Latest & greatest articles for pulmonary embolism

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Top results for pulmonary embolism

1. Increasing Safe Outpatient Management of Emergency Department Patients With Pulmonary Embolism: A Controlled Pragmatic Trial.

Increasing Safe Outpatient Management of Emergency Department Patients With Pulmonary Embolism: A Controlled Pragmatic Trial. Background: Many low-risk patients with acute pulmonary embolism (PE) in the emergency department (ED) are eligible for outpatient care but are hospitalized nonetheless. One impediment to home discharge is the difficulty of identifying which patients can safely forgo hospitalization. Objective: To evaluate the effect of an integrated electronic clinical decision support (...) system (CDSS) to facilitate risk stratification and decision making at the site of care for patients with acute PE. Design: Controlled pragmatic trial. (ClinicalTrials.gov: NCT03601676 ). Setting: All 21 community EDs of an integrated health care delivery system (Kaiser Permanente Northern California). Patients: Adult ED patients with acute PE. Intervention: Ten intervention sites selected by convenience received a multidimensional technology and education intervention at month 9 of a 16-month study

Annals of Internal Medicine2018

3. Accuracy and Interobserver Reliability of the Simplified Pulmonary Embolism Severity Index Versus the Hestia Criteria for Patients With Pulmonary Embolism

Accuracy and Interobserver Reliability of the Simplified Pulmonary Embolism Severity Index Versus the Hestia Criteria for Patients With Pulmonary Embolism 30155937 2018 10 10 1553-2712 2018 Aug 29 Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med Accuracy and Interobserver Reliability of the Simplified Pulmonary Embolism Severity Index Versus the Hestia Criteria for Patients With Pulmonary Embolism. 10.1111/acem.13561 The objective (...) was to assess and compare the accuracy and interobserver reliability of the simplified Pulmonary Embolism Severity Index (sPESI) and the Hestia criteria for predicting short-term mortality in patients with pulmonary embolism (PE). This prospective cohort study evaluated consecutive eligible adults with PE diagnosed in the emergency department (ED) at a large, tertiary, academic medical center in the era January 1, 2015, to December 30, 2017. We assessed and compared sPESI and Hestia criteria prognostic

EvidenceUpdates2018

4. Rapid blood test helps exclude pulmonary embolism for low risk patients

Rapid blood test helps exclude pulmonary embolism for low risk patients Signal - Rapid blood test helps exclude pulmonary embolism for low risk patients Dissemination Centre Discover Portal NIHR DC Discover Rapid blood test helps exclude pulmonary embolism for low risk patients Published on 25 October 2016 An inexpensive blood test can help quickly rule out pulmonary embolism for low risk patients attending hospital outpatient or emergency departments, especially in people with early symptoms (...) positive will still need diagnostic imaging. Overall a change in the management pathway for suspected pulmonary embolism (PE) have potential to be cost saving and provide better care. Commissioners, will be interested in the overall pathway costs but unfortunately these were not researched here. Share your views on the research. Why was this study needed? In the UK, 47,734 cases of PE were reported between 2014 and 2015. Emergency admissions for PE increased by 30% between 2008 and 2012. A pulmonary embolism

NIHR Dissemination Centre2018

6. Safety of the Combination of PERC and YEARS Rules in Patients With Low Clinical Probability of Pulmonary Embolism: A Retrospective Analysis of Two Large European Cohorts

Safety of the Combination of PERC and YEARS Rules in Patients With Low Clinical Probability of Pulmonary Embolism: A Retrospective Analysis of Two Large European Cohorts 29947451 2018 08 10 1553-2712 2018 Jun 27 Academic emergency medicine : official journal of the Society for Academic Emergency Medicine Acad Emerg Med Safety of the Combination of PERC and YEARS Rules in Patients With Low Clinical Probability of Pulmonary Embolism: A Retrospective Analysis of Two Large European Cohorts. 10.1111 (...) /acem.13508 This study aimed to determine the failure rate of a combination of the PERC and the YEARS rules for the diagnosis of pulmonary embolism (PE) in the emergency department (ED). We performed a retrospective analysis of two European cohorts of emergency patients with low gestalt clinical probability of PE (PROPER and PERCEPIC). All patients we included were managed using a conventional strategy (D-dimer test, followed, if positive, by computed tomographic pulmonary angiogram (CTPA). We

EvidenceUpdates2018

7. Prevalence of pulmonary embolism in syncope

Prevalence of pulmonary embolism in syncope Emergency Medicine > Journal Club > Archive > March 2018 Toggle navigation March 2018 2018 Prevalence of PE in Syncope Vignette You're working a TCC shift with Dr. Cohn, sitting right beside you. He's drinking a Diet Coke, having not offered you one. You decide to go see your next patient, a 78 year old female, complaining of "feeling woozy". she endorses syncope, shortness of breath, and leg pain. She is saturating 89% on room air, tachycardic to 104 (...) , and BP 117/76. She has many other reasons other than a pulmonary embolism to be feeling this way, but the syncope has you thinking. You remember reading an article that was all the rage a few months ago regarding syncope as a presenting complaint for PE. It was fake news, you said. So vague. But here you are. You've got a minute, and Dr. Cohn by your side. You search the literature and gently fall into a rabbit hole... PICO Question Population: Adult patients presenting to the ED with syncope and

