Latest & greatest articles for pulmonary embolism

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Top results for pulmonary embolism

41. Acute Pulmonary Embolism in a National Danish Cohort: Increasing Incidence and Decreasing Mortality

Acute Pulmonary Embolism in a National Danish Cohort: Increasing Incidence and Decreasing Mortality This study reports the incidence, clinical profile and mortality for acute pulmonary embolism (PE) patients in the Danish population in four eras from 2004 to 2014. Patients admitted with first-time acute PE from 2004 through 2014 were identified from national patient registries classified according to the International Classification of Diseases, 10th edition, World Health Organization. A total

2018 EvidenceUpdates

42. Sex-specific performance of pre-imaging diagnostic algorithms for pulmonary embolism

Sex-specific performance of pre-imaging diagnostic algorithms for pulmonary embolism Essentials Decision rules for pulmonary embolism are used indiscriminately despite possible sex-differences. Various pre-imaging diagnostic algorithms have been investigated in several prospective studies. When analysed at an individual patient data level the algorithms perform similarly in both sexes. Estrogen use and male sex were associated with a higher prevalence in suspected pulmonary embolism.Background (...) In patients suspected of pulmonary embolism (PE), clinical decision rules are combined with D-dimer testing to rule out PE, avoiding the need for imaging in those at low risk. Despite sex differences in several aspects of the disease, including its diagnosis, these algorithms are used indiscriminately in women and men. Objectives To compare the performance, defined as efficiency and failure rate, of three pre-imaging diagnostic algorithms for PE between women and men: the Wells rule with fixed or with age

2018 EvidenceUpdates

43. Rapid blood test helps exclude pulmonary embolism for low risk patients

Rapid blood test helps exclude pulmonary embolism for low risk patients Rapid blood test helps exclude pulmonary embolism for low risk patients Discover Portal Discover Portal Rapid blood test helps exclude pulmonary embolism for low risk patients Published on 25 October 2016 doi: An inexpensive blood test can help quickly rule out pulmonary embolism for low risk patients attending hospital outpatient or emergency departments, especially in people with early symptoms. This review looked (...) diagnostic imaging. Overall a change in the management pathway for suspected pulmonary embolism (PE) have potential to be cost saving and provide better care. Commissioners, will be interested in the overall pathway costs but unfortunately these were not researched here. Share your views on the research. Why was this study needed? In the UK, 47,734 cases of PE were reported between 2014 and 2015. Emergency admissions for PE increased by 30% between 2008 and 2012. A pulmonary embolism is a blockage

2018 NIHR Dissemination Centre

44. Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism

Venous thromboembolism in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism V Venous thromboembolism in o enous thromboembolism in ov ver 16s: er 16s: reducing the risk of hospital-acquired reducing the risk of hospital-acquired deep v deep vein thrombosis or pulmonary ein thrombosis or pulmonary embolism embolism NICE guideline Published: 21 March 2018 nice.org.uk/guidance/ng89 © NICE 2019. All rights reserved. Subject to Notice of rights (https (...) in over 16s: reducing the risk of hospital-acquired deep vein thrombosis or pulmonary embolism (NG89) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 41Contents Contents Overview 5 Who is it for? 5 Recommendations 6 1.1 Risk assessment 6 1.2 Giving information and planning for discharge 8 1.3 All patients 10 1.4 Interventions for people with acute coronary syndromes or acute stroke or for acutely ill patients 12

2018 National Institute for Health and Clinical Excellence - Clinical Guidelines

45. Combination of Pulmonary Embolism Rule-out Criteria and YEARS Algorithm in a European Cohort of Patients with Suspected Pulmonary Embolism

Combination of Pulmonary Embolism Rule-out Criteria and YEARS Algorithm in a European Cohort of Patients with Suspected Pulmonary Embolism Both the YEARS algorithm and the pulmonary embolism (PE) rule-out criteria (PERC) were created to exclude PE with limited diagnostic tests. A diagnostic strategy combining both scores might save additional computed tomography pulmonary angiography (CTPA) scans, but they have never been evaluated in conjunction.The aim of this study was to determine

2018 EvidenceUpdates

46. Blood and Clots Series: My patient has a pulmonary embolism. Should I screen them for cancer?

Blood and Clots Series: My patient has a pulmonary embolism. Should I screen them for cancer? Blood and Clots Series: My patient has a pulmonary embolism. Should I screen them for cancer? - CanadiEM Blood and Clots Series: My patient has a pulmonary embolism. Should I screen them for cancer? In , by Eric Tseng March 20, 2018 All the content from the Blood & Clots series can be found . CanMEDS Roles addressed: Expert, Leader Case Description An 83 year old female presents for follow-up after

