Latest & greatest articles for pregnancy

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This page lists the very latest high quality evidence on pregnancy and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for pregnancy

2021. Maternal smoking during pregnancy and evidence based intervention to promote cessation

Maternal smoking during pregnancy and evidence based intervention to promote cessation Maternal smoking during pregnancy and evidence based intervention to promote cessation Maternal smoking during pregnancy and evidence based intervention to promote cessation Mullen P D Authors' objectives The author's stated objective was to answer three questions: whether intervention to promote maternal smoking cessation during pregnancy is effective, what works best, and in which populations. However, only (...) of the interventions used in the included studies varied. Most had more than one of the following components: counselling, personal visits or sessions with various providers, phone contact, mailed materials, manuals, booklets, letters, pamphlets, video tapes, audio tapes, newsletters, goal setting, buddy support and clinic staff support. Participants included in the review The inclusion criteria were not explicit. However, by implication the eligible participants were pregnant smokers. Most of the included studies

1999 DARE.

2022. Expectant, medical, or surgical treatment of spontaneous abortion in first trimester of pregnancy: a pooled quantitative literature evaluation

Expectant, medical, or surgical treatment of spontaneous abortion in first trimester of pregnancy: a pooled quantitative literature evaluation Expectant, medical, or surgical treatment of spontaneous abortion in first trimester of pregnancy: a pooled quantitative literature evaluation Expectant, medical, or surgical treatment of spontaneous abortion in first trimester of pregnancy: a pooled quantitative literature evaluation Geyman J P, Oliver L M, Sullivan S D Authors' objectives To clarify (...) of pregnancy were eligible. Exclusion criteria were: patients with other types of abortion such as induced termination of pregnancy and missed abortion; spontaneous abortion beyond 13 weeks; patients with temperature higher than 100.4 degrees F, unstable blood-pressure and heart rate, uncontrolled vaginal bleeding, evidence of endometritis or pelvic inflammatory disease, or findings suggestive of ectopic pregnancy. Participants included women with: retained products of conception (15 to 50 mm

1999 DARE.

2023. Low-molecular-weight heparins in pregnancy

Low-molecular-weight heparins in pregnancy Low-molecular-weight heparins in pregnancy Low-molecular-weight heparins in pregnancy Ensom M H, Stephenson M D Authors' objectives To examine the effectiveness and safety of low molecular weight heparin (LMWH) in pregnancy. Searching Both the Cochrane Library (1998) and MEDLINE (Jan 1966-Jan 1999) were searched for English language articles using the keywords 'low-molecular-weight-heparin' and 'pregnancy'. The index and titles of key journals (...) U/kg single dose), enoxaparin (20 mg (2,000 IU) - 80 mg (8,000 U)/day), nadroparin (2,050 - 15,000 U/day), certoparin (3,000 U/day), PK10619 (60 - 80 mg/day), Org 10172 (2,000 - 3,400 U/day), and heparin calcium (1,000 U/day). Dose regimens featured fixed dosages, increasing dosages as pregnancy progressed, dosages based on body weight, and dosages titrated according to anti-Xa levels. Duration of therapy varied from a single dose to 476 days. Other comparison treatments included unfractionated

1999 DARE.

2024. Universal HIV screening of pregnant women in England: cost effectiveness analysis

per 10,000 pregnancies and screening cost 25. Major improvements were found when the discount rate was lowered to 3%, when the LYG were not discounted, and when there was a high lifetime cost of paediatric HIV care. Authors' conclusions Universal, voluntary antenatal screening for human immunodeficiency virus (HIV) was estimated to be a cost-effective intervention, with cost-saving potential in areas in which there is a high prevalence of HIV infection among pregnant women. In areas with lower (...) Universal HIV screening of pregnant women in England: cost effectiveness analysis Universal HIV screening of pregnant women in England: cost effectiveness analysis Universal HIV screening of pregnant women in England: cost effectiveness analysis Postma M J, Beck E J, Mandalia S, Sherr L, Walters M D, Houweling H, Jager J C Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods

1999 NHS Economic Evaluation Database.

2025. The value of sonography in early pregnancy for the detection of fetal abnormalities in an unselected population

financial implications of introducing an extra routine scan for all pregnant women in the first trimester. Source of funding None stated Bibliographic details Whitlow B J, Chatzipapas I K, Lazanakis M L, Kadir R A, Economides D L. The value of sonography in early pregnancy for the detection of fetal abnormalities in an unselected population. British Journal of Obstetrics and Gynaecology 1999; 106(9): 929-936 PubMedID Original Paper URL e=contents Other publications of related interest Vintzileos A M (...) The value of sonography in early pregnancy for the detection of fetal abnormalities in an unselected population The value of sonography in early pregnancy for the detection of fetal abnormalities in an unselected population The value of sonography in early pregnancy for the detection of fetal abnormalities in an unselected population Whitlow B J, Chatzipapas I K, Lazanakis M L, Kadir R A, Economides D L Record Status This is a critical abstract of an economic evaluation that meets the criteria

1999 NHS Economic Evaluation Database.

2026. Pharmacologic treatment of depression during pregnancy

Pharmacologic treatment of depression during pregnancy Pharmacologic treatment of depression during pregnancy Pharmacologic treatment of depression during pregnancy Wisner K L, Gelenberg A J, Leonard H, Zarin D, Frank E Authors' objectives To identify risk factors associated with treatment of major depression during pregnancy to help physicians develop treatment plans that optomise clinical care. Searching The authors searched MEDLINE and HealthSTAR from 1989 to 1999 using the search terms (...) 'antidepressant during pregnancy' and 'depression during pregnancy'. The authors also searched the bibliographies of retrieved articles and talked to other investigators for additional relevant studies. Study selection Study designs of evaluations included in the review Prospective studies in which maternal and infant health outcomes associated with antidepressant exposure were compared with those on teratogen-exposed controls. Specific interventions included in the review Tricyclic antidepressants

1999 DARE.

2027. Diabetes and pregnancy: preconception care, pregnancy outcomes, resource utilization and costs

Diabetes and pregnancy: preconception care, pregnancy outcomes, resource utilization and costs Diabetes and pregnancy: preconception care, pregnancy outcomes, resource utilization and costs Diabetes and pregnancy: preconception care, pregnancy outcomes, resource utilization and costs Herman W H, Janz N K, Becker M P, Charron-Prochownik D Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary (...) patient sample as that used in the effectiveness analysis Study sample Of 196 women with established diabetes who were identified, 154 (79%) were enrolled in the study. Of those enrolled in the study, 37% (n=57) received preconception care and only 44% of these (n=25) became pregnant, and all but one of them delivered by the study end. Of the 97 women who received prenatal care, 89 delivered. Because there were only 15 women with type 2 diabetes and they were all in the PN group, the authors limited

1999 NHS Economic Evaluation Database.

2028. Treatment of tubal pregnancy in the Netherlands: an economic comparison of systemic methotrexate administration and laparoscopic salpingostomy

Treatment of tubal pregnancy in the Netherlands: an economic comparison of systemic methotrexate administration and laparoscopic salpingostomy Treatment of tubal pregnancy in the Netherlands: an economic comparison of systemic methotrexate administration and laparoscopic salpingostomy Treatment of tubal pregnancy in the Netherlands: an economic comparison of systemic methotrexate administration and laparoscopic salpingostomy Mol B W, Hajenius P J, Engelsbel S, Ankum W M, Hemrika D J, Van der (...) Veen F, Bossuyt P M Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Systemic methotrexate administration for the treatment of patients with tubal pregnancy. Treatment was started immediately after laparoscopy and completed

1999 NHS Economic Evaluation Database.

2029. Domiciliary midwifery support in high-risk pregnancy incorporating telephonic fetal heart rate monitoring: a health technology randomized assessment