Washington University Emergency Medicine Journal Club2018

8. Selecting pregnant or postpartum women with suspected pulmonary embolism for diagnostic imaging: the DiPEP diagnostic study with decision-analysis modelling

Selecting pregnant or postpartum women with suspected pulmonary embolism for diagnostic imaging: the DiPEP diagnostic study with decision-analysis modelling Selecting pregnant or postpartum women with suspected pulmonary embolism for diagnostic imaging: the DiPEP diagnostic study with decision-analysis modelling Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found (...) . Please choose a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> {{metadata.Title}} {{metadata.Headline}} Clinical features, decision rules and biomarkers do not accurately select pregnant or postpartum women with suspected pulmonary embolism for diagnostic imaging. {{author}} {{($index , , , , , , , , , & . Steve Goodacre 1, * , Kimberley Horspool 1 , Neil Shephard 1 , Daniel Pollard 1 , Beverley J Hunt

NIHR HTA programme2018

10. Evaluation of the pulmonary embolism rule out criteria (PERC rule) in children evaluated for suspected pulmonary embolism

Evaluation of the pulmonary embolism rule out criteria (PERC rule) in children evaluated for suspected pulmonary embolism 29864629 2018 07 31 1879-2472 168 2018 Aug Thrombosis research Thromb. Res. Evaluation of the pulmonary embolism rule out criteria (PERC rule) in children evaluated for suspected pulmonary embolism. 1-4 S0049-3848(18)30367-0 10.1016/j.thromres.2018.05.026 The pulmonary embolism rule out criteria (PERC) reliably predicts a low probability of PE in adults. We examine (...) the diagnostic accuracy of the objective components of the PERC rule in children previously tested for PE. Children aged 5-17 who had a D-dimer or pulmonary vascular imaging ordered from 2004 to 2014 in a large multicenter hospital network were identified by query of administrative databases. Using explicit, predefined methods, trained abstracters selected charts of children clearly tested for PE, collected the 8 objective variables for PERC, and determined PE criterion standard status (image or autopsy

EvidenceUpdates2018

11. Prediction of short-term prognosis in elderly patients with acute pulmonary embolism: validation of the RIETE score

Prediction of short-term prognosis in elderly patients with acute pulmonary embolism: validation of the RIETE score 29733493 2018 07 04 1538-7836 16 7 2018 Jul Journal of thrombosis and haemostasis : JTH J. Thromb. Haemost. Prediction of short-term prognosis in elderly patients with acute pulmonary embolism: validation of the RIETE score. 1313-1320 10.1111/jth.14137 Essentials The RIETE score was derived to predict 10-day adverse outcomes in acute pulmonary embolism (PE). We externally (...) validated the RIETE score in a prospective cohort of patients with PE. The RIETE score classified fewer patients as low-risk than currently recommended scores. The RIETE score was not superior to other scores in predicting 10-day adverse outcomes. Introduction The Registro Informatizado de la Enfermedad TromboEmbolica (RIETE) score was derived to identify patients with pulmonary embolism (PE) at low risk of overall complications. Objective To externally validate the RIETE score and compare its

EvidenceUpdates2018

12. Pulmonary embolism

Pulmonary embolism Top results for pulmonary embolism - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box (...) and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for pulmonary embolism The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical

Trip Latest and Greatest2018

13. Outcomes following a negative computed tomography pulmonary angiography according to pulmonary embolism prevalence: a meta-analysis of the management outcome studies

Outcomes following a negative computed tomography pulmonary angiography according to pulmonary embolism prevalence: a meta-analysis of the management outcome studies 29645405 2018 06 01 1538-7836 16 6 2018 Jun Journal of thrombosis and haemostasis : JTH J. Thromb. Haemost. Outcomes following a negative computed tomography pulmonary angiography according to pulmonary embolism prevalence: a meta-analysis of the management outcome studies. 1107-1120 10.1111/jth.14021 Essentials Computed (...) tomographic pulmonary angiography (CTPA) is used to exclude pulmonary embolism. This meta-analysis explores the occurrence of venous thromboembolic events (VTE) after a CTPA. Occurrence of VTE after a negative CTPA is ˜8% in study subgroups with a prevalence of PE40%. CTPA may be insufficient to safely rule out VTE as a stand-alone diagnostic test for this subgroup. Background Outcome studies have reported the safety of computed tomographic pulmonary angiography (CTPA) as a stand-alone imaging

