Latest & greatest articles for pulmonary embolism

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Top results for pulmonary embolism

61. Imaging for the exclusion of pulmonary embolism in pregnancy. Full Text available with Trip Pro

Imaging for the exclusion of pulmonary embolism in pregnancy. Pulmonary embolism is a leading cause of pregnancy-related death. An accurate diagnosis in pregnant patients is crucial to prevent untreated pulmonary embolism as well as unnecessary anticoagulant treatment and future preventive measures. Applied imaging techniques might perform differently in these younger patients with less comorbidity and altered physiology, who largely have been excluded from diagnostic studies.To determine (...) the diagnostic accuracy of computed tomography pulmonary angiography (CTPA), lung scintigraphy and magnetic resonance angiography (MRA) for the diagnosis of pulmonary embolism during pregnancy.We searched MEDLINE and Embase until July 2015. We used included studies as seeds in citations searches and in 'find similar' functions and searched reference lists. We approached experts in the field to help us identify non-indexed studies.We included consecutive series of pregnant patients suspected of pulmonary

2017 Cochrane

62. Pulmonary Embolism Diagnosis and Treatment

a short in-hospital observation period. The recent American College of Chest Physicians Guidelines (2016) suggest treatment at home or early discharge over standard discharge for patients with low-risk PE (2B recommendation). Many physicians still have concerns regarding the outpatient treatment or early discharge of low-risk PE patients (Singer 2016). The purpose of this guideline is five-fold: • Provide an evidence-based approach to the diagnosis and management of acute pulmonary embolism (...) of this guideline, the recommendations for treatment of pulmonary embolism (see p. 9) can also be applied to patients with DVT. Symptoms of pulmonary embolism • Pleuritic chest pain • Shortness of breath • Dyspnea • Tachycardia • Hypoxemia Abbreviations ACCP American College of Chest Physicians PERC Pulmonary Embolism Rule-out Criteria DOACs Direct oral anticoagulants PESI Pulmonary Embolism Severity Index DVT Deep vein thrombosis SSPE Subsegmental pulmonary embolism LMWH Low molecular weight heparin UFH

2017 Kaiser Permanente Clinical Guidelines

67. Thrombolytic therapy for pulmonary embolism and extensive iliofemoral deep vein thrombosis

Thrombolytic therapy for pulmonary embolism and extensive iliofemoral deep vein thrombosis

2017 DynaMed Plus

68. Aplastic anemia and risk of deep vein thrombosis and pulmonary embolism: A nationwide cohort study (Abstract)

Aplastic anemia and risk of deep vein thrombosis and pulmonary embolism: A nationwide cohort study Deep vein thrombosis (DVT) and pulmonary embolism (PE) constitute venous thromboembolism (VTE), which is not fully known in aplastic anemia (AA). Therefore, we investigated the incidence and risk of VTE in AA patients.We conducted a nationwide cohort study to investigate the risk of DVT and PE in patients with AA. We identified patients with newly diagnosed AA as the AA cohort between 2000

2017 EvidenceUpdates

69. Deep Vein Thrombosis in Patients with Pulmonary Embolism: Prevalance, Clinical Significance and Outcome Full Text available with Trip Pro

Deep Vein Thrombosis in Patients with Pulmonary Embolism: Prevalance, Clinical Significance and Outcome Deep venous thrombosis (DVT) and pulmonary embolism (PE) are considered as similar disease entities representing different clinical manifestations. The objectives of this study were: 1) to determine the prevalence and outcome of DVT in patients with PE; 2) to identify additional risk factors for PE-related unfavorable outcome and 30-day all-cause mortality; and 3) to establish the clinical

2016 Vascular specialist international

70. Subacute right heart failure revealing three simultaneous causes of post‐embolic pulmonary hypertension in metastatic dissemination of breast cancer Full Text available with Trip Pro