Domiciliary midwifery support in high-risk pregnancy incorporating telephonic fetal heart rate monitoring: a health technology randomized assessment Domiciliary midwifery support in high-risk pregnancy incorporating telephonic fetal heart rate monitoring: a health technology randomized assessment Domiciliary midwifery support in high-risk pregnancy incorporating telephonic fetal heart rate monitoring: a health technology randomized assessment Dawson A, Cohen D, Candelier C, Jones G, Sanders J (...) , Thompson A, Arnall C, Coles E Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of domiciliary care for pregnant women at risk of adverse outcomes. Enhanced domiciliary care comprised home visits from community midwives

1999 NHS Economic Evaluation Database.

2030. Membrane sweeping versus dinoprostone vaginal insert in the management of pregnancies beyond 41 weeks with an unfavourable cervix

Membrane sweeping versus dinoprostone vaginal insert in the management of pregnancies beyond 41 weeks with an unfavourable cervix Membrane sweeping versus dinoprostone vaginal insert in the management of pregnancies beyond 41 weeks with an unfavourable cervix Membrane sweeping versus dinoprostone vaginal insert in the management of pregnancies beyond 41 weeks with an unfavourable cervix Magann E F, Chauhan S P, McNamara M F, Bass J D, Estes C M, Morrison J C Record Status This is a critical (...) abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Membrane sweeping in the management of pregnancies beyond 42 weeks with an unfavourable cervix. Type of intervention Treatment and secondary prevention. Economic study type Cost-effectiveness analysis. Study population

1999 NHS Economic Evaluation Database.

2031. Cost of bacterial vaginosis in pregnancy: decision analysis and cost evaluation of a clinical study in Germany

. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Two strategies were compared for the screening and treatment of bacterial vaginosis during early pregnancy. The first strategy (A) was to screen all pregnant women and treat positive cases with clindamycin. The second strategy (B) was to screen all pregnant women and treat positive cases (...) of not screening pregnant women for bacterial vaginosis should be re-evaluated. Source of funding None stated. Bibliographic details Muller E, Berger K, Dennemark N, Oleen-Burkey M. Cost of bacterial vaginosis in pregnancy: decision analysis and cost evaluation of a clinical study in Germany. Journal of Reproductive and Infant Psychology 1999; 44(9): 807-814 Other publications of related interest Dennemark N, Meyer-Wilmes M, Schluter R. Screening and treatment of bacterial vaginosis in early second trimester

1999 NHS Economic Evaluation Database.

2032. Pregnancy rates after in-vitro fertilization in cases of tubal infertility with and without hydrosalpinx: a meta-analysis of published comparative studies

Pregnancy rates after in-vitro fertilization in cases of tubal infertility with and without hydrosalpinx: a meta-analysis of published comparative studies Pregnancy rates after in-vitro fertilization in cases of tubal infertility with and without hydrosalpinx: a meta-analysis of published comparative studies Pregnancy rates after in-vitro fertilization in cases of tubal infertility with and without hydrosalpinx: a meta-analysis of published comparative studies Camus E, Poncelet C, Goffinet F (...) , Wainer B, Merlet F, Nisand I, Philippe H J Authors' objectives To evaluate the differences in pregnancy rates after in vitro fertilisation (IVF) in tubal fertility with and without hydrosalpinx. Searching MEDLINE and the Cochrane Database of Systematic Reviews were searched. No search terms were provided. The reference list of the pertinent articles were also reviewed. Study selection Study designs of evaluations included in the review Any comparative study, where patients with hydrosalpinx were

