Latest & greatest articles for sertraline

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Top results for sertraline

41. Similar effectiveness of paroxetine, fluoxetine, and sertraline in primary care: a randomized trial.

Similar effectiveness of paroxetine, fluoxetine, and sertraline in primary care: a randomized trial. 11743835 2001 12 17 2002 01 14 2016 10 17 0098-7484 286 23 2001 Dec 19 JAMA JAMA Similar effectiveness of paroxetine, fluoxetine, and sertraline in primary care: a randomized trial. 2947-55 Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed class of antidepressant, yet it is not known whether one SSRI is more effective than another. To compare the effectiveness of 3 (...) SSRIs (paroxetine, fluoxetine, and sertraline) in depressed primary care patients. Open-label, randomized, intention-to-treat trial, with patient enrollment occurring in April-November 1999. Thirty-seven clinics in 2 US primary care research networks. A total of 573 depressed adult patients for whom their primary care physician thought that antidepressant therapy was warranted and who completed a baseline interview. Patients were randomly assigned to receive paroxetine (n = 189), fluoxetine (n = 193

JAMA2001

42. Sertraline: a review of its therapeutic use in post-traumatic stress disorder

Sertraline: a review of its therapeutic use in post-traumatic stress disorder Sertraline: a review of its therapeutic use in post-traumatic stress disorder Sertraline: a review of its therapeutic use in post-traumatic stress disorder Comer A M, Figgitt D P Authors' objectives To review the clinical efficacy and tolerability of sertraline in post-traumatic stress disorder. Searching Adisbase, MEDLINE and EMBASE were searched from 1966 to October 2000 using the terms 'sertraline' or 'CP-51974 (...) ' or 'CP-5197401' and 'post-traumatic-stress-disorder' and 'sertraline adj pk/pd'. Additional references were identified from the reference lists of published articles. Bibliographical information, including contributory unpublished data, was also requested from the company developing the drug. Study selection Study designs of evaluations included in the review When available, large well-controlled trials with appropriate statistical methodology were preferred. Specific interventions included

DARE.2000

43. Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial.

Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial. 10770145 2000 04 27 2000 04 27 2016 10 17 0098-7484 283 14 2000 Apr 12 JAMA JAMA Efficacy and safety of sertraline treatment of posttraumatic stress disorder: a randomized controlled trial. 1837-44 Despite the high prevalence, chronicity, and associated comorbidity of posttraumatic stress disorder (PTSD) in the community, few placebo-controlled studies have evaluated the efficacy (...) of pharmacotherapy for this disorder. To determine if treatment with sertraline hydrochloride effectively diminishes symptoms of PTSD of moderate to marked severity. Twelve-week, double-blind, placebo-controlled trial preceded by a 2-week, single-blind placebo lead-in period, conducted between May 1996 and June 1997. Outpatient psychiatric clinics in 8 academic medical centers and 6 clinical research centers. A total of 187 outpatients with a Diagnostic and Statistical Manual of Mental Disorders, Revised Third

JAMA2000

44. Sertraline in children and adolescents with obsessive-compulsive disorder: a multicenter randomized controlled trial.

Sertraline in children and adolescents with obsessive-compulsive disorder: a multicenter randomized controlled trial. 9842950 1998 12 14 1998 12 14 2016 10 17 0098-7484 280 20 1998 Nov 25 JAMA JAMA Sertraline in children and adolescents with obsessive-compulsive disorder: a multicenter randomized controlled trial. 1752-6 The serotonin reuptake inhibitors are the treatment of choice for patients with obsessive-compulsive disorder; however, empirical support for this assertion has been weaker (...) for children and adolescents than for adults. To evaluate the safety and efficacy of the selective serotonin reuptake inhibitor sertraline hydrochloride in children and adolescents with obsessive-compulsive disorder. Randomized, double-blind, placebo-controlled trial. One hundred eighty-seven patients: 107 children aged 6 to 12 years and 80 adolescents aged 13 to 17 years randomized to receive either sertraline (53 children, 39 adolescents) or placebo (54 children, 41 adolescents). Twelve US academic

