Latest & greatest articles for pregnancy

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Top results for pregnancy

1641. The use of aspirin to prevent pregnancy-induced hypertension and lower the ratio of thromboxane A2 to prostacyclin in relatively high risk pregnancies.

The use of aspirin to prevent pregnancy-induced hypertension and lower the ratio of thromboxane A2 to prostacyclin in relatively high risk pregnancies. 2664522 1989 08 22 1989 08 22 2013 11 21 0028-4793 321 6 1989 Aug 10 The New England journal of medicine N. Engl. J. Med. The use of aspirin to prevent pregnancy-induced hypertension and lower the ratio of thromboxane A2 to prostacyclin in relatively high risk pregnancies. 351-6 We carried out a prospective, randomized, double-blind, placebo (...) -controlled study to investigate the capacity of aspirin to prevent pregnancy-induced hypertension and to alter prostaglandin metabolism. A total of 791 pregnant women with various risk factors for pre-eclamptic toxemia were screened with use of the rollover test (a comparison of blood pressure before and after the woman rolls from her left side to her back) during week 28 or 29 of gestation. Of 69 women with abnormal results (an increase in blood pressure during the rollover test), 65 entered the study

NEJM1989

1642. Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension.

Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension. 2664523 1989 08 22 1989 08 22 2013 11 21 0028-4793 321 6 1989 Aug 10 The New England journal of medicine N. Engl. J. Med. Effect of low-dose aspirin on fetal and maternal generation of thromboxane by platelets in women at risk for pregnancy-induced hypertension. 357-62 There is evidence that aspirin in low doses favorably influences the course of pregnancy (...) -induced hypertension, but the mechanism, although assumed to involve suppression of the production of thromboxane by platelets, has not been established. We performed a randomized study of the effect of the long-term daily administration of 60 mg of aspirin (n = 17) or placebo (n = 16) on platelet thromboxane A2 and vascular prostacyclin in women at risk for pregnancy-induced hypertension. Low doses of aspirin were associated with a longer pregnancy and increased weight of newborns. Serum levels

NEJM1989

1643. Zinc supplementation during pregnancy: a double blind randomised controlled trial.

Zinc supplementation during pregnancy: a double blind randomised controlled trial. 2510845 1989 12 26 1989 12 26 2013 11 21 0959-8138 299 6703 1989 Sep 30 BMJ (Clinical research ed.) BMJ Zinc supplementation during pregnancy: a double blind randomised controlled trial. 826-30 To see whether zinc supplementation during pregnancy improves maternal and fetal outcome. Prospective study started at booking and continued till discharge of mother and baby from the maternity hospital. Mothers were (...) randomly assigned to receive zinc supplementation or placebo in a double blind trial. Mothers booking at one hospital. Women booking before 20 weeks of gestation who agreed to take part in the study. 494 Mothers were followed up till the end of pregnancy. There was no difference between the groups given zinc and placebo in their social or medical backgrounds. Mothers in the active treatment group received one capsule of 20 mg elemental zinc daily and those in the placebo treated group a capsule

BMJ1989 Full Text: Link to full Text with Trip Pro

1644. Effects of routine one-stage ultrasound screening in pregnancy: a randomised controlled trial.

Effects of routine one-stage ultrasound screening in pregnancy: a randomised controlled trial. 2900977 1988 10 04 1988 10 04 2015 06 16 0140-6736 2 8611 1988 Sep 10 Lancet (London, England) Lancet Effects of routine one-stage ultrasound screening in pregnancy: a randomised controlled trial. 585-8 4997 of 7354 pregnant women had no clinical indication for an elective ultrasound examination at 12 weeks' gestation. 2482 of these women were randomly selected for ultrasound screening at 15 weeks (...) and the remainder received the same standard antenatal care without the scan. Labour was less often induced among screened women both for all reasons (5.9% vs 9.1%, p less than 0.0001) and for suspected post-term pregnancy (1.7% vs 3.7%, p less than 0.0001). Earlier detection of twins had no effect on neonatal outcome. Among babies born to screened women, fewer were of birthweight less than 2500 g (59 vs 95, p = 0.005) and mean birthweight was 42 g higher (p 0.008). For babies born to screened women who smoked

