Latest & greatest articles for stroke

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Top results for stroke

1. Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in people with stroke or transient ischaemic attack. (PubMed)

Peroxisome proliferator-activated receptor gamma agonists for preventing recurrent stroke and other vascular events in people with stroke or transient ischaemic attack. Peroxisome proliferator-activated receptor gamma (PPAR-γ) agonists are insulin-sensitising drugs used for the treatment of insulin resistance. In addition to lowering glucose in diabetes, these drugs may also protect against hyperlipidaemia and arteriosclerosis, which are risk factors for stroke. This is an update of a review (...) first published in January 2014 and subsequently updated in December 2017.To assess the efficacy and safety of PPAR-γ agonists in the secondary prevention of stroke and related vascular events for people with stroke or transient ischaemic attack (TIA).We searched the Cochrane Stroke Group Trials Register (30 July 2019), the Cochrane Central Register of Controlled Trials (CENTRAL; 2019, Issue 7), MEDLINE (1949 to 30 July 2019), Embase (1980 to 30 July 2019), CINAHL (1982 to 30 July 2019), AMED (1985

2019 Cochrane

2. Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults. (PubMed)

Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults. To estimate the risk of acute myocardial infarction (AMI) or stroke in adults with non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).Matched cohort study.Population based, electronic primary healthcare databases before 31 December 2015 from four European countries: Italy (n=1 542 672), Netherlands (n=2 (...)  225 925), Spain (n=5 488 397), and UK (n=12 695 046).120 795 adults with a recorded diagnosis of NAFLD or NASH and no other liver diseases, matched at time of NAFLD diagnosis (index date) by age, sex, practice site, and visit, recorded at six months before or after the date of diagnosis, with up to 100 patients without NAFLD or NASH in the same database.Primary outcome was incident fatal or non-fatal AMI and ischaemic or unspecified stroke. Hazard ratios were estimated using Cox models and pooled

2019 BMJ

3. Interventions for preventing falls in people after stroke. (PubMed)

Interventions for preventing falls in people after stroke. Falls are one of the most common complications after stroke, with a reported incidence ranging between 7% in the first week and 73% in the first year post stroke. This is an updated version of the original Cochrane Review published in 2013.To evaluate the effectiveness of interventions aimed at preventing falls in people after stroke. Our primary objective was to determine the effect of interventions on the rate of falls (number (...) of falls per person-year) and the number of fallers. Our secondary objectives were to determine the effects of interventions aimed at preventing falls on 1) the number of fall-related fractures; 2) the number of fall-related hospital admissions; 3) near-fall events; 4) economic evaluation; 5) quality of life; and 6) adverse effects of the interventions.We searched the trials registers of the Cochrane Stroke Group (September 2018) and the Cochrane Bone, Joint and Muscle Trauma Group (October 2018

2019 Cochrane

4. Portable Stroke Diagnosis Devices for Adults with Stroke Symptoms: A Review of Diagnostic Accuracy and Cost-Effectiveness

Portable Stroke Diagnosis Devices for Adults with Stroke Symptoms: A Review of Diagnostic Accuracy and Cost-Effectiveness Portable Stroke Diagnosis Devices for Adults with Stroke Symptoms: A Review of Diagnostic Accuracy and Cost-Effectiveness | CADTH.ca Find the information you need Portable Stroke Diagnosis Devices for Adults with Stroke Symptoms: A Review of Diagnostic Accuracy and Cost-Effectiveness Portable Stroke Diagnosis Devices for Adults with Stroke Symptoms: A Review of Diagnostic (...) Accuracy and Cost-Effectiveness Last updated: July 2, 2019 Project Number: RC1151-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the diagnostic accuracy of portable stroke diagnostic devices for adults with stroke symptoms? What is the cost-effectiveness of portable stroke diagnostic devices for adults with stroke symptoms? Key Message One relevant non-randomized study was identified regarding diagnostic accuracy

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

5. Portable Stroke Diagnosis Devices for Adults with Stroke Symptoms: Diagnostic Accuracy and Cost-Effectiveness

Portable Stroke Diagnosis Devices for Adults with Stroke Symptoms: Diagnostic Accuracy and Cost-Effectiveness Portable Stroke Diagnosis Devices for Adults with Stroke Symptoms: Diagnostic Accuracy and Cost-Effectiveness | CADTH.ca Find the information you need Portable Stroke Diagnosis Devices for Adults with Stroke Symptoms: Diagnostic Accuracy and Cost-Effectiveness Portable Stroke Diagnosis Devices for Adults with Stroke Symptoms: Diagnostic Accuracy and Cost-Effectiveness Last updated: June (...) 17, 2019 Project Number: RA1042-000 Product Line: Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What is the diagnostic accuracy of portable stroke diagnostic devices for adults with stroke symptoms? What is the cost-effectiveness of portable stroke diagnostic devices for adults with stroke symptoms? Key Message One non-randomized study was identified regarding the diagnostic accuracy of portable stroke diagnostic devices for adults with stroke