EvidenceUpdates2018

14. Prognostic impact of copeptin in pulmonary embolism: a multicentre validation study

Prognostic impact of copeptin in pulmonary embolism: a multicentre validation study 29599188 2018 04 20 1399-3003 51 4 2018 Apr The European respiratory journal Eur. Respir. J. Prognostic impact of copeptin in pulmonary embolism: a multicentre validation study. 1702037 10.1183/13993003.02037-2017 To externally validate the prognostic impact of copeptin, either alone or integrated in risk stratification models, in pulmonary embolism (PE), we performed a post hoc analysis of 843 normotensive PE (...) patients prospectively included in three European cohorts.Within the first 30 days, 21 patients (2.5%, 95% CI 1.5-3.8) had an adverse outcome and 12 (1.4%, 95% CI 0.7-2.5) died due to PE. Patients with copeptin ≥24 pmol·L -1 had a 6.3-fold increased risk for an adverse outcome (95% CI 2.6-15.5, p<0.001) and a 7.6-fold increased risk for PE-related death (95% CI 2.3-25.6, p=0.001). Risk classification according to the 2014 European Society of Cardiology (ESC) guideline algorithm identified 248

EvidenceUpdates2018

15. Pulmonary embolism

Pulmonary embolism Autosynthesis - Trip Database or use your Google+ account Turning Research Into Practice My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing

Trip Evidence Maps2018

16. A prospective validation of the Bova score in normotensive patients with acute pulmonary embolism

A prospective validation of the Bova score in normotensive patients with acute pulmonary embolism 29631073 2018 05 14 1879-2472 165 2018 05 Thrombosis research Thromb. Res. A prospective validation of the Bova score in normotensive patients with acute pulmonary embolism. 107-111 S0049-3848(18)30300-1 10.1016/j.thromres.2018.04.002 The Bova score has shown usefulness in the identification of intermediate-high risk patients with acute pulmonary embolism (PE), but lacks prospective validation (...) . The aim of this study was to prospectively validate the Bova score in different settings from the original derivation cohort. Consecutive, normotensive patients with acute PE recruited at 13 academic or general hospitals were stratified, using their baseline data, into the three Bova risk stages (I-III). The primary outcome was the 30-day composite of PE-related mortality, hemodynamic collapse and non-fatal PE recurrences in the three risk categories. In the study period, 639 patients were enrolled

EvidenceUpdates2018

18. Assessment of coexisting deep vein thrombosis for risk stratification of acute pulmonary embolism

Assessment of coexisting deep vein thrombosis for risk stratification of acute pulmonary embolism 29476988 2018 04 24 1879-2472 164 2018 04 Thrombosis research Thromb. Res. Assessment of coexisting deep vein thrombosis for risk stratification of acute pulmonary embolism. 40-44 S0049-3848(18)30212-3 10.1016/j.thromres.2018.02.140 In patients with acute pulmonary embolism (PE), studies have shown an association between coexisting deep vein thrombosis (DVT) and short-term prognosis (...) . It is not known whether complete compression ultrasound testing (CCUS) improves the risk stratification of their disease beyond the recommended prognostic models. We included patients with normotensive acute symptomatic PE and prognosticated them with the European Society of Cardiology (ESC) risk model for PE. Subsequently, we determined the prognostic significance of coexisting DVT in patients with various ESC risk categories. The primary endpoint was a complicated course after the diagnosis of PE, defined

EvidenceUpdates2018

19. Acute Pulmonary Embolism in a National Danish Cohort: Increasing Incidence and Decreasing Mortality

Acute Pulmonary Embolism in a National Danish Cohort: Increasing Incidence and Decreasing Mortality 29536465 2018 03 14 2567-689X 118 3 2018 Mar Thrombosis and haemostasis Thromb. Haemost. Acute Pulmonary Embolism in a National Danish Cohort: Increasing Incidence and Decreasing Mortality. 539-546 10.1160/TH17-08-0531 This study reports the incidence, clinical profile and mortality for acute pulmonary embolism (PE) patients in the Danish population in four eras from 2004 to 2014. Patients (...) admitted with first-time acute PE from 2004 through 2014 were identified from national patient registries classified according to the International Classification of Diseases, 10th edition, World Health Organization. A total of 30,275 patients from a population of 4,301,673 adult residents aged 18 years or older were diagnosed with first-time acute PE, corresponding to an incidence of 64 (95% confidence interval: 61-66) per 100,000 adult residents per year. Throughout the study period, PE incidence

EvidenceUpdates2018

20. Sex-specific performance of pre-imaging diagnostic algorithms for pulmonary embolism

Sex-specific performance of pre-imaging diagnostic algorithms for pulmonary embolism 29460484 2018 05 02 1538-7836 16 5 2018 May Journal of thrombosis and haemostasis : JTH J. Thromb. Haemost. Sex-specific performance of pre-imaging diagnostic algorithms for pulmonary embolism. 858-865 10.1111/jth.13984 Essentials Decision rules for pulmonary embolism are used indiscriminately despite possible sex-differences. Various pre-imaging diagnostic algorithms have been investigated in several (...) prospective studies. When analysed at an individual patient data level the algorithms perform similarly in both sexes. Estrogen use and male sex were associated with a higher prevalence in suspected pulmonary embolism. Background In patients suspected of pulmonary embolism (PE), clinical decision rules are combined with D-dimer testing to rule out PE, avoiding the need for imaging in those at low risk. Despite sex differences in several aspects of the disease, including its diagnosis, these algorithms

EvidenceUpdates2018