Lancet1988

1645. Umbilical artery flow velocity waveforms in high-risk pregnancy. Randomised controlled trial.

Umbilical artery flow velocity waveforms in high-risk pregnancy. Randomised controlled trial. 2880017 1987 03 02 1987 03 02 2015 06 16 0140-6736 1 8526 1987 Jan 24 Lancet (London, England) Lancet Umbilical artery flow velocity waveforms in high-risk pregnancy. Randomised controlled trial. 188-90 300 patients at high fetal risk (mean gestational age 34 wk) were randomised to a group for antenatal doppler umbilical artery waveform studies and a control group. The timing of delivery was similar (...) in the control and doppler-report-available groups overall. However, in the report group obstetricians allowed the pregnancies of those not selected for elective delivery to continue longer. There was no difference in the rates for elective delivery (induction of labour or caesarean section) in the two groups, whereas among those who went into labour (induced or spontaneous) emergency caesarean section was more frequent in the control group (23%) than in the report group (13%). Fetal distress in labour

Lancet1987

1646. Effect of cyclosporin, previous third-party transfusion, and pregnancy on antibody development after donor-specific transfusion before renal transplantation.

Effect of cyclosporin, previous third-party transfusion, and pregnancy on antibody development after donor-specific transfusion before renal transplantation. 2880218 1987 03 24 1987 03 24 2015 06 16 0140-6736 1 8530 1987 Feb 21 Lancet (London, England) Lancet Effect of cyclosporin, previous third-party transfusion, and pregnancy on antibody development after donor-specific transfusion before renal transplantation. 416-8 Non-cytotoxic and cytotoxic antibodies were sought after donor-specific (...) Formation drug effects Blood Donors Blood Transfusion Cyclosporins pharmacology Evaluation Studies as Topic Female Humans Immunization Kidney Transplantation Parity Pregnancy immunology Premedication Prospective Studies Receptors, Fc immunology T-Lymphocytes, Cytotoxic immunology Time Factors Tissue Donors 1987 2 21 1987 2 21 0 1 1987 2 21 0 0 ppublish 2880218 S0140-6736(87)90121-8

Lancet1987

1647. A randomized clinical trial of the insulin pump vs intensive conventional therapy in diabetic pregnancies.

A randomized clinical trial of the insulin pump vs intensive conventional therapy in diabetic pregnancies. 3511311 1986 02 28 1986 02 28 2016 10 17 0098-7484 255 5 1986 Feb 07 JAMA JAMA A randomized clinical trial of the insulin pump vs intensive conventional therapy in diabetic pregnancies. 631-6 Improved perinatal outcome is associated with the prevention of hyperglycemia during pregnancy in diabetic women. To determine whether the method of insulin administration influences the degree (...) of diabetic control obtained, we randomized 22 pregnant diabetic women to intensive conventional insulin therapy (N = 11) and insulin pump therapy (N = 11). Frequent outpatient visits; home glucose monitoring, at least six times daily; and frequent telephone contact were offered to all subjects. Patients were hospitalized in the inpatient clinical research center each trimester for a 24-hour metabolic profile. There were no differences between the two treatment groups with respect to outpatient mean

JAMA1986

1648. Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae.

Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae. 2867260 1986 02 06 1986 02 06 2015 06 16 0140-6736 1 8471 1986 Jan 04 Lancet (London, England) Lancet Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae. 1-3 The possibility of preventing pregnancy-induced hypertension (PIH) and pre-eclampsia in primigravidae by suppressing production of thromboxane A2 with low-dose (...) II administration & dosage pharmacology Aspirin administration & dosage Blood Pressure drug effects Clinical Trials as Topic Double-Blind Method Female Humans Hypertension prevention & control Infant, Newborn Infusions, Parenteral Male Malondialdehyde analysis Pre-Eclampsia prevention & control Pregnancy Pregnancy Complications, Cardiovascular prevention & control Random Allocation 1986 1 4 1986 1 4 0 1 1986 1 4 0 0 ppublish 2867260 S0140-6736(86)91891-X

