Latest & greatest articles for rosuvastatin

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Top results for rosuvastatin

1. Efficacy and safety of fixed-dose combination therapy with gemigliptin (50 mg) and rosuvastatin compared with monotherapy in patients with type 2 diabetes and dyslipidaemia (BALANCE): A multicentre, randomized, double-blind, controlled, phase 3 trial

Efficacy and safety of fixed-dose combination therapy with gemigliptin (50 mg) and rosuvastatin compared with monotherapy in patients with type 2 diabetes and dyslipidaemia (BALANCE): A multicentre, randomized, double-blind, controlled, phase 3 trial 30084112 2018 09 05 1463-1326 2018 Aug 06 Diabetes, obesity & metabolism Diabetes Obes Metab Efficacy and safety of fixed-dose combination therapy with gemigliptin (50 mg) and rosuvastatin compared with monotherapy in patients with type 2 diabetes (...) and dyslipidaemia (BALANCE): A multicentre, randomized, double-blind, controlled, phase 3 trial. 10.1111/dom.13491 To evaluate the efficacy and safety of a fixed-dose combination (FDC) of gemigliptin and rosuvastatin in patients with type 2 diabetes and dyslipidaemia. A total of 33 hospitals in Korea participated in this randomized, double-blind trial of diabetic patients with dyslipidaemia. A total of 290 participants were randomly assigned at a 1:1:1 ratio to receive an FDC of gemigliptin (50 mg

EvidenceUpdates2018

2. Rosuvastatin

Rosuvastatin Top results for rosuvastatin - Trip Database or use your Google+ account Liberating the literature My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing (...) the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for rosuvastatin The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines

Trip Latest and Greatest2018

3. Efficacy of Rosuvastatin in Children With Homozygous Familial Hypercholesterolemia and Association With Underlying Genetic Mutations

Efficacy of Rosuvastatin in Children With Homozygous Familial Hypercholesterolemia and Association With Underlying Genetic Mutations 28838366 2017 08 25 2017 09 01 2017 09 01 1558-3597 70 9 2017 Aug 29 Journal of the American College of Cardiology J. Am. Coll. Cardiol. Efficacy of Rosuvastatin in Children With Homozygous Familial Hypercholesterolemia and Association With Underlying Genetic Mutations. 1162-1170 S0735-1097(17)38003-8 10.1016/j.jacc.2017.06.058 Homozygous familial (...) hypercholesterolemia (HoFH), a rare genetic disorder, is characterized by extremely elevated levels of low-density lipoprotein cholesterol (LDL-C) and accelerated atherosclerotic cardiovascular disease. Statin treatment starts at diagnosis, but no statin has been formally evaluated in, or approved for, HoFH children. The authors sought to assess the LDL-C efficacy of rosuvastatin versus placebo in HoFH children, and the relationship with underlying genetic mutations. This was a randomized, double-blind, 12-week

EvidenceUpdates2017

4. Association of Lipoproteins, Insulin Resistance, and Rosuvastatin With Incident Type 2 Diabetes Mellitus : Secondary Analysis of a Randomized Clinical Trial.

Association of Lipoproteins, Insulin Resistance, and Rosuvastatin With Incident Type 2 Diabetes Mellitus : Secondary Analysis of a Randomized Clinical Trial. 27347563 2016 07 24 2017 05 01 2380-6591 1 2 2016 May 01 JAMA cardiology JAMA Cardiol Association of Lipoproteins, Insulin Resistance, and Rosuvastatin With Incident Type 2 Diabetes Mellitus : Secondary Analysis of a Randomized Clinical Trial. 136-45 10.1001/jamacardio.2016.0096 Statins decrease levels of low-density lipoprotein (LDL) and (...) -controlled randomized clinical trial) was conducted at 1315 sites in 26 countries and enrolled 17 802 men 50 years or older and women 60 years or older with LDL cholesterol levels less than 130 mg/dL, high-sensitivity C-reactive protein levels of at least 2 mg/L, and triglyceride levels less than 500 mg/dL. Those with T2DM were excluded. A prespecified secondary aim was to assess the effect of rosuvastatin calcium on T2DM. Incident T2DM was monitored for a median of 2.0 years. Data were collected from