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

6. Association of General Anesthesia vs Procedural Sedation With Functional Outcome Among Patients With Acute Ischemic Stroke Undergoing Thrombectomy: A Systematic Review and Meta-analysis. (PubMed)

Association of General Anesthesia vs Procedural Sedation With Functional Outcome Among Patients With Acute Ischemic Stroke Undergoing Thrombectomy: A Systematic Review and Meta-analysis. General anesthesia during thrombectomy for acute ischemic stroke has been associated with poor neurological outcome in nonrandomized studies. Three single-center randomized trials reported no significantly different or improved outcomes for patients who received general anesthesia compared with procedural (...) sedation.To detect differences in functional outcome at 3 months between patients who received general anesthesia vs procedural sedation during thrombectomy for anterior circulation acute ischemic stroke.MEDLINE search for English-language articles published from January 1, 1980, to July 31, 2019.Randomized clinical trials of adults with a National Institutes of Health Stroke Scale score of at least 10 and anterior circulation acute ischemic stroke assigned to receive general anesthesia or procedural

2019 JAMA

7. Stroke, Diagnosis and Initial Treatment of Ischemic Stroke

Stroke, Diagnosis and Initial Treatment of Ischemic Stroke Health Care Guideline: Diagnosis and Initial Treatment of Ischemic Stroke www.icsi.org Acute Ischemic Stroke Algorithm Copyright © 2019 by Institute for Clinical Systems Improvement 1 Twelfth Edition June 2019 Is patient a candidate for endovascular thrombectomy? Initial assessment includes: Exam, vitals, O 2 (oxygen), record weight, assess severity using NIHSS Monitor Labs: 1) Glucose 2) INR/Cr/CBC – if there is no suspicion (...) that these are abnormal, do not delay head CT or IV Alteplase Unless emergently indicated, do not delay imaging/IV Alteplase to obtain EKG, CXR or place foley Patient presents with signs and symptoms of an acute stroke Manage hemorrhagic stroke Positive for hemorrhage Evaluate for TIA Negative for hemorrhage (resolved neurological de?cits) Symptom onset? Negative for hemorrhage (continuing neurological de?cits) Neurology consultation Within 4.5 hours > 4.5 hours or time of onset is unknown IV Alteplase

2019 Institute for Clinical Systems Improvement

8. Sex Differences in Long-Term Quality of Life Among Survivors After Stroke in the INSTRUCT

Sex Differences in Long-Term Quality of Life Among Survivors After Stroke in the INSTRUCT Background and Purpose- Women are reported to have poorer health-related quality of life (HRQoL) after stroke than men, but the underlying reasons are uncertain. We investigated factors contributing to the sex differences. Methods- Individual participant data on 4288 first-ever strokes (1996-2013) were obtained from 4 high-quality population-based incidence studies from Australasia and Europe. HRQoL (...) utility scores among survivors after stroke (range from negative scores=worse than death to 1=perfect health) were calculated from 3 scales including European Quality of Life-5 Dimensions, Short-Form 6-Dimension, and Assessment of Quality of Life at 1 year (3 studies; n=1210) and 5 years (3 studies; n=1057). Quantile regression was used to estimate the median differences in HRQoL for women compared to men with adjustment for covariates. Study factors included sociodemographics, prestroke dependency

2019 EvidenceUpdates

9. Does Sex Modify the Effect of Endovascular Treatment for Ischemic Stroke?

Does Sex Modify the Effect of Endovascular Treatment for Ischemic Stroke? Background and Purpose- Previous studies have reported less favorable outcome and less effect of endovascular treatment (EVT) after ischemic stroke in women than in men. Our aim was to study the influence of sex on outcome and on the effect of EVT for ischemic stroke in recent randomized trials on EVT. Methods- We used data from 7 randomized controlled trials on EVT within the HERMES collaboration. The primary outcome

