative meta-analysis was performed to evaluate the temporal trend of pooled outcomes. Specific subgroups (laparoscopy vs. thoracoscopy, prospective vs. retrospective study, malignant vs

EvidenceUpdates2018

97. Effects of Nutritional Prehabilitation, With and Without Exercise, on Outcomes of Patients Who Undergo Colorectal Surgery: A Systematic Review and Meta-analysis

Effects of Nutritional Prehabilitation, With and Without Exercise, on Outcomes of Patients Who Undergo Colorectal Surgery: A Systematic Review and Meta-analysis 29750973 2018 08 13 2018 08 13 1528-0012 155 2 2018 08 Gastroenterology Gastroenterology Effects of Nutritional Prehabilitation, With and Without Exercise, on Outcomes of Patients Who Undergo Colorectal Surgery: A Systematic Review and Meta-analysis. 391-410.e4 S0016-5085(18)34530-X 10.1053/j.gastro.2018.05.012 Although there have been (...) meta-analyses of the effects of exercise-only prehabilitation on patients undergoing colorectal surgery, little is known about the effects of nutrition-only (oral nutritional supplements with and without counseling) and multimodal (oral nutritional supplements with and without counseling and with exercise) prehabilitation on clinical outcomes and patient function after surgery. We performed a systemic review and meta-analysis to determine the individual and combined effects of nutrition-only

EvidenceUpdates2018

98. Effect of aspirin in vascular surgery in patients from a randomized clinical trial (POISE-2)

Effect of aspirin in vascular surgery in patients from a randomized clinical trial (POISE-2) 30019751 2018 07 18 1365-2168 2018 Jul 18 The British journal of surgery Br J Surg Effect of aspirin in vascular surgery in patients from a randomized clinical trial (POISE-2). 10.1002/bjs.10925 In the POISE-2 (PeriOperative ISchemic Evaluation 2) trial, perioperative aspirin did not reduce cardiovascular events, but increased major bleeding. There remains uncertainty regarding the effect (...) of perioperative aspirin in patients undergoing vascular surgery. The aim of this substudy was to determine whether there is a subgroup effect of initiating or continuing aspirin in patients undergoing vascular surgery. POISE-2 was a blinded, randomized trial of patients having non-cardiac surgery. Patients were assigned to perioperative aspirin or placebo. The primary outcome was a composite of death or myocardial infarction at 30 days. Secondary outcomes included: vascular occlusive complications

EvidenceUpdates2018

99. Quadratus Lumborum Block Versus Perioperative Intravenous Lidocaine for Postoperative Pain Control in Patients Undergoing Laparoscopic Colorectal Surgery: A Prospective, Randomized, Double-blind Controlled Clinical Trial

Quadratus Lumborum Block Versus Perioperative Intravenous Lidocaine for Postoperative Pain Control in Patients Undergoing Laparoscopic Colorectal Surgery: A Prospective, Randomized, Double-blind Controlled Clinical Trial 30004914 2018 07 18 1528-1140 2018 Jul 12 Annals of surgery Ann. Surg. Quadratus Lumborum Block Versus Perioperative Intravenous Lidocaine for Postoperative Pain Control in Patients Undergoing Laparoscopic Colorectal Surgery: A Prospective, Randomized, Double-blind Controlled (...) Clinical Trial. 10.1097/SLA.0000000000002888 To investigate the comparative analgesic efficacy of systemic lidocaine and quadratus lumborum (QL) block in laparoscopic colorectal surgery. Although epidural analgesia is the standard to control pain in patients undergoing open colorectal surgery, optimal analgesic management in laparoscopic surgery is less well-defined. There is need for effective and efficient alternatives to epidural analgesia for pain management in patients undergoing laparoscopic

EvidenceUpdates2018

100. Prognostic value of the Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification in patients with no-option chronic limb-threatening ischemia

Prognostic value of the Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification in patients with no-option chronic limb-threatening ischemia 29802042 2018 05 26 1097-6809 2018 May 22 Journal of vascular surgery J. Vasc. Surg. Prognostic value of the Society for Vascular Surgery Wound, Ischemia, and foot Infection (WIfI) classification in patients with no-option chronic limb-threatening ischemia. S0741-5214(18)30422-1 10.1016/j.jvs.2018.02.028 The Wound, Ischemia (...) pain, without wounds or infection (W0-I3-fI0), when they lack revascularization options. Further studies are needed to determine whether reassignment of this population from WIfI stage 2 to WIfI stage 3 may be appropriate to reflect amputation risk in the absence of successful revascularization for patients suffering from ischemic rest pain in general. Copyright © 2018 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved. van Haelst Steven T W STW Department of Vascular

EvidenceUpdates2018