Latest & greatest articles for promethazine

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Top results for promethazine

1. Promethazine

Promethazine Top results for promethazine - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4 (...) ) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for promethazine The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you

2018 Trip Latest and Greatest

2. Prevention of Opioid-Induced Nausea and Vomiting During Treatment of Moderate to Severe Acute Pain: A Randomized Placebo-Controlled Trial Comparing CL-108 (Hydrocodone 7.5 mg/Acetaminophen 325 mg/Rapid-Release, Low-Dose Promethazine 12.5 mg) with Conventi (Abstract)

Prevention of Opioid-Induced Nausea and Vomiting During Treatment of Moderate to Severe Acute Pain: A Randomized Placebo-Controlled Trial Comparing CL-108 (Hydrocodone 7.5 mg/Acetaminophen 325 mg/Rapid-Release, Low-Dose Promethazine 12.5 mg) with Conventi To evaluate the prevention of opioid-induced nausea and vomiting (OINV) and the relief of moderate to severe acute pain by CL-108, a novel drug combining a low-dose antiemetic (rapid-release promethazine 12.5 mg) with hydrocodone 7.5 mg

2019 EvidenceUpdates

3. Rapid tranquillisation in mental health settings: promethazine hydrochloride

Rapid tranquillisation in mental health settings: promethazine hydrochloride Rapid tr Rapid tranquillisation in mental health settings: anquillisation in mental health settings: promethazine h promethazine hy ydrochloride drochloride Evidence summary Published: 11 March 2014 nice.org.uk/guidance/esuom28 pathways K Ke ey points from the e y points from the evidence vidence The content of this evidence summary was up-to-date in March 2014. See summaries of product characteristics (SPCs), British (...) national formulary (BNF) or the MHRA or NICE websites for up-to-date information. Summary A Cochrane review (Huf et al. 2009; 4 randomised controlled trials [RCTs], n=1117) provides limited evidence that intramuscular haloperidol plus promethazine is effective for the rapid tranquillisation of people with agitation or aggression associated with mental illness. However, it is difficult to draw any firm conclusions because the results are heterogeneous. In addition, the results were not relevant to UK

2014 National Institute for Health and Clinical Excellence - Advice

4. Promethazine

Promethazine USE OF PROMETHAZINE IN PREGNANCY 0344 892 0909 USE OF PROMETHAZINE IN PREGNANCY (Date of issue: September 2015 , Version: 2 ) This is a UKTIS monograph for use by health care professionals. For case-specific advice please contact UKTIS on 0344 892 0909. To report an exposure please download and complete a . Please encourage all women to complete an . A corresponding patient information leaflet on is available at . Summary (...) patient may be eligible to enrol in a randomised control trial to investigate the best treatment for Hyperemesis Gravidarum (severe pregnancy sickness). Please visit the to find out more. ………………………………………………………………………………………………………………………………………………………… Promethazine is a first generation (sedating) phenothiazine antihistamine used in the treatment of nausea and vomiting, allergy such as hay fever and urticaria, emergency treatment of anaphylactic reactions, and for sedation. Studies (including two small

2014 UK Teratology Information Service

5. Ondansetron versus promethazine to treat acute undifferentiated nausea in the emergency department: a randomized, double-blind, noninferiority trial Full Text available with Trip Pro

Ondansetron versus promethazine to treat acute undifferentiated nausea in the emergency department: a randomized, double-blind, noninferiority trial The authors sought to compare ondansetron and promethazine among emergency department (ED) patients with undifferentiated nausea. The hypothesis was that ondansetron was not inferior to promethazine and that rates of adverse effects were similar.This was a randomized double-blind noninferiority clinical trial conducted in an urban academic ED (...) . A convenience sample of nonpregnant adults with at least 40 mm of self-reported nausea measured on a 100-mm visual analog scale (VAS) were enrolled. Patients who had already received more than 1 L of intravenous fluid or an antiemetic agent were excluded. Subjects were block-randomized in groups of 10 to either 4 mg of ondansetron or 25 mg of promethazine delivered intravenously. The primary outcome was change in nausea over 30 minutes. The authors used a 15-mm margin of noninferiority. Secondary endpoints

2008 EvidenceUpdates Controlled trial quality: predicted high

6. Haloperidol plus promethazine effective for psychosis induced aggression

Haloperidol plus promethazine effective for psychosis induced aggression Haloperidol plus promethazine effective for psychosis induced aggression | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username (...) * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Haloperidol plus promethazine effective for psychosis induced aggression Article Text Therapeutics Haloperidol plus promethazine effective for psychosis induced aggression Statistics from Altmetric.com Question Question: Is haloperidol plus

