Latest & greatest articles for palliative care

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on palliative care or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on palliative care and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for palliative care

61. Australian Model of Rural Palliative Care: Clinical Evidence

Australian Model of Rural Palliative Care: Clinical Evidence Australian Model of Rural Palliative Care: Clinical Evidence | CADTH.ca Find the information you need Australian Model of Rural Palliative Care: Clinical Evidence Australian Model of Rural Palliative Care: Clinical Evidence Last updated: September 5, 2018 Project Number: RB1258-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What is the clinical evidence regarding (...) the use of the Australian Model of Rural Palliative Care for adult patients in rural, remote or northern settings? What are the evidence-based guidelines regarding the use of the Australian Model of Rural Palliative Care for adult patients in rural, remote or northern settings? Key Message No relevant literature was identified regarding the Australian Model of Rural Palliative Care for adult patients in rural, remote, or northern settings. Files Rapid Response Summary of Abstracts Published

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

62. Medical Cannabis Use in Palliative Care: Clinical Effectiveness and Guidelines

Medical Cannabis Use in Palliative Care: Clinical Effectiveness and Guidelines Medical Cannabis Use in Palliative Care: Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Medical Cannabis Use in Palliative Care: Clinical Effectiveness and Guidelines Medical Cannabis Use in Palliative Care: Clinical Effectiveness and Guidelines Last updated: September 10, 2018 Project Number: RB1257-000 Product Line: Research Type: Drug Report Type: Summary of Abstracts Result type (...) : Report Question What is the clinical effectiveness of medical cannabis products for symptom control in adult palliative care patients? What are the evidence-based guidelines regarding medical cannabis products for symptom control in adult palliative care patients? Key Message Two systematic reviews (one with a meta-analysis), one non