Latest & greatest articles for pulmonary embolism

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Top results for pulmonary embolism

121. Ultrasound-Assisted Catheter-Directed Thrombolysis in High-Risk and Intermediate-High-Risk Pulmonary Embolism: A Meta-analysis. (Abstract)

Ultrasound-Assisted Catheter-Directed Thrombolysis in High-Risk and Intermediate-High-Risk Pulmonary Embolism: A Meta-analysis. Catheter-directed Ultrasound-Assisted Thrombolysis (USAT) is a novel technology providing a high efficacy with a reduced bleeding risk in patients with pulmonary embolism (PE).We performed a meta-analysis based on presented or published PE series in which USAT was utilized. We searched the MEDLINE, EMBASE and the Cochrane Library for trials published up to December (...) 2015.The primary outcomes were mean pulmonary artery pressure (PAMP), right to left ventricle diameter ratio (RV/LV ratio) and computed tomography (CT) obstruction score. The secondary outcomes were all-cause and cardiovascular mortality, major and minor bleeding episodes and recurrent PE. The 11 trials (n=553) and 15 trials (n=655) met eligibility criteria of primary and secondary outcomes, respectively. USAT was found to significantly reduce PAMP, RV/LV ratio and CT obstruction scores. After

2017 Current vascular pharmacology

122. [Frequency, Cause, and Awareness of Pulmonary Embolism in Oncologic Patients]. (Full text)

[Frequency, Cause, and Awareness of Pulmonary Embolism in Oncologic Patients]. The frequency of pulmonary embolism (PE) in oncologic patients ranges from 1.1 % to 7.3 % depending on whether not only symptomatic findings but also incidental and initially overseen events are considered. The frequency of PE is tumor-specific. Most frequently PE occurs in patients with malignancy of the ovary (25 %), pancreas, brain, uterus, and multiple myeloma. Most rarely is PE found in patients with malignancy

2017 Pneumologie (Stuttgart, Germany) PubMed abstract

123. Response to "Comment on State-of-the-Art Imaging in Pulmonary Embolism: Ventilation/Perfusion Single-Photon Emission Computed Tomography versus Computed Tomography Angiography-Controversies, Results, and Recommendations from a Systematic Review". (Full text)

Response to "Comment on State-of-the-Art Imaging in Pulmonary Embolism: Ventilation/Perfusion Single-Photon Emission Computed Tomography versus Computed Tomography Angiography-Controversies, Results, and Recommendations from a Systematic Review". 28346962 2018 06 22 2018 12 02 1098-9064 43 8 2017 11 Seminars in thrombosis and hemostasis Semin. Thromb. Hemost. Response to "Comment on State-of-the-Art Imaging in Pulmonary Embolism: Ventilation/Perfusion Single-Photon Emission Computed Tomography (...) , Esbjerg, Denmark. Gerke Oke O Department of Nuclear Medicine, Odense University Hospital, Odense C, Denmark. Centre of Health Economics Research, University of Southern Denmark, Odense M, Denmark. Madsen Poul Henning PH Division of Respiratory Medicine, Department of Medicine, Lillebælt Hospital Vejle, Vejle, Denmark. eng Letter Comment 2017 03 27 United States Semin Thromb Hemost 0431155 0094-6176 IM Semin Thromb Hemost. 2017 Nov;43(8):902-903 28219083 Computed Tomography Angiography Humans Pulmonary

2017 Seminars In Thrombosis And Hemostasis PubMed abstract

124. Pulmonary embolism and in situ pulmonary artery thrombosis in paediatrics. A systematic review. (Abstract)

Pulmonary embolism and in situ pulmonary artery thrombosis in paediatrics. A systematic review. Data on paediatric pulmonary embolism (PE) are scarce. We sought to systematically review the current literature on childhood PE and conducted a search on paediatric PE via PubMed (1946-2013) and Embase (1980-2013). There was significant heterogeneity in reported data. Two patterns were noted: classic thromboembolic PE (TE-PE) and in situ pulmonary artery thrombosis (ISPAT). Mean age of presentation

2017 Thrombosis and haemostasis

125. Comment on "State-of-the-Art Imaging in Pulmonary Embolism: Ventilation/Perfusion Single-Photon Emission Computed Tomography versus Computed Tomography Angiography-Controversies, Results, and Recommendations from a Systematic Review". (Full text)

