Latest & greatest articles for promethazine

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Top results for promethazine

1. Promethazine

Promethazine Top results for promethazine - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4 (...) ) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for promethazine The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you

2018 Trip Latest and Greatest

2. Rapid tranquillisation in mental health settings: promethazine hydrochloride

Rapid tranquillisation in mental health settings: promethazine hydrochloride Rapid tr Rapid tranquillisation in mental health settings: anquillisation in mental health settings: promethazine h promethazine hy ydrochloride drochloride Evidence summary Published: 11 March 2014 nice.org.uk/guidance/esuom28 pathways K Ke ey points from the e y points from the evidence vidence The content of this evidence summary was up-to-date in March 2014. See summaries of product characteristics (SPCs), British (...) national formulary (BNF) or the MHRA or NICE websites for up-to-date information. Summary A Cochrane review (Huf et al. 2009; 4 randomised controlled trials [RCTs], n=1117) provides limited evidence that intramuscular haloperidol plus promethazine is effective for the rapid tranquillisation of people with agitation or aggression associated with mental illness. However, it is difficult to draw any firm conclusions because the results are heterogeneous. In addition, the results were not relevant to UK

2014 National Institute for Health and Clinical Excellence - Advice

3. Promethazine

Promethazine USE OF PROMETHAZINE IN PREGNANCY 0344 892 0909 USE OF PROMETHAZINE IN PREGNANCY (Date of issue: September 2015 , Version: 2 ) This is a UKTIS monograph for use by health care professionals. For case-specific advice please contact UKTIS on 0344 892 0909. To report an exposure please download and complete a . Please encourage all women to complete an . A corresponding patient information leaflet on is available at . Summary (...) patient may be eligible to enrol in a randomised control trial to investigate the best treatment for Hyperemesis Gravidarum (severe pregnancy sickness). Please visit the to find out more. ………………………………………………………………………………………………………………………………………………………… Promethazine is a first generation (sedating) phenothiazine antihistamine used in the treatment of nausea and vomiting, allergy such as hay fever and urticaria, emergency treatment of anaphylactic reactions, and for sedation. Studies (including two small

2014 UK Teratology Information Service

4. Prevention of Opioid-Induced Nausea and Vomiting During Treatment of Moderate to Severe Acute Pain: A Randomized Placebo-Controlled Trial Comparing CL-108 (Hydrocodone 7.5 mg/Acetaminophen 325 mg/Rapid-Release, Low-Dose Promethazine 12.5 mg) with Conventi (Abstract)

Prevention of Opioid-Induced Nausea and Vomiting During Treatment of Moderate to Severe Acute Pain: A Randomized Placebo-Controlled Trial Comparing CL-108 (Hydrocodone 7.5 mg/Acetaminophen 325 mg/Rapid-Release, Low-Dose Promethazine 12.5 mg) with Conventi To evaluate the prevention of opioid-induced nausea and vomiting (OINV) and the relief of moderate to severe acute pain by CL-108, a novel drug combining a low-dose antiemetic (rapid-release promethazine 12.5 mg) with hydrocodone 7.5 mg

2019 EvidenceUpdates

5. Intramuscular haloperidol-promethazine sedates violent or agitated patients more quickly than intramuscular lorazepam Full Text available with Trip Pro

Intramuscular haloperidol-promethazine sedates violent or agitated patients more quickly than intramuscular lorazepam Intramuscular haloperidol-promethazine sedates violent or agitated patients more quickly than intramuscular lorazepam | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Intramuscular haloperidol-promethazine sedates violent or agitated patients more quickly than intramuscular lorazepam Article Text Therapeutics

2006 Evidence-Based Mental Health

6. Haloperidol plus promethazine for psychosis-induced aggression. Full Text available with Trip Pro

Haloperidol plus promethazine for psychosis-induced aggression. Health services often manage agitated or violent people, and such behaviour is particularly prevalent in emergency psychiatric services (10%). The drugs used in such situations should ensure that the person becomes calm swiftly and safely.To examine whether haloperidol plus promethazine is an effective treatment for psychosis-induced aggression.On 6 May 2015 we searched the Cochrane Schizophrenia Group's Register of Trials, which (...) is compiled by systematic searches of major resources (including MEDLINE, EMBASE, AMED, BIOSIS, CINAHL, PsycINFO, PubMed, and registries of clinical trials) and their monthly updates, handsearches, grey literature, and conference proceedings.All randomised clinical trials with useable data focusing on haloperidol plus promethazine for psychosis-induced aggression.We independently extracted data. For binary outcomes, we calculated risk ratio (RR) and its 95% confidence interval (CI), on an intention

