Latest & greatest articles for sedation

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Top results for sedation

41. Effect of Conscious Sedation vs General Anesthesia on Early Neurological Improvement Among Patients With Ischemic Stroke Undergoing Endovascular Thrombectomy: A Randomized Clinical Trial.

Effect of Conscious Sedation vs General Anesthesia on Early Neurological Improvement Among Patients With Ischemic Stroke Undergoing Endovascular Thrombectomy: A Randomized Clinical Trial. Importance: Optimal management of sedation and airway during thrombectomy for acute ischemic stroke is controversial due to lack of evidence from randomized trials. Objective: To assess whether conscious sedation is superior to general anesthesia for early neurological improvement among patients receiving (...) stroke thrombectomy. Design, Setting, and Participants: SIESTA (Sedation vs Intubation for Endovascular Stroke Treatment), a single-center, randomized, parallel-group, open-label treatment trial with blinded outcome evaluation conducted at Heidelberg University Hospital in Germany (April 2014-February 2016) included 150 patients with acute ischemic stroke in the anterior circulation, higher National Institutes of Health Stroke Scale (NIHSS) score (>10), and isolated/combined occlusion at any level

JAMA2016

42. Early Bispectral Index and Sedation Requirements During Therapeutic Hypothermia Predict Neurologic Recovery Following Cardiac Arrest

Early Bispectral Index and Sedation Requirements During Therapeutic Hypothermia Predict Neurologic Recovery Following Cardiac Arrest PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2016

43. Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial

Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial 27460905 2016 08 24 2016 10 25 1097-6760 68 5 2016 Nov Annals of emergency medicine Ann Emerg Med Propofol or Ketofol for Procedural Sedation and Analgesia in Emergency Medicine-The POKER Study: A Randomized Double-Blind Clinical Trial. 574-582.e1 S0196-0644(16)30204-9 10.1016/j.annemergmed.2016.05.024 We determine whether emergency physician-provided deep (...) sedation with 1:1 ketofol versus propofol results in fewer adverse respiratory events requiring physician intervention when used for procedural sedation and analgesia. Consenting patients requiring deep sedation were randomized to receive either ketofol or propofol in a double-blind fashion according to a weight-based dosing schedule. The primary outcome was the occurrence of a respiratory adverse event (desaturation, apnea, or hypoventilation) requiring an intervention by the sedating physician

EvidenceUpdates2016

44. Moderate Procedural Sedation in Adult Patients: Guidelines

Moderate Procedural Sedation in Adult Patients: Guidelines Moderate Procedural Sedation in Adult Patients: Guidelines | CADTH.ca Find the information you need Moderate Procedural Sedation in Adult Patients: Guidelines Moderate Procedural Sedation in Adult Patients: Guidelines Published on: September 26, 2016 Project Number: RB1025-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What are the evidence-based guidelines regarding (...) moderate procedural sedation for adult patients? Key Message Three evidence-based guidelines were identified regarding moderate procedural sedation for adult patients. Tags anesthesia, diagnostic tests, digestive system, emergency medicine, analgesia, analgesics, benzodiazepines, conscious sedation, diagnostic imaging, emergency medical services, emergency service, hospital, emergency treatment, endoscopy, endoscopy, digestive system, etomidate, fentanyl, hypnotics and sedatives, midazolam, morphine

Canadian Agency for Drugs and Technologies in Health - Rapid Review2016

45. Dexmedetomidine for ICU Sedation

Dexmedetomidine for ICU Sedation Dexmedetomidine for ICU Sedation: a Cost-Effectiveness Analysis | CADTH.ca Find the information you need Dexmedetomidine for ICU Sedation: a Cost-Effectiveness Analysis Dexmedetomidine for ICU Sedation: a Cost-Effectiveness Analysis Published on: September 8, 2016 Project Number: HT0015 Product Line: Technology Review Research Type: Devices and Systems Result type: Report The number of drugs available for sedation of patients in the intensive care unit (ICU) is (...) limited, with both benzodiazepines and propofol being commonly used. Dexmedetomidine is a selective alpha-2 adrenergic agonist with sedative properties; it produces a pattern of sedation different from other drugs. The choice of sedative drugs in the ICU setting is important, as the drug selected can affect patient outcomes, making their use an important formulary policy decision for acute-care hospitals. Decisions will be made from a quality of care and a budgetary perspective, as substantial cost