JAMA cardiology2016

5. Perioperative Rosuvastatin in Cardiac Surgery.

Perioperative Rosuvastatin in Cardiac Surgery. BACKGROUND: Complications after cardiac surgery are common and lead to substantial increases in morbidity and mortality. Meta-analyses of small randomized trials have suggested that perioperative statin therapy can prevent some of these complications. METHODS: We randomly assigned 1922 patients in sinus rhythm who were scheduled for elective cardiac surgery to receive perioperative rosuvastatin (at a dose of 20 mg daily) or placebo. The primary (...) and C-reactive protein after surgery were lower in patients assigned to rosuvastatin than in those assigned to placebo (P<0.001). However, the rate of postoperative atrial fibrillation did not differ significantly between the rosuvastatin group and the placebo group (21.1% and 20.5%, respectively; odds ratio 1.04; 95% confidence interval [CI], 0.84 to 1.30; P=0.72), nor did the area under the troponin I-release curve (102 ng×hour per milliliter and 100 ng×hour per milliliter, respectively; between-group

NEJM2016

6. The Effect of High Dose Cilostazol and Rosuvastatin on Periprocedural Myocardial Injury in Patients with Elective Percutaneous Coronary Intervention.

The Effect of High Dose Cilostazol and Rosuvastatin on Periprocedural Myocardial Injury in Patients with Elective Percutaneous Coronary Intervention. 27122885 2016 04 28 2016 04 28 2017 02 20 1011-6842 31 4 2015 Jul Acta Cardiologica Sinica Acta Cardiol Sin The Effect of High Dose Cilostazol and Rosuvastatin on Periprocedural Myocardial Injury in Patients with Elective Percutaneous Coronary Intervention. 292-300 The aim of our study was to assess the effect of pretreatment with cilostazol (...) and rosuvastatin combination before elective percutaneous coronary intervention (PCI) on peri-procedural myocardial injury (PPMIJ). We randomly assigned 172 patients with stable angina pectoris scheduled for elective PCI to pre- treatment with Cilostazol 200mg and Rosuvastatin 40 mg (group 1), or to pretreatment with Rosuvastatin 40 mg group (group 2). The primary end-point was the occurrence of PPMIJ defined as any cardiac troponin I (Tn I) level elevated above the upper normal limit (UNL). The occurrence

Zhonghua Minguo xin zang xue hui za zhi = Acta Cardiologica Sinica2016

7. Randomised controlled trial: In individuals at intermediate risk for cardiovascular disease, treatment with rosuvastatin but not candesartan plus hydrochlorothiazide lowers cardiovascular disease event rates

Randomised controlled trial: In individuals at intermediate risk for cardiovascular disease, treatment with rosuvastatin but not candesartan plus hydrochlorothiazide lowers cardiovascular disease event rates In individuals at intermediate risk for cardiovascular disease, treatment with rosuvastatin but not candesartan plus hydrochlorothiazide lowers cardiovascular disease event rates | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use (...) of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here In individuals at intermediate risk for cardiovascular disease, treatment with rosuvastatin but not candesartan plus

Evidence-Based Medicine (Requires free registration)2016

8. Impact of Rosuvastatin on Contrast-Induced Acute Kidney Injury in Patients at High Risk for Nephropathy Undergoing Elective Angiography

Impact of Rosuvastatin on Contrast-Induced Acute Kidney Injury in Patients at High Risk for Nephropathy Undergoing Elective Angiography 25670636 2015 03 17 2015 05 19 2016 11 25 1879-1913 115 7 2015 Apr 01 The American journal of cardiology Am. J. Cardiol. Impact of Rosuvastatin on contrast-induced acute kidney injury in patients at high risk for nephropathy undergoing elective angiography. 867-71 10.1016/j.amjcard.2015.01.007 S0002-9149(15)00042-9 Although statins have been shown to prevent (...) contrast-induced acute kidney injury in patients with acute coronary syndromes, the benefit of statins is not known for patients at high risk for nephropathy who undergo elective coronary angiography. Two hundred twenty consecutive statin-naive patients with chronic kidney disease (estimated glomerular filtration rate <60 ml/min/1.73 m(2)) who underwent elective coronary or peripheral angiography were randomly assigned to receive rosuvastatin (40 mg on admission, followed by 20 mg/day; n = 110

EvidenceUpdates2015

9. Rosuvastatin for Sepsis-Associated Acute Respiratory Distress Syndrome

Rosuvastatin for Sepsis-Associated Acute Respiratory Distress Syndrome PEDSCCM.org Criteria abstracted from series in Review Posted: founded 1995 Questions or comments?