2016 Cochrane

7. Ondansetron or promethazine: Which one is better for the treatment of acute peripheral vertigo? (Abstract)

Ondansetron or promethazine: Which one is better for the treatment of acute peripheral vertigo? Vertigo is a common annoying complaint needing emergent treatment. There are various treatment options for this condition with different outcomes and side effects.Assessment and comparison of the effectiveness of Ondansetron and Promethazine in the treatment of acute peripheral vertigo.This clinical trial was conducted in an academic hospital in the north of Iran in 2017. A total of 170 eligible (...) patients were randomly allocated to groups A: received intramuscular (IM) promethazine; and B: received intravenous (IV) Ondansetron, using quadripartite blocks. The severity of vertigo, nausea, blood pressure, heart rate, side-effects, need for re-administration, and the time to become asymptomatic were assessed before the injections, 30 min after and 2 h after the injections.Excellent improvement in vertigo occurred in both groups (P < 0.001), with a more significant reduction in the promethazine

2018 American Journal of Otolaryngology Controlled trial quality: uncertain

8. Promethazine

Promethazine Promethazine Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Promethazine Promethazine Aka: Promethazine , Phenergan From (...) Children: 0.25 to 0.5 mg/kg PO/IM/PR q4-6 hours Maximum: 25 mg per dose VIII. Efficacy Less effective than ( ) in ER patients Sedation may delay Emergency Department discharge IX. References Johnson (1993) Harriet Lane, Mosby, p. 521 (2002) Tarascon Pocket Pharmacopoeia, p. 67 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Promethazine." Click on the image (or right click) to open the source website in a new browser window. Related

2018 FP Notebook

9. A Prospective, Randomized, Double-Blinded, Double-Dummy Pilot Study to Assess the Preemptive Effect of Triple Therapy with Aprepitant, Dexamethasone, and Promethazine versus Ondansetron, Dexamethasone and Promethazine on Reducing the Incidence of Postoper Full Text available with Trip Pro

A Prospective, Randomized, Double-Blinded, Double-Dummy Pilot Study to Assess the Preemptive Effect of Triple Therapy with Aprepitant, Dexamethasone, and Promethazine versus Ondansetron, Dexamethasone and Promethazine on Reducing the Incidence of Postoper Postoperative nausea and vomiting (PONV) is among the most common distressing complications of surgery under anesthesia. Previous studies have demonstrated that patients who undergo craniotomy have incidences of nausea and vomiting as high (...) as 50-70%. The main purpose of this pilot study is to assess the incidence of PONV by using two different prophylactic regimens in subjects undergoing a craniotomy. Thus, we designed this study to assess the efficacy and safety of triple therapy with the combination of dexamethasone, promethazine, and aprepitant versus ondansetron to reduce the incidence of PONV in patients undergoing craniotomy.This is a prospective, single center, two-armed, randomized, double-dummy, double-blind, pilot study

2016 Frontiers in medicine Controlled trial quality: predicted high

10. Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum. Full Text available with Trip Pro

Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum. Hyperemesis gravidarum is the third leading cause of hospitalization during pregnancy. 5-HT3-receptor antagonists are the most effective against chemotherapy-induced nausea and vomiting and radiation. This randomized study aimed to compare and evaluate the efficacies of granisetron and promethazine for controlling nausea and vomiting of pregnancy.The included patients were administered (oral (...) and intravenous) granisetron and promethazine randomly. The patients were evaluated for nausea and vomiting by a senior gynecology resident blinded to designated drugs.This study revealed that granisetron significantly decreased nausea and vomiting in pregnant women (p < 0.05). Greater patient satisfaction and lesser adverse drug reactions in women receiving granisetron observed in this study suggest that it can be introduced as a more effective and safer drug in comparison with promethazine.Considering

2016 Journal of obstetrics and gynaecology of India Controlled trial quality: uncertain

11. Comparison of the efficacy of adding clonidine, chlorpromazine, promethazine, and midazolam to morphine pumps in postoperative pain control of addicted patients. Full Text available with Trip Pro