Comment on "State-of-the-Art Imaging in Pulmonary Embolism: Ventilation/Perfusion Single-Photon Emission Computed Tomography versus Computed Tomography Angiography-Controversies, Results, and Recommendations from a Systematic Review". 28219083 2018 06 22 2018 12 02 1098-9064 43 8 2017 11 Seminars in thrombosis and hemostasis Semin. Thromb. Hemost. Comment on "State-of-the-Art Imaging in Pulmonary Embolism: Ventilation/Perfusion Single-Photon Emission Computed Tomography versus Computed (...) Tomography Angiography Humans Pulmonary Embolism Tomography, Emission-Computed, Single-Photon Tomography, X-Ray Computed Disclosure The authors report no conflicts of interest in this work. 2017 2 22 6 0 2018 6 23 6 0 2017 2 21 6 0 ppublish 28219083 10.1055/s-0036-1598006

2017 Seminars In Thrombosis And Hemostasis PubMed abstract

126. Pulmonary Embolism and Atrial Fibrillation: Two Sides of the Same Coin? A Systematic Review. (Abstract)

Pulmonary Embolism and Atrial Fibrillation: Two Sides of the Same Coin? A Systematic Review. Pulmonary embolism (PE) is a common, potentially fatal thrombotic disease. Atrial fibrillation (AF), the most common arrhythmia, may also lead to thromboembolic complications. Although initially appearing as distinct entities, PE and AF may coexist. The direction and extent of this association has not been well characterized. We performed a search of PubMed, Scopus, and the Cochrane Database

2017 Seminars In Thrombosis And Hemostasis

127. Surgical Embolectomy for Acute Pulmonary Embolism: Systematic Review and Comprehensive Meta-Analyses. (Full text)

Surgical Embolectomy for Acute Pulmonary Embolism: Systematic Review and Comprehensive Meta-Analyses. Surgical pulmonary embolectomy (SPE) is a viable treatment approach for subsets of patients with acute pulmonary embolism. However, outcomes data are limited. We sought to characterize mortality and safety outcomes for this population. Studies reporting inhospital mortality for patients undergoing SPE for acute pulmonary embolism were included. In 56 eligible studies, we found 1,579 patients (...) who underwent 1,590 SPE operations. The pooled inhospital all-cause mortality rate was 26.3% (95% confidence interval: 22.5% to 30.5%). Surgical site complications occurred in 7.0% of operations (95% confidence interval: 4.9% to 9.8%). More investigation is required to define the patient population that would benefit the most from SPE.Copyright © 2017 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

2017 The Annals of thoracic surgery PubMed abstract

128. MicroRNAs are novel non-invasive diagnostic biomarkers for pulmonary embolism: a meta-analysis. (Full text)

MicroRNAs are novel non-invasive diagnostic biomarkers for pulmonary embolism: a meta-analysis. The diagnosis of pulmonary embolism (PE) still remains difficult in clinical practice. MicroRNAs (miRNAs) have been widely investigated as biomarkers for various diseases. However, the diagnostic biomarker value of miRNAs in the diagnosis of PE is unclear. Therefore, we conducted this meta-analysis to establish the diagnostic power of miRNAs for PE diagnosis.A systematic literature search in PubMed

2017 Journal of thoracic disease PubMed abstract

129. Age-adjusted D-Dimer to Exclude Pulmonary Embolism

Age-adjusted D-Dimer to Exclude Pulmonary Embolism Emergency Medicine > Journal Club > Archive > February 2016 Toggle navigation February 2016 Age-adjusted D-Dimer to Exclude Pulmonary Embolism Vignette You are working in a community ED one afternoon when you encounter Mrs. X, a pleasant 65-year old woman with a history of hypertension and osteoporosis, who is in town visiting her grandchildren from California. She flew in 2 days earlier, and for the last 12 hours has noted some right-sided (...) in additional confirmatory testing (CT, VQ scan). Search Strategy PubMed was searched using the terms "age adjusted d-dimer" ( ). This resulted in 148 articles, from which the following 4 were selected. Article 1: Article 2: Article 3: Article 4: Bottom Line In patients who are not high-risk for pulmonary embolism, D-dimer has been shown to be effective at ruling out disease. Unfortunately, this test also has a low specificity and a high false-positive risk. This risk increases (and specificity decreases

2017 Washington University Emergency Medicine Journal Club

130. Safety of catheter-directed thrombolysis for massive and submassive pulmonary embolism: Results of a multicenter registry and meta-analysis. (Abstract)

Safety of catheter-directed thrombolysis for massive and submassive pulmonary embolism: Results of a multicenter registry and meta-analysis. To evaluate the safety and efficacy of catheter-directed thrombolysis (CDT) in the treatment of acute pulmonary embolism (PE).The use of CDT for the treatment of acute submassive and massive PE is increasing in frequency. However, its safety and efficacy have not been well elucidated.This study is made of two parts: one is a two-center registry of acute PE (...) patients treated with CDT. The safety outcome evaluated was any major complication including fatal, intracranial (ICH), intraocular, or retroperitoneal hemorrhage or any overt bleeding requiring transfusion or surgical repair. The efficacy outcome was acute change in invasive pulmonary artery systolic pressure (PASP). The second part is a meta-analysis of all contemporary studies that used CDT for PE. Reported outcomes are the same as in the registry, with the addition of right ventricular to left