2019 EvidenceUpdates

10. Clinical Guidelines for Stroke Management

Clinical Guidelines for Stroke Management InformMe - Clinical Guidelines for Stroke Management Our websites {{ user.firstName }} {{ user.lastName }} Go back {{ user.firstName }} {{ user.lastName }} Where am I? Clinical Guidelines for Stroke Management The Clinical Guidelines for Stroke Management are evolving into , updated as new evidence emerges in accordance with the 2011 NHMRC Standard for clinical practice guidelines. They supersede the Clinical Guidelines for Stroke Management 2017 (...) of stroke care, across 8 chapters: Imaging Cardiac investigations Thrombolysis Neurointervention Medical interventions Surgical interventions Smoking Diet Physical activity Obesity Alcohol Weakness Loss of sensation Vision Amount of rehabilitation Cardiorespiratory fitness Sitting Standing up Standing balance Walking Upper limb activity Assessment of communication deficits Aphasia Dysarthria Apraxia of speech Cognitive communication disorder in right hemisphere stroke Assessment of cognition Executive

2019 Stroke Foundation - Australia

11. Portable Stroke Detection Devices for Patients with Stroke Symptoms: A Review of Diagnostic Accuracy and Cost-Effectiveness

Portable Stroke Detection Devices for Patients with Stroke Symptoms: A Review of Diagnostic Accuracy and Cost-Effectiveness Portable Stroke Detection Devices for Patients with Stroke Symptoms: A Review of Diagnostic Accuracy and Cost-Effectiveness | CADTH.ca Find the information you need Portable Stroke Detection Devices for Patients with Stroke Symptoms: A Review of Diagnostic Accuracy and Cost-Effectiveness Portable Stroke Detection Devices for Patients with Stroke Symptoms: A Review (...) of Diagnostic Accuracy and Cost-Effectiveness Last updated: August 7, 2019 Project Number: RC1167-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the diagnostic accuracy of portable stroke detection devices for patients with stroke symptoms? What is the cost-effectiveness of portable stroke diagnostic devices for patients with stroke symptoms? Key Message No relevant literature was identified regarding the diagnostic

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

12. Behavioural activation therapy for post-stroke depression: the BEADS feasibility RCT

Behavioural activation therapy for post-stroke depression: the BEADS feasibility RCT Behavioural activation therapy for post-stroke depression: the BEADS feasibility RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue

2019 NIHR HTA programme

13. Do Calcium Antagonists Decrease Mortality or Dependency in Acute Ischemic Stroke?

Do Calcium Antagonists Decrease Mortality or Dependency in Acute Ischemic Stroke? Do Calcium Antagonists Decrease Mortality or Dependency in Acute Ischemic Stroke? - Annals of Emergency Medicine Email/Username: Password: Remember me Search Terms Search within Search Share this page Access provided by Volume 74, Issue 4, Pages 575–577 Do Calcium Antagonists Decrease Mortality or Dependency in Acute Ischemic Stroke? x Rachel E. Bridwell , MD (EBEM Commentator) , x Brit Long , MD (EBEM Commentator (...) ) , x Michael D. April , MD, DPhil (EBEM Commentator) Department of Emergency Medicine, San Antonio Uniformed Services Health Education Consortium, Fort Sam Houston, TX DOI: | Publication History Published online: May 09, 2019 Expand all Collapse all Article Outline Take-Home Message The use of calcium antagonists in acute ischemic stroke does not reduce mortality or dependency in activities of daily living. Methods Data Sources An information specialist searched the Cochrane Stroke Group Trials

2019 Annals of Emergency Medicine Systematic Review Snapshots

14. Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study. (PubMed)

Perioperative covert stroke in patients undergoing non-cardiac surgery (NeuroVISION): a prospective cohort study. In non-surgical settings, covert stroke is more common than overt stroke and is associated with cognitive decline. Although overt stroke occurs in less than 1% of adults after non-cardiac surgery and is associated with substantial morbidity, we know little about perioperative covert stroke. Therefore, our primary aim was to investigate the relationship between perioperative covert (...) stroke (ie, an acute brain infarct detected on an MRI after non-cardiac surgery in a patient with no clinical stroke symptoms) and cognitive decline 1 year after surgery.NeuroVISION was a prospective cohort study done in 12 academic centres in nine countries, in which we assessed patients aged 65 years or older who underwent inpatient, elective, non-cardiac surgery and had brain MRI after surgery. Two independent neuroradiology experts, masked to clinical data, assessed each MRI for acute brain

2019 Lancet

15. Physical Fitness Training in Patients with Subacute Stroke (PHYS-STROKE): multicentre, randomised controlled, endpoint blinded trial. (PubMed)

Physical Fitness Training in Patients with Subacute Stroke (PHYS-STROKE): multicentre, randomised controlled, endpoint blinded trial. To determine the safety and efficacy of aerobic exercise on activities of daily living in the subacute phase after stroke.Multicentre, randomised controlled, endpoint blinded trial.Seven inpatient rehabilitation sites in Germany (2013-17).200 adults with subacute stroke (days 5-45 after stroke) with a median National Institutes of Health stroke scale (NIHSS (...) , range 0-42 points, higher values indicating more severe strokes) score of 8 (interquartile range 5-12) were randomly assigned (1:1) to aerobic physical fitness training (n=105) or relaxation sessions (n=95, control group) in addition to standard care.Participants received either aerobic, bodyweight supported, treadmill based physical fitness training or relaxation sessions, each for 25 minutes, five times weekly for four weeks, in addition to standard rehabilitation therapy. Investigators