Comparison of the efficacy of adding clonidine, chlorpromazine, promethazine, and midazolam to morphine pumps in postoperative pain control of addicted patients. Addicted patients present difficulties for pain management because they have another problem besides their pain. Adding adjuvants to opioid pumps to intensify quality, control other problems, lengthen analgesia, and reduce side effects has been considered in the field.The objective of this study was to evaluate the analgesic effects (...) of adding clonidine, promethazine, chlorpromazine, and midazolam to morphine in patient-controlled intravenous analgesia (PCIA) in orthopedic patients with addiction problems.90 patients with histories of substance abuse were enrolled in this randomized controlled trial. Patients were randomly divided into three groups. The first group received 20 mg of morphine sulfate +50 mg of chlorpromazine + 50 mg of promethazine +10 mg of midazolam (M20P). The second group received the first group's regimen plus

2015 Anesthesiology and pain medicine Controlled trial quality: uncertain

12. Promethazine and Oral Midazolam Preanesthetic Children Medication. (Abstract)

Promethazine and Oral Midazolam Preanesthetic Children Medication. Several kinds of drugs have been investigated in preschool children as a preanesthetic sedation after various routes of administration for surgeries. This study aims to compare the efficacy of promethazine and oral midazolam for premedication in children aged 3 to 9 years who were scheduled for surgeries.This is a double-blind randomized controlled study conducted on 93 patients between the age of 3 and 9 years at Loresten (...) University of Medical Sciences Teaching Hospital, Khoramabad, Iran. The subjects were grouped into P (promethazine), M (midazolam), and C (control). About 0.3 mg/kg of oral promethazine was administered to patients in group P, 0.5 mg/kg of oral midazolam was administered to patients in group M, and 3 mL of normal saline as placebo was administered to patients in group C. Patient satisfaction, sedation and emotional score, systolic blood pressure (SBP), diastolic blood pressure, respiratory rate (RR

2018 Pediatric Emergency Care Controlled trial quality: uncertain

13. Comparison Effect of Promethazine/Dexamethasone and Metoclopramide /Dexamethasone on Postoperative Nausea and Vomiting after Laparascopic Gastric Placation: A Randomized Clinical Trial Full Text available with Trip Pro

Comparison Effect of Promethazine/Dexamethasone and Metoclopramide /Dexamethasone on Postoperative Nausea and Vomiting after Laparascopic Gastric Placation: A Randomized Clinical Trial Laparoscopic gastric plication (LGP) is a technique in the restrictive category of bariatric procedures that reduces the gastric volume and increases intragastric pressure. Nausea and vomiting are the most common complications after this procedure. The goal of this research is to compare the combined effect (...) of promethazine/dexamethasone versus Metoclopramide/ dexamethasone on the prevention of nausea and vomiting after LGP.In recovery, the patients were divided into two groups, the Metoclopramide group which was given Metoclopramide 10 mg plus dexamethasone 4 mg/8 hours intravenous for 48 hours, and the promethazine group which was given promethazine 50 mg /12 hours, intramuscular for the first 24 hours and then promethazine 25 mg/12 hours for the next 24 hours plus dexamethasone 4 mg/8 hours intravenous for 48

2017 Anesthesiology and pain medicine Controlled trial quality: uncertain

14. Ondansetron versus promethazine to treat acute undifferentiated nausea in the emergency department: a randomized, double-blind, noninferiority trial (Abstract)

Ondansetron versus promethazine to treat acute undifferentiated nausea in the emergency department: a randomized, double-blind, noninferiority trial The authors sought to compare ondansetron and promethazine among emergency department (ED) patients with undifferentiated nausea. The hypothesis was that ondansetron was not inferior to promethazine and that rates of adverse effects were similar.This was a randomized double-blind noninferiority clinical trial conducted in an urban academic ED (...) . A convenience sample of nonpregnant adults with at least 40 mm of self-reported nausea measured on a 100-mm visual analog scale (VAS) were enrolled. Patients who had already received more than 1 L of intravenous fluid or an antiemetic agent were excluded. Subjects were block-randomized in groups of 10 to either 4 mg of ondansetron or 25 mg of promethazine delivered intravenously. The primary outcome was change in nausea over 30 minutes. The authors used a 15-mm margin of noninferiority. Secondary endpoints

2008 EvidenceUpdates Controlled trial quality: predicted high

15. Promethazine

Promethazine Promethazine Toggle navigation Brain Head & Neck Chest Endocrine Abdomen Musculoskeletal Skin Infectious Disease Hematology & Oncology Cohorts Diagnostics Emergency Findings Procedures Prevention & Management Pharmacy Resuscitation Trauma Emergency Procedures Ultrasound Cardiovascular Emergencies Lung Emergencies Infectious Disease Pediatrics Neurologic Emergencies Skin Exposure Miscellaneous Abuse Cancer Administration 4 Promethazine Promethazine Aka: Promethazine , Phenergan From (...) Children: 0.25 to 0.5 mg/kg PO/IM/PR q4-6 hours Maximum: 25 mg per dose VIII. Efficacy Less effective than ( ) in ER patients Sedation may delay Emergency Department discharge IX. References Johnson (1993) Harriet Lane, Mosby, p. 521 (2002) Tarascon Pocket Pharmacopoeia, p. 67 Images: Related links to external sites (from Bing) These images are a random sampling from a Bing search on the term "Promethazine." Click on the image (or right click) to open the source website in a new browser window. Related

