Latest & greatest articles for paroxetine

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Top results for paroxetine

1. Paroxetine

Paroxetine Top results for paroxetine - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2 (...) ) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for paroxetine The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms

2018 Trip Latest and Greatest

2. Pharmacological interventions: Are sertraline, paroxetine and duloxetine the most effective antidepressants for use in depressed adults over 60?years?

Pharmacological interventions: Are sertraline, paroxetine and duloxetine the most effective antidepressants for use in depressed adults over 60?years? Are sertraline, paroxetine and duloxetine the most effective antidepressants for use in depressed adults over 60 years? | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies (...) , please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Are sertraline, paroxetine and duloxetine the most effective antidepressants for use in depressed adults over 60

2016 Evidence-Based Mental Health

3. Randomised controlled trial: Both paroxetine and imipramine appear to be ineffective in adolescents with major depression, furthermore doubts have risen about their safety

Randomised controlled trial: Both paroxetine and imipramine appear to be ineffective in adolescents with major depression, furthermore doubts have risen about their safety Both paroxetine and imipramine appear to be ineffective in adolescents with major depression, furthermore doubts have risen about their safety | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time (...) . To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Both paroxetine and imipramine appear to be ineffective in adolescents

2016 Evidence-Based Medicine (Requires free registration)

4. Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence. (PubMed)

Restoring Study 329: efficacy and harms of paroxetine and imipramine in treatment of major depression in adolescence. To reanalyse SmithKline Beecham's Study 329 (published by Keller and colleagues in 2001), the primary objective of which was to compare the efficacy and safety of paroxetine and imipramine with placebo in the treatment of adolescents with unipolar major depression. The reanalysis under the restoring invisible and abandoned trials (RIAT) initiative was done to see whether access (...) treatment with paroxetine (20-40 mg), imipramine (200-300 mg), or placebo.The prespecified primary efficacy variables were change from baseline to the end of the eight week acute treatment phase in total Hamilton depression scale (HAM-D) score and the proportion of responders (HAM-D score ≤8 or ≥50% reduction in baseline HAM-D) at acute endpoint. Prespecified secondary outcomes were changes from baseline to endpoint in depression items in K-SADS-L, clinical global impression, autonomous functioning

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2015 BMJ

5. Paroxetine versus other anti-depressive agents for depression. (PubMed)

Paroxetine versus other anti-depressive agents for depression. Paroxetine is the most potent inhibitor of the reuptake of serotonin of all selective serotonin reuptake inhibitors (SSRIs) and has been studied in many randomised controlled trials (RCTs). However, these comparative studies provided contrasting findings and systematic reviews of RCTs have always considered the SSRIs as a group, and evidence applicable to this group of drugs might not be applicable to paroxetine alone. The present (...) systematic review assessed the efficacy and tolerability profile of paroxetine in comparison with tricyclics (TCAs), SSRIs and newer or non-conventional agents.1. To determine the efficacy of paroxetine in comparison with other anti-depressive agents in alleviating the acute symptoms of Major Depressive Disorder.2. To review acceptability of treatment with paroxetine in comparison with other anti-depressive agents.3. To investigate the adverse effects of paroxetine in comparison with other anti

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2014 Cochrane

6. Paroxetine

Paroxetine USE OF PAROXETINE IN PREGNANCY 0344 892 0909 USE OF PAROXETINE IN PREGNANCY (Date of issue: January 2017 , Version: 2.3 ) This is a UKTIS monograph for use by health care professionals. For case-specific advice please contact UKTIS on 0344 892 0909. To report an exposure please download and complete a . Please encourage all women to complete an . A corresponding patient information leaflet on is available at . Summary Paroxetine is a selective serotonin reuptake inhibitor (SSRI) used (...) in the treatment of depression, obsessive-compulsive disorder, post-traumatic stress disorder, anxiety disorders (generalised or social) and panic disorder with or without agoraphobia. Data on the risk of congenital malformations following paroxetine use in early pregnancy are conflicting; the majority of individual studies have demonstrated no statistically significant increase in the overall risk of any malformation or of cardiac malformations specifically. However, some, but not all, meta-analyses have

2014 UK Teratology Information Service

7. Efficacy and tolerability of mirtazapine versus paroxetine in the treatment of major depressive disorder

Efficacy and tolerability of mirtazapine versus paroxetine in the treatment of major depressive disorder Efficacy and tolerability of mirtazapine versus paroxetine in the treatment of major depressive disorder Efficacy and tolerability of mirtazapine versus paroxetine in the treatment of major depressive disorder Gonzalez Rodriguez A, Gasto Ferrer C, Navarro Odriozola V CRD summary The authors concluded that mirtazapine was effective earlier, but at six to eight weeks, paroxetine was equally (...) effective for the treatment of major depressive disorder. There were some methodological limitations, and no validity assessment, leaving the reliability of the conclusions uncertain. Authors' objectives To compare the efficacy and tolerability of paroxetine with those of mirtazapine for the treatment of major depressive disorder. Searching PubMed and PsycINFO were searched for articles from 1980 to June 2011; search terms were reported. It appears that published systematic reviews were checked

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2013 DARE.