Subacute right heart failure revealing three simultaneous causes of post‐embolic pulmonary hypertension in metastatic dissemination of breast cancer A 72-year-old woman with history of breast cancer only treated surgically was referred to our department for pulmonary hypertension (PH) suspicion. Echocardiogram revealed elevated right ventricular systolic pressure. Computed tomography (CT) angiogram showed no pulmonary embolism (PE), but lung scan revealed two ventilation-perfusion mismatch (...) areas. Right cardiac catheterization established precapillary PH. Despite treatment with PH specific therapy (sildenafil, ambrisentan, and epoprostenol), her condition worsened rapidly with acute right heart failure (RHF). She died 22 days after admission. Post-mortem microscopic examination showed a rare combination of PH etiologies consistent with metastasis of breast cancer in pulmonary vasculature including the rare pulmonary tumour thrombotic microangiopathy (PTTM).

2016 ESC heart failure

71. Risk stratifying emergency department patients with acute pulmonary embolism: Does the simplified Pulmonary Embolism Severity Index perform as well as the original? (Abstract)

Risk stratifying emergency department patients with acute pulmonary embolism: Does the simplified Pulmonary Embolism Severity Index perform as well as the original? The Pulmonary Embolism Severity Index (PESI) is a validated prognostic score to estimate the 30-day mortality of emergency department (ED) patients with acute pulmonary embolism (PE). A simplified version (sPESI) was derived but has not been as well studied in the U.S. We sought to validate both indices in a community hospital

2016 EvidenceUpdates

72. Acute pulmonary embolism: mortality prediction by the 2014 European Society of Cardiology risk stratification model Full Text available with Trip Pro

Acute pulmonary embolism: mortality prediction by the 2014 European Society of Cardiology risk stratification model The European Society of Cardiology (ESC) has proposed an updated risk stratification model for death in patients with acute pulmonary embolism based on clinical scores (Pulmonary Embolism Severity Index (PESI) or simplified PESI (sPESI)), right ventricle dysfunction (RVD) and elevated serum troponin (2014 ESC model).We assessed the ability of the 2014 ESC model to predict 30-day (...) death after acute pulmonary embolism. Consecutive patients with symptomatic, confirmed pulmonary embolism included in prospective cohorts were merged in a collaborative database. Patients' risk was classified as high (shock or hypotension), intermediate-high (RVD and elevated troponin), intermediate-low (RVD or increased troponin or none) and low (sPESI 0). Study outcomes were death and pulmonary embolism-related death at 30 days.Among 906 patients (mean±sd age 68±16, 489 females), death

2016 EvidenceUpdates

73. The High Risk of Contrast-induced Nephropathy in Patients with Suspected Pulmonary Embolism Despite Three Different Prophylaxis: A Randomized Controlled Trial Full Text available with Trip Pro

The High Risk of Contrast-induced Nephropathy in Patients with Suspected Pulmonary Embolism Despite Three Different Prophylaxis: A Randomized Controlled Trial The objective was to compare the protective effects of N-acetylcysteine (NAC) plus normal saline (NS), sodium bicarbonate (NaHCO3 ) plus NS, and NS alone in the prevention of contrast-induced nephropathy (CIN) after computed tomography pulmonary angiography (CTPA) in emergency patients.This study was planned as a randomized, controlled (...) clinical research. Patients undergoing contrast-enhanced CTPA on suspicion of pulmonary embolism (PE) in the emergency department and with at least one risk factor for development of CIN were included in one of three different prophylaxis groups. The groups received 3 mL/kg intravenous (IV) NAC+NS or NaHCO3 +NS solution or NS alone 1 hour before CTPA and 1 mL/kg IV per hour for a minimum of 6 hours after CTPA. CIN was evaluated as the primary outcome and moderate or severe renal insufficiency

