Latest & greatest articles for proton pump inhibitors

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Top results for proton pump inhibitors

61. Adverse cardiovascular effects of concomitant use of proton pump inhibitors and clopidogrel in patients with coronary artery disease: a systematic review and meta-analysis

Adverse cardiovascular effects of concomitant use of proton pump inhibitors and clopidogrel in patients with coronary artery disease: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 DARE.

62. Are proton pump inhibitors associated with the development of community-acquired pneumonia? A meta-analysis

Are proton pump inhibitors associated with the development of community-acquired pneumonia? A meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 DARE.

63. Systematic review with meta-analysis: Proton pump inhibitor use may be associated with an increased risk of Clostridium difficile infection

Systematic review with meta-analysis: Proton pump inhibitor use may be associated with an increased risk of Clostridium difficile infection Proton pump inhibitor use may be associated with an increased risk of Clostridium difficile infection | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using (...) your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Proton pump inhibitor use may be associated with an increased risk of Clostridium difficile infection Article Text Aetiology Systematic review

2013 Evidence-Based Medicine

64. Cohort study: Proton pump inhibitors do not induce change in bone mineral density in a long-term observational study

Cohort study: Proton pump inhibitors do not induce change in bone mineral density in a long-term observational study Proton pump inhibitors do not induce change in bone mineral density in a long-term observational study | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Proton pump inhibitors do not induce change in bone mineral density in a long-term observational study Article Text Aetiology Cohort study Proton pump inhibitors do

2013 Evidence-Based Medicine

65. Cohort study: Lack of association between proton pump inhibitors and adverse events in patients taking clopidogrel and aspirin

of association between proton pump inhibitors and adverse events in patients taking clopidogrel and aspirin Ron Waksman 1 , Michael A Gaglia Jr 2 Statistics from Altmetric.com Commentary on Douglas IJ , Evans SJ , Hingorani AD , et al . Clopidogrel and interaction with proton pump inhibitors: comparison between cohort and within person study designs . Context Clopidogrel inhibits the P2Y12 platelet receptor and is used in patients with acute coronary syndromes or ischaemic stroke to prevent recurrent (...) vascular events. Proton pump inhibitors (PPIs), however, have been shown to reduce the pharmacodynamic effect of clopidogrel upon platelet inhibition, and have been linked in retrospective studies to a higher rate of ischaemic outcomes in patients taking clopidogrel. Methods A total of 24 471 patients in the General Practice Research Database in the UK (beginning in 2003) concurrently prescribed aspirin and clopidogrel were included. There were 12 439 (50%) patients receiving a PPI at some point during

2013 Evidence-Based Medicine

66. Are Proton-Pump Inhibitors Effective Treatment for Acute Undifferentiated Upper Gastrointestinal Bleeding?

Are Proton-Pump Inhibitors Effective Treatment for Acute Undifferentiated Upper Gastrointestinal Bleeding? Systematic Review Snapshot TAKE-HOME MESSAGE In patients with acute upper gastrointestinal bleeding, proton-pump inhibitor treatment before indexendoscopydoesnotimprovepatient-importantoutcomes. Are Proton-Pump Inhibitors Effective Treatment for Acute Undifferentiated Upper Gastrointestinal Bleeding? EBEM Commentators Jennifer C. Cabot, MD Kaushal Shah, MD Department of Emergency Medicine (...) Mount Sinai Hospital New York, NY Results Six trials with a total of 2,223 partici- pants were included. All studies were randomized controlled trials with a parallel-group design, conducted in a hospital setting. Four trials were con- ducted in Europe and 2 in Asia. There was no signi?cant heterogeneity among the trials (Table 2). Compared with the control group, proton-pump inhibitor treatment did not affect the rates of 30-day mortality, rebleeding, surgery, or blood transfusion (Table 1

2013 Annals of Emergency Medicine Systematic Review Snapshots

67. Cohort study: The association between proton pump inhibitor use and hip fracture cannot be explained by differences in dietary and lifestyle choices

Cohort study: The association between proton pump inhibitor use and hip fracture cannot be explained by differences in dietary and lifestyle choices The association between proton pump inhibitor use and hip fracture cannot be explained by differences in dietary and lifestyle choices | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use (...) cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here The association between proton pump inhibitor use and hip fracture cannot be explained by differences

2013 Evidence-Based Medicine

68. Cost-effectiveness analysis: stress ulcer bleeding prophylaxis with proton pump inhibitors, H2 receptor antagonists Full Text available with Trip Pro