CADTH - Health Technology Assessment2016

46. Dexmedetomidine for ICU Sedation: a Cost-Effectiveness Analysis

Dexmedetomidine for ICU Sedation: a Cost-Effectiveness Analysis Dexmedetomidine for ICU Sedation: a Cost-Effectiveness Analysis | CADTH.ca Find the information you need Dexmedetomidine for ICU Sedation: a Cost-Effectiveness Analysis Dexmedetomidine for ICU Sedation: a Cost-Effectiveness Analysis Published on: September 8, 2016 Project Number: HT0015 Product Line: Technology Review Research Type: Devices and Systems Result type: Report The number of drugs available for sedation of patients (...) in the intensive care unit (ICU) is limited, with both benzodiazepines and propofol being commonly used. Dexmedetomidine is a selective alpha-2 adrenergic agonist with sedative properties; it produces a pattern of sedation different from other drugs. The choice of sedative drugs in the ICU setting is important, as the drug selected can affect patient outcomes, making their use an important formulary policy decision for acute-care hospitals. Decisions will be made from a quality of care and a budgetary

CADTH - Plasma Products2016

47. What Works and What's Safe in Pediatric Emergency Procedural Sedation: An Overview of Reviews

What Works and What's Safe in Pediatric Emergency Procedural Sedation: An Overview of Reviews 26858095 2016 04 28 2017 03 29 1553-2712 23 5 2016 05 Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med What Works and What's Safe in Pediatric Emergency Procedural Sedation: An Overview of Reviews. 519-30 10.1111/acem.12938 Sedation is increasingly used to facilitate procedures on children in emergency departments (EDs). This overview (...) of systematic reviews (SRs) examines the safety and efficacy of sedative agents commonly used for procedural sedation in children in the ED or similar settings. We followed standard SR methods: comprehensive search; dual study selection, quality assessment, data extraction. We included SRs of children (1 month to 18 years) where the indication for sedation was procedure-related and performed in the ED. Fourteen SRs were included (210 primary studies). The most data were available for propofol (six reviews

EvidenceUpdates2016

48. Inadequate Sedation During Therapeutic Paralysis: Use of Bispectral Index in Critically Ill Patients

Inadequate Sedation During Therapeutic Paralysis: Use of Bispectral Index in Critically Ill Patients 27398299 2018 11 13 2199-1154 3 2 2016 Jun Drugs - real world outcomes Drugs Real World Outcomes Inadequate Sedation During Therapeutic Paralysis: Use of Bispectral Index in Critically Ill Patients. 201-208 Patients receiving therapeutic paralysis may experience inadequate sedation due to intrinsic limitations of behavioral sedation assessment. Bispectral index (BIS™) provides an objective (...) measure of sedation; however, the role of BIS™ is not well defined in intensive care unit (ICU) patients on neuromuscular blocking agents (NMBA). The aim of this study was to delineate the relationship between BIS™ and level of sedation for critically ill patients during therapeutic paralysis. This was a retrospective observational study conducted in ICU patients receiving continuous infusion NMBA and BIS™ monitoring. The primary endpoint was the correlation of BIS™ <60 during therapeutic paralysis

Drugs - real world outcomes2016 Full Text: Link to full Text with Trip Pro

49. Daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol: A randomized controlled trial

Daily sedation interruption in mechanically ventilated critically ill patients cared for with a sedation protocol: A randomized controlled trial PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2016

50. Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review

Alpha-2 agonists for sedation of mechanically ventilated adults in intensive care units: a systematic review Journals Library Journals Library An error has occurred in processing the XML document An error has occurred in processing the XML document An error has occurred in processing the XML document An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from

NIHR HTA programme2016

51. Virtual Reality for Pediatric Sedation: A Randomized Controlled Trial Using Simulation.

Virtual Reality for Pediatric Sedation: A Randomized Controlled Trial Using Simulation. 27014520 2016 03 25 2016 03 25 2017 02 20 8 2 2016 Feb 09 Cureus Cureus Virtual Reality for Pediatric Sedation: A Randomized Controlled Trial Using Simulation. e486 10.7759/cureus.486 Team training for procedural sedation for pediatric residents has traditionally consisted of didactic presentations and simulated scenarios using high-fidelity mannequins. We assessed the effectiveness of a virtual reality (...) module in teaching preparation for and management of sedation for procedures. After developing a virtual reality environment in Second Life® (Linden Lab, San Francisco, CA) where providers perform and recover patients from procedural sedation, we conducted a randomized controlled trial to assess the effectiveness of the virtual reality module versus a traditional web-based educational module. A 20 question pre- and post-test was administered to assess knowledge change. All subjects participated

Curēus2016 Full Text: Link to full Text with Trip Pro

52. The Optimal Dose for Oral Midazolam in Order to Achieve Effective Sedation Levels in Pediatric Patients is 0.75mg/kg, as shown by a single trial of ninety patients.

