Latest & greatest articles for side effects

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Top results for side effects

141. Metabolic side effects of atypical antipsychotics in children: a literature review

Metabolic side effects of atypical antipsychotics in children: a literature review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2005 DARE.

142. Oral methadone for chronic noncancer pain: a systematic literature review of reasons for administration, prescription patterns, effectiveness, and side effects

Oral methadone for chronic noncancer pain: a systematic literature review of reasons for administration, prescription patterns, effectiveness, and side effects Oral methadone for chronic noncancer pain: a systematic literature review of reasons for administration, prescription patterns, effectiveness, and side effects Oral methadone for chronic noncancer pain: a systematic literature review of reasons for administration, prescription patterns, effectiveness, and side effects Sandoval J (...) A, Furlan A D, Mailis-Gagnon A CRD summary This review assessed the indications, prescription, effectiveness and side-effects of oral methadone for the treatment of chronic non-cancer pain. The authors concluded that the use of oral methadone is based on uncontrolled studies and further research is needed. This review was generally well conducted and its conclusions can be considered reliable, although the effectiveness results may be overrated. Authors' objectives To assess the indications

2005 DARE.

143. Effects of nonsteroidal antiinflammatory drugs on patient-controlled analgesia morphine side effects: meta-analysis of randomized controlled trials

Effects of nonsteroidal antiinflammatory drugs on patient-controlled analgesia morphine side effects: meta-analysis of randomized controlled trials Effects of nonsteroidal antiinflammatory drugs on patient-controlled analgesia morphine side effects: meta-analysis of randomized controlled trials Effects of nonsteroidal antiinflammatory drugs on patient-controlled analgesia morphine side effects: meta-analysis of randomized controlled trials Marret E, Kurdi O, Zufferey P, Bonnet F CRD summary (...) of review methods. Other aspects of the review were well conducted and the authors' conclusions are likely to be reliable. Implications of the review for practice and research The authors did not state any implications for practice or further research. Bibliographic details Marret E, Kurdi O, Zufferey P, Bonnet F. Effects of nonsteroidal antiinflammatory drugs on patient-controlled analgesia morphine side effects: meta-analysis of randomized controlled trials. Anesthesiology 2005; 102(6): 1249-1260

2005 DARE.

144. Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials

Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2005 DARE.

145. Review: new generation antipsychotics do not induce fewer extrapyramidal side effects than low potency antipsychotics Full Text available with Trip Pro

Review: new generation antipsychotics do not induce fewer extrapyramidal side effects than low potency antipsychotics Review: new generation antipsychotics do not induce fewer extrapyramidal side effects than low potency antipsychotics | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: new generation antipsychotics do not induce fewer extrapyramidal side effects than low potency antipsychotics Article Text Therapeutics Review

2004 Evidence-Based Medicine

146. Finasteride reduced prostate cancer but led to more high grade tumours and sexual side effects Full Text available with Trip Pro

Finasteride reduced prostate cancer but led to more high grade tumours and sexual side effects Finasteride reduced prostate cancer but led to more high grade tumours and sexual side effects | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Finasteride reduced prostate cancer but led to more high grade tumours and sexual side effects Article Text Therapeutics Finasteride reduced prostate cancer but led to more high grade tumours

2004 Evidence-Based Medicine

147. Review: drugs do not improve symptoms in urinary urge incontinence and may have side effects Full Text available with Trip Pro

Review: drugs do not improve symptoms in urinary urge incontinence and may have side effects Review: drugs do not improve symptoms in urinary urge incontinence and may have side effects | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: drugs do not improve symptoms in urinary urge incontinence and may have side effects Article Text Therapeutics Review: drugs do not improve symptoms in urinary urge incontinence and may have

2004 Evidence-Based Medicine

148. Selenoprotein synthesis and side-effects of statins. (Abstract)

Selenoprotein synthesis and side-effects of statins. Statins are possibly the most effective drugs for the prevention and treatment of hypercholesterolaemia and coronary heart disease. They are generally well tolerated, however, they do cause some unusual side-effects with potentially severe consequences, most prominently myopathy or rhabdomyolysis and polyneuropathy. We noted that the pattern of side-effects associated with statins resembles the pathology of selenium deficiency, and postulated (...) that the mechanism lay in a well established, but often overlooked, biochemical pathway--the isopentenylation of selenocysteine-tRNA([Ser]Sec). A negative effect of statins on selenoprotein synthesis does seem to explain many of the enigmatic effects and side-effects of statins, in particular, statin-induced myopathy.