2018 CandiEM

47. Effect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients: The PROPER Randomized Clinical Trial. (PubMed)

Effect of the Pulmonary Embolism Rule-Out Criteria on Subsequent Thromboembolic Events Among Low-Risk Emergency Department Patients: The PROPER Randomized Clinical Trial. The safety of the pulmonary embolism rule-out criteria (PERC), an 8-item block of clinical criteria aimed at ruling out pulmonary embolism (PE), has not been assessed in a randomized clinical trial.To prospectively validate the safety of a PERC-based strategy to rule out PE.A crossover cluster-randomized clinical (...) that was not initially diagnosed. The noninferiority margin was set at 1.5%. Secondary end points included the rate of computed tomographic pulmonary angiography (CTPA), median length of stay in the emergency department, and rate of hospital admission.Among 1916 patients who were cluster-randomized (mean age 44 years, 980 [51%] women), 962 were assigned to the PERC group and 954 were assigned to the control group. A total of 1749 patients completed the trial. A PE was diagnosed at initial presentation in 26 patients

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2018 JAMA Controlled trial quality: predicted high

48. Clinical prediction rules for mortality in patients with pulmonary embolism and cancer to guide outpatient management: a meta-analysis

Clinical prediction rules for mortality in patients with pulmonary embolism and cancer to guide outpatient management: a meta-analysis Essentials Clinical prediction rules (CPRs) can stratify patients with pulmonary embolism (PE) and cancer. A meta-analysis was done to assess prognostic accuracy in CPRs for mortality in these patients. Eight studies evaluating ten CPRs were included in this study. CPRs should continue to be used with other patient factors for mortality risk (...) stratification.Background Cancer treatment is commonly complicated by pulmonary embolism (PE), which remains a leading cause of morbidity and mortality in these patients. Some guidelines recommend the use of clinical prediction rules (CPRs) to help clinicians identify patients at low risk of mortality and therefore guide care. Objective To determine and compare the accuracy of available CPRs for identifying cancer patients with PE at low risk of mortality. Methods A literature search of Medline and Scopus (January 2000

2018 EvidenceUpdates

49. Treating pulmonary embolism at home?

Treating pulmonary embolism at home? Treating pulmonary embolism at home? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Treating pulmonary embolism at home? View/ Open Date 2012-06 Format Metadata Abstract Treat low-risk patients with pulmonary embolism (PE) with low-molecular-weight heparin (LMWH) in an outpatient

2018 PURLS

50. Pulmonary embolism

Pulmonary embolism Pulmonary embolism - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Pulmonary embolism Last reviewed: February 2019 Last updated: July 2018 Summary Pulmonary embolism (PE) is a life-threatening condition resulting from dislodged thrombi occluding the pulmonary vasculature; right heart failure and cardiac arrest may ensue if not aggressively treated. Symptoms include chest pain, dyspnoea, and a sense (...) , and supportive care. For those at intermediate risk of a poor outcome, anticoagulation and ongoing monitoring is required and rescue re-perfusion should be considered. Ongoing anticoagulation therapy is indicated to reduce the risk of recurrent events or fatal PE. Definition Pulmonary embolism (PE) is a consequence of thrombus formation within a deep vein of the body, most frequently in the lower extremities. Thrombus formation in the venous system occurs as a result of venous stasis, trauma

2018 BMJ Best Practice

51. Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism

Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism | CADTH.ca Find the information you need Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism Optimal Strategies for the Diagnosis of Acute Pulmonary Embolism Published on: March 1, 2018 Project Number: OP0528-000 Product Line: Research Type: Other Diagnostics Result type: Report Pulmonary embolism (PE) is a blockage of one of the arteries in the lung (...) as potential environmental impact were also addressed. Tags blood, decision support techniques, diagnostic tests, echocardiography, fibrin fibrinogen degradation products, magnetic resonance imaging, pet scan, perfusion imaging, positron-emission tomography, pulmonary embolism, radionuclide imaging, spect, tomography, ultrasonography, venous thromboembolism, ct scan, imaging, mri, respiratory, ultrasound, CT angiography, CT pulmonary angiography, CTPA, Emission-Computed, Geneva, MRIs, PERC, PET, PET-CT

