Latest & greatest articles for side effects

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This page lists the very latest high quality evidence on side effects and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for side effects

1. Inducing labour mechanically can be as effective as the recommended drugs and may have fewer side effects

Inducing labour mechanically can be as effective as the recommended drugs and may have fewer side effects Signal - Inducing labour mechanically can be as effective as the recommended drugs and may have fewer side effects Dissemination Centre Discover Portal NIHR DC Discover Inducing labour mechanically can be as effective as the recommended drugs and may have fewer side effects Published on 8 November 2016 Double-balloon catheters seem to be as effective as vaginal prostaglandin drugs (...) for inducing labour, while also avoiding overstimulation of the womb. The catheter is a device inserted through the cervix, where inflated balloons put pressure on the cervix helping it to “ripen” and start contractions. Prostaglandin drugs are the current recommended induction method, but uterine (womb) overstimulation, where contractions become too frequent or long, is a recognised side effect. This trial found that with either method half of women went on to a vaginal delivery within 24 hours

NIHR Dissemination Centre2018

2. Fewer side-effects and similar benefits from shorter chemotherapy after bowel cancer surgery

Fewer side-effects and similar benefits from shorter chemotherapy after bowel cancer surgery Fewer side-effects and similar benefits from shorter chemotherapy after bowel cancer surgery Dissemination Centre Discover Portal NIHR DC Discover Fewer side-effects and similar benefits from shorter chemotherapy after bowel cancer surgery Published on 12 June 2018 A three-month course of chemotherapy after surgery for bowel cancer seems no less effective than the standard six-month course, and half (...) as many people suffered from nerve damage as a side-effect. Three-quarters of people survived to three years without disease progression on either treatment. This international trial, part funded by the NIHR, included over 6,000 people with high-risk stage II or III bowel cancer that had spread through the bowel wall or to nearby lymph nodes. Standard treatment after surgery is usually six months of an oxaliplatin-containing regimen. This study evaluated a shorter course. Oxaliplatin is known

NIHR Dissemination Centre2018

3. Adverse side effects of dexamethasone in surgical patients.

Adverse side effects of dexamethasone in surgical patients. BACKGROUND: In the perioperative period, dexamethasone is widely and effectively used for prophylaxis of postoperative nausea and vomiting (PONV), for pain management, and to facilitate early discharge after ambulatory surgery.Long-term treatment with steroids has many side effects, such as adrenal insufficiency, increased infection risk, hyperglycaemia, high blood pressure, osteoporosis, and development of diabetes mellitus. However (...) , whether a single steroid load during surgery has negative effects during the postoperative period has not yet been studied. OBJECTIVES: To assess the effects of a steroid load of dexamethasone on postoperative systemic or wound infection, delayed wound healing, and blood glucose change in adult surgical patients (with planned subgroup analysis of patients with and without diabetes). SEARCH METHODS: We searched MEDLINE, Embase, the Cochrane Central Register of Controlled Trials (CENTRAL

Cochrane2018

4. Safety and Side Effects of Rifampin versus Isoniazid in Children.

Safety and Side Effects of Rifampin versus Isoniazid in Children. BACKGROUND: The treatment of latent infection with Mycobacterium tuberculosis is important in children because of their vulnerability to life-threatening forms of tuberculosis disease. The current standard treatment - 9 months of isoniazid - has been associated with poor adherence and toxic effects, which have hampered the effectiveness of the drug. In adults, treatment with 4 months of rifampin has been shown to be safer (...) and to have higher completion rates than 9 months of isoniazid. METHODS: In this multicenter, open-label trial, we randomly assigned 844 children (<18 years of age) with latent M. tuberculosis infection to receive either 4 months of rifampin or 9 months of isoniazid. The primary outcome was adverse events of grade 1 to 5 that resulted in the permanent discontinuation of a trial drug. Secondary outcomes were treatment adherence, side-effect profile, and efficacy. Independent review panels whose members

NEJM2018

5. Side effects

Side effects Top results for side effects - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing (...) the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for side effects The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines

Trip Latest and Greatest2018

6. Slow Infusion of Low-dose Ketamine Reduces Bothersome Side Effects Compared to Intravenous Push: A Double-blind, Double-dummy, Randomized Controlled Trial