2010 Evidence-Based Mental Health

7. Tranquilising agitated mentally ill patients: intramuscular haloperidol plus promethazine reduces need for additional medication or medical attention compared to olanzapine

Tranquilising agitated mentally ill patients: intramuscular haloperidol plus promethazine reduces need for additional medication or medical attention compared to olanzapine Tranquilising agitated mentally ill patients: intramuscular haloperidol plus promethazine reduces need for additional medication or medical attention compared to olanzapine | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie (...) patients: intramuscular haloperidol plus promethazine reduces need for additional medication or medical attention compared to olanzapine Article Text Therapeutics Tranquilising agitated mentally ill patients: intramuscular haloperidol plus promethazine reduces need for additional medication or medical attention compared to olanzapine Statistics from Altmetric.com Request Permissions If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance

2008 Evidence-Based Mental Health

8. Promethazine and Oral Midazolam Preanesthetic Children Medication. (Abstract)

Promethazine and Oral Midazolam Preanesthetic Children Medication. Several kinds of drugs have been investigated in preschool children as a preanesthetic sedation after various routes of administration for surgeries. This study aims to compare the efficacy of promethazine and oral midazolam for premedication in children aged 3 to 9 years who were scheduled for surgeries.This is a double-blind randomized controlled study conducted on 93 patients between the age of 3 and 9 years at Loresten (...) University of Medical Sciences Teaching Hospital, Khoramabad, Iran. The subjects were grouped into P (promethazine), M (midazolam), and C (control). About 0.3 mg/kg of oral promethazine was administered to patients in group P, 0.5 mg/kg of oral midazolam was administered to patients in group M, and 3 mL of normal saline as placebo was administered to patients in group C. Patient satisfaction, sedation and emotional score, systolic blood pressure (SBP), diastolic blood pressure, respiratory rate (RR

2018 Pediatric Emergency Care Controlled trial quality: uncertain

9. Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum. Full Text available with Trip Pro

Comparison of Efficacy of Granisetron and Promethazine in Control of Hyperemesis Gravidarum. Hyperemesis gravidarum is the third leading cause of hospitalization during pregnancy. 5-HT3-receptor antagonists are the most effective against chemotherapy-induced nausea and vomiting and radiation. This randomized study aimed to compare and evaluate the efficacies of granisetron and promethazine for controlling nausea and vomiting of pregnancy.The included patients were administered (oral (...) and intravenous) granisetron and promethazine randomly. The patients were evaluated for nausea and vomiting by a senior gynecology resident blinded to designated drugs.This study revealed that granisetron significantly decreased nausea and vomiting in pregnant women (p < 0.05). Greater patient satisfaction and lesser adverse drug reactions in women receiving granisetron observed in this study suggest that it can be introduced as a more effective and safer drug in comparison with promethazine.Considering

2016 Journal of obstetrics and gynaecology of India Controlled trial quality: uncertain

10. Comparison of Haloperidol, Promethazine, Trifluoperazine, and Chlorpromazine in Terms of Velocity and Durability of the Sedation among Acute Aggressive Patients: A Randomized Clinical Trial. Full Text available with Trip Pro

Comparison of Haloperidol, Promethazine, Trifluoperazine, and Chlorpromazine in Terms of Velocity and Durability of the Sedation among Acute Aggressive Patients: A Randomized Clinical Trial. Knowledge and skill about sedation of aggressive patients is necessary for each psychiatrist. The purpose of this study was comparing the velocity and durability of sedation induced by the haloperidol, trifluoperazine, promethazine, and chlorpromazine in aggressive patients.This randomized clinical trial (...) was done on 76 aggressive patients referred to Psychiatry Emergency Service of Noor Hospital of Isfahan University of Medical Sciences that were randomly divided into four groups of haloperidol, promethazine, chlorpromazine, and trifluoperazine. Patients were evaluated at 30 min intervals for aggressive symptoms, and if they did not respond to intervention after the first 30 min or if they showed aggression again, a same dose of the injected drug was prescribed. The length of sedation time was recorded

