Latest & greatest articles for pregnancy

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on pregnancy or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on pregnancy and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for pregnancy

81. Successful management of cesarean scar pregnancy with vacuum extraction under ultrasound guidance (PubMed)

Successful management of cesarean scar pregnancy with vacuum extraction under ultrasound guidance 30338082 2018 11 14 2052-8817 5 4 2018 Oct Acute medicine & surgery Acute Med Surg Successful management of cesarean scar pregnancy with vacuum extraction under ultrasound guidance. 358-361 10.1002/ams2.362 Cesarean scar pregnancy (CSP) is a rare type of ectopic pregnancy. The gestational sac is implanted in the myometrium at the site of a previous cesarean section. Mothers with CSP are faced (...) anesthesia, with patients in the lithotomy position, using suprapubic ultrasonography guidance. A vacuum aspirator was used to aspirate the whole pregnancy material without perforating the previous cesarean section scar. Ten women with CSP were managed successfully by ultrasound-guided vacuum extraction without complications or further interventions, such as reoperation or methotrexate administration. Three of the 10 patients needed uterine Foley catheter tampon (50 cc) for 4 h after vacuum extraction

Full Text available with Trip Pro

2018 Acute medicine & surgery

82. The impact of endometrial thickness (EMT) on the day of human chorionic gonadotropin (hCG) administration on pregnancy outcomes: a 5-year retrospective cohort analysis in Malaysia (PubMed)

The impact of endometrial thickness (EMT) on the day of human chorionic gonadotropin (hCG) administration on pregnancy outcomes: a 5-year retrospective cohort analysis in Malaysia 30116547 2018 11 14 2054-7099 4 2018 Fertility research and practice Fertil Res Pract The impact of endometrial thickness (EMT) on the day of human chorionic gonadotropin (hCG) administration on pregnancy outcomes: a 5-year retrospective cohort analysis in Malaysia. 5 10.1186/s40738-018-0050-8 Chances of pregnancy (...) in relation to endometrial thickness (EMT) remain elusive albeit some literatures suggest poorer pregnancy outcomes below the threshold of 6-7 mm, notwithstanding others perceive detrimental effect at thicker EMT. We aim to examine the implication of EMT on pregnancy outcomes using a cut-off of 8 mm and further explore for any effect of 'thick' EMT in our patient population. This was a retrospective cohort study performed for 162 women to assess the associations between EMT on the human chorionic

Full Text available with Trip Pro

2018 Fertility research and practice

83. Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth. (PubMed)

Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth. Background It is unclear whether maternal vitamin D supplementation during pregnancy and lactation improves fetal and infant growth in regions where vitamin D deficiency is common. Methods We conducted a randomized, double-blind, placebo-controlled trial in Bangladesh to assess the effects of weekly prenatal vitamin D supplementation (from 17 to 24 weeks of gestation until birth) and postpartum vitamin D supplementation (...) (prenatal and postpartum 28,000 group). Results Among 1164 infants assessed at 1 year of age (89.5% of 1300 pregnancies), there were no significant differences across groups in the mean (±SD) length-for-age z scores. Scores were as follows: placebo, -0.93±1.05; prenatal 4200, -1.11±1.12; prenatal 16,800, -0.97±0.97; prenatal 28,000, -1.06±1.07; and prenatal and postpartum 28,000, -0.94±1.00 (P=0.23 for a global test of differences across groups). Other anthropometric measures, birth outcomes

Full Text available with Trip Pro

2018 NEJM

84. Breast cancer diagnosed during pregnancy is associated with enrichment of non-silent mutations, mismatch repair deficiency signature and mucin mutations (PubMed)