2004 Lancet

149. Impact of side-effects of atypical antipsychotics on non-compliance, relapse and cost

Impact of side-effects of atypical antipsychotics on non-compliance, relapse and cost Impact of side-effects of atypical antipsychotics on non-compliance, relapse and cost Impact of side-effects of atypical antipsychotics on non-compliance, relapse and cost Mortimer A, Williams P, Meddis D Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions (...) outcomes was derived from a review of published studies and reviews. It was supplemented by a two-round Delphi study, in which a panel of 25 experts on schizophrenia assessed the impact of different side effect profiles on non-compliance. Modelling A state-transition model was used to represent the relationship between compliance and relapse over a 1-year period following recovery from an episode of schizophrenia. This technique involved identifying clinically important events and defining them

2003 NHS Economic Evaluation Database.

150. Ephedra and ephedrine for weight loss and athletic performance enhancement: clinical efficacy and side effects

Ephedra and ephedrine for weight loss and athletic performance enhancement: clinical efficacy and side effects Ephedra and ephedrine for weight loss and athletic performance enhancement: clinical efficacy and side effects Ephedra and ephedrine for weight loss and athletic performance enhancement: clinical efficacy and side effects Shekelle P, Morton S, Maglione M, Hardy M, Suttorp M, Roth E, Jungvig L, Mojica WA, Gagne J, Rhodes S, McKinnon E CRD summary This review assessed the effectiveness (...) and safety of using ephedrine or ephedra for weight loss or improving athletic performance. The authors concluded that ephedra and ephedrine provide modest, short-term improvements in weight loss, but that they are associated with increased rates of side-effects. These conclusions reflected the limited evidence available and are likely to be reliable. Authors' objectives To assess the efficacy and safety of ephedra and ephedrine on weight loss and athletic performance. Searching MEDLINE, EMBASE, BIOSIS

2003 DARE.

151. The efficacy of behavioral interventions for cancer treatment-related side effects

The efficacy of behavioral interventions for cancer treatment-related side effects The efficacy of behavioral interventions for cancer treatment-related side effects The efficacy of behavioral interventions for cancer treatment-related side effects Mundy E A, DuHamel K N, Montgomery G H CRD summary This review found that behavioural interventions could reduce anticipatory nausea and vomiting in people undergoing chemotherapy and decrease anxiety related to cancer diagnosis and treatment (...) for studies published in English. The search terms were reported. Study selection Study designs of evaluations included in the review Published randomised controlled trials (RCTs), within-subject cohort studies and case reports were eligible for inclusion. Review articles and sub-samples of data from larger studies were excluded. Specific interventions included in the review Studies were eligible for inclusion in the review if they assessed a behavioural intervention for side-effects related to cancer

2003 DARE.

152. Management of opioid side effects in cancer-related and chronic noncancer pain: a systematic review

Management of opioid side effects in cancer-related and chronic noncancer pain: a systematic review Management of opioid side effects in cancer-related and chronic noncancer pain: a systematic review Management of opioid side effects in cancer-related and chronic noncancer pain: a systematic review McNicol E, Horowicz-Mehler N, Fisk R A, Bennett K, Gialeli-Goudas M, Chew P W, Lau J, Carr D CRD summary The authors concluded that they found limited evidence to support diverse interventions (...) for the management of opioid-related side-effects, as well as the general approach of opioid rotation, and that there is a need for higher quality research. These conclusions appear justified on the basis of the evidence reported in the review, though it is possible that relevant evidence may have been available that was not included in the review. Authors' objectives To assess the management of opioid side-effects in the context of cancer pain management or, in the event that no evidence was available

2003 DARE.

153. Ephedra and ephedrine for weight loss and athletic performance enhancement: clinical efficacy and side effects

Ephedra and ephedrine for weight loss and athletic performance enhancement: clinical efficacy and side effects Ephedra and ephedrine for weight loss and athletic performance enhancement: clinical efficacy and side effects Ephedra and ephedrine for weight loss and athletic performance enhancement: clinical efficacy and side effects Shekelle P, Morton S, Maglione M Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation (...) of the quality of this assessment has been made for the HTA database. Citation Shekelle P, Morton S, Maglione M. Ephedra and ephedrine for weight loss and athletic performance enhancement: clinical efficacy and side effects. Rockville: Agency for Healthcare Research and Quality (AHRQ). Evidence Report/Technology Assessment No. 76. 2003 Authors' objectives This report aims to assess the efficacy of herbal ephedra-containing dietary supplements and ephedrine on weight loss and athletic performance, through

2003 Health Technology Assessment (HTA) Database.

154. Provision of information about drug side-effects to patients. (Abstract)

Provision of information about drug side-effects to patients. To make informed decisions about taking medicinal drugs, people need accurate information about side-effects. A European Union guideline now recommends use of qualitative descriptions for five bands of risk, ranging from very rare (affecting <0.01% of the population), to very common (>10%). We did four studies of more than 750 people, whom we asked to estimate the probability of having a side-effect on the basis of qualitative

2002 Lancet

155. Nonspecific medication side effects and the nocebo phenomenon. (Abstract)

Nonspecific medication side effects and the nocebo phenomenon. Patients taking active medications frequently experience adverse, nonspecific side effects that are not a direct result of the specific pharmacological action of the drug. Although this phenomenon is common, distressing, and costly, it is rarely studied and poorly understood. The nocebo phenomenon, in which placebos produce adverse side effects, offers some insight into nonspecific side effect reporting. We performed a focused (...) review of the literature, which identified several factors that appear to be associated with the nocebo phenomenon and/or reporting of nonspecific side effects while taking active medication: the patient's expectations of adverse effects at the outset of treatment; a process of conditioning in which the patient learns from prior experiences to associate medication-taking with somatic symptoms; certain psychological characteristics such as anxiety, depression, and the tendency to somatize