2019 Advanced biomedical research Controlled trial quality: uncertain

11. Nausea/vomiting in pregnancy: Promethazine

Nausea/vomiting in pregnancy: Promethazine Promethazine | Prescribing information | Nausea/vomiting in pregnancy | CKS | NICE Search CKS… Menu Promethazine Nausea/vomiting in pregnancy: Promethazine Last revised in February 2020 Promethazine What dosage of promethazine should I prescribe? Promethazine is available as promethazine hydrochloride or promethazine teoclate. Either preparation may be used: Promethazine hydrochloride is available in two strengths — 10 mg or 25 mg tablets. Prescribe (...) up to 25 mg as one dose at bedtime, and repeat in the morning if necessary. Promethazine teoclate is available as 25 mg tablets. Prescribe 25 mg at bedtime. The dose may be increased to 100 mg daily. What are the adverse effects of promethazine? Adverse effects of promethazine include: Neurological — dizziness, confusion, headaches, nightmares, sedation which can persist for up to 12 hours (affected people should not drive or operate heavy machinery), muscle spasms and tic-like movements

2018 NICE Clinical Knowledge Summaries

12. Acute onset of orofacial dystonia from promethazine treatment: A case report. Full Text available with Trip Pro

Acute onset of orofacial dystonia from promethazine treatment: A case report. Promethazine is an antihistamine agent used commonly for nausea and allergy. Along with its anticholinergic and antidopaminergic functions, promethazine is also used for psychiatric symptoms, such as troubling sleep, anxiety, and agitation. Previous studies have reported that promethazine may occasionally elicit acute dystonia in some individuals, especially for young children and pregnant women.The 68-year-old female (...) patient was admitted to our hospital because of feeling anxious and intermittent palpitation for over 1 year. She developed acute orofacial dystonia following promethazine treatment.Her diagnoses was generalized anxiety disorder.Discontinuation of the offending agent, promethazine, and injection of Botulinum toxin.The acute orofacial dystonia was finally alleviated by local injection of Botulinum toxin.Careful assessment of the risk of developing acute dystonia is also needed in old patients when

2019 Medicine

13. Comparison Effect of Promethazine/Dexamethasone and Metoclopramide /Dexamethasone on Postoperative Nausea and Vomiting after Laparascopic Gastric Placation: A Randomized Clinical Trial Full Text available with Trip Pro

Comparison Effect of Promethazine/Dexamethasone and Metoclopramide /Dexamethasone on Postoperative Nausea and Vomiting after Laparascopic Gastric Placation: A Randomized Clinical Trial Laparoscopic gastric plication (LGP) is a technique in the restrictive category of bariatric procedures that reduces the gastric volume and increases intragastric pressure. Nausea and vomiting are the most common complications after this procedure. The goal of this research is to compare the combined effect (...) of promethazine/dexamethasone versus Metoclopramide/ dexamethasone on the prevention of nausea and vomiting after LGP.In recovery, the patients were divided into two groups, the Metoclopramide group which was given Metoclopramide 10 mg plus dexamethasone 4 mg/8 hours intravenous for 48 hours, and the promethazine group which was given promethazine 50 mg /12 hours, intramuscular for the first 24 hours and then promethazine 25 mg/12 hours for the next 24 hours plus dexamethasone 4 mg/8 hours intravenous for 48

2017 Anesthesiology and pain medicine Controlled trial quality: uncertain

14. Comparison of sedative effects of oral midazolam/chloral hydrate and midazolam/promethazine in pediatric dentistry Full Text available with Trip Pro

Comparison of sedative effects of oral midazolam/chloral hydrate and midazolam/promethazine in pediatric dentistry Background. The aim of this investigation was to compare the sedative effects of oral midazolam/chloral hydrate and midazolam/promethazine combinations on fearful children needing dental treatment. Methods. This crossover double-blind clinical trial was conducted on 30 children aged 2‒6 years, who had at least two similar teeth needing pulp treatment. Standard vital signs were (...) recorded before and after premedication. Wilson sedation scale was used to judge the level of sedation. Cases were divided into two groups based on the sequence of medication received. This was to overcome the sequence effect. Group I received oral midazolam (0.4 mg/kg/chloral hydrate (50 mg/kg) at the first visit while they received midazolam (0.4 mg/kg)/promethazine (5 mg/kg) in their second visit. Group II received the premedication in the opposite sequence. The operator and child were blinded

2018 Journal of dental research, dental clinics, dental prospects Controlled trial quality: uncertain

15. Ondansetron or promethazine: Which one is better for the treatment of acute peripheral vertigo? (Abstract)

Ondansetron or promethazine: Which one is better for the treatment of acute peripheral vertigo? Vertigo is a common annoying complaint needing emergent treatment. There are various treatment options for this condition with different outcomes and side effects.Assessment and comparison of the effectiveness of Ondansetron and Promethazine in the treatment of acute peripheral vertigo.This clinical trial was conducted in an academic hospital in the north of Iran in 2017. A total of 170 eligible (...) patients were randomly allocated to groups A: received intramuscular (IM) promethazine; and B: received intravenous (IV) Ondansetron, using quadripartite blocks. The severity of vertigo, nausea, blood pressure, heart rate, side-effects, need for re-administration, and the time to become asymptomatic were assessed before the injections, 30 min after and 2 h after the injections.Excellent improvement in vertigo occurred in both groups (P < 0.001), with a more significant reduction in the promethazine