Breast cancer diagnosed during pregnancy is associated with enrichment of non-silent mutations, mismatch repair deficiency signature and mucin mutations 30109263 2018 11 14 2374-4677 4 2018 NPJ breast cancer NPJ Breast Cancer Breast cancer diagnosed during pregnancy is associated with enrichment of non-silent mutations, mismatch repair deficiency signature and mucin mutations. 23 10.1038/s41523-018-0077-3 Breast cancer diagnosed during pregnancy (BCP) is a rare and highly challenging disease (...) . To investigate the impact of pregnancy on the biology of breast cancer, we conducted a comparative analysis of a cohort of BCP patients and non-pregnant control patients by integrating gene expression, copy number alterations and whole genome sequencing data. We showed that BCP exhibit unique molecular characteristics including an enrichment of non-silent mutations, a higher frequency of mutations in mucin gene family and an enrichment of mismatch repair deficiency mutational signature. This provides

Full Text available with Trip Pro

2018 NPJ breast cancer

85. How Do Home and Clinic Blood Pressure Readings Compare in Pregnancy?: A Systematic Review and Individual Patient Data Meta-Analysis (PubMed)

How Do Home and Clinic Blood Pressure Readings Compare in Pregnancy?: A Systematic Review and Individual Patient Data Meta-Analysis 30354754 2018 11 14 1524-4563 72 3 2018 Sep Hypertension (Dallas, Tex. : 1979) Hypertension How Do Home and Clinic Blood Pressure Readings Compare in Pregnancy? 686-694 10.1161/HYPERTENSIONAHA.118.10917 Hypertensive disorders during pregnancy result in substantial maternal morbidity and are a leading cause of maternal deaths worldwide. Self-monitoring of blood (...) pressure (BP) might improve the detection and management of hypertensive disorders of pregnancy, but few data are available, including regarding appropriate thresholds. This systematic review and individual patient data analysis aimed to assess the current evidence on differences between clinic and self-monitored BP through pregnancy. MEDLINE and 10 other electronic databases were searched for articles published up to and including July 2016 using a strategy designed to capture all the literature on self

Full Text available with Trip Pro

2018 Hypertension (Dallas, Tex. : 1979)

86. Continuation of Atypical Antipsychotic Medication During Early Pregnancy and the Risk of Gestational Diabetes

Continuation of Atypical Antipsychotic Medication During Early Pregnancy and the Risk of Gestational Diabetes 29730938 2018 06 07 1535-7228 175 6 2018 Jun 01 The American journal of psychiatry Am J Psychiatry Continuation of Atypical Antipsychotic Medication During Early Pregnancy and the Risk of Gestational Diabetes. 564-574 10.1176/appi.ajp.2018.17040393 Some atypical antipsychotics are associated with metabolic side effects, which are risk factors for gestational diabetes. The authors (...) examined the risk of developing gestational diabetes associated with the continuation of treatment with aripiprazole, ziprasidone, quetiapine, risperidone, and olanzapine during pregnancy compared with discontinuation of these antipsychotic drugs. Nondiabetic pregnant women who were linked to a live-born infant and enrolled in Medicaid (2000-2010) and who received one or more prescriptions dispensed for an antipsychotic drug during the 3 months before pregnancy were included in the analyses. Among

2018 EvidenceUpdates

87. Pregnancy

Pregnancy Top results for pregnancy - Trip Database or use your Google+ account Turning Research Into Practice My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing (...) the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for pregnancy The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines

2018 Trip Latest and Greatest

88. Low-Dose Aspirin Use During Pregnancy

Low-Dose Aspirin Use During Pregnancy ACOGCOMMITTEEOPINION Number 743 Committee on Obstetric Practice Society for Maternal–Fetal Medicine This Committee Opinion was developed by the Committee on Obstetric Practice in collaboration with committee member T. Flint Porter, MD, and the Society for Maternal–Fetal Medicine in collaboration with members Cynthia Gyamfi-Bannerman, MD, MS, and Tracy Manuck, MD. Low-Dose Aspirin Use During Pregnancy ABSTRACT: Low-dose aspirin has been used during pregnancy (...) , most commonly to prevent or delay the onset of preeclampsia. The American College of Obstetricians and Gynecologists issued the Hypertension in Pregnancy Task Force Reportrecommendingdailylow-doseaspirinbeginninginthelatefirsttrimesterforwomen with a history of early-onset preeclampsia and preterm delivery at less than 34 0/7 weeks of gestation, or for women with more than one prior pregnancy complicated by preeclampsia. The U.S. Preventive Services Task Force published a similar guideline

