Latest & greatest articles for sepsis

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Top results for sepsis

105. Antibiotic utilisation in very low birth weight infants without sepsis or necrotising enterocolitis is associated with multiple adverse outcomes

Antibiotic utilisation in very low birth weight infants without sepsis or necrotising enterocolitis is associated with multiple adverse outcomes Antibiotic utilisation in very low birth weight infants without sepsis or necrotising enterocolitis is associated with multiple adverse outcomes | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how (...) we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Antibiotic utilisation in very low birth weight infants without sepsis or necrotising

Evidence-Based Medicine (Requires free registration)2017

106. Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis: The HYPRESS Randomized Clinical Trial

Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis: The HYPRESS Randomized Clinical Trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2017

107. Red blood cell transfusions are associated with lower mortality in patients with severe sepsis and septic shock: A propensity-matched analysis

Red blood cell transfusions are associated with lower mortality in patients with severe sepsis and septic shock: A propensity-matched analysis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2017

108. Statement on maternal sepsis

Statement on maternal sepsis WHO IRIS: Statement on maternal sepsis Browse Related links Files in This Item: File Description Size Format 140.69 kB Adobe PDF Title: Statement on maternal sepsis Authors: Issue Date: 2017 Publisher: World Health Organization Place of publication: Geneva Language: English Description: 4 p. Subject: Context: prevention & control Gov't Doc #: WHO/RHR/17.02 URI: License: CC BY-NC-SA 3.0 IGO License URL: Appears in Collections: Items in WHO IRIS are protected

WHO2017

109. High-dose Vitamin C for treatment of sepsis

High-dose Vitamin C for treatment of sepsis High-dose Vitamin C for treatment of sepsis High-dose Vitamin C for treatment of sepsis Mitchell MD, Umscheid CA Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Mitchell MD, Umscheid CA. High-dose Vitamin C for treatment of sepsis. Philadelphia: Center for Evidence-based Practice (CEP). 2017 (...) Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Ascorbic Acid; Humans; Sepsis; Vitamins Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence Center for Evidence-based Practice, University of Pennsylvania Health System, 3535 Market St. Suite 50, Philadelphia PA 19104 Email: Cep2@uphs.upenn.edu AccessionNumber 32018000170 Date abstract record published 16/04/2018 Health

Health Technology Assessment (HTA) Database.2017

110. Protocolised early goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies

Protocolised early goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies Protocolised early goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can (...) goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies Article Text Commentary: Emergency care Protocolised early goal-directed therapy in patients with sepsis/septic shock does not result in improved survival compared with usual care with less invasive resuscitation strategies Joel Meyer 1 , Manu Shankar-Hari 1 , 2 Statistics from Altmetric.com Commentary on : Rowan KM, Angus DC, Bailey M

Evidence-Based Medicine (Requires free registration)2017

111. Clostridium perfringens sepsis complicated by right ventricular cardiogenic shock

Clostridium perfringens sepsis complicated by right ventricular cardiogenic shock 28979559 2018 11 13 1751-1437 18 2 2017 May Journal of the Intensive Care Society J Intensive Care Soc Clostridium perfringens sepsis complicated by right ventricular cardiogenic shock. 130-137 10.1177/1751143716683713 Clostridium perfringens sepsis has been ascribed a dismal prognosis when associated with massive intravascular haemolysis. We present a 71-year-old woman's fatal case which was compounded (...) Care Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Barker Graham G Department of Critical Care Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Garry David D Department of Critical Care Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. eng Journal Article 2016 12 19 England J Intensive Care Soc 101538668 1751-1437 Clostridium sepsis haemolysis methaemoglobin right ventricular failure ventriculo-arterial coupling 2017 10 6 6 0 2017 10 6 6

Journal of the Intensive Care Society2016 Full Text: Link to full Text with Trip Pro

112. The microcirculation and its measurement in sepsis

The microcirculation and its measurement in sepsis 29118834 2018 11 13 1751-1437 18 3 2017 Aug Journal of the Intensive Care Society J Intensive Care Soc The microcirculation and its measurement in sepsis. 221-227 10.1177/1751143716678638 The microcirculation describes the smallest elements of the cardiovascular conducting system and is pivotal in the maintenance of homeostasis. Microcirculatory dysfunction is present early in the pathophysiology of sepsis, with the extent of microcirculatory (...) derangement relating to disease severity and prognosis in ICU patients. However, at present microcirculatory function is not routinely monitored at the bedside. This article describes the pathophysiology of microcirculatory derangements in sepsis, methods of its measurement and evidence to support their clinical use. Charlton Matthew M Anaesthetics and Critical Care, Diagnostic Development Unit, University of Leicester, Leicester, UK. Sims Mark M Astrobiology and Space Instrumentation, Diagnostic

Journal of the Intensive Care Society2016 Full Text: Link to full Text with Trip Pro

113. Continuous versus Intermittent ?-Lactam Infusion in Severe Sepsis. A Meta-analysis of Individual Patient Data from Randomized Trials

Continuous versus Intermittent ?-Lactam Infusion in Severe Sepsis. A Meta-analysis of Individual Patient Data from Randomized Trials PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2016

114. Protocolized Treatment Is Associated With Decreased Organ Dysfunction in Pediatric Severe Sepsis

Protocolized Treatment Is Associated With Decreased Organ Dysfunction in Pediatric Severe Sepsis PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2016

115. The Effect of Selenium Therapy on Mortality in Patients With Sepsis Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

The Effect of Selenium Therapy on Mortality in Patients With Sepsis Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2016