2018 CADTH - Optimal Use

52. Clinical Value of Ultrasonography in Diagnosis of Pulmonary Embolism in Critically Ill Patients (PubMed)

Clinical Value of Ultrasonography in Diagnosis of Pulmonary Embolism in Critically Ill Patients Pulmonary embolism (PE) is a clinical emergency that will increase the mortality if complicated with unstable hemodynamics. Because of its nonspecific clinical symptoms, it's a great challenge to make a PE diagnosis. The golden standard to diagnose PE is computed tomography of pulmonary artery (CTPA), but a diagnosis of PE also composed of evaluation of PE risk factors, possibilities, and risk (...) stratification. Ultrasonography may detect right ventricle strain related to hemodynamic change, intravascular thrombosis, thrombosis in right heart or pulmonary arteries, pulmonary infarction, and local pleural effusion. Combination of ultrasound and traditional PE possibility evaluation score may further improve the pretest probability of CTPA. A comprehensive ultrasonography may sometimes rule out PE and may disclose other causes for the clinical situations. A heart-lung-vessel-integrated multiorgan

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2017 Journal of translational internal medicine

53. No added value of the age-adjusted D-dimer cut-off to the YEARS algorithm in patients with suspected pulmonary embolism

No added value of the age-adjusted D-dimer cut-off to the YEARS algorithm in patients with suspected pulmonary embolism Essentials Imaging is warranted in the majority of patients to confirm or rule out pulmonary embolism (PE). The age-adjusted D-dimer (ADJUST) reduced the number of required imaging tests in patients ≥ 50 years. The YEARS algorithm was designed to improve the efficiency in patients with suspected PE. There was no added value of implementing ADJUST in the YEARS algorithm in our (...) cohort.Background The YEARS algorithm was designed to simplify the diagnostic work-up of pulmonary embolism (PE) and to reduce the number of necessary computed tomography pulmonary angiography (CTPA) scans. An alternative strategy to reduce the number of CTPAs is the age-adjusted D-dimer cut-off (ADJUST) in patients aged 50 years or older. We aimed to investigate whether a combination of both diagnostic strategies might save additional CTPAs. Methods The YEARS algorithm consists of three items (clinical signs

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2017 EvidenceUpdates

54. Blood and Clots Quizlet 1: Oral Contraceptives and Pulmonary Embolism

Blood and Clots Quizlet 1: Oral Contraceptives and Pulmonary Embolism Blood and Clots Quizlet 1: Oral Contraceptives and Pulmonary Embolism - CanadiEM Blood and Clots Quizlet 1: Oral Contraceptives and Pulmonary Embolism In , by Eric Tseng October 27, 2017 Hello Blood & Clots/CanadiEM community! Before we post our blog series on thrombosis and bleeding, we encourage you to test your initial knowledge by going through a few brief case scenarios. These cases were originally posted as part of our (...) to someone who started COC only 3 months prior. In this situation her pre-test probability is driven not by her COC but her clinical presentation. Therefore, it is reasonable to perform a D-Dimer test to exclude pulmonary embolism as she is low pretest probability. This conservative approach may obviate the need for CT scan and avoid radiation exposure. Question 3: You discover that she has a family history of a hypercoagulable disorder. How does this change management? A) This is highly unlikely

2017 CandiEM

55. Approaches to Diagnosing Acute Pulmonary Embolism in Canada: current practice, challenges, and availability of testing

Approaches to Diagnosing Acute Pulmonary Embolism in Canada: current practice, challenges, and availability of testing Approaches to Diagnosing Acute Pulmonary Embolism in Canada: current practice, challenges, and availability of testing | CADTH.ca Find the information you need Approaches to Diagnosing Acute Pulmonary Embolism in Canada: current practice, challenges, and availability of testing Approaches to Diagnosing Acute Pulmonary Embolism in Canada: current practice, challenges (...) , and availability of testing Published on: September 8, 2017 Project Number: ES0307-000 Product Line: Result type: Report CADTH undertook an environmental scan to identify and summarize information regarding pulmonary embolism (PE) imaging in Canada. The scan described current practice, challenges, and enablers in diagnosing PE, and the availability of tests, scans, and tools for diagnosing PE. The key objectives of this environmental scan were as follows: Identify current practice related to diagnostic