2018 American College of Obstetricians and Gynecologists

89. Air Travel During Pregnancy

Air Travel During Pregnancy INTERIM UPDATE ACOGCOMMITTEEOPINION Number 746 (Replaces Committee Opinion Number 443, October 2009) Committee on Obstetric Practice INTERIM UPDATE: This Committee Opinion is updated as highlighted to reflect a limited, focused change regarding the addition of a report on occupational exposure to ionizing radiation. Air Travel During Pregnancy ABSTRACT: In the absence of obstetric or medical complications, occasional air travel is safe for pregnant women. Pregnant (...) women can fly safely, observing the same precautions for air travel as the general population. Because severe air turbulence cannot be predicted and the subsequent risk for trauma is significant should this occur, pregnant women should be instructed to use their seat belts continuously while seated. Despite a lack of evidence associating lower extremity edema and venous thrombotic events with air travel during pregnancy, certain preventive measures can be used to minimize these risks, including use

2018 American College of Obstetricians and Gynecologists

90. Anticonvulsants and the risk of perinatal bleeding complications: A pregnancy cohort study

Anticonvulsants and the risk of perinatal bleeding complications: A pregnancy cohort study 29980637 2018 08 07 1526-632X 91 6 2018 Aug 07 Neurology Neurology Anticonvulsants and the risk of perinatal bleeding complications: A pregnancy cohort study. e533-e542 10.1212/WNL.0000000000005944 To examine the risk of postpartum hemorrhage (PPH) and neonatal bleeding complications associated with late-pregnancy exposure to anticonvulsant drugs (ACDs) that induce cytochrome P450 enzymes (ACDi) and alter (...) the metabolism of vitamin K compared to other ACDs. We used a population-based cohort study stemming from a nationwide sample of publicly insured pregnant women with a liveborn infant from the 2000 to 2010 Medicaid Analytic eXtract. ACDi (carbamazepine, phenobarbital, phenytoin, oxcarbazepine, topiramate) were compared to other ACDs dispensed during the last month of pregnancy. Relative risks (RRs) and 95% confidence intervals (CIs) of PPH and neonatal bleeding complications were estimated using generalized

2018 EvidenceUpdates

91. Association Between Vitamin D Supplementation During Pregnancy and Offspring Growth, Morbidity, and Mortality: A Systematic Review and Meta-analysis

Association Between Vitamin D Supplementation During Pregnancy and Offspring Growth, Morbidity, and Mortality: A Systematic Review and Meta-analysis 29813153 2018 07 05 2168-6211 172 7 2018 Jul 01 JAMA pediatrics JAMA Pediatr Association Between Vitamin D Supplementation During Pregnancy and Offspring Growth, Morbidity, and Mortality: A Systematic Review and Meta-analysis. 635-645 10.1001/jamapediatrics.2018.0302 Whether vitamin D supplementation during pregnancy is beneficial and safe (...) for offspring is unclear. To systematically review studies of the effects of vitamin D supplementation during pregnancy on offspring growth, morbidity, and mortality. Searches of Medline, Embase, and the Cochrane Database of Systematic Reviews were conducted up to October 31, 2017. Key search terms were vitamin D, pregnancy, randomized controlled trials, and offspring outcomes. Randomized clinical trials of vitamin D supplementation during pregnancy and offspring outcomes. Two authors independently

Full Text available with Trip Pro

2018 EvidenceUpdates

92. Recommendations on screening for asymptomatic bacteriuria in pregnancy (PubMed)

Recommendations on screening for asymptomatic bacteriuria in pregnancy 29986858 2018 07 17 1488-2329 190 27 2018 Jul 09 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Recommendations on screening for asymptomatic bacteriuria in pregnancy. E823-E830 10.1503/cmaj.171325 Moore Ainsley A Department of Family Medicine (Moore), McMaster University, Hamilton, Ont.; Public Health Agency of Canada (Doull, Courage, Jaramillo Garcia), Ottawa, Ont