8. Fluoxetine and sertraline may be associated with lower risk of suicide death than paroxetine in adults with depression

Fluoxetine and sertraline may be associated with lower risk of suicide death than paroxetine in adults with depression Fluoxetine and sertraline may be associated with lower risk of suicide death than paroxetine in adults with depression | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Fluoxetine and sertraline may be associated with lower risk of suicide death than paroxetine in adults with depression Article Text Aetiology Fluoxetine

2012 Evidence-Based Mental Health

9. Efficacy and tolerability of mirtazapine in treating major depressive disorder with anxiety symptoms: an 8-week open-label randomised paroxetine-controlled trial (PubMed)

Efficacy and tolerability of mirtazapine in treating major depressive disorder with anxiety symptoms: an 8-week open-label randomised paroxetine-controlled trial Prominent anxiety symptoms are related to poor clinical course and outcome in major depressive disorder (MDD). The aim of this randomised, open-label, controlled study is to compare the efficacy and tolerability of mirtazapine in the form of orally disintegrating tablets against paroxetine in treating MDD patients with anxiety (...) symptoms.A total of 60 MDD patients with a score above 18 on the Hamilton Anxiety Rating Scale (HARS) were randomly assigned to 8 weeks of fixed dosing treatment with mirtazapine (15-30 mg/day) and paroxetine (10-20 mg/day). Efficacy was primarily assessed with the HARS and with the 17-item Hamilton Depression Rating Scale (HDRS) at weeks 1, 2, 4 and 8 after treatment. Tolerability was assessed from adverse events.The generalised estimating equations (GEE) models showed that the rates of improvement

2011 EvidenceUpdates

10. Selective serotonin reuptake inhibitor exposure during early pregnancy and the risk of fetal major malformations: focus on paroxetine

Selective serotonin reuptake inhibitor exposure during early pregnancy and the risk of fetal major malformations: focus on paroxetine Selective serotonin reuptake inhibitor exposure during early pregnancy and the risk of fetal major malformations: focus on paroxetine Selective serotonin reuptake inhibitor exposure during early pregnancy and the risk of fetal major malformations: focus on paroxetine Gentile S, Bellantuono C CRD summary This review concluded that the data were too inconsistent (...) to confirm or exclude the risk of major foetal malformations after exposure to paroxetine during early pregnancy. The review had major flaws in terms of an unreported review process and absence of study quality assessment. The extent to which the conclusion is a reliable assessment of the evidence base is unclear. Authors' objectives To assess the effect of prenatally administered paroxetine on the prevalence of major foetal malformations. Searching MEDLINE, TOXNET, EMBASE, and the Cochrane Library were

2009 DARE.

11. Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder

Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password (...) For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder Article Text Therapeutics Escitalopram 10 mg daily is more effective than

2008 Evidence-Based Mental Health

12. Effectiveness of paroxetine in the treatment of acute major depression in adults: a systematic re-examination of published and unpublished data from randomized trials (PubMed)

Effectiveness of paroxetine in the treatment of acute major depression in adults: a systematic re-examination of published and unpublished data from randomized trials Concern has been raised about the efficacy of antidepressant therapy for major depression in adults. We undertook a systematic review of published and unpublished clinical trial data to determine the effectiveness and acceptability of paroxetine.We searched the Cochrane Collaboration Depression, Anxiety and Neurosis Controlled (...) Trials Register, the Cochrane Central Register of Controlled Trials, the GlaxoSmithKline Clinical Trial Register, MEDLINE and EMBASE up to December 2006. Published and unpublished randomized trials comparing paroxetine with placebo in adults with major depression were eligible for inclusion. We selected the proportion of patients who left a study early for any reason as the primary outcome measure because it represents a hard measure of treatment effectiveness and acceptability.We included in our

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2008 EvidenceUpdates

13. Does paroxetine cause cardiac malformations?

Does paroxetine cause cardiac malformations? Does paroxetine cause cardiac malformations? Does paroxetine cause cardiac malformations? O'Brien L, Einarson TR, Sarkar M, Einarson A, Koren G CRD summary This generally well-conducted review of non-randomised studies concluded that first trimester exposure to paroxetine did not appear to be associated with increased rates of cardiac malformations. This conclusion reflects the results of this review of reasonable quality studies that included (...) a large number of women and is likely to be reliable. Authors' objectives To determine whether first trimester exposure to paroxetine is associated with an increased rate of cardiac defects. Searching MEDLINE, EMBASE, REPROTOX, Scopus and Biological Abstracts were searched from January 1985 to November 2007. No language restrictions were reported. Search terms were reported. References of retrieved articles, proceedings of professional societies in relevant fields and Internet sites were searched