1999 DARE.

2033. Treating allergic rhinitis in pregnancy: safety considerations

: no epidemiological studies in human pregnancy were identified. Authors' conclusions Immunotherapy and intranasal sodium chromoglycate and beclomethasone should be considered as first-line therapy for pregnant women with allergic rhinitis. First- and second-generation antihistamines have not been incriminated as human teratogens. First-generation antihistamines are favoured over second-generation counterparts on the basis of their longevity, leading to more conclusive evidence of safety. Oral, intranasal (...) Treating allergic rhinitis in pregnancy: safety considerations Treating allergic rhinitis in pregnancy: safety considerations Treating allergic rhinitis in pregnancy: safety considerations Mazzotta P, Loebstein R, Koren G Authors' objectives To determine the effects of allergic rhinitis therapy during pregnancy on foetal outcomes. Searching The following sources were searched for studies in English or French: MEDLINE (from 1966 to April 1998) using the keywords 'pregnancy', 'pregnancy

1999 DARE.

2034. Asthma in pregnancy

Asthma in pregnancy Asthma in pregnancy | CMAJ Main menu User menu Search Search for this keyword Search for this keyword Article Asthma in pregnancy Asthma is present in 4%-7% of pregnant women and is the respiratory disorder most frequently complicating pregnancy.[ , ] The course of asthma during pregnancy is variable, and asthma control may remain unchanged, or become worse or improve and return the to the prepregnancy state within 3 months after parturition.[ , ] Overall, asthma control (...) improves significantly in the last 4 weeks of pregnancy. Asthmatic pregnant women have been variably reported to have an increased risk of pregnancy-induced hypertension, pre-eclampsia, caesarian section, placenta previa and antepartum or postpartum hemorrhage.[ , – ] Poorly controlled asthma may affect maternal comfort and safety and pregnancy outcome for both mother and child. However, data from well-designed studies have shown that treated asthmatic women have fewer adverse infant and maternal

1999 CPG Infobase

2035. Is in-patient management of diastolic blood pressure between 90 and 100 mm Hg during pregnancy necessary? (Abstract)

Is in-patient management of diastolic blood pressure between 90 and 100 mm Hg during pregnancy necessary? A randomised controlled trial was performed at the Queen Elizabeth Hospital to compare the effects and acceptance of routine in-patient versus out-patient management of diastolic blood pressure between 90 and 100 mm Hg in pregnant women. There were no significant differences in the establishment of the diagnosis of hypertension, development of severe hypertension or proteinuric hypertension (...) groups did not differ in their levels of satisfaction of the overall management of blood pressure. Nevertheless, a greater proportion of women preferred to choose the same type of care among the out-patient group than among the in-patient group if they had hypertension in a future pregnancy (83.7% versus 51.2%; P<0.001). More women were dissatisfied about the number of admissions than on the frequency of out-patient care (40.5% versus 16.3%; P<0.001). We conclude that in-patient care, day care

1998 Hong Kong medical journal = Xianggang yi xue za zhi Controlled trial quality: uncertain

2036. Randomised trial of management of hypertensive pregnancies by Korotkoff phase IV or phase V. (Abstract)

Randomised trial of management of hypertensive pregnancies by Korotkoff phase IV or phase V. There is debate about whether diastolic blood pressure should be recorded as the fourth (muffling, K4) or fifth (disappearance, K5) Korotkoff sound in pregnancy. We compared maternal and fetal outcomes and the likelihood that episodes of severe hypertension would be recorded when hypertensive pregnancies were managed according to either K4 or K5.220 pregnant women with diastolic hypertension (K4 (...) for antihypertensive treatment, birthweight, fetal growth retardation, or perinatal mortality. There was no eclampsia or significant maternal morbidity in either group.A change from use of K4 to K5 would mean that one fewer case of severe diastolic hypertension would be recorded for every six hypertensive pregnancies, but all other episodes of severe hypertension would be recorded with similar frequency. Since the K4/K5 difference is smaller in hypertensive than in normotensive pregnant women and since K5

1998 Lancet Controlled trial quality: uncertain

2037. Randomised trial of effects of vitamin supplements on pregnancy outcomes and T cell counts in HIV-1-infected women in Tanzania. (Abstract)