The Optimal Dose for Oral Midazolam in Order to Achieve Effective Sedation Levels in Pediatric Patients is 0.75mg/kg, as shown by a single trial of ninety patients. UTCAT3045, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title The Optimal Dose for Oral Midazolam in Order to Achieve Effective Sedation Levels in Pediatric Patients is 0.75mg/kg, as shown by a single trial of ninety patients. Clinical Question What (...) is the optimal dosage of oral midazolam in order to achieve effective sedation levels in pediatric dental patients? Clinical Bottom Line For pediatric dental patients, the oral dose of midazolam of 0.75mg/kg has a high level of sedation and cooperation, without increasing adverse effects, as opposed to the standard dose of 0.5mg/kg. This is based on a single trial of ninety patients. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type

UTHSCSA Dental School CAT Library2016

53. Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures

Monitoring and Management of Pediatric Patients Before, During, and After Sedation for Diagnostic and Therapeutic Procedures

American Academy of Pediatric Dentistry2016

54. SCAI/CCAS/SPA Expert Consensus Statement for Anesthesia and Sedation Practice: Recommendations for Patients Undergoing Diagnostic and Therapeutic Procedures in the Pediatric and Congenital Cardiac Catheterization Laboratory

SCAI/CCAS/SPA Expert Consensus Statement for Anesthesia and Sedation Practice: Recommendations for Patients Undergoing Diagnostic and Therapeutic Procedures in the Pediatric and Congenital Cardiac Catheterization Laboratory

Society for Cardiovascular Angiography and Interventions2016

55. Practice Advisory: FDA Warnings Regarding Use of General Anesthetics and Sedation Drugs in Young Children and Pregnant Women

Practice Advisory: FDA Warnings Regarding Use of General Anesthetics and Sedation Drugs in Young Children and Pregnant Women Practice Advisory: FDA Warnings Regarding Use of General Anesthetics and Sedation Drugs in Young Children and Pregnant Women - ACOG Menu ▼ Practice Advisory: FDA Warnings Regarding Use of General Anesthetics and Sedation Drugs in Young Children and Pregnant Women Page Navigation ▼ Share: Practice Advisory: FDA Warnings Regarding Use of General Anesthetics and Sedation (...) Drugs in Young Children and Pregnant Women December 21, 2016 This is an area of evolving care and practice. Fellows should check periodically for revisions and updates. ACOG will communicate important changes and updates to these guidelines. On December 14, 2016, the U.S. Food and Drug Administration (FDA) published a Drug Safety Communications entitled " " (1,2). In this announcement, the FDA announced that it will require warnings to be added to the labels of general anesthetic and sedation drugs

American College of Obstetricians and Gynecologists2016

57. Prospective evaluation of sedation-related adverse events in pediatric patients ventilated for acute respiratory failure

Prospective evaluation of sedation-related adverse events in pediatric patients ventilated for acute respiratory failure PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2015

58. Sedation versus general anaesthesia for provision of dental treatment to patients younger than 18 years.

Sedation versus general anaesthesia for provision of dental treatment to patients younger than 18 years. BACKGROUND: A significant proportion of children have caries requiring restorations or extractions, and some of these children will not accept this treatment under local anaesthetic. Historically this has been managed by the use of a general anaesthetic in children; however, use of sedation may lead to reduced morbidity and cost. The aim of this review was to compare the efficiency (...) of sedation versus general anaesthesia (GA) for provision of dental treatment to children and adolescents younger than 18 years. This review was originally published in 2009 and was updated in 2012 and again in 2015. OBJECTIVES: We will evaluate morbidity and effectiveness of sedation versus GA for provision of dental treatment to patients younger than 18 years. If data become available, we will analyse the cost-effectiveness of different interventions. If data are not available, we will obtain crude

Cochrane2015

59. The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients

The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients 26113020 2015 07 15 2016 02 03 2017 02 20 1553-2712 22 7 2015 Jul Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients. 878-82 10.1111/acem.12706 Delirium is frequently missed (...) in older emergency department (ED) patients. Brief (<2 minutes) delirium assessments have been validated for the ED, but some ED health care providers may consider them to be cumbersome. The Richmond Agitation Sedation Scale (RASS) is an observational scale that quantifies level of consciousness and takes less than 10 seconds to perform. The authors sought to explore the diagnostic accuracy of the RASS for delirium in older ED patients. This was a preplanned analysis of a prospective observational

EvidenceUpdates2015