Lancet1986

1649. The effects of hospital admission for bed rest on the duration of twin pregnancy: a randomised trial.

The effects of hospital admission for bed rest on the duration of twin pregnancy: a randomised trial. 2864530 1985 11 19 1985 11 19 2015 06 16 0140-6736 2 8459 1985 Oct 12 Lancet (London, England) Lancet The effects of hospital admission for bed rest on the duration of twin pregnancy: a randomised trial. 793-5 212 women with twin pregnancies were randomly allocated either to receive advice to rest in hospital from 32 weeks' gestation until delivery, or to be part of a control group in which (...) Randomized Controlled Trial Research Support, Non-U.S. Gov't England Lancet 2985213R 0140-6736 AIM IM Adult Bed Rest Clinical Trials as Topic Female Hospitalization Humans Obstetric Labor, Premature prevention & control Pregnancy Pregnancy, Multiple Prenatal Care methods Random Allocation 1985 10 12 1985 10 12 0 1 1985 10 12 0 0 ppublish 2864530 S0140-6736(85)90792-5

Lancet1985

1650. Randomised controlled trial of ultrasonographic screening in pregnancy.

Randomised controlled trial of ultrasonographic screening in pregnancy. 6146762 1984 08 30 1984 08 30 2015 06 16 0140-6736 2 8396 1984 Jul 28 Lancet (London, England) Lancet Randomised controlled trial of ultrasonographic screening in pregnancy. 207-11 510 of 1009 pregnant women in the Trondheim area (Norway) were randomly selected for ultrasound examination at the 19th and 32nd weeks of pregnancy in addition to routine antenatal care. Among the screened women, twins were diagnosed earlier (...) and there were slightly fewer post-term inductions (2.8% versus 4.0%) and fewer low-weight births (2.2% versus 3.6% less than 2500 g), but none of these differences was statistically significant. There were no differences in the condition of the newborn. Small-for-gestational-age births were more often diagnosed antenatally in the screened group and the mothers received more active treatment. During pregnancy, screened women were admitted to hospital more often than unscreened women (15.5% versus 9.2

Lancet1984

1651. The effect of covert bacteriuria in schoolgirls on renal function at 18 years and during pregnancy.

The effect of covert bacteriuria in schoolgirls on renal function at 18 years and during pregnancy. 6147691 1984 10 25 1984 10 25 2015 06 16 0140-6736 2 8404 1984 Sep 22 Lancet (London, England) Lancet The effect of covert bacteriuria in schoolgirls on renal function at 18 years and during pregnancy. 651-5 Schoolgirls shown to have covert bacteriuria (CB) by a screening programme and followed up for 5 years to assess whether chemotherapy had any beneficial effect, underwent a further assessment (...) of renal function at the age of 18 years and during subsequent pregnancies. At age 18, glomerular filtration rate (GFR) and urine concentrating ability were the same as in controls, but fractional reabsorption of glucose was significantly reduced in those who had previously been prescribed chemotherapy because of renal scarring or who had been randomly allocated not to receive prophylactic chemotherapy. Those who had had CB as schoolgirls had a higher frequency of CB in pregnancy than did controls

Lancet1984

1652. Placebo-controlled trial of atenolol in treatment of pregnancy-associated hypertension.

Placebo-controlled trial of atenolol in treatment of pregnancy-associated hypertension. 6131164 1983 04 21 1983 04 21 2015 06 16 0140-6736 1 8322 1983 Feb 26 Lancet (London, England) Lancet Placebo-controlled trial of atenolol in treatment of pregnancy-associated hypertension. 431-4 Atenolol was compared with placebo in a randomised and double-blind prospective study of 120 women with mild to moderate pregnancy-associated hypertension who were also initially managed conventionally by bed rest (...) Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't England Lancet 2985213R 0140-6736 0 Propanolamines 50VV3VW0TI Atenolol AIM IM Adult Atenolol pharmacology therapeutic use Bed Rest Blood Pressure drug effects Clinical Trials as Topic Double-Blind Method Female Humans Hypertension drug therapy therapy Infant, Newborn Maternal-Fetal Exchange Pregnancy Pregnancy Complications, Cardiovascular drug therapy therapy Pregnancy Trimester, Third Propanolamines therapeutic use

Lancet1983

1653. Final report of study on hypertension during pregnancy: the effects of specific treatment on the growth and development of the children.