2008 DARE.

14. Effectiveness of paroxetine in the treatment of acute major depression in adults: a systematic re-examination of published and unpublished data from randomized trials

Effectiveness of paroxetine in the treatment of acute major depression in adults: a systematic re-examination of published and unpublished data from randomized trials Effectiveness of paroxetine in the treatment of acute major depression in adults: a systematic re-examination of published and unpublished data from randomized trials Effectiveness of paroxetine in the treatment of acute major depression in adults: a systematic re-examination of published and unpublished data from randomized (...) trials Barbui C, Furukawa T A, Cipriani A CRD summary This review evaluated the effectiveness and acceptability of paroxetine in major depression, concluding paroxetine was not superior to placebo in terms of the proportion of study participants discontinuing treatment for any reason. Paoxetine had a modest effect in terms of depression measures. The conclusions appeared broadly appropriate, although they possibly overemphasised the less meaningful efficacy outcome of treatment withdrawal. Authors

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2008 DARE.

15. Review: paroxetine and placebo do not differ for treatment discontinuation in major depression

Review: paroxetine and placebo do not differ for treatment discontinuation in major depression Review: paroxetine and placebo do not differ for treatment discontinuation in major depression | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Review: paroxetine and placebo do not differ for treatment discontinuation in major depression Article Text Therapeutics Review: paroxetine and placebo do not differ for treatment discontinuation

2008 Evidence-Based Medicine (Requires free registration)

16. Maintenance treatment with paroxetine, but not psychotherapy, prevented recurrent major depression in older people

Maintenance treatment with paroxetine, but not psychotherapy, prevented recurrent major depression in older people Maintenance treatment with paroxetine, but not psychotherapy, prevented recurrent major depression in older people | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Maintenance treatment with paroxetine, but not psychotherapy, prevented recurrent major depression in older people Article Text Therapeutics Maintenance treatment

2007 Evidence-Based Medicine (Requires free registration)

17. Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder. (PubMed)

Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder. 17459976 2007 05 22 2007 04 26 1362-0347 10 2 2007 May Evidence-based mental health Evid Based Ment Health Escitalopram 10 mg daily is more effective than paroxetine and placebo for generalised anxiety disorder. 45 Gale Christopher C Department of Psychological Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand. eng Comment Journal Article England Evid Based Ment

2007 Evidence-Based Mental Health

18. Paroxetine versus placebo and other agents for depressive disorders: a systematic review and meta-analysis

Paroxetine versus placebo and other agents for depressive disorders: a systematic review and meta-analysis Paroxetine versus placebo and other agents for depressive disorders: a systematic review and meta-analysis Paroxetine versus placebo and other agents for depressive disorders: a systematic review and meta-analysis Katzman M A, Tricco A C, McIntosh D, Filteau M J, Bleau P, Chokka P R, Kjernisted K D, Mok H, Pham B CRD summary This review concluded that there were no consistent and valid (...) differences to suggest that multiple modes of action improved clinical outcomes between paroxetine and other antidepressants for depressive disorders. This was a generally well-conducted review. The authors' conclusions appear to be reliable. Authors' objectives To examine the efficacy of paroxetine versus placebo and other antidepressants in the treatment of depressive disorders. Searching MEDLINE, EMBASE, CINAHL, all Evidence-Based Medicine Reviews, HealthSTAR, BIOSIS Previews and PsycINFO were searched

2007 DARE.

19. St John’s wort is at least as effective as paroxetine in reducing severity of depression and is better tolerated

St John’s wort is at least as effective as paroxetine in reducing severity of depression and is better tolerated St John’s wort is at least as effective as paroxetine in reducing severity of depression and is better tolerated | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username (...) and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here St John’s wort is at least as effective as paroxetine in reducing severity of depression and is better tolerated Article Text Therapeutics St John’s wort is at least

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2006 Evidence-Based Mental Health

20. Paroxetine improves social anxiety disorder in children and adolescents

Paroxetine improves social anxiety disorder in children and adolescents Paroxetine improves social anxiety disorder in children and adolescents | Evidence-Based Mental Health We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username (...) * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Paroxetine improves social anxiety disorder in children and adolescents Article Text Therapeutics Paroxetine improves social anxiety disorder in children and adolescents Free Katharina Manassis , MD, FRCP(C) Statistics from Altmetric.com Wagner KD

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2006 Evidence-Based Mental Health