PedsCCM Evidence-Based Journal Club2015

10. Rosuvastatin for sepsis-associated acute respiratory distress syndrome.

Rosuvastatin for sepsis-associated acute respiratory distress syndrome. BACKGROUND: In the acute respiratory distress syndrome (ARDS), inflammation in the lungs and other organs can cause life-threatening organ failure. Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (statins) can modulate inflammatory responses. Previous observational studies suggested that statins improved clinical outcomes in patients with sepsis. We hypothesized that rosuvastatin therapy would improve clinical (...) outcomes in critically ill patients with sepsis-associated ARDS. METHODS: We conducted a multicenter trial in which patients with sepsis-associated ARDS were randomly assigned to receive either enteral rosuvastatin or placebo in a double-blind manner. The primary outcome was mortality before hospital discharge home or until study day 60 if the patient was still in a health care facility. Secondary outcomes included the number of ventilator-free days (days that patients were alive and breathing

NEJM2014

11. Loading Dose of Rosuvastatin Before PCI and its Beneficial Post-Procedural Effects: A Systematic Review

Loading Dose of Rosuvastatin Before PCI and its Beneficial Post-Procedural Effects: A Systematic Review "Loading Dose of Rosuvastatin Before PCI and its Beneficial Post-Proced" by Andrew Ravella Galli < > > > > > Title Author Date of Award Summer 8-9-2014 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Mark Pedemonte MD Rights . Abstract Background: Many patients with acute coronary syndrome in the United States electively choose (...) of rosuvastatin before percutaneous coronary intervention (PCI) improve mid and long term outcomes? Methods: An exhaustive search of available medical literature was conducted using Medline-OVID, EBSCO, CINAHL, Health Source-Consumer, and Web of Science using the keywords: rosuvastatin and percutaneous coronary intervention. Relevant articles were assessed for quality using GRADE. Results: Three studies, with one including a 12-month follow up study met inclusion criteria. A prospective randomized trial

Pacific University EBM Capstone Project2014

12. Rosuvastatin for Sepsis-Associated Acute Respiratory Distress Syndrome.

Rosuvastatin for Sepsis-Associated Acute Respiratory Distress Syndrome. 24835849 2014 06 06 2014 06 10 2016 12 28 1533-4406 370 23 2014 Jun 05 The New England journal of medicine N. Engl. J. Med. Rosuvastatin for sepsis-associated acute respiratory distress syndrome. 2191-200 10.1056/NEJMoa1401520 In the acute respiratory distress syndrome (ARDS), inflammation in the lungs and other organs can cause life-threatening organ failure. Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (...) (statins) can modulate inflammatory responses. Previous observational studies suggested that statins improved clinical outcomes in patients with sepsis. We hypothesized that rosuvastatin therapy would improve clinical outcomes in critically ill patients with sepsis-associated ARDS. We conducted a multicenter trial in which patients with sepsis-associated ARDS were randomly assigned to receive either enteral rosuvastatin or placebo in a double-blind manner. The primary outcome was mortality before

NEJM2014 Full Text: Link to full Text with Trip Pro

13. Cost-effectiveness of rosuvastatin in comparison with generic atorvastatin and simvastatin in a Swedish population at high risk of cardiovascular events

Cost-effectiveness of rosuvastatin in comparison with generic atorvastatin and simvastatin in a Swedish population at high risk of cardiovascular events Cost-effectiveness of rosuvastatin in comparison with generic atorvastatin and simvastatin in a Swedish population at high risk of cardiovascular events Cost-effectiveness of rosuvastatin in comparison with generic atorvastatin and simvastatin in a Swedish population at high risk of cardiovascular events Gandhi SK, Jensen MM, Fox KM, Smolen L (...) concluded that rosuvastatin was cost-effective, over a lifetime, compared with generic simvastatin or atorvastatin. The lack of detailed reporting and the highlighted limitations to this study mean that the authors’ conclusions should be considered with caution. Type of economic evaluation Cost-effectiveness analysis, cost-utility analysis Study objective This study evaluated the long-term cost-effectiveness of alternative statin therapies in Swedish patients with a high risk of cardiovascular events

NHS Economic Evaluation Database.2012

14. Cost-effectiveness of rosuvastatin 20mg for the prevention of cardiovascular morbidity and mortality: a Swedish economic evaluation of the JUPITER trial

Cost-effectiveness of rosuvastatin 20mg for the prevention of cardiovascular morbidity and mortality: a Swedish economic evaluation of the JUPITER trial Cost-effectiveness of rosuvastatin 20mg for the prevention of cardiovascular morbidity and mortality: a Swedish economic evaluation of the JUPITER trial Cost-effectiveness of rosuvastatin 20mg for the prevention of cardiovascular morbidity and mortality: a Swedish economic evaluation of the JUPITER trial Ohsfeldt RL, Olsson AG, Jensen MM (...) , Gandhi SK, Paulsson T Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The study examined cost-effectiveness of rosuvastatin for primary prevention of major cardiovascular disease for various risk levels. The authors concluded that primary