Final report of study on hypertension during pregnancy: the effects of specific treatment on the growth and development of the children. 6121965 1982 06 21 1982 06 21 2015 06 16 0140-6736 1 8273 1982 Mar 20 Lancet (London, England) Lancet Final report of study on hypertension during pregnancy: the effects of specific treatment on the growth and development of the children. 647-9 195 (97.5%) children born to hypertensive women participating in a trial of methyldopa treatment during pregnancy (...) , but there was no difference in mean intelligence quotients. There were no significant differences between the children in the treated and untreated groups in standing and supine blood pressures, or fourteen tests of ability. Methyldopa therefore seems safe to use in pregnancy and is probably preferable to other drugs from the point of view of the neonate and child. Cockburn J J Moar V A VA Ounsted M M Redman C W CW eng Clinical Trial Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't England

Lancet1982

1654. Cigarette smoking in pregnancy: Associations with maternal weight gain and fetal growth.

Cigarette smoking in pregnancy: Associations with maternal weight gain and fetal growth. 55649 1976 04 27 1976 04 27 2015 06 16 0140-6736 1 7956 1976 Feb 21 Lancet (London, England) Lancet Cigarette smoking in pregnancy: Associations with maternal weight gain and fetal growth. 385-7 1159 mother-infant "pairs" have been studied to examine the inter-relationship of cigarette smoking in the latter half of pregnancy, maternal weight gain, and fetal growth. Non-smokers gained significantly more (...) Exchange Pregnancy Sex Factors Sex Ratio Smoking 1976 2 21 1976 2 21 0 1 1976 2 21 0 0 ppublish 55649 S0140-6736(76)90215-4

Lancet1976

1655. Plasma-urate measurements in predicting fetal death in hypertensive pregnancy.

Plasma-urate measurements in predicting fetal death in hypertensive pregnancy. 59013 1976 08 23 1976 08 23 2015 06 16 0140-6736 1 7974 1976 Jun 26 Lancet (London, England) Lancet Plasma-urate measurements in predicting fetal death in hypertensive pregnancy. 1370-3 The relation of perinatal mortality to plasma-urate concentrations and blood-pressure was studied in 332 pregnant patients with hypertension. Perinatal mortality was markedly increased when maternal plasma-urate concentrations were (...) important feature of pre-eclampsia than the hypertension. Redman C W CW Beilin L J LJ Bonnar J J Wilkinson R H RH eng Clinical Trial Journal Article Randomized Controlled Trial England Lancet 2985213R 0140-6736 268B43MJ25 Uric Acid AIM IM Blood Pressure Chronic Disease Female Fetal Death etiology Gestational Age Glomerular Filtration Rate Humans Hypertension complications Infant, Newborn Infant, Newborn, Diseases mortality Kidney physiopathology Pre-Eclampsia blood Pregnancy Pregnancy Complications

Lancet1976

1656. Fetal outcome in trial of antihypertensive treatment in pregnancy.

Fetal outcome in trial of antihypertensive treatment in pregnancy. 61439 1976 12 01 1976 12 01 2015 06 16 0140-6736 2 7989 1976 Oct 09 Lancet (London, England) Lancet Fetal outcome in trial of antihypertensive treatment in pregnancy. 753-6 242 women completed a controlled trial of methyldopa ('Aldomet') for moderate hypertension in pregnancy. Active treatment was associated with a significantly improved fetal outcome, due in part to a reduced number of mid-pregnancy abortions. There were 9 (...) pregnancy losses in the control group, which included 4 mid-pregnancy abortions, and 1 fetal loss in the treated group. The birthweight and maturity of viable infants were similar in treated and control groups, and a detailed multivariate analysis confirmed that hypotensive treatment had no effect on fetal growth in utero. The better outcome associated with treatment was not due to the prevention of pre-eclampsia, and may be partly due to a direct or indirect effect of methyldopa on uterine activity

Lancet1976