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Predictors of post-traumaticstressdisorder following critical illness: A mixed methods study Post-traumaticstressdisorder has been reported in survivors of critical illness. The aim of this study was to investigate the predictors of post-traumaticstressdisorder in survivors of critical illness.Patients attending the intensive care unit (ICU) follow-up clinic completed the UK-Post-TraumaticStress Syndrome 14-Questions Inventory and data was collected from their medical records. Predictors (...) investigated included age, gender, Apache II score, ICU length of stay, pre-illness psychopathology; delirium and benzodiazepine administration during ICU stay and delusional memories of the ICU stay following discharge.A total of 198 patients participated, with 54 (27%) patients suffering with post-traumaticstressdisorder. On multivariable logistic regression, the significant predictors of post-traumaticstressdisorder were younger age, lower Apache II score, pre-illness psychopathology and delirium
-traumaticstressdisorder (PTSD) is the third most common psychiatric diagnosis among Veterans treated within the VA healthcare system. Experts estimate that up to 20% of Operation Enduring Freedom and Operation Iraqi Freedom (OEF/OIF) Veterans, up to 12% of Gulf War Veterans, and up to 30% of Vietnam War Veterans have experienced PTSD. Consequently, the need for PTSD treatment may increase within the Veteran population in the coming years. Conventional treatments for PTSD include psychotherapy (...) Effectiveness of Stellate Ganglion Block for Treatment of PTSD Management Briefs eBrief-no124 -- Enter search terms Button to search HSRD ® Inside VA Budget and Performance Inside the News Room National Observances Special Events » » » » » Management Briefs eBrief-no124 -- Health Services Research & Development Management eBrief no. 124 » Issue 124 March 2017 The report is a product of the VA/HSR&D Evidence Synthesis Program. Effectiveness of Stellate Ganglion Block for Treatment of PTSDPost
Secondary traumaticstress, dissociative and somatization symptoms in spouses of veterans with PTSD in Zahedan, Iran Secondary traumaticstress is a disorder which occurs in spouses and people with close relation to someone with posttraumatic stressdisorder. Like PTSD, it seems that STS also occurs with other psychiatric problems like somatization and dissociation. This study aimed to determine the relationship between STS and somatization and dissociation symptoms.This cross-sectional study (...) was done in 2015 and lasted for one year. Self-report questionnaires assessing secondary traumaticstress symptoms, dissociation symptoms and somatization symptoms were distributed among spouses of veterans with PTSD in Zahedan, Iran. The relationship between STS symptoms and somatization symptoms and also between STS symptoms and dissociation symptoms were determined by Pearson correlation test. SPSS version 23 was used for data analysis.Occurrence of secondary traumaticstress symptoms were
The Genetics and Epigenetics of PTSD: Overview, Recent Advances, and Future Directions This paper provides a brief summary and commentary on the growing literature and current developments related to the genetic underpinnings of posttraumatic stressdisorder (PTSD). We first briefly provide an overview of the behavioral genetic literature on PTSD, followed by a short synopsis of the substantial candidate gene literature with a focus on genes that have been meta-analyzed. We then discuss (...) the genome-wide association studies (GWAS) that have been conducted, followed by an introduction to other molecular platforms used in PTSD genomic studies, such as epigenetic and expression approaches. We close with a discussion of developments in the field that include the creation of the PTSD workgroup of the Psychiatric Genomics Consortium, statistical advances that can be applied to GWAS data to answer questions of heritability and genetic overlap across phenotypes, and bioinformatics techniques
diagnosis was disc displacement with reduction (8%). Each group had one patient that was fully edentulous. There was no statistical significant difference between the two groups for the DMFT index (P=0.36); nevertheless, the group with the PTSD patients had more missing teeth, more decay present, and less filled teeth than the control group (P Evidence Search ("StressDisorders, Post-Traumatic"[Mesh]) AND "Temporomandibular Joint Disorders"[Mesh] Comments on The Evidence Validity: A strength (...) PTSD Is a Risk Factor for the Development of TMD and a Decline in Oral Health Conditions UTCAT3189, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title PTSD Is a Risk Factor for the Development of TMD and a Decline in Oral Health Conditions Clinical Question In adults, would having PTSD increase the likelihood of developing a temporomandibular disorder and experiencing a decline in oral health conditions, compared to those