NHS Economic Evaluation Database.2012

15. Rosuvastatin (Crestor) - Prevention of major cardiovascular events in patients who are estimated to have a high risk for a first cardiovascular event as an adjunct to correction of other risk factors

Rosuvastatin (Crestor) - Prevention of major cardiovascular events in patients who are estimated to have a high risk for a first cardiovascular event as an adjunct to correction of other risk factors

Scottish Medicines Consortium2011

16. Effects of Rosuvastatin on Progression of Stenosis in Adult Patients With Congenital Aortic Stenosis (PROCAS Trial).

Effects of Rosuvastatin on Progression of Stenosis in Adult Patients With Congenital Aortic Stenosis (PROCAS Trial). 21565321 2011 06 29 2011 09 22 2016 11 25 1879-1913 108 2 2011 Jul 15 The American journal of cardiology Am. J. Cardiol. Effects of rosuvastatin on progression of stenosis in adult patients with congenital aortic stenosis (PROCAS Trial). 265-71 10.1016/j.amjcard.2011.03.032 Recent trials have failed to show that statin therapy halts the progression of calcific aortic stenosis (...) (AS). We hypothesized that statin therapy in younger patients with congenital AS would be more beneficial, because the valve is less calcified. In the present double-blind, placebo-controlled trial, 63 patients with congenital AS (age 18 to 45 years) were randomly assigned to receive either 10 mg of rosuvastatin daily (n = 30) or matched placebo (n = 33). The primary end point was the progression of peak aortic valve velocity. The secondary end points were temporal changes in the left ventricular mass

EvidenceUpdates2011

17. Comparative effectiveness of rosuvastatin versus other statins: a review of clinical effectiveness

Comparative effectiveness of rosuvastatin versus other statins: a review of clinical effectiveness Comparative effectiveness of rosuvastatin versus other statins: a review of clinical effectiveness Comparative effectiveness of rosuvastatin versus other statins: a review of clinical effectiveness Canadian Agency for Drugs and Technologies in Health Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality (...) of this assessment has been made for the HTA database. Citation Canadian Agency for Drugs and Technologies in Health. Comparative effectiveness of rosuvastatin versus other statins: a review of clinical effectiveness. Ottawa: Canadian Agency for Drugs and Technologies in Health (CADTH). 2011 Authors' conclusions Evidence suggests that rosuvastatin has the most potent per milligram LDL lowering effect but with appropriate dosage adjustments different statins can provide equivalent LDL reductions. Data suggests

Health Technology Assessment (HTA) Database.2011

18. The cost-effectiveness of C-reactive protein testing and rosuvastatin treatment for patients with normal cholesterol levels

The cost-effectiveness of C-reactive protein testing and rosuvastatin treatment for patients with normal cholesterol levels The cost-effectiveness of C-reactive protein testing and rosuvastatin treatment for patients with normal cholesterol levels The cost-effectiveness of C-reactive protein testing and rosuvastatin treatment for patients with normal cholesterol levels Choudhry NK, Patrick AR, Glynn RJ, Avorn J Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study examined the cost-effectiveness of rosuvastatin for apparently healthy men over 50 years old and women over 60 years old, with elevated high-sensitivity C-reactive protein levels (2mg/L or more), but normal low-density lipoprotein cholesterol levels (less than

NHS Economic Evaluation Database.2011

19. Rosuvastatin(Crestor)

Rosuvastatin(Crestor) 2011. DAR No 4. Rosuvastatin (Crestor®) - navarra.es Castellano | Euskara | Français | English Use the search tool! Search engine : : : : : : : : DAR No 4. Rosuvastatin (Crestor®) DAR No 4. Rosuvastatin (Crestor®) Content tools Share it Another statin! Expensive, potent and doubts on safety Rosuvastatin is the seventh commercialized statin in Spain. Its capacity to lower cholesterol levels is similar to other statins at equivalent doses. No advantage has been shown

Drug and Therapeutics Bulletin of Navarre (Spain)2011

20. Rosuvastatin and the JUPITER trial. A critical appraisal

Rosuvastatin and the JUPITER trial. A critical appraisal Volumen 18. DTB: Vol 18, No 5. November - December 2010 - navarra.es Castellano | Euskara | Français | English Use the search tool! Search engine : : : : : : : : DTB: Vol 18, No 5. November - December 2010 DTB: Vol 18, No 5. November - December 2010 Content tools Share it Rosuvastatin and the JUPITER trial. A critical appraisal The role of hs-CRP in the pathogenesis of atherosclerosis still remains unclear. It should not be used

Drug and Therapeutics Bulletin of Navarre (Spain)2011