Full Text available with Trip Pro

2018 EvidenceUpdates

93. Non-Invasive Markers (ALBI and APRI) Predict Pregnancy Outcomes in Women With Chronic Liver Disease

Non-Invasive Markers (ALBI and APRI) Predict Pregnancy Outcomes in Women With Chronic Liver Disease 29973705 2018 07 05 1572-0241 2018 Jul 05 The American journal of gastroenterology Am. J. Gastroenterol. Non-Invasive Markers (ALBI and APRI) Predict Pregnancy Outcomes in Women With Chronic Liver Disease. 10.1038/s41395-018-0181-x Rates of pregnancy in women with cirrhosis are increasing. Risk of hepatic decompensation during pregnancy, therefore, merits tailored obstetric and hepatology care (...) . Prognostic markers that determine pregnancy outcomes are lacking. Medical records of women who attended hepatology clinic at King's College Hospital with chronic liver disease (CLD) who became pregnant from 1983 to 2017 were reviewed. Information on demographics, clinical history, serology, and outcome of pregnancy was collected. In all, 165 pregnancies occurred in 100 women with CLD including 80 pregnancies in 48 women with cirrhosis. Median age of conception in cirrhotic and non-cirrhotic women were 26

2018 EvidenceUpdates

94. Darunavir boosted with cobicistat: avoid use in pregnancy due to risk of treatment failure and maternal-to-child transmission of HIV-1

Darunavir boosted with cobicistat: avoid use in pregnancy due to risk of treatment failure and maternal-to-child transmission of HIV-1 Darunavir boosted with cobicistat: avoid use in pregnancy due to risk of treatment failure and maternal-to-child transmission of HIV-1 - GOV.UK GOV.UK uses cookies to make the site simpler. Search Darunavir boosted with cobicistat: avoid use in pregnancy due to risk of treatment failure and maternal-to-child transmission of HIV-1 New pharmacokinetic data show (...) mean exposure of darunavir (brand name Prezista) boosted with cobicistat (available in combination in Rezolsta▼, Symtuza▼) to be lower during the second and third trimesters of pregnancy than during 6–12 weeks postpartum. Low darunavir exposure may be associated with an increased risk of treatment failure and an increased risk of HIV-1 transmission to the unborn child. Published 17 July 2018 From: Therapeutic area: , , , Contents Advice for healthcare professionals: pharmacokinetic data show low

2018 MHRA Drug Safety Update

95. Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial (PubMed)

Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial 30016328 2018 07 27 1549-1676 15 7 2018 Jul PLoS medicine PLoS Med. Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial. e1002606 10.1371/journal.pmed.1002606 Intermittent preventive treatment of malaria in pregnancy (...) (IPTp) with dihydroartemisinin-piperaquine (IPTp-DP) has been shown to reduce the burden of malaria during pregnancy compared to sulfadoxine-pyrimethamine (IPTp-SP). However, limited data exist on how IPTp regimens impact malaria risk during infancy. We conducted a double-blinded randomized controlled trial (RCT) to test the hypothesis that children born to mothers given IPTp-DP would have a lower incidence of malaria during infancy compared to children born to mothers who received IPTp-SP. We

Full Text available with Trip Pro

2018 EvidenceUpdates

96. [Influence of physical exercise during pregnancy on newborn weight: a randomized clinical trial]. (PubMed)

[Influence of physical exercise during pregnancy on newborn weight: a randomized clinical trial]. 29095006 2018 07 27 2018 10 23 1699-5198 34 4 2017 Jul 28 Nutricion hospitalaria Nutr Hosp [Influence of physical exercise during pregnancy on newborn weight: a randomized clinical trial]. 834-840 10.20960/nh.1095 Recent studies have proved that physical activity of the pregnant woman brings benefits not only for the mother but also for the fetus, given that it decreases the number of macrosomic (...) newborns and their negative consequences in both of them. To analyze in pregnant women the influence of a moderate physical activity program in the aquatic environment on the weight of the newborn. A randomized clinical trial with 140 healthy pregnant women, aged between 21 and 43 years, divided into two groups, study (GE, n = 70) and control (GC, n = 70). The women were attracted at 12 weeks of gestation in the first trimester ultrasound control carried out in the different obstetrical services