2017 Canadian Agency for Drugs and Technologies in Health - Environmental Scanning

56. Assessing clinical probability of pulmonary embolism: prospective validation of the simplified Geneva score

Assessing clinical probability of pulmonary embolism: prospective validation of the simplified Geneva score Essentials The simplified Geneva score allows easier pretest probability assessment of pulmonary embolism (PE). We prospectively validated this score in the ADJUST-PE management outcome study. The study shows that it is safe to manage patients with suspected PE according to this score. The simplified Geneva score is now ready for use in routine clinical practice.Background Pretest (...) probability assessment by a clinical prediction rule (CPR) is an important step in the management of patients with suspected pulmonary embolism (PE). A limitation to the use of CPRs is that their constitutive variables and corresponding number of points are difficult to memorize. A simplified version of the Geneva score (i.e. attributing one point to each variable) has been proposed but never been prospectively validated. Aims Prospective validation of the simplified Geneva score (SGS) and comparison

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2017 EvidenceUpdates

57. Pulmonary embolism prognostic factors and length of hospital stay: A cohort study

Pulmonary embolism prognostic factors and length of hospital stay: A cohort study Patients with pulmonary embolism (PE) are commonly admitted to hospital for their initial treatment. We aimed to assess the association of length of hospital stay with commonly available clinical variables and their combinations.A retrospective multicenter cohort study was conducted on consecutive PE patients admitted to eight Italian centers. Logistic regression analysis was performed to evaluate the association (...) between the length of hospital stay and the Pulmonary Embolism Severity Index (PESI) parameters, National Early Warning Score (NEWS) and other possible determinants.We enrolled 391 patients, with a median hospital stay of 10days (IQR 7-14). Among PESI parameters, only oxygen saturation <90% was significantly associated with length of hospital stay at univariable analysis (OR 1.99; 95% CI 1.3-3.2). At multivariable analysis, NEWS ≥5 was associated with prolonged hospitalization (OR 3.14; 95% CI 1.2-8.3

2017 EvidenceUpdates

58. Lixiana (edoxaban) - for the prevention of embolism in patients with nonvalvular atrial fibrillation OR treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) and prevention of recurrent DVT and PE.

Lixiana (edoxaban) - for the prevention of embolism in patients with nonvalvular atrial fibrillation OR treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) and prevention of recurrent DVT and PE. Lixiana (edoxaban) × Insert searchphrase to search the website Insert searchphrase to search the website > > > Lixiana (edoxaban) Conclusion Lixiana (edoxaban) is the fourth Non-vitamin K Oral Anticoagulant (NOAC) in Denmark after Eliques (apixaban), Xarelto (rivaroxaban) and Pradaxa (...) (dabigatran). Lixiana is indicated for the prevention of embolism in patients with nonvalvular atrial fibrillation (NVAF) with one or more risk factors and treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE) and prevention of recurrent DVT and PE. For either indication, Lixiana is not inferior to warfarin when it comes to preventing embolism and has a statistically significantly lower occurrence of major bleeding. The lower risk of bleeding is particularly evident in comparisons

2017 Danish Pharmacotherapy Reviews

59. Derivation and Validation of a Novel Prediction Model to Identify Low-Risk Patients With Acute Pulmonary Embolism

Derivation and Validation of a Novel Prediction Model to Identify Low-Risk Patients With Acute Pulmonary Embolism Accurate identification of low-risk patients with acute pulmonary embolism (PE) who may be eligible for outpatient treatment or early discharge can have substantial cost-saving benefit. The purpose of this study was to derive and validate a prediction model to effectively identify patients with PE at low risk of short-term mortality, right ventricular dysfunction, and other nonfatal

2017 EvidenceUpdates

60. Impact of residual pulmonary obstruction on the long-term outcome of patients with pulmonary embolism

Impact of residual pulmonary obstruction on the long-term outcome of patients with pulmonary embolism The impact of residual pulmonary obstruction on the outcome of patients with pulmonary embolism is uncertain.We recruited 647 consecutive symptomatic patients with a first episode of pulmonary embolism, with or without concomitant deep venous thrombosis. They received conventional anticoagulation, were assessed for residual pulmonary obstruction through perfusion lung scanning after 6 months (...) of the 324 patients (10.5%) with residual pulmonary obstruction and in 15 out of the 323 patients (4.6%) without residual pulmonary obstruction, leading to an adjusted hazard ratio of 2.26 (95% CI 1.23-4.16).Residual pulmonary obstruction, as detected with perfusion lung scanning at 6 months after a first episode of pulmonary embolism, is an independent predictor of recurrent venous thromboembolism and/or chronic thromboembolic pulmonary hypertension.Copyright ©ERS 2017.

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2017 EvidenceUpdates