Latest & greatest articles for pulmonary embolism

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Top results for pulmonary embolism

41. Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study.

Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study. BACKGROUND: Validated diagnostic algorithms in patients with suspected pulmonary embolism are often not used correctly or only benefit subgroups of patients, leading to overuse of computed tomography pulmonary angiography (CTPA). The YEARS clinical decision rule that incorporates differential D-dimer cutoff values at presentation, has been developed to be fast (...) , to be compatible with clinical practice, and to reduce the number of CTPA investigations in all age groups. We aimed to prospectively evaluate this novel and simplified diagnostic algorithm for suspected acute pulmonary embolism. METHODS: We did a prospective, multicentre, cohort study in 12 hospitals in the Netherlands, including consecutive patients with suspected pulmonary embolism between Oct 5, 2013, to July 9, 2015. Patients were managed by simultaneous assessment of the YEARS clinical decision rule

Lancet2017

42. Update: D-dimer Test for Excluding the Diagnosis of Pulmonary Embolism

Update: D-dimer Test for Excluding the Diagnosis of Pulmonary Embolism DEFINE_ME_WA This site requires Cookies to be enabled to function. Please ensure Cookies are turned on and then re-visit the desired page.

Annals of Emergency Medicine Systematic Review Snapshots2017

43. Age-adjusted D-Dimer to Exclude Pulmonary Embolism

Age-adjusted D-Dimer to Exclude Pulmonary Embolism Emergency Medicine > Journal Club > Archive > February 2016 Toggle navigation February 2016 Age-adjusted D-Dimer to Exclude Pulmonary Embolism Vignette You are working in a community ED one afternoon when you encounter Mrs. X, a pleasant 65-year old woman with a history of hypertension and osteoporosis, who is in town visiting her grandchildren from California. She flew in 2 days earlier, and for the last 12 hours has noted some right-sided (...) , pleuritic chest pain. She thinks she pulled a muscle picking up her 3-year old grandson, but was worried and wanted to be evaluated. Her physical exam is unremarkable, including a heart rate of 70, a normal oxygen saturation on room air, and a normal respiratory rate. Her lungs are clear and she does seem to have pain with deep inspiration. There is no chest wall tenderness, no LE swelling, no LE cords, and no calf tenderness. Given her recent plane trip you are concerned about a possible PE. Having

Washington University Emergency Medicine Journal Club2017

44. Imaging for the exclusion of pulmonary embolism in pregnancy.

Imaging for the exclusion of pulmonary embolism in pregnancy. BACKGROUND: Pulmonary embolism is a leading cause of pregnancy-related death. An accurate diagnosis in pregnant patients is crucial to prevent untreated pulmonary embolism as well as unnecessary anticoagulant treatment and future preventive measures. Applied imaging techniques might perform differently in these younger patients with less comorbidity and altered physiology, who largely have been excluded from diagnostic studies (...) . OBJECTIVES: To determine the diagnostic accuracy of computed tomography pulmonary angiography (CTPA), lung scintigraphy and magnetic resonance angiography (MRA) for the diagnosis of pulmonary embolism during pregnancy. SEARCH METHODS: We searched MEDLINE and Embase until July 2015. We used included studies as seeds in citations searches and in 'find similar' functions and searched reference lists. We approached experts in the field to help us identify non-indexed studies. SELECTION CRITERIA: We included

Cochrane2017

45. Aplastic anemia and risk of deep vein thrombosis and pulmonary embolism: A nationwide cohort study

Aplastic anemia and risk of deep vein thrombosis and pulmonary embolism: A nationwide cohort study 27923178 2016 12 06 2017 04 13 2017 04 13 1879-2472 149 2017 Jan Thrombosis research Thromb. Res. Aplastic anemia and risk of deep vein thrombosis and pulmonary embolism: A nationwide cohort study. 70-75 S0049-3848(16)30629-6 10.1016/j.thromres.2016.11.017 Deep vein thrombosis (DVT) and pulmonary embolism (PE) constitute venous thromboembolism (VTE), which is not fully known in aplastic anemia (AA (...) ). Therefore, we investigated the incidence and risk of VTE in AA patients. We conducted a nationwide cohort study to investigate the risk of DVT and PE in patients with AA. We identified patients with newly diagnosed AA as the AA cohort between 2000 and 2010 from the National Health Insurance Research Database (NHIRD). The initial admission date for AA diagnosis was set as the index date. For each patient with AA, 4 patients without a history of AA, frequency matched by sex, age (every 5-y span), and year