2019 BMJ

16. Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study. (PubMed)

Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study. To examine the associations of vegetarianism with risks of ischaemic heart disease and stroke.Prospective cohort study.The EPIC-Oxford study, a cohort in the United Kingdom with a large proportion of non-meat eaters, recruited across the country between 1993 and 2001.48 188 participants with no history of ischaemic heart disease (...) , stroke, or angina (or cardiovascular disease) were classified into three distinct diet groups: meat eaters (participants who consumed meat, regardless of whether they consumed fish, dairy, or eggs; n=24 428), fish eaters (consumed fish but no meat; n=7506), and vegetarians including vegans (n=16 254), based on dietary information collected at baseline, and subsequently around 2010 (n=28 364).Incident cases of ischaemic heart disease and stroke (including ischaemic and haemorrhagic types) identified

2019 BMJ

17. Society of Interventional Radiology Training Guidelines for Endovascular Stroke Treatment (Full text)

Society of Interventional Radiology Training Guidelines for Endovascular Stroke Treatment Society of Interventional Radiology Training Guidelines for Endovascular Stroke Treatment - Journal of Vascular and Interventional Radiology Email/Username: Password: Remember me Available now: Use your SIR login to access JVIR. Search Terms Search within Search Share this page Access provided by Volume 30, Issue 10, Pages 1523–1531 Society of Interventional Radiology Training Guidelines for Endovascular (...) Stroke Treatment x David Sacks Affiliations Department of Interventional Radiology, The Reading Hospital and Medical Center, West Reading, Pennsylvania Correspondence Address correspondence to D.S., c/o Elizabeth Himes, 3975 Fair Ridge Dr., Suite 400 N., Fairfax, VA 22033 , MD a , ∗ , x David Sacks Affiliations Department of Interventional Radiology, The Reading Hospital and Medical Center, West Reading, Pennsylvania Correspondence Address correspondence to D.S., c/o Elizabeth Himes, 3975 Fair Ridge

2019 Society of Interventional Radiology PubMed

18. Management of Stroke Rehabilitation

Management of Stroke Rehabilitation VA/DoD CLINICAL PRACTICE GUIDELINE FOR THE MANAGEMENT OF STROKE REHABILITATION Department of Veterans Affairs Department of Defense QUALIFYING STATEMENTS The Department of Veterans Affairs and the Department of Defense guidelines are based upon the best information available at the time of publication. They are designed to provide information and assist decision making. They are not intended to define a standard of care and should not be construed as one (...) and/or therapeutic interventions within these guidelines does not guarantee coverage of civilian sector care. Additional information on current TRICARE benefits may be found at www.tricare.mil or by contacting your regional TRICARE Managed Care Support Contractor. Version 4.0 – 2019VA/DoD Clinical Practice Guideline for the Management of Stroke Rehabilitation July 2019 Page 2 of 170 Prepared by: The Management of Stroke Rehabilitation Work Group With support from: The Office of Quality, Safety and Value, VA

2019 VA/DoD Clinical Practice Guidelines

19. Organisation of the early management of acute ischaemic stroke using mechanical thrombectomy

Organisation of the early management of acute ischaemic stroke using mechanical thrombectomy Organisation of the early management of acute ischaemic stroke using mechanical thrombectomy - Technological assessment report

2019 Haute Autorite de sante

20. Vertebral artery stenting to prevent recurrent stroke in symptomatic vertebral artery stenosis: the VIST RCT

Vertebral artery stenting to prevent recurrent stroke in symptomatic vertebral artery stenosis: the VIST RCT Vertebral artery stenting to prevent recurrent stroke in symptomatic vertebral artery stenosis: the VIST RCT Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you (...) need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> 1)"> {{metadata.Title}} {{metadata.Headline}} This trial did not recruit the planned number of patients or show that vertebral stenting reduced the risk of stroke. {{author}} {{($index , , , , , , & . Hugh S Markus 1, * , Susanna C Larsson 1 , John Dennis 2 , Wilhelm Kuker 3 , Ursula G Schulz 3 , Ian Ford 4 , Andrew Clifton 5, † , Peter M Rothwell 3, † 1 Stroke Research Group, Department of Clinical Neurosciences, University

2019 NIHR HTA programme