Full Text available with Trip Pro

2018 Nutricion hospitalaria

97. Metformin for women who are overweight or obese during pregnancy for improving maternal and infant outcomes. (PubMed)

Metformin for women who are overweight or obese during pregnancy for improving maternal and infant outcomes. BACKGROUND: There has been considerable interest in providing antenatal dietary and lifestyle advice for women with obesity or who are overweight during pregnancy, as a strategy to limit gestational weight gain and improve maternal and infant health. However, such antenatal interventions appear to have a modest effect on gestational weight gain and other clinical pregnancy and birth (...) outcomes and additional strategies are required.Metformin is an oral insulin-sensitising medication that acts to decrease blood glucose concentrations. Metformin is commonly used in the treatment of type 2 diabetes mellitus and polycystic ovarian syndrome, and is being used increasingly in the treatment of gestational diabetes, having been shown to result in decreased rates of caesarean birth and neonatal hypoglycaemia. Metformin may be an adjuvant therapy to current antenatal strategies in pregnant

2018 Cochrane

98. Novel therapies for diabetes mellitus in pregnancy. (PubMed)

Novel therapies for diabetes mellitus in pregnancy. Diabetes is a common complication of pregnancy, and the prevalence of all types of the disease is increasing worldwide. Diabetes in pregnancy is associated with short term and long term adverse effects for mother and child. The goal of treatment of diabetes in pregnancy is to minimize maternal and fetal adverse events related to hyperglycemia. Treatment options vary by type of diabetes, from a focus on lifestyle modifications in gestational (...) diabetes to continuous glucose monitoring and insulin pumps in pregestational diabetes. Nevertheless, given the commonality of hyperglycemia, considerable overlap exists in the treatment of different types of diabetes in pregnancy. Also, despite ongoing research on treatment of diabetes in pregnancy for decades, changes in the characteristics of the patient population have highlighted the limited effectiveness of different therapies. Specifically, despite the co-occurrence of obesity and diabetes

2018 BMJ

99. Platelet Counts during Pregnancy. (PubMed)

Platelet Counts during Pregnancy. BACKGROUND: Platelet counts of less than 150,000 per cubic millimeter during uncomplicated pregnancies are described as gestational thrombocytopenia if no alternative cause is identified. Platelet counts may be even lower in women with pregnancy-related complications. However, the occurrence and severity of thrombocytopenia throughout pregnancy are not defined. METHODS: We evaluated platelet counts throughout pregnancy in women who delivered at Oklahoma (...) University Medical Center between 2011 and 2014. These platelet counts were compared with those of nonpregnant women who were included in the National Health and Nutrition Examination Survey from 1999 through 2012. RESULTS: Among the 15,723 deliveries that occurred during the study period, 7351 women had sufficient data for our analyses. Of these women, 4568 had uncomplicated pregnancies, 2586 had pregnancy-related complications, and 197 had preexisting disorders associated with thrombocytopenia. Among

2018 NEJM

100. Cytomegalovirus Infection in One Fetus with Hypoplasia of the Pons in a Diamniotic-Dichorionic Twin Pregnancy (PubMed)

Cytomegalovirus Infection in One Fetus with Hypoplasia of the Pons in a Diamniotic-Dichorionic Twin Pregnancy 29984350 2018 07 09 2509-596X 4 2 2018 Apr Ultrasound international open Ultrasound Int Open Cytomegalovirus Infection in One Fetus with Hypoplasia of the Pons in a Diamniotic-Dichorionic Twin Pregnancy. E52-E53 10.1055/a-0591-5981 Altmann Reinhard R Department of Gynecology, Obstetrics and Gynecological Endocrinology, Kepler University Hospital, Johannes Kepler University Linz, Linz

Full Text available with Trip Pro

2018 Ultrasound international open