JAMA1998

45. Maintenance phase efficacy of sertraline for chronic depression: a randomized controlled trial.

Maintenance phase efficacy of sertraline for chronic depression: a randomized controlled trial. 9831997 1998 12 08 1998 12 08 2016 10 25 0098-7484 280 19 1998 Nov 18 JAMA JAMA Maintenance phase efficacy of sertraline for chronic depression: a randomized controlled trial. 1665-72 The chronic form of major depression is associated with a high rate of prevalence and disability, but no controlled research has examined the impact of long-term treatment on the course and burden of illness (...) . To determine if maintenance therapy with sertraline hydrochloride can effectively prevent recurrence of depression in the high-risk group of patients experiencing chronic major depression or major depression with antecedent dysthymic disorder ("double depression"). A 76-week randomized, double-blind, parallel-group study, conducted from September 1993 to November 1996. Outpatient psychiatric clinics at 10 academic medical centers and 2 clinical research centers. Maintenance treatment with either sertraline

JAMA1998

46. Symptomatic improvement of premenstrual dysphoric disorder with sertraline treatment. A randomized controlled trial. Sertraline Premenstrual Dysphoric Collaborative Study Group.

Symptomatic improvement of premenstrual dysphoric disorder with sertraline treatment. A randomized controlled trial. Sertraline Premenstrual Dysphoric Collaborative Study Group. 9307345 1997 10 08 1997 10 08 2016 10 17 0098-7484 278 12 1997 Sep 24 JAMA JAMA Symptomatic improvement of premenstrual dysphoric disorder with sertraline treatment. A randomized controlled trial. Sertraline Premenstrual Dysphoric Collaborative Study Group. 983-8 Premenstrual dysphoric disorder is an important cause (...) of symptoms and functional impairment in menstruating women. To evaluate the efficacy of sertraline hydrochloride for treatment of premenstrual dysphoria by measuring changes in symptom expression and functional impairment. Two screening cycles followed by 1 single-blind placebo cycle and 3 cycles of randomized, double-blind, placebo treatment. Twelve university-affiliated outpatient psychiatry and gynecology clinics. Of the 447 women who requested participation, 243 met criteria for premenstrual

JAMA1997

47. A comparison of the cost-effectiveness of sertraline versus tricyclic antidepressants in primary care

A comparison of the cost-effectiveness of sertraline versus tricyclic antidepressants in primary care A comparison of the cost-effectiveness of sertraline versus tricyclic antidepressants in primary care A comparison of the cost-effectiveness of sertraline versus tricyclic antidepressants in primary care Forder J, Kavanagh S, Fenyo A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Sertraline (a selective serotonin re-uptake inhibitor (SSRI)) versus conventional tricyclic antidepressants (TCA) in treating depression. Type of intervention Treatment. Economic study type Cost-effectiveness analysis. Study population Patients diagnosed and treated for depression in primary care. Depression was defined as five or more symptoms

NHS Economic Evaluation Database.1996

48. Antidepressant pharmacotherapy: economic evaluation of fluoxetine, paroxetine and sertraline in a health maintenance organization

Antidepressant pharmacotherapy: economic evaluation of fluoxetine, paroxetine and sertraline in a health maintenance organization Antidepressant pharmacotherapy: economic evaluation of fluoxetine, paroxetine and sertraline in a health maintenance organization Antidepressant pharmacotherapy: economic evaluation of fluoxetine, paroxetine and sertraline in a health maintenance organization Sclar D A, Robison L M, Skaer T L, Galin R S, Legg R F, Nemec N L, Hughes T E, Buesching D P, Morgan M Record (...) Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Selective Serotonin Reuptake Inhibitors (SSRIs) in antidepressant pharmacotherapy; (a) paroxetine, (b)sertraline, and (c) fluoxetine in the treatment of depression. Type of intervention

NHS Economic Evaluation Database.1995

49. Cost utility of maintenance treatment of recurrent depression with sertraline versus episodic treatment with dothiepin

Cost utility of maintenance treatment of recurrent depression with sertraline versus episodic treatment with dothiepin Cost utility of maintenance treatment of recurrent depression with sertraline versus episodic treatment with dothiepin Cost utility of maintenance treatment of recurrent depression with sertraline versus episodic treatment with dothiepin Hatziandreu E J, Brown R E, Revicki D A, Turner R, Martindale J, Levine S, Siegel J E Record Status This is a critical abstract of an economic (...) , recurrence and discount rates and the number of years of maintenance treatment. The method used was not specified. Estimated benefits used in the economic analysis Sertraline yielded 14.94 QALYs; Dothiepin yielded 14.13 QALYs (both were discounted using a 5% discount rate). Duration of benefits was lifetime. Cost results Lifetime costs were 3,407 for Sertraline and 1,648 for Dothiepin (both discounted at 5%) Synthesis of costs and benefits The incremental cost per Qaly gained of sertraline versus

NHS Economic Evaluation Database.1994