Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4)
Latest & greatest articles for pulmonary embolism
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on pulmonary embolism or other clinical topics then use Trip today.
This page lists the very latest high quality evidence on pulmonary embolism and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.
What is Trip?
Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.
Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.
As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.
For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via firstname.lastname@example.org
Ultrasound-Assisted Catheter-Directed Thrombolysis in High-Risk and Intermediate-High-Risk PulmonaryEmbolism: A Meta-analysis. Catheter-directed Ultrasound-Assisted Thrombolysis (USAT) is a novel technology providing a high efficacy with a reduced bleeding risk in patients with pulmonaryembolism (PE).We performed a meta-analysis based on presented or published PE series in which USAT was utilized. We searched the MEDLINE, EMBASE and the Cochrane Library for trials published up to December (...) 2015.The primary outcomes were mean pulmonary artery pressure (PAMP), right to left ventricle diameter ratio (RV/LV ratio) and computed tomography (CT) obstruction score. The secondary outcomes were all-cause and cardiovascular mortality, major and minor bleeding episodes and recurrent PE. The 11 trials (n=553) and 15 trials (n=655) met eligibility criteria of primary and secondary outcomes, respectively. USAT was found to significantly reduce PAMP, RV/LV ratio and CT obstruction scores. After
[Frequency, Cause, and Awareness of PulmonaryEmbolism in Oncologic Patients]. The frequency of pulmonaryembolism (PE) in oncologic patients ranges from 1.1 % to 7.3 % depending on whether not only symptomatic findings but also incidental and initially overseen events are considered. The frequency of PE is tumor-specific. Most frequently PE occurs in patients with malignancy of the ovary (25 %), pancreas, brain, uterus, and multiple myeloma. Most rarely is PE found in patients with malignancy
Response to "Comment on State-of-the-Art Imaging in PulmonaryEmbolism: Ventilation/Perfusion Single-Photon Emission Computed Tomography versus Computed Tomography Angiography-Controversies, Results, and Recommendations from a Systematic Review". 28346962 2018 06 22 2018 12 02 1098-9064 43 8 2017 11 Seminars in thrombosis and hemostasis Semin. Thromb. Hemost. Response to "Comment on State-of-the-Art Imaging in PulmonaryEmbolism: Ventilation/Perfusion Single-Photon Emission Computed Tomography (...) , Esbjerg, Denmark. Gerke Oke O Department of Nuclear Medicine, Odense University Hospital, Odense C, Denmark. Centre of Health Economics Research, University of Southern Denmark, Odense M, Denmark. Madsen Poul Henning PH Division of Respiratory Medicine, Department of Medicine, Lillebælt Hospital Vejle, Vejle, Denmark. eng Letter Comment 2017 03 27 United States Semin Thromb Hemost 0431155 0094-6176 IM Semin Thromb Hemost. 2017 Nov;43(8):902-903 28219083 Computed Tomography Angiography Humans Pulmonary
Pulmonaryembolism and in situ pulmonary artery thrombosis in paediatrics. A systematic review. Data on paediatric pulmonaryembolism (PE) are scarce. We sought to systematically review the current literature on childhood PE and conducted a search on paediatric PE via PubMed (1946-2013) and Embase (1980-2013). There was significant heterogeneity in reported data. Two patterns were noted: classic thromboembolic PE (TE-PE) and in situ pulmonary artery thrombosis (ISPAT). Mean age of presentation
PulmonaryEmbolism and Atrial Fibrillation: Two Sides of the Same Coin? A Systematic Review. Pulmonaryembolism (PE) is a common, potentially fatal thrombotic disease. Atrial fibrillation (AF), the most common arrhythmia, may also lead to thromboembolic complications. Although initially appearing as distinct entities, PE and AF may coexist. The direction and extent of this association has not been well characterized. We performed a search of PubMed, Scopus, and the Cochrane Database
MicroRNAs are novel non-invasive diagnostic biomarkers for pulmonaryembolism: a meta-analysis. The diagnosis of pulmonaryembolism (PE) still remains difficult in clinical practice. MicroRNAs (miRNAs) have been widely investigated as biomarkers for various diseases. However, the diagnostic biomarker value of miRNAs in the diagnosis of PE is unclear. Therefore, we conducted this meta-analysis to establish the diagnostic power of miRNAs for PE diagnosis.A systematic literature search in PubMed
Age-adjusted D-Dimer to Exclude PulmonaryEmbolism Emergency Medicine > Journal Club > Archive > February 2016 Toggle navigation February 2016 Age-adjusted D-Dimer to Exclude PulmonaryEmbolism Vignette You are working in a community ED one afternoon when you encounter Mrs. X, a pleasant 65-year old woman with a history of hypertension and osteoporosis, who is in town visiting her grandchildren from California. She flew in 2 days earlier, and for the last 12 hours has noted some right-sided (...) in additional confirmatory testing (CT, VQ scan). Search Strategy PubMed was searched using the terms "age adjusted d-dimer" ( ). This resulted in 148 articles, from which the following 4 were selected. Article 1: Article 2: Article 3: Article 4: Bottom Line In patients who are not high-risk for pulmonaryembolism, D-dimer has been shown to be effective at ruling out disease. Unfortunately, this test also has a low specificity and a high false-positive risk. This risk increases (and specificity decreases