2017 Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

131. Incidence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a contemporary view of the published literature. (Full text)

Incidence of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: a contemporary view of the published literature. The incidence of chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonary embolism (PE) is relevant for management decisions but is currently unknown.We performed a meta-analysis of studies including consecutive PE patients followed for CTEPH. Study cohorts were predefined as "all comers", "survivors" or "survivors without major comorbidities

2017 European Respiratory Journal PubMed abstract

132. Imaging for the exclusion of pulmonary embolism in pregnancy. (Full text)

Imaging for the exclusion of pulmonary embolism in pregnancy. Pulmonary embolism is a leading cause of pregnancy-related death. An accurate diagnosis in pregnant patients is crucial to prevent untreated pulmonary embolism as well as unnecessary anticoagulant treatment and future preventive measures. Applied imaging techniques might perform differently in these younger patients with less comorbidity and altered physiology, who largely have been excluded from diagnostic studies.To determine (...) the diagnostic accuracy of computed tomography pulmonary angiography (CTPA), lung scintigraphy and magnetic resonance angiography (MRA) for the diagnosis of pulmonary embolism during pregnancy.We searched MEDLINE and Embase until July 2015. We used included studies as seeds in citations searches and in 'find similar' functions and searched reference lists. We approached experts in the field to help us identify non-indexed studies.We included consecutive series of pregnant patients suspected of pulmonary

2017 Cochrane PubMed abstract

133. A meta-analysis of efficacy and safety of catheter-directed interventions in submassive pulmonary embolism. (Abstract)

A meta-analysis of efficacy and safety of catheter-directed interventions in submassive pulmonary embolism. Catheter-directed interventions, such as catheter-directed thrombolysis (CDT), are becoming a popular therapeutic option for patients with hemodynamically stable pulmonary embolism (PE) and right ventricle (RV) dysfunction (submassive PE). We wished to quantitatively assess therapeutic efficacy and safety of catheter-directed interventions in submassive PE.PubMed, Embase, Cochrane (...) and Scopus were searched for studies on catheter-directed interventions and submassive PE. Studies reporting data on therapeutic efficacy (RV to left ventricle [RV/LV] ratio, systolic pulmonary artery pressure) and safety outcomes (in-hospital and 30-day mortality rates, major and minor bleeding rates) were retained and assessed.The final reference sample included 13 publications (11 papers and 2 conference abstracts), collectively enrolling 422 patients with submassive PE. The majority (8/13) studies

2017 European review for medical and pharmacological sciences

134. Pulmonary Embolism Diagnosis and Treatment

a short in-hospital observation period. The recent American College of Chest Physicians Guidelines (2016) suggest treatment at home or early discharge over standard discharge for patients with low-risk PE (2B recommendation). Many physicians still have concerns regarding the outpatient treatment or early discharge of low-risk PE patients (Singer 2016). The purpose of this guideline is five-fold: • Provide an evidence-based approach to the diagnosis and management of acute pulmonary embolism (...) of this guideline, the recommendations for treatment of pulmonary embolism (see p. 9) can also be applied to patients with DVT. Symptoms of pulmonary embolism • Pleuritic chest pain • Shortness of breath • Dyspnea • Tachycardia • Hypoxemia Abbreviations ACCP American College of Chest Physicians PERC Pulmonary Embolism Rule-out Criteria DOACs Direct oral anticoagulants PESI Pulmonary Embolism Severity Index DVT Deep vein thrombosis SSPE Subsegmental pulmonary embolism LMWH Low molecular weight heparin UFH

2017 Kaiser Permanente Clinical Guidelines

139. Thrombolytic therapy for pulmonary embolism and extensive iliofemoral deep vein thrombosis

Thrombolytic therapy for pulmonary embolism and extensive iliofemoral deep vein thrombosis

2017 DynaMed Plus

140. Aplastic anemia and risk of deep vein thrombosis and pulmonary embolism: A nationwide cohort study (Abstract)

Aplastic anemia and risk of deep vein thrombosis and pulmonary embolism: A nationwide cohort study Deep vein thrombosis (DVT) and pulmonary embolism (PE) constitute venous thromboembolism (VTE), which is not fully known in aplastic anemia (AA). Therefore, we investigated the incidence and risk of VTE in AA patients.We conducted a nationwide cohort study to investigate the risk of DVT and PE in patients with AA. We identified patients with newly diagnosed AA as the AA cohort between 2000

2017 EvidenceUpdates