Cost-effectiveness analysis: stress ulcer bleeding prophylaxis with proton pump inhibitors, H2 receptor antagonists Cost-effectiveness analysis: stress ulcer bleeding prophylaxis with proton pump inhibitors, H2 receptor antagonists Cost-effectiveness analysis: stress ulcer bleeding prophylaxis with proton pump inhibitors, H2 receptor antagonists Barkun AN, Adam V, Martel M, Bardou M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS (...) EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary The objective was to assess the cost-effectiveness of two types of drug to prevent stress ulcer bleeding in patients in the intensive care unit. The authors concluded that a proton pump inhibitor was more efficient than a histamine 2-receptor antagonist in preventing bleeding from a stress ulcer

2013 NHS Economic Evaluation Database.

69. Esophageal reflux disease proton pump inhibitor therapy impact on sleep disturbance: a systematic review

Esophageal reflux disease proton pump inhibitor therapy impact on sleep disturbance: a systematic review Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2013 DARE.

70. [Description of the use of Proton Pump Inhibitors (PPIs) in adults covered by the public prescription drug insurance plan]

[Description of the use of Proton Pump Inhibitors (PPIs) in adults covered by the public prescription drug insurance plan] Portrait de l'usage des inhibiteurs de la pompe à protons (IPP) chez les adultes assurés par le régime public d'assurance médicaments [Description of the use of Proton Pump Inhibitors (PPIs) in adults covered by the public prescription drug insurance plan] Portrait de l'usage des inhibiteurs de la pompe à protons (IPP) chez les adultes assurés par le régime public (...) d'assurance médicaments [Description of the use of Proton Pump Inhibitors (PPIs) in adults covered by the public prescription drug insurance plan] L'Institut national d'excellence en sante et en services sociaux (INESSS) Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation L'Institut national d'excellence en sante et en services sociaux (INESSS

2012 Health Technology Assessment (HTA) Database.

71. Review: Proton-pump inhibitors are associated with increased risk for Clostridium difficile infection. (Abstract)

Review: Proton-pump inhibitors are associated with increased risk for Clostridium difficile infection. 22910967 2012 10 19 2012 08 22 1539-3704 157 4 2012 Aug 21 Annals of internal medicine Ann. Intern. Med. ACP Journal Club: review: proton-pump inhibitors are associated with increased risk for Clostridium difficile infection. JC2-13 10.7326/0003-4819-157-4-201208210-02013 Koretz Ronald L RL Olive View-UCLA Medical Center Sylmar, California, USA. eng Comment Journal Article United States Ann

2012 Annals of Internal Medicine

72. Association of Proton Pump Inhibitor Use on Cardiovascular Outcomes With Clopidogrel and Ticagrelor: Insights From the Platelet Inhibition and Patient Outcomes Trial Full Text available with Trip Pro

Association of Proton Pump Inhibitor Use on Cardiovascular Outcomes With Clopidogrel and Ticagrelor: Insights From the Platelet Inhibition and Patient Outcomes Trial The clinical significance of the interaction between clopidogrel and proton pump inhibitors (PPIs) remains unclear.We examined the relationship between PPI use and 1-year cardiovascular events (cardiovascular death, myocardial infarction, or stroke) in patients with acute coronary syndrome randomized to clopidogrel or ticagrelor (...) in a prespecified, nonrandomized subgroup analysis of the Platelet Inhibition and Patient Outcomes (PLATO) trial. The primary end point rates were higher for individuals on a PPI (n=6539) compared with those not on a PPI (n=12 060) at randomization in both the clopidogrel (13.0% versus 10.9%; adjusted hazard ratio [HR], 1.20; 95% confidence interval [CI], 1.04-1.38) and ticagrelor (11.0% versus 9.2%; HR, 1.24; 95% CI, 1.07-1.45) groups. Patients on non-PPI gastrointestinal drugs had similar primary end point

2012 EvidenceUpdates Controlled trial quality: predicted high

73. Effects of proton pump inhibitors on adverse gastrointestinal events in patients receiving clopidogrel: systematic review and meta-analysis

Effects of proton pump inhibitors on adverse gastrointestinal events in patients receiving clopidogrel: systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

74. Use of proton pump inhibitors and risk of hip fracture in relation to dietary and lifestyle factors: a prospective cohort study. Full Text available with Trip Pro