Randomised trial of effects of vitamin supplements on pregnancy outcomes and T cell counts in HIV-1-infected women in Tanzania. In HIV-1-infected women, poor micronutrient status has been associated with faster progression of HIV-1 disease and adverse birth outcomes. We assessed the effects of vitamin A and multivitamins on birth outcomes in such women.In Tanzania, 1075 HIV-1-infected pregnant women at between 12 and 27 weeks' gestation received placebo (n=267), vitamin A (n=269), multivitamins (...) the risk of low birthweight (<2500 g) by 44% (0.56 [0.38-0.82] p=0.003), severe preterm birth (<34 weeks of gestation) by 39% (0.61 [0.38-0.96] p=0.03), and small size for gestational age at birth by 43% (0.57 [0.39-0.82] p=0.002). Vitamin A supplementation had no significant effect on these variables. Multivitamins, but not vitamin A, resulted in a significant increase in CD4, CD8, and CD3 counts.Multivitamin supplementation is a low-cost way of substantially decreasing adverse pregnancy outcomes

1998 Lancet Controlled trial quality: predicted high

2038. Randomised trial of nitric oxide donor versus prostaglandin for cervical ripening before first-trimester termination of pregnancy. (Abstract)

Randomised trial of nitric oxide donor versus prostaglandin for cervical ripening before first-trimester termination of pregnancy. Vaginal administration of the nitric oxide donor isosorbide mononitrate can induce effective ripening of the human cervix. We investigated whether this drug is associated with fewer side-effects than prostaglandins when used to ripen the cervix before first-trimester surgical termination of pregnancy, and assessed whether the extent of cervical ripening it induces (...) with isosorbide mononitrate to ripen the cervix before first-trimester termination of pregnancy is associated with fewer side-effects than gemeprost treatment and adequately decreases cervical resistance. Isosorbide mononitrate could be used as an alternative to gemeprost for this indication.

1998 Lancet Controlled trial quality: uncertain

2039. Routine ultrasound in pregnancy

Routine ultrasound in pregnancy Routine ultrasound in pregnancy Routine ultrasound in pregnancy Hagenfeldt K, Alton Lundberg V, Axelsson O, Blennow M, Boj F, Bygdemann M, et al Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation Hagenfeldt K, Alton Lundberg V, Axelsson O, Blennow M, Boj F, Bygdemann M, et al. Routine ultrasound in pregnancy (...) . Stockholm: Swedish Council on Technology Assessment in Health Care (SBU) 1998: 263 Authors' objectives The purpose of this assessment is to investigate the medical benefits of routine ultrasound during pregnancy and the risks to the mother and child, including the short-term and long-term physical risks and the psychological impact. The assessment also includes an analysis of economic costs. The Swedish government commissioned SBU to conduct this assessment. Authors' conclusions There is no scientific

1998 Health Technology Assessment (HTA) Database.

2040. Diagnostic efficiency of home pregnancy test kits: a meta-analysis

', 'pregnancy test' and 'home test'. References cited in articles and those listed in the bibliographies of standard obstetric texts were also retrieved. Attempts were made to obtain information from the manufacturers of HPT kits, but none was obtained. Study selection Study designs of evaluations included in the review The studies were required to included appropriate (non-pregnant) controls and to report on a sample size greater than 20. Review articles were excluded. Specific interventions included (...) Diagnostic efficiency of home pregnancy test kits: a meta-analysis Diagnostic efficiency of home pregnancy test kits: a meta-analysis Diagnostic efficiency of home pregnancy test kits: a meta-analysis Bastian L A, Nanda K, Hasselblad V, Simel D L Authors' objectives To assess the diagnostic efficacy of home pregnancy test (HPT) kits. Searching MEDLINE and HealthSTAR were searched for English language articles published between 1966 and 1996 using the keywords 'pregnancy', 'diagnosis

1998 DARE.