2018 American Journal of Otolaryngology Controlled trial quality: uncertain

16. Midazolam sedates agitated patients more rapidly than haloperidol-promethazine Full Text available with Trip Pro

Midazolam sedates agitated patients more rapidly than haloperidol-promethazine Midazolam sedates agitated patients more rapidly than haloperidol-promethazine | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Midazolam sedates agitated patients more rapidly than haloperidol-promethazine Article Text Therapeutics Midazolam sedates agitated patients more rapidly than haloperidol-promethazine Free Paul S Waraich , MHSc MD FRCP(C) Statistics

2005 Evidence-Based Mental Health

17. Intramuscular haloperidol-promethazine sedates violent or agitated patients more quickly than intramuscular lorazepam Full Text available with Trip Pro

Intramuscular haloperidol-promethazine sedates violent or agitated patients more quickly than intramuscular lorazepam Intramuscular haloperidol-promethazine sedates violent or agitated patients more quickly than intramuscular lorazepam | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Intramuscular haloperidol-promethazine sedates violent or agitated patients more quickly than intramuscular lorazepam Article Text Therapeutics

2006 Evidence-Based Mental Health

18. Promethazine exhibits antiparasitic properties <i>in vitro</i> and reduces worm burden, egg production, hepato-, and splenomegaly in a schistosomiasis animal model. Full Text available with Trip Pro

Promethazine exhibits antiparasitic properties in vitro and reduces worm burden, egg production, hepato-, and splenomegaly in a schistosomiasis animal model. The treatment and control of schistosomiasis, a neglected disease that affects more than 200 million people worldwide, rely on the use of a single drug, praziquantel. A vaccine has yet to be developed and since new drug design and development is a lengthy and costly process, drug repurposing is a promising strategy. In this study (...) , the efficacy of promethazine, a first-generation antihistamine, was evaluated against Schistosoma mansoniex vivo and in a murine model of schistosomiasis. In vitro assays demonstrated that promethazine affected parasite motility, viability, and it induced severe tegumental damage in schistosomes. The LC50 of the drug was 5.84 μM. Similar to promethazine, schistosomes incubated with atropine, a classical anticholinergic drug, displayed reduced motor activity. In an animal model, promethazine treatment

2019 Antimicrobial Agents and Chemotherapy

19. Low dose concomitant treatment with chlorpromazine and promethazine is safe in acute ischemic stroke. (Abstract)

Low dose concomitant treatment with chlorpromazine and promethazine is safe in acute ischemic stroke. Acute ischemic stroke (AIS) is associated with significant morbidity and mortality and has a very narrow window of treatment with fibrinolytics. We investigated the safety and efficacy of combined chlorpromazine and promethazine (C+P) treatment in AIS.A total of 64 consecutive patients diagnosed with AIS were selected and were randomly (double-blind) assigned into either the control group (...) differences in those scores between the two group (P>0.05) suggesting no improved benefit with C+P. Moreover, using C+P did not lead to any serious adverse effects when compared to the treatment group.While the addition of low dose chlorpromazine and promethazine to standard of care for acute ischemic stroke did not have any significant improvement in functional outcomes, there were no serious adverse effects. Thus, the use of chlorpromazine and promethazine in the acute ischemic stroke setting and future

2019 Journal Of Neurosurgical Sciences Controlled trial quality: uncertain

20. Promethazine

Promethazine Promethazine - MotherToBaby MotherToBaby Medications and More during pregnancy and breastfeeding Search this website 866.626.6847 . Does taking promethazine increase the chance for a miscarriage? Miscarriage can occur in any pregnancy. One small study did not report an increased chance for miscarriage among women taking promethazine. Does taking promethazine in the first trimester increase the chance of birth defects? In every pregnancy a woman starts out with a 3-5% chance (...) of having a baby with a birth defect. This is called her background risk. Most studies do not suggest that promethazine would increase the chance for birth defects above the background risk when used in the first trimester. Could taking promethazine in the second or third trimester cause other pregnancy complications? Using promethazine late in pregnancy might increase the chance of slowed breathing (respiratory depression) in newborn babies. It is important that your healthcare providers know you

2018 MotherToBaby