of stellate ganglion block (SGB) for treatment of posttraumatic stressdisorder (PTSD). Findings from this evidence brief will be used to inform Subject Matter Experts’ consideration of clinical use and research and program prioritization for SGB for PTSD in VA. BACKGROUND Posttraumatic StressDisorder (PTSD) and Its Impact Posttraumatic stressdisorder (PTSD) is a trauma- and stress-related disorder than can develop following exposure to a traumatic event. PTSD can affect survivors not only of combat (...) ) Veterans, from 1st Qtr FY 2002 through 2nd Qtr FY 2015. In: Affairs V, ed. Washington, DC2015. 4. Hoge CW, Castro CA, Messer SC, McGurk D, Cotting DI, Koffman RL. Combat duty in Iraq and Afghanistan, mental health problems and barriers to care. U.S. Army Medical Department journal. Jul-Sep 2008:7-17. 5. Terhakopian A, Sinaii N, Engel CC, Schnurr PP, Hoge CW. Estimating population prevalence of posttraumatic stressdisorder: an example using the PTSD checklist. Journal of traumaticstress. Jun 2008;21(3
guidelines for the use of human growth hormone for patients with depression, post-traumaticstressdisorder, or fibromyalgia? Key Message Two randomized controlled trials were identified regarding the clinical effectiveness of human growth hormone for patients with fibromyalgia. One non-randomized study was identified regarding the clinical effectiveness of human growth hormone for patients with depression. Tags mental health, combatdisorders, depression, depressive disorder, depressive disorder, major (...) Human Growth Hormone for Depression, Post-TraumaticStressDisorder, or Fibromyalgia: Clinical Effectiveness and Guidelines Human Growth Hormone for Depression, Post-TraumaticStressDisorder, or Fibromyalgia: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Human Growth Hormone for Depression, Post-TraumaticStressDisorder, or Fibromyalgia: Clinical Effectiveness and Guidelines Human Growth Hormone for Depression, Post-TraumaticStressDisorder, or Fibromyalgia
Review Recent studies suggest that from 45% to 80% of individuals who seek cannabis for medical purposes do so for pain management, and an estimated 6% to 39% of patients who are prescribed opioid medication for pain also use cannabis. In addition, more than one-third of patients seeking cannabis for medical purposes cite post-traumaticstressdisorder (PTSD) as the primary reason for the request. Approximately 15% of Veterans who are treated in VA outpatient PTSD clinics report recent (past six (...) . The authors identified 10 ongoing clinical trials examining the effectiveness of cannabis for a variety of chronic pain populations including patients with neuropathic pain, cancer, osteoarthritis, sickle cell disease, low back pain, and ulcerative colitis. There are also two trials examining the benefits and harms of cannabis for PTSD that should add to the body of evidence. A cyberseminar session titled "Benefits and Harms of Cannabis in Chronic Pain or Post-TraumaticStressDisorder: A Systematic
Number: RC0838-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of medical marijuana for the treatment of post-traumaticstressdisorder (PTSD) in adults? What is the clinical effectiveness of synthetic cannabinoids for the treatment of PTSD in adults? What are the evidence-based guidelines regarding the use of medical marijuana or synthetic cannabinoids in adult patients with PTSD? Key Message Based (...) Medical Marijuana for Post-TraumaticStressDisorder: A Review of Clinical Effectiveness and Guidelines Medical Marijuana for Post-TraumaticStressDisorder: A Review of Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Medical Marijuana for Post-TraumaticStressDisorder: A Review of Clinical Effectiveness and Guidelines Medical Marijuana for Post-TraumaticStressDisorder: A Review of Clinical Effectiveness and Guidelines Published on: January 11, 2017 Project
Pharmacotherapy of post-traumaticstressdisorder: going beyond the guidelines This article discusses the study of Harpaz-Rotem and associates, who examined patterns of medication use in first-diagnosed veterans with post-traumaticstressdisorder (PTSD). It considers the difference between practice guidelines and actual prescribing; selectively identifies issues with antidepressants, antipsychotics, benzodiazepines and prazosin; and reviews the possible impact of new medications
Disturbed EEG sleep, paranoid cognition and somatic symptoms identify veterans with post-traumaticstressdisorder Chronic post-traumaticstressdisorder (PTSD) behavioural symptoms and medically unexplainable somatic symptoms are reported to occur following the stressful experience of military combatants in war zones.To determine the contribution of disordered EEG sleep physiology in those military combatants who have unexplainable physical symptoms and PTSD behavioural difficulties following (...) war-zone exposure.This case-controlled study compared 59 veterans with chronic sleep disturbance with 39 veterans with DSM-IV and clinician-administered PTSD Scale diagnosed PTSD who were unresponsive to pharmacological and psychological treatments. All had standardised EEG polysomnography, computerised sleep EEG cyclical alternating pattern (CAP) as a measure of sleep stability, self-ratings of combat exposure, paranoid cognition and hostility subscales of Symptom Checklist-90, Beck Depression