EvidenceUpdates2017

51. Thrombolytic therapy for pulmonary embolism and extensive iliofemoral deep vein thrombosis

Thrombolytic therapy for pulmonary embolism and extensive iliofemoral deep vein thrombosis

DynaMed Plus2017

52. Deep Vein Thrombosis in Patients with Pulmonary Embolism: Prevalance, Clinical Significance and Outcome

Deep Vein Thrombosis in Patients with Pulmonary Embolism: Prevalance, Clinical Significance and Outcome 28042556 2018 11 13 2288-7970 32 4 2016 Dec Vascular specialist international Vasc Specialist Int Deep Vein Thrombosis in Patients with Pulmonary Embolism: Prevalance, Clinical Significance and Outcome. 166-174 10.5758/vsi.2016.32.4.166 Deep venous thrombosis (DVT) and pulmonary embolism (PE) are considered as similar disease entities representing different clinical manifestations (...) . The objectives of this study were: 1) to determine the prevalence and outcome of DVT in patients with PE; 2) to identify additional risk factors for PE-related unfavorable outcome and 30-day all-cause mortality; and 3) to establish the clinical importance of screening for concomitant DVT. From January 2013 to December 2015, a total of 141 patients with confirmed PE were evaluated. The prevalence and outcome of DVT in patients with PE was determined. Furthermore, the potential risk factors for PE-related

Vascular specialist international2016 Full Text: Link to full Text with Trip Pro

53. Subacute right heart failure revealing three simultaneous causes of post‐embolic pulmonary hypertension in metastatic dissemination of breast cancer

Subacute right heart failure revealing three simultaneous causes of post‐embolic pulmonary hypertension in metastatic dissemination of breast cancer 28217316 2018 11 13 2055-5822 4 1 2017 Feb ESC heart failure ESC Heart Fail Subacute right heart failure revealing three simultaneous causes of post-embolic pulmonary hypertension in metastatic dissemination of breast cancer. 75-77 10.1002/ehf2.12106 A 72-year-old woman with history of breast cancer only treated surgically was referred to our (...) department for pulmonary hypertension (PH) suspicion. Echocardiogram revealed elevated right ventricular systolic pressure. Computed tomography (CT) angiogram showed no pulmonary embolism (PE), but lung scan revealed two ventilation-perfusion mismatch areas. Right cardiac catheterization established precapillary PH. Despite treatment with PH specific therapy (sildenafil, ambrisentan, and epoprostenol), her condition worsened rapidly with acute right heart failure (RHF). She died 22 days after admission

ESC heart failure2016 Full Text: Link to full Text with Trip Pro

54. Risk stratifying emergency department patients with acute pulmonary embolism: Does the simplified Pulmonary Embolism Severity Index perform as well as the original?

Risk stratifying emergency department patients with acute pulmonary embolism: Does the simplified Pulmonary Embolism Severity Index perform as well as the original? 27764729 2016 10 20 2017 04 17 2017 04 17 1879-2472 148 2016 Dec Thrombosis research Thromb. Res. Risk stratifying emergency department patients with acute pulmonary embolism: Does the simplified Pulmonary Embolism Severity Index perform as well as the original? 1-8 S0049-3848(16)30558-8 10.1016/j.thromres.2016.09.023 The Pulmonary Embolism (...) Severity Index (PESI) is a validated prognostic score to estimate the 30-day mortality of emergency department (ED) patients with acute pulmonary embolism (PE). A simplified version (sPESI) was derived but has not been as well studied in the U.S. We sought to validate both indices in a community hospital setting in the U.S. and compare their performance in predicting 30-day all-cause mortality and classification of cases into low-risk and higher-risk categories. This retrospective cohort study included

EvidenceUpdates2016

55. Pulmonary Embolism Imaging in Canada

Pulmonary Embolism Imaging in Canada Pulmonary Embolism Imaging in Canada | CADTH.ca Find the information you need Pulmonary Embolism Imaging in Canada Pulmonary Embolism Imaging in Canada Published on: November 8, 2016 Project Number: ES0307-000 Product Line: Result type: Report Projects listed as “in progress” are at various stages and points of completion. These products have different processes and timelines; therefore, the timing of posting of the final reports varies. . The “Projects (...) in Progress” page on the CADTH website is updated on a seven- to eight-day cycle. Please be advised that there may be overlap between when a new report is posted online and when the section is updated. . CADTH is undertaking an environmental scan to identify and summarize information regarding pulmonary embolism (PE) imaging in Canada. The scan will describe current practice, challenges, and enablers in diagnosing PE, and the availability of tests, scans, and tools for diagnosing PE. The key objectives