2016 EvidenceUpdates

74. Addendum to Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol

,kf. 21 or/15-20 22 Positron-Emission Tomography/ 23 (PET adj4 (scan* or imag*)).ti,ab,kf. 24 (FDGPET or FDG PET or PETCT or PET CT or positron).ti,ab,kf. 25 or/22-24 26 exp Lung/us 27 exp Ultrasonography/ 28 (ultrasound or sonogra* or ultrasonic or ultrasonogra* or echotomogra* or echogra* or doppler).ti,ab,kf. 29 or/27-28 30 exp lung/ 31 (lung or lungs or thoracic or thorax or chest).ti,ab,kf. 32 or/30-31 33 29 and 32 34 exp Echocardiography/ 35 (cardiac echo* or heart echo* or echocardiogra (...) or "v/q" or "V/P" or VP or V-P) adj4 (imag* or scan* or SPECT)).ti,ab,kw. 61 or/55-60 62 positron emission tomography/ 63 (PET adj4 (scan* or imag*)).ti,ab,kw. 64 (FDGPET or FDG PET or PETCT or PET CT or positron).ti,ab,kw. 65 or/62-64 66 exp echography/ 67 (ultrasound or sonogra* or ultrasonic or ultrasonogra* or echotomogra* or echogra* or doppler).ti,ab,kw. 68 or/66-67 69 exp lung/ 70 (lung or lungs or thoracic or thorax or chest).ti,ab,kw. 71 or/69-70 72 68 and 71 73 (cardiac echo* or heart echo

2016 CADTH - Optimal Use

75. Addendum to Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol

,kf. 21 or/15-20 22 Positron-Emission Tomography/ 23 (PET adj4 (scan* or imag*)).ti,ab,kf. 24 (FDGPET or FDG PET or PETCT or PET CT or positron).ti,ab,kf. 25 or/22-24 26 exp Lung/us 27 exp Ultrasonography/ 28 (ultrasound or sonogra* or ultrasonic or ultrasonogra* or echotomogra* or echogra* or doppler).ti,ab,kf. 29 or/27-28 30 exp lung/ 31 (lung or lungs or thoracic or thorax or chest).ti,ab,kf. 32 or/30-31 33 29 and 32 34 exp Echocardiography/ 35 (cardiac echo* or heart echo* or echocardiogra (...) or "v/q" or "V/P" or VP or V-P) adj4 (imag* or scan* or SPECT)).ti,ab,kw. 61 or/55-60 62 positron emission tomography/ 63 (PET adj4 (scan* or imag*)).ti,ab,kw. 64 (FDGPET or FDG PET or PETCT or PET CT or positron).ti,ab,kw. 65 or/62-64 66 exp echography/ 67 (ultrasound or sonogra* or ultrasonic or ultrasonogra* or echotomogra* or echogra* or doppler).ti,ab,kw. 68 or/66-67 69 exp lung/ 70 (lung or lungs or thoracic or thorax or chest).ti,ab,kw. 71 or/69-70 72 68 and 71 73 (cardiac echo* or heart echo

2016 CADTH - Optimal Use

76. Prevalence of Pulmonary Embolism among Patients Hospitalized for Syncope. Full Text available with Trip Pro

Prevalence of Pulmonary Embolism among Patients Hospitalized for Syncope. The prevalence of pulmonary embolism among patients hospitalized for syncope is not well documented, and current guidelines pay little attention to a diagnostic workup for pulmonary embolism in these patients.We performed a systematic workup for pulmonary embolism in patients admitted to 11 hospitals in Italy for a first episode of syncope, regardless of whether there were alternative explanations for the syncope (...) . The diagnosis of pulmonary embolism was ruled out in patients who had a low pretest clinical probability, which was defined according to the Wells score, in combination with a negative d-dimer assay. In all other patients, computed tomographic pulmonary angiography or ventilation-perfusion lung scanning was performed.A total of 560 patients (mean age, 76 years) were included in the study. A diagnosis of pulmonary embolism was ruled out in 330 of the 560 patients (58.9%) on the basis of the combination

2016 NEJM

77. Treatment of acute pulmonary embolism with dabigatran versus warfarin. A pooled analysis of data from RE-COVER and RE-COVER II Full Text available with Trip Pro