patients with or without comorbidities? Key Message Five systematic reviews and meta-analyses, 12 randomized controlled trials, and five non-randomized studies were identified regarding the use of narrative exposure therapy for the treatment of post-traumaticstressdisorder in adult patients with or without comorbidities. Tags mental health, anxiety disorders, depression, implosive therapy, narration, stressdisorders, post-traumatic, PTSD, Trauma, narrative explosive therapy, narrative explosive (...) Narrative Exposure Therapy for the Treatment of Post-TraumaticStressDisorder: Clinical Effectiveness and Guidelines Narrative Exposure Therapy for the Treatment of Post-TraumaticStressDisorder: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Narrative Exposure Therapy for the Treatment of Post-TraumaticStressDisorder: Clinical Effectiveness and Guidelines Narrative Exposure Therapy for the Treatment of Post-TraumaticStressDisorder: Clinical Effectiveness
significant differences in the comparative clinical effectiveness of inpatient versus outpatient treatment programs for patients with post-traumaticstressdisorder (PTSD). One study did not find a difference in the clinical effectiveness of long- versus short-term inpatient treatment programs. Another study found shorter treatment programs more effective shortly after discharge, but results tended to converge over time. No evidence was found on evidence-based guidelines regarding inpatient treatment (...) Long and Short Duration Inpatient Treatment Programs for the Treatment of Post-TraumaticStressDisorder: Comparative Effectiveness and Guidelines Long and Short Duration Inpatient Treatment Programs for the Treatment of Post-TraumaticStressDisorder: Comparative Effectiveness and Guidelines | CADTH.ca Find the information you need Long and Short Duration Inpatient Treatment Programs for the Treatment of Post-TraumaticStressDisorder: Comparative Effectiveness and Guidelines Long and Short
Perspectives on the Conceptualization of the Dissociative Subtype of PTSD and Implications for Treatment A dissociative subtype of PTSD was added to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) to denote a distinct presentation of PTSD marked by symptoms of derealization and depersonalization. The subtype has brought renewed interest in the conceptualization of dissociation in PTSD, and raised questions about its treatment. We review the evidence (...) for two models of PTSD-related dissociative symptoms and the treatment approaches that align with each. We find support for the contributions of biologically-based trait-level factors to dissociation, and suggest that empirically supported treatments for PTSD demonstrate efficacy for patients with the subtype.Published by Elsevier Ltd.
Patient characteristics as a moderator of post-traumaticstressdisorder treatment outcome: combining symptom burden and strengths. Post-traumaticstressdisorder (PTSD) psychotherapy research has failed to identify patient characteristics that consistently predict differential outcome.To identify patient characteristics associated with differential outcome via a statistically generated composite moderator among women with childhood abuse-related PTSD in a randomised controlled trial comparing (...) exposure therapy, skills training and their combination.Six baseline patient characteristics were combined in a composite moderator of treatment effects for PTSD symptoms across the three treatment conditions through a 6-month follow-up.The optimal moderator was the combined burden of all symptoms and emotion regulation strength. Those with high moderator scores, reflecting high symptom load relative to emotion regulation, did least well in exposure, moderately well in skills and best
Missed opportunity to screen and diagnose PTSD and depression among deploying shipboard US military personnel Depression and post-traumaticstressdisorder (PTSD) are significant risks for suicide and other adverse events among US military personnel, but prevalence data among ship-assigned personnel at the onset of deployment are unknown.To determine the prevalence of shipboard personnel who screen positive for PTSD and/or major depressive disorder (MDD) at the onset of deployment, and also (...) those who reported these diagnoses made by a physician or healthcare professional in the year prior to deployment.Active-duty ship-assigned personnel (N = 2078) completed anonymous assessments at the beginning of deployment. Depression was measured using the Center for Epidemiologic Studies Depression Scale (CES-D; score of ≥22), and PTSD was assessed using the PTSD Checklist-Civilian Version (PCL-C; both score and symptom criteria were used).In total, 7.3% (n = 151 of 2076) screened positive