Slow Infusion of Low-dose Ketamine Reduces Bothersome Side Effects Compared to Intravenous Push: A Double-blind, Double-dummy, Randomized Controlled Trial 29645317 2018 05 25 1553-2712 2018 Apr 12 Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med Slow Infusion of Low-dose Ketamine Reduces Bothersome Side Effects Compared to Intravenous Push: A Double-blind, Double-dummy, Randomized Controlled Trial. 10.1111/acem.13428 We compared (...) the analgesic efficacy and incidence of side effects when low-dose (0.3 mg/kg) ketamine (LDK) is administered as a slow infusion (SI) over 15 minutes versus an intravenous push (IVP) over 1 minute. This was a prospective, randomized, double-blind, double-dummy, placebo-controlled trial of adult ED patients presenting with moderate to severe pain (numerical rating scale [NRS] score ≥ 5). Patients received 0.3 mg/kg ketamine administered either as a SI or a IVP. Our primary outcome was the proportion

EvidenceUpdates2018

7. Inducing labour mechanically can be as effective as the recommended drugs and may have fewer side effects

Inducing labour mechanically can be as effective as the recommended drugs and may have fewer side effects NIHR DC | Signal - Inducing labour mechanically can be as effective as the recommended drugs and may have fewer side effects Dissemination Centre Discover Portal NIHR DC Discover NIHR Signal Inducing labour mechanically can be as effective as the recommended drugs and may have fewer side effects Published on 8 November 2016 Double-balloon catheters seem to be as effective as vaginal (...) prostaglandin drugs for inducing labour, while also avoiding overstimulation of the womb. The catheter is a device inserted through the cervix, where inflated balloons put pressure on the cervix helping it to “ripen” and start contractions. Prostaglandin drugs are the current recommended induction method, but uterine (womb) overstimulation, where contractions become too frequent or long, is a recognised side effect. This trial found that with either method half of women went on to a vaginal delivery within

NIHR Dissemination Centre2018

8. Early and Late Onset Side Effects of Photodynamic Therapy

Early and Late Onset Side Effects of Photodynamic Therapy biomedicines Review Early and Late Onset Side Effects of Photodynamic Therapy Francesco Borgia *, Roberta Giuffrida, Emanuela Caradonna, Mario Vaccaro ID , Fabrizio Guarneri and Sera?nella P . Cannavò Section of Dermatology—Department of Clinical and Experimental Medicine, University of Messina, 98125 Messina, Italy; robgiuffrida@unime.it (R.G.); emanuela.caradonna79@gmail.com (E.C.); mario.vaccaro@unime.it (M.V .); f.guarneri@tiscali.it (...) (F.G.); patrizia.cannavo@unime.it (S.P .C.) * Correspondence: fborgia@unime.it; Tel.: +39-347-9143476 Received: 31 December 2017; Accepted: 25 January 2018; Published: 29 January 2018 Abstract: Photodynamic Therapy (PDT) is a non-invasive treatment successfully used for neoplastic, in?ammatory and infectious skin diseases. One of its strengths is represented by the high safety pro?le, even in elderly and/or immuno-depressed subjects. PDT, however, may induce early and late onset side effects

Biomedicines2018 Full Text: Link to full Text with Trip Pro

9. e-cigarettes and refill containers (e-liquids): report suspected side effects and safety concerns

e-cigarettes and refill containers (e-liquids): report suspected side effects and safety concerns e-cigarettes and refill containers (e-liquids): report suspected side effects and safety concerns - GOV.UK GOV.UK uses cookies to make the site simpler. Search e-cigarettes and refill containers (e-liquids): report suspected side effects and safety concerns From: Published: 21 June 2017 Use the Yellow Card Reporting Scheme to support the safety of e-cigarettes and refill containers (e-liquids (...) ). Contents What and how to report Members of the public and healthcare professionals can use the to report any suspected side effects or safety concerns with e-cigarettes and the e-liquids used for vaping. These issues could include: • suspected side-effects that occurred after the use of e-cigarettes and e-liquids • harm to children or non-users, including accidental poisoning • safety issues or defects with e-cigarette devices Your information will aid us in identifying previously unrecognised side

MHRA Drug Safety Update2017

10. [How to evaluate side effects in a clinical trial?]