2015 FP Notebook

16. Efficacy of Low Dose Promethazine for Postoperative Nausea and Vomiting

Efficacy of Low Dose Promethazine for Postoperative Nausea and Vomiting Efficacy of Low Dose Promethazine for Postoperative Nausea and Vomiting - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before adding more. Efficacy (...) of Low Dose Promethazine for Postoperative Nausea and Vomiting The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01159548 Recruitment Status : Terminated (Population of interest was no longer available) First Posted : July 9, 2010 Last Update Posted : July 27, 2011 Sponsor: Women's College Hospital

2010 Clinical Trials

17. Comparison of Ondansetron, Metoclopramide and Promethazine for the Treatment of Nausea and Vomiting in the Adult ED

Comparison of Ondansetron, Metoclopramide and Promethazine for the Treatment of Nausea and Vomiting in the Adult ED Comparison of Ondansetron, Metoclopramide and Promethazine for the Treatment of Nausea and Vomiting in the Adult ED - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number (...) of saved studies (100). Please remove one or more studies before adding more. Comparison of Ondansetron, Metoclopramide and Promethazine for the Treatment of Nausea and Vomiting in the Adult ED The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT00655642 Recruitment Status : Terminated (Conditional analysis

2008 Clinical Trials

18. Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment

Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment - Full Text View - ClinicalTrials.gov Hide glossary Glossary Study record managers: refer to the if submitting registration or results information. Search for terms x × Study Record Detail Saved Studies Save this study Warning You have reached the maximum number of saved studies (100). Please remove one or more studies before (...) adding more. Efficacy and Safety of Oral Sumatriptan Plus Oral Promethazine in Migraine Treatment The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our for details. ClinicalTrials.gov Identifier: NCT01814189 Recruitment Status : Completed First Posted : March 19, 2013 Last Update Posted : July 30, 2013 Sponsor: Shahid Beheshti University of Medical

2013 Clinical Trials

19. Comparison of the antiemetics metoclopramide and promethazine in labour. Full Text available with Trip Pro

Comparison of the antiemetics metoclopramide and promethazine in labour. A double blind trial was conducted in 477 mothers in labour to compare the antiemetics metoclopramide 10 mg and promethazine 25 mg and placebo when added to the first dose of pethidine. Metoclopramide and promethazine were equally effective, and both better than placebo, in reducing the incidence of nausea and vomiting after the administration of pethidine. Seventy seven per cent of mothers were drowsy, and 8% slept (...) in the hour after the pethidine injection, with no difference between the groups. The sedative effect was more persistent in the promethazine group, 66% of whom were still drowsy after delivery. One third of the mothers in each group needed further analgesia, with 77% of these ultimately requesting an epidural. The reduction in pain half an hour and one hour after pethidine, assessed by a visual analogue scale, were, respectively, 22% and 22% for placebo; 26% and 23% for metoclopramide; 13% and 9

1985 British medical journal (Clinical research ed.) Controlled trial quality: uncertain

20. [Midazolam and pethidine/promethazine for intramuscular premedication]. (Abstract)

[Midazolam and pethidine/promethazine for intramuscular premedication]. The main reason for premedication is the reduction of preoperative stress. Despite the proven fact that benzodiazepines best reduce preoperative stress, combinations of opioids and neuroleptic drugs are preferred for premedication by many on reviewing the journal Der Anaesthesist. This double-blind study was performed to investigate midazolam and meperidine/promethazine for intramuscular premedication. Method. 60 patients (...) undergoing minor gynecological surgery were randomly assigned to receive either 5-7.5 mg midazolam or 50-75 mg meperidine and 25-50 mg promethazine intramuscularly 30-90 min before surgery. Anxiety, depression, and asthenia were assessed by the patient before and after premedication but before induction of anesthesia using visual analogue scales and a nominal scale. Sedation was assessed by an observer. Heart rate and blood pressure were the physiological stress parameters. Parameters of acceptance

1987 Der Anaesthesist Controlled trial quality: uncertain