Safety of catheter-directed thrombolysis for massive and submassive pulmonaryembolism: Results of a multicenter registry and meta-analysis. To evaluate the safety and efficacy of catheter-directed thrombolysis (CDT) in the treatment of acute pulmonaryembolism (PE).The use of CDT for the treatment of acute submassive and massive PE is increasing in frequency. However, its safety and efficacy have not been well elucidated.This study is made of two parts: one is a two-center registry of acute PE (...) patients treated with CDT. The safety outcome evaluated was any major complication including fatal, intracranial (ICH), intraocular, or retroperitoneal hemorrhage or any overt bleeding requiring transfusion or surgical repair. The efficacy outcome was acute change in invasive pulmonary artery systolic pressure (PASP). The second part is a meta-analysis of all contemporary studies that used CDT for PE. Reported outcomes are the same as in the registry, with the addition of right ventricular to left
Incidence of chronic thromboembolic pulmonary hypertension after acute pulmonaryembolism: a contemporary view of the published literature. The incidence of chronic thromboembolic pulmonary hypertension (CTEPH) after pulmonaryembolism (PE) is relevant for management decisions but is currently unknown.We performed a meta-analysis of studies including consecutive PE patients followed for CTEPH. Study cohorts were predefined as "all comers", "survivors" or "survivors without major comorbidities
Imaging for the exclusion of pulmonaryembolism in pregnancy. Pulmonaryembolism is a leading cause of pregnancy-related death. An accurate diagnosis in pregnant patients is crucial to prevent untreated pulmonaryembolism as well as unnecessary anticoagulant treatment and future preventive measures. Applied imaging techniques might perform differently in these younger patients with less comorbidity and altered physiology, who largely have been excluded from diagnostic studies.To determine (...) the diagnostic accuracy of computed tomography pulmonary angiography (CTPA), lung scintigraphy and magnetic resonance angiography (MRA) for the diagnosis of pulmonaryembolism during pregnancy.We searched MEDLINE and Embase until July 2015. We used included studies as seeds in citations searches and in 'find similar' functions and searched reference lists. We approached experts in the field to help us identify non-indexed studies.We included consecutive series of pregnant patients suspected of pulmonary
A meta-analysis of efficacy and safety of catheter-directed interventions in submassive pulmonaryembolism. Catheter-directed interventions, such as catheter-directed thrombolysis (CDT), are becoming a popular therapeutic option for patients with hemodynamically stable pulmonaryembolism (PE) and right ventricle (RV) dysfunction (submassive PE). We wished to quantitatively assess therapeutic efficacy and safety of catheter-directed interventions in submassive PE.PubMed, Embase, Cochrane (...) and Scopus were searched for studies on catheter-directed interventions and submassive PE. Studies reporting data on therapeutic efficacy (RV to left ventricle [RV/LV] ratio, systolic pulmonary artery pressure) and safety outcomes (in-hospital and 30-day mortality rates, major and minor bleeding rates) were retained and assessed.The final reference sample included 13 publications (11 papers and 2 conference abstracts), collectively enrolling 422 patients with submassive PE. The majority (8/13) studies
a short in-hospital observation period. The recent American College of Chest Physicians Guidelines (2016) suggest treatment at home or early discharge over standard discharge for patients with low-risk PE (2B recommendation). Many physicians still have concerns regarding the outpatient treatment or early discharge of low-risk PE patients (Singer 2016). The purpose of this guideline is five-fold: • Provide an evidence-based approach to the diagnosis and management of acute pulmonaryembolism (...) of this guideline, the recommendations for treatment of pulmonaryembolism (see p. 9) can also be applied to patients with DVT. Symptoms of pulmonaryembolism • Pleuritic chest pain • Shortness of breath • Dyspnea • Tachycardia • Hypoxemia Abbreviations ACCP American College of Chest Physicians PERC PulmonaryEmbolism Rule-out Criteria DOACs Direct oral anticoagulants PESI PulmonaryEmbolism Severity Index DVT Deep vein thrombosis SSPE Subsegmental pulmonaryembolism LMWH Low molecular weight heparin UFH
Aplastic anemia and risk of deep vein thrombosis and pulmonaryembolism: A nationwide cohort study Deep vein thrombosis (DVT) and pulmonaryembolism (PE) constitute venous thromboembolism (VTE), which is not fully known in aplastic anemia (AA). Therefore, we investigated the incidence and risk of VTE in AA patients.We conducted a nationwide cohort study to investigate the risk of DVT and PE in patients with AA. We identified patients with newly diagnosed AA as the AA cohort between 2000