Canadian Agency for Drugs and Technologies in Health - Environmental Scanning2016

56. The High Risk of Contrast-induced Nephropathy in Patients with Suspected Pulmonary Embolism Despite Three Different Prophylaxis: A Randomized Controlled Trial

The High Risk of Contrast-induced Nephropathy in Patients with Suspected Pulmonary Embolism Despite Three Different Prophylaxis: A Randomized Controlled Trial 27411777 2016 09 27 2016 10 07 1553-2712 23 10 2016 Oct Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med The High Risk of Contrast-induced Nephropathy in Patients with Suspected Pulmonary Embolism Despite Three Different Prophylaxis: A Randomized Controlled Trial. 1136-1145 (...) 10.1111/acem.13051 The objective was to compare the protective effects of N-acetylcysteine (NAC) plus normal saline (NS), sodium bicarbonate (NaHCO3 ) plus NS, and NS alone in the prevention of contrast-induced nephropathy (CIN) after computed tomography pulmonary angiography (CTPA) in emergency patients. This study was planned as a randomized, controlled clinical research. Patients undergoing contrast-enhanced CTPA on suspicion of pulmonary embolism (PE) in the emergency department and with at least

EvidenceUpdates2016

57. Acute pulmonary embolism: mortality prediction by the 2014 European Society of Cardiology risk stratification model

Acute pulmonary embolism: mortality prediction by the 2014 European Society of Cardiology risk stratification model 27174887 2016 09 01 2016 09 01 1399-3003 48 3 2016 Sep The European respiratory journal Eur. Respir. J. Acute pulmonary embolism: mortality prediction by the 2014 European Society of Cardiology risk stratification model. 780-6 10.1183/13993003.00024-2016 The European Society of Cardiology (ESC) has proposed an updated risk stratification model for death in patients with acute (...) pulmonary embolism based on clinical scores (Pulmonary Embolism Severity Index (PESI) or simplified PESI (sPESI)), right ventricle dysfunction (RVD) and elevated serum troponin (2014 ESC model).We assessed the ability of the 2014 ESC model to predict 30-day death after acute pulmonary embolism. Consecutive patients with symptomatic, confirmed pulmonary embolism included in prospective cohorts were merged in a collaborative database. Patients' risk was classified as high (shock or hypotension

EvidenceUpdates2016

58. Addendum to Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol

Addendum to Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol Addendum to Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol | CADTH.ca CADTH Document Viewer Addendum to Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol Table of Contents Search this document Addendum to Optimal Strategies (...) for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol October 2016 Ethics Review This protocol was written a priori and will be followed throughout the review process. There are two broad normative questions to consider regarding diagnosis of acute pulmonary embolism (PE): Should we provide diagnosis of acute PE? If yes, which strategies should be provided, and how best should those strategies be provided to diagnose those with acute PE? Both of these questions

CADTH - Optimal Use2016

59. Addendum to Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol

Addendum to Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol Addendum to Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol | CADTH.ca CADTH Document Viewer Addendum to Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol Table of Contents Search this document Addendum to Optimal Strategies (...) for the Diagnosis of Acute Pulmonary Embolism: A Health Technology Assessment – Project Protocol October 2016 Ethics Review This protocol was written a priori and will be followed throughout the review process. There are two broad normative questions to consider regarding diagnosis of acute pulmonary embolism (PE): Should we provide diagnosis of acute PE? If yes, which strategies should be provided, and how best should those strategies be provided to diagnose those with acute PE? Both of these questions

CADTH - Optimal Use2016

60. Prevalence of Pulmonary Embolism among Patients Hospitalized for Syncope.

Prevalence of Pulmonary Embolism among Patients Hospitalized for Syncope. BACKGROUND: The prevalence of pulmonary embolism among patients hospitalized for syncope is not well documented, and current guidelines pay little attention to a diagnostic workup for pulmonary embolism in these patients. METHODS: We performed a systematic workup for pulmonary embolism in patients admitted to 11 hospitals in Italy for a first episode of syncope, regardless of whether there were alternative explanations (...) for the syncope. The diagnosis of pulmonary embolism was ruled out in patients who had a low pretest clinical probability, which was defined according to the Wells score, in combination with a negative d-dimer assay. In all other patients, computed tomographic pulmonary angiography or ventilation-perfusion lung scanning was performed. RESULTS: A total of 560 patients (mean age, 76 years) were included in the study. A diagnosis of pulmonary embolism was ruled out in 330 of the 560 patients (58.9%) on the basis

NEJM2016