Treatment of acute pulmonary embolism with dabigatran versus warfarin. A pooled analysis of data from RE-COVER and RE-COVER II Dabigatran was non-inferior to warfarin for prevention of recurrent venous thromboembolism (VTE), and dabigatran had a lower rate of bleeding compared with warfarin in two large-scale randomised trials, RE-COVER and RE-COVER II. In this study, we investigate the efficacy and safety of dabigatran versus warfarin according to the index event that qualified the patient (...) for enrollment, either symptomatic pulmonary embolism (PE) with or without deep-vein thrombosis (DVT), or DVT alone. We then analyse the anticoagulant effect of dabigatran vs warfarin on patients enrolled with PE. The pooled dataset for the efficacy analysis consisted of 2553 and 2554 patients who were randomised to dabigatran and warfarin, respectively. Recurrent VTE/VTE-related death during the study period and additional 30-day follow-up occurred in 2.7 % of all patients on dabigatran and in 2.4

2016 EvidenceUpdates Controlled trial quality: uncertain

78. Percutaneous mechanical thrombectomy for pulmonary embolism

Percutaneous mechanical thrombectomy for pulmonary embolism Percutaneous mechanical thrombectomy for pulmonary embolism Percutaneous mechanical thrombectomy for pulmonary embolism HAYES, Inc. Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc.. Percutaneous mechanical thrombectomy for pulmonary embolism. Lansdale: HAYES, Inc.. Directory Publication. 2016 (...) alone has failed or is contraindicated. However, the technology is invasive and relatively new, warranting assessment of effectiveness, safety, and the performance of the different commercially available devices. Relevant Questions: For patients with pulmonary embolism (PE), is PMT effective for eliminating thromboses and emboli, restoring blood flow and vascular function, and preventing damage to tissues and organs? Are PMT devices safe? How do PMT devices compare with other standard treatments

2016 Health Technology Assessment (HTA) Database.

79. Optimal Diagnosis for Suspected Acute Pulmonary Embolism

, SPECT/CT, Single-Photon, Tomography Scanners, V/Q scan, Wells, X-Ray Computed, cardiac echo, d-dimer, lung embolism, pulmonary embolism rule out criteria, thoracic ultrasound, ventilation-perfusion scan, ventilation/perfusion scan Optimal Use Report In Brief PUBLISHED : March 2018 Optimal Use Report Recommendations PUBLISHED : March 2018 Optimal Use Report Infographic PUBLISHED : August 2018 Optimal Use Report Science Report PUBLISHED : January 2018 Optimal Strategies for the Diagnosis of Acute (...) Optimal Diagnosis for Suspected Acute Pulmonary Embolism Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism | CADTH.ca Find the information you need Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism Published on: March 1, 2018 Project Number: OP0528-000 Product Line: Research Type: Other Diagnostics Result type: Report Pulmonary embolism (PE) is a blockage of one of the arteries in the lung, frequently

2016 CADTH - Optimal Use

80. Optimal Imaging for Suspected Acute Pulmonary Embolism

, SPECT/CT, Single-Photon, Tomography Scanners, V/Q scan, Wells, X-Ray Computed, cardiac echo, d-dimer, lung embolism, pulmonary embolism rule out criteria, thoracic ultrasound, ventilation-perfusion scan, ventilation/perfusion scan Optimal Use Report In Brief PUBLISHED : March 2018 Optimal Use Report Recommendations PUBLISHED : March 2018 Optimal Use Report Infographic PUBLISHED : August 2018 Optimal Use Report Science Report PUBLISHED : January 2018 Optimal Strategies for the Diagnosis of Acute (...) Optimal Imaging for Suspected Acute Pulmonary Embolism Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism | CADTH.ca Find the information you need Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism Published on: March 1, 2018 Project Number: OP0528-000 Product Line: Research Type: Other Diagnostics Result type: Report Pulmonary embolism (PE) is a blockage of one of the arteries in the lung, frequently

2016 CADTH - Optimal Use