[How to evaluate side effects in a clinical trial?] 28236990 2017 02 26 2017 02 26 0013-7006 42 6S 2016 Dec L'Encephale Encephale [How to evaluate side effects in a clinical trial?] S30-S32 S0013-7006(17)30051-9 10.1016/S0013-7006(17)30051-9 Adverse effects of psychotropic medications must be systematically assessed during a clinical trial. This systematic and mandatory evaluation, for the patient safety first, will also allow to establish for the tested molecule, an efficiency/tolerance ratio (...) which could be compared to preexisting medications, and guide the clinician prescriptions. These side effects are closely related to the pharmacological profile of the tested molecule, in particular its monoamine binding profile. Antipsychotics are taken as an example, with a focus on classical clinical side effects related to each monoamine transmission blocking. © L’Encéphale, Paris, 2016. Maurel M M SHU Psychiatrie Adultes, Hôpital Sainte Marguerite, 13274 Marseille Cedex 9, France. Electronic

L'Encephale2017

11. Evidence of ocular side effects of SSRIs and new warnings

Evidence of ocular side effects of SSRIs and new warnings Evidence of ocular side effects of SSRIs and new warnings | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Evidence of ocular side effects of SSRIs and new warnings Article Text Outcomes Evidence of ocular side effects of SSRIs and new warnings Julia Kirkham , Dallas Seitz Statistics from Altmetric.com ABSTRACT FROM: Chen H , Lin C , Lai S , et al . Association of selective serotonin reuptake inhibitor use and acute angle-closure glaucoma . What is already known on this topic Acute angle

Evidence-Based Mental Health2017

12. Use of acupuncture to alleviate side effects in radiation oncology: Current evidence and future directions

Use of acupuncture to alleviate side effects in radiation oncology: Current evidence and future directions Redirecting

Advances in radiation oncology2016 Full Text: Link to full Text with Trip Pro

13. Apomorphine with domperidone: minimising risk of cardiac side effects

Apomorphine with domperidone: minimising risk of cardiac side effects Apomorphine with domperidone: minimising risk of cardiac side effects - GOV.UK GOV.UK uses cookies to make the site simpler. Search Apomorphine with domperidone: minimising risk of cardiac side effects From: Published: 18 April 2016 Therapeutic area: and Patients receiving apomorphine and domperidone require an assessment of cardiac risk factors and ECG monitoring to reduce the risk of serious arrhythmia related to QT (...) -prolongation. Contents Advice for healthcare professionals: Before starting treatment, carefully consider whether the benefits of concomitant apomorphine and domperidone treatment outweigh the small increased risk of cardiac side effects Discuss the benefits and risks of apomorphine with patients and carers and advise them to contact their doctor immediately if they develop palpitations or syncopal symptoms during treatment Check the QT-interval before starting domperidone, during the apomorphine

MHRA Drug Safety Update2016

14. Improving symptoms and side effects in older patients with schizophrenia with decreasing dopamine D2/3 receptor occupancy following risperidone and olanzapine dose reduction

Improving symptoms and side effects in older patients with schizophrenia with decreasing dopamine D2/3 receptor occupancy following risperidone and olanzapine dose reduction Improving symptoms and side effects in older patients with schizophrenia with decreasing dopamine D2/3 receptor occupancy following risperidone and olanzapine dose reduction | Evidence-Based Mental Health This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Improving symptoms and side effects in older patients with schizophrenia with decreasing dopamine D2/3 receptor occupancy following risperidone

Evidence-Based Mental Health2015

15. Effects of vertical and side-alternating vibration training on fall risk factors and bone turnover in older people at risk of falls

Effects of vertical and side-alternating vibration training on fall risk factors and bone turnover in older people at risk of falls 25294839 2014 12 05 2015 08 03 2015 11 19 1468-2834 44 1 2015 Jan Age and ageing Age Ageing Effects of vertical and side-alternating vibration training on fall risk factors and bone turnover in older people at risk of falls. 115-22 10.1093/ageing/afu136 whole-body vibration training may improve neuromuscular function, falls risk and bone density, but previous (...) studies have had conflicting findings. this study aimed to evaluate the influence of vertical vibration (VV) and side-alternating vibration (SV) on musculoskeletal health in older people at risk of falls. single-blind, randomised, controlled trial comparing vibration training to sham vibration (Sham) in addition to usual care. participants were 61 older people (37 women and 24 men), aged 80.2 + 6.5 years, referred to an outpatient falls prevention service. participants were randomly assigned to VV, SV