116. Continuous versus Intermittent beta-Lactam Infusion in Severe Sepsis. A Meta-analysis of Individual Patient Data from Randomized Trials

Continuous versus Intermittent beta-Lactam Infusion in Severe Sepsis. A Meta-analysis of Individual Patient Data from Randomized Trials 26974879 2016 09 16 2016 09 16 1535-4970 194 6 2016 Sep 15 American journal of respiratory and critical care medicine Am. J. Respir. Crit. Care Med. Continuous versus Intermittent β-Lactam Infusion in Severe Sepsis. A Meta-analysis of Individual Patient Data from Randomized Trials. 681-91 10.1164/rccm.201601-0024OC Optimization of β-lactam antibiotic dosing (...) for critically ill patients is an intervention that may improve outcomes in severe sepsis. In this individual patient data meta-analysis of critically ill patients with severe sepsis, we aimed to compare clinical outcomes of those treated with continuous versus intermittent infusion of β-lactam antibiotics. We identified relevant randomized controlled trials comparing continuous versus intermittent infusion of β-lactam antibiotics in critically ill patients with severe sepsis. We assessed the quality

EvidenceUpdates2016

117. Association Among Blood Transfusion, Sepsis, and Decreased Long-term Survival After Colon Cancer Resection

Association Among Blood Transfusion, Sepsis, and Decreased Long-term Survival After Colon Cancer Resection 27631770 2016 09 15 2016 09 15 1528-1140 2016 Sep 14 Annals of surgery Ann. Surg. Association Among Blood Transfusion, Sepsis, and Decreased Long-term Survival After Colon Cancer Resection. To investigate the potential additive effects of blood transfusion and sepsis on colon cancer disease-specific survival, cardiovascular disease-specific survival, and overall survival after colon cancer (...) surgery. Perioperative blood transfusions are associated with infectious complications and increased risk of cancer recurrence through systemic inflammatory effects. Furthermore, recent studies have suggested an association among sepsis, subsequent systemic inflammation, and adverse cardiovascular outcomes. However, no study has investigated the association among transfusion, sepsis, and disease-specific survival in postoperative patients. The New York State Cancer Registry and Statewide Planning

EvidenceUpdates2016

118. Empirical Micafungin Treatment and Survival Without Invasive Fungal Infection in Adults With ICU-Acquired Sepsis, Candida Colonization, and Multiple Organ Failure: The EMPIRICUS Randomized Clinical Trial.

Empirical Micafungin Treatment and Survival Without Invasive Fungal Infection in Adults With ICU-Acquired Sepsis, Candida Colonization, and Multiple Organ Failure: The EMPIRICUS Randomized Clinical Trial. Importance: Although frequently used in treating intensive care unit (ICU) patients with sepsis, empirical antifungal therapy, initiated for suspected fungal infection, has not been shown to improve outcome. Objective: To determine whether empirical micafungin reduces invasive fungal infection (...) (IFI)-free survival at day 28. Design, Setting, and Participants: Multicenter double-blind placebo-controlled study of 260 nonneutropenic, nontransplanted, critically ill patients with ICU-acquired sepsis, multiple Candida colonization, multiple organ failure, exposed to broad-spectrum antibacterial agents, and enrolled between July 2012 and February 2015 in 19 French ICUs. Interventions: Empirical treatment with micafungin (100 mg, once daily, for 14 days) (n = 131) vs placebo (n = 129). Main

JAMA2016 Full Text: Link to full Text with Trip Pro

119. Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis.

Levosimendan for the Prevention of Acute Organ Dysfunction in Sepsis. BACKGROUND: Levosimendan is a calcium-sensitizing drug with inotropic and other properties that may improve outcomes in patients with sepsis. METHODS: We conducted a double-blind, randomized clinical trial to investigate whether levosimendan reduces the severity of organ dysfunction in adults with sepsis. Patients were randomly assigned to receive a blinded infusion of levosimendan (at a dose of 0.05 to 0.2 μg per kilogram (...) in the levosimendan group were less likely than those in the placebo group to be successfully weaned from mechanical ventilation over the period of 28 days (hazard ratio, 0.77; 95% CI, 0.60 to 0.97; P=0.03). More patients in the levosimendan group than in the placebo group had supraventricular tachyarrhythmia (3.1% vs. 0.4%; absolute difference, 2.7 percentage points; 95% CI, 0.1 to 5.3; P=0.04). CONCLUSIONS: The addition of levosimendan to standard treatment in adults with sepsis was not associated with less

NEJM2016 Full Text: Link to full Text with Trip Pro

120. Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis: The HYPRESS Randomized Clinical Trial.

Effect of Hydrocortisone on Development of Shock Among Patients With Severe Sepsis: The HYPRESS Randomized Clinical Trial. Importance: Adjunctive hydrocortisone therapy is suggested by the Surviving Sepsis Campaign in refractory septic shock only. The efficacy of hydrocortisone in patients with severe sepsis without shock remains controversial. Objective: To determine whether hydrocortisone therapy in patients with severe sepsis prevents the development of septic shock. Design, Setting (...) , and Participants: Double-blind, randomized clinical trial conducted from January 13, 2009, to August 27, 2013, with a follow-up of 180 days until February 23, 2014. The trial was performed in 34 intermediate or intensive care units of university and community hospitals in Germany, and it included 380 adult patients with severe sepsis who were not in septic shock. Interventions: Patients were randomly allocated 1:1 either to receive a continuous infusion of 200 mg of hydrocortisone for 5 days followed by dose

JAMA2016 Full Text: Link to full Text with Trip Pro