Use of proton pump inhibitors and risk of hip fracture in relation to dietary and lifestyle factors: a prospective cohort study. To examine the association between chronic use of proton pump inhibitors (PPIs) and risk of hip fracture.Prospective cohort study.Nurses' Health Study, which originally recruited from the 11 most populous states in the US.79,899 postmenopausal women enrolled in the Nurses' Health Study who provided data on the use of PPIs and other risk factors biennially since 2000

2012 BMJ

75. Association between proton pump inhibitor therapy and Clostridium difficile infection in a meta-analysis

Association between proton pump inhibitor therapy and Clostridium difficile infection in a meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

76. A meta-analysis of impact of proton pump inhibitors on antiplatelet effect of clopidogrel

A meta-analysis of impact of proton pump inhibitors on antiplatelet effect of clopidogrel Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2012 DARE.

77. Proton pump inhibitors in long-term use: reports of hypomagnesaemia

Proton pump inhibitors in long-term use: reports of hypomagnesaemia Proton pump inhibitors in long-term use: reports of hypomagnesaemia - GOV.UK GOV.UK uses cookies to make the site simpler. or Search Proton pump inhibitors in long-term use: reports of hypomagnesaemia Healthcare professionals should consider measuring magnesium levels before starting PPI treatment and repeat measurements periodically during prolonged treatment. Published 11 December 2014 From: Therapeutic area: Contents Article (...) date: April 2012 Proton pump inhibitors (PPIs) are a class of drugs for the treatment of duodenal and gastric ulcers, and are used in combination with antibacterials for the eradication of Helicobacter pylori. They are also used to treat gastroesophageal reflux disease, dyspepsia, and Zolligner-Ellison syndrome and for prevention and treatment of ulcers associated with the use of non-steroidal anti-inflammatory drugs. The class of PPIs includes esomeprazole (Nexium), lansoprazole (Zoton

2012 MHRA Drug Safety Update

78. Proton pump inhibitors in long-term use: increased risk of fracture

Proton pump inhibitors in long-term use: increased risk of fracture Proton pump inhibitors in long-term use: increased risk of fracture - GOV.UK GOV.UK uses cookies to make the site simpler. or Search Proton pump inhibitors in long-term use: increased risk of fracture Recent epidemiological evidence of an increased risk of fracture with long-term use of proton pump inhibitors (PPIs). Published 11 December 2014 From: Therapeutic area: Contents Article date: April 2012 Observational studies

2012 MHRA Drug Safety Update

79. Cohort study: Patients treated with aspirin after a first myocardial infarction who also receive a proton pump inhibitor have a higher incidence of cardiovascular events

Cohort study: Patients treated with aspirin after a first myocardial infarction who also receive a proton pump inhibitor have a higher incidence of cardiovascular events Patients treated with aspirin after a first myocardial infarction who also receive a proton pump inhibitor have a higher incidence of cardiovascular events | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser (...) infarction who also receive a proton pump inhibitor have a higher incidence of cardiovascular events Article Text Prognosis Cohort study Patients treated with aspirin after a first myocardial infarction who also receive a proton pump inhibitor have a higher incidence of cardiovascular events David N Juurlink Statistics from Altmetric.com Commentary on: Charlot M , Grove EL , Hansen PR , et al . Proton pump inhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time

2012 Evidence-Based Medicine

80. Randomised controlled trial: Laparoscopic antireflux surgery and esomeprazole similarly efficacious for symptoms in people with gastro-oesophageal reflux disease who respond well to proton pump inhibitors Full Text available with Trip Pro

Randomised controlled trial: Laparoscopic antireflux surgery and esomeprazole similarly efficacious for symptoms in people with gastro-oesophageal reflux disease who respond well to proton pump inhibitors Laparoscopic antireflux surgery and esomeprazole similarly efficacious for symptoms in people with gastro-oesophageal reflux disease who respond well to proton pump inhibitors | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you (...) Laparoscopic antireflux surgery and esomeprazole similarly efficacious for symptoms in people with gastro-oesophageal reflux disease who respond well to proton pump inhibitors Article Text Therapeutics Randomised controlled trial Laparoscopic antireflux surgery and esomeprazole similarly efficacious for symptoms in people with gastro-oesophageal reflux disease who respond well to proton pump inhibitors George Triadafilopoulos Statistics from Altmetric.com Commentary on: Galmiche JP , Hatlebakk J , Attwood

2012 Evidence-Based Medicine