2002 JAMA

156. Is sensorineural hearing loss a possible side effect of nasopharyngeal and parotid irradiation: a systematic review of the literature

Is sensorineural hearing loss a possible side effect of nasopharyngeal and parotid irradiation: a systematic review of the literature Is sensorineural hearing loss a possible side effect of nasopharyngeal and parotid irradiation: a systematic review of the literature Is sensorineural hearing loss a possible side effect of nasopharyngeal and parotid irradiation: a systematic review of the literature Raaijmakers E, Engelen A M Authors' objectives The authors appear to study the effects (...) . Is sensorineural hearing loss a possible side effect of nasopharyngeal and parotid irradiation: a systematic review of the literature. Radiotherapy and Oncology 2002; 65(1): 1-7 PubMedID Indexing Status Subject indexing assigned by NLM MeSH Hearing /radiation effects; Hearing Loss, Sensorineural /etiology; Humans; Nasopharyngeal Neoplasms /radiotherapy; Parotid Neoplasms /radiotherapy; Radiation Injuries /etiology AccessionNumber 12003000015 Date bibliographic record published 28/02/2005 Date abstract record

2002 DARE.

157. Meta-analysis of effects and side effects of low dosage tricyclic antidepressants in depression: systematic review. Full Text available with Trip Pro

Meta-analysis of effects and side effects of low dosage tricyclic antidepressants in depression: systematic review. To compare the effects and side effects of low dosage tricyclic antidepressants with placebo and with standard dosage tricyclics in acute phase treatment of depression.Systematic review of randomised trials comparing low dosage tricyclics (< or =100 mg/day) with placebo or with standard dosage tricyclics in adults with depression.Relative risk of response in depression (random (...) effects model), according to the original authors' definition but usually defined as 50% or greater reduction in severity of depression. Relative risks of overall dropouts and dropouts due to side effects.35 studies (2013 participants) compared low dosage tricyclics with placebo, and six studies (551 participants) compared low dosage tricyclics with standard dosage tricyclics. Low dosage tricyclics, mostly between 75 and 100 mg/day, were 1.65 (95% confidence interval 1.36 to 2.0) and 1.47 (1.12

2002 BMJ

158. Behavioral intervention for cancer treatment side effects

Behavioral intervention for cancer treatment side effects Behavioral intervention for cancer treatment side effects Behavioral intervention for cancer treatment side effects Redd W H, Montgomery G H, DuHamel K N Authors' objectives To evaluate the clinical impact of behavioural interventions in patients undergoing cancer treatment. Searching PubMed and PsycLIT were searched from 1979 to January 2000 for reports published in the English language, using the following search terms in combination (...) patients). Nausea and vomiting (23 studies, including 13 RCTs with 401 patients). Studies supported the effectiveness of behavioural interventions in controlling anticipatory nausea and vomiting. Twelve of the 13 RCTs reported a statistically-significant benefit from behavioural interventions when compared with a no treatment or attention control interventions. Modest results were found in the 4 studies that assessed behavioural interventions in post-chemotherapy side-effects. Anxiety and distress (19

2001 DARE.

159. The cost effectiveness of self-expanding metal stents in the management of malignant left-sided large bowel obstruction Full Text available with Trip Pro

The cost effectiveness of self-expanding metal stents in the management of malignant left-sided large bowel obstruction The cost effectiveness of self-expanding metal stents in the management of malignant left-sided large bowel obstruction The cost effectiveness of self-expanding metal stents in the management of malignant left-sided large bowel obstruction HS Osman, HI Rashid, N Sathananthan, MC Parker Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The study evaluated the cost-effectiveness of self-expanding metal stents to treat acute left-sided large bowel obstruction in colorectal carcinoma. The authors concluded that stenting showed reduction in hospital stay and costs, but further analysis was necessary due to small sample size

2000 NHS Economic Evaluation Database.

160. Umbilical artery catheters in the newborn: effects of catheter design (end vs side hole). (Abstract)

Umbilical artery catheters in the newborn: effects of catheter design (end vs side hole). This section is under preparation and will be included in the next issue.To determine whether the design of an umbilical arterial catheter influences the frequency of ischemic events, aortic thrombosis, intraventricular hemorrhage, mortality or necrotising enterocolitis in newborn infants.Randomized and quasi randomized controlled trials of umbilical catheterization use were obtained from the following (...) sources: 1. Effective Care of the Newborn Infant, edited by JC Sinclair and MB Bracken. 2. Medline Search using Melvyl Medline Plus and the keyword headings 'Umbilic#', 'Catheter#' and subject heading 'Infant, Newborn' 3. Search of personal data filesRandomized trials in newborn infants of any birthweight or gestation. Comparison of end hole catheters with side hole catheters. Clinically important end points such as ischemic events or aortic thrombosis.There appears to be only a single trial which has

2000 Cochrane