EvidenceUpdates2014

16. Ocular side effects following intravitreal injection therapy for retinoblastoma: a systematic review

Ocular side effects following intravitreal injection therapy for retinoblastoma: a systematic review Ocular side effects following intravitreal injection therapy for retinoblastoma: a systematic review Ocular side effects following intravitreal injection therapy for retinoblastoma: a systematic review Smith SJ, Smith BD, Mohney BG CRD summary This review concluded that significant ocular complications were uncommon following intravitreal injection therapy for retinoblastoma (malignant tumour (...) of the retina), and this risk may be reduced further by the use of careful injection technique and standard dosing regimens. These conclusions appear likely to be reliable, and the review recommendations for research are appropriate. Authors' objectives To describe the ocular side effects in patients receiving intravitreal injection therapy for retinoblastoma. Searching PubMed, Scopus, Science Citation Index, and Conference Proceedings Citation Index-Science were searched up to April 2013 with no language

DARE.2014

17. This asthma treatment has a lasting side effect in children

This asthma treatment has a lasting side effect in children This asthma treatment has a lasting side effect in children Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics This asthma treatment has a lasting side effect in children View/ Open Date 2013-09 Format Metadata Abstract Before prescribing inhaled corticosteroids (...) (ICS) for a child with asthma, tell the patient -- and parents -- that their use could lead to a small but permanent effect on adult height. Strength of recommendation: B: Based on one prospective study. URI Part of Citation Journal of Family Practice, 62(9) 2013: 500-502. Collections hosted by hosted by

PURLS2014

18. Statins have no side effects? What our study really found, its fixable flaws, and why trials transparency matters (again).

Statins have no side effects? What our study really found, its fixable flaws, and why trials transparency matters (again). Statins have no side effects? What our study really found, its fixable flaws, and why trials transparency matters (again). – Bad Science Search TED Talk Collected Journalism This Nerdy Book This Great Book T-shirts Categories (3) (4) (6) (45) (28) (6) (15) (190) (5) (20) (52) (88) (2) (1) (2) (1) (675) (4) (14) (2) (37) (4) (9) (3) (11) (6) (3) (16) (13) (1) (6) (8) (6) (6 (...) ) (12) (1) (59) (2) (6) (34) (26) (1) (1) (1) (2) (2) (1) (52) (7) (2) (1) (2) (3) (1) (1) (1) (4) (2) (82) (1) (10) (6) (3) (2) (1) (5) (1) (10) (1) (2) (1) (1) (6) (4) (3) (2) (52) (3) (18) (10) (1) March 13th, 2014 by Ben Goldacre in , , | Hi there, sorry to be absent (dayjob!). I was surprised to see a study I’m a co-author on getting some today, under the headline “Statins ‘have no side effects'”. That’s not what found. But it was an interesting piece of work, with an odd result, looking

Bad Science2014

19. Domperidone: risks of cardiac side effects

Domperidone: risks of cardiac side effects Domperidone: risks of cardiac side effects Drug Safety Update - GOV.UK GOV.UK uses cookies to make the site simpler. Search Domperidone: risks of cardiac side effects From: Published: 30 May 2014 Therapeutic area: and Indication restricted to nausea and vomiting, new contraindications, and reduced dose and duration of use. Article date: May 2014 Domperidone is a dopamine antagonist with antiemetic properties. A European review assessed the benefits (...) and risks of domperidone following continued reports of cardiac side effects. The review confirmed a small increased risk of serious cardiac side effects. A higher risk was observed particularly in people older than 60 years, people taking daily oral domperidone doses of more than 30 mg, and those taking QT-prolonging medicines or CYP3A4 inhibitors at the same time as domperidone. For indications other than nausea and vomiting, the benefits were not considered to outweigh the cardiac risk. Based

MHRA Drug Safety Update2014

20. Ivabradine (Procoralan) in the symptomatic treatment of angina: risk of cardiac side effects

Ivabradine (Procoralan) in the symptomatic treatment of angina: risk of cardiac side effects Ivabradine (Procoralan) in the symptomatic treatment of angina: risk of cardiac side effects Drug Safety Update - GOV.UK GOV.UK uses cookies to make the site simpler. Search Ivabradine (Procoralan) in the symptomatic treatment of angina: risk of cardiac side effects From: Published: 19 December 2014 Therapeutic area: New advice to minimise risk Ivabradine (Procoralan) is used to treat chronic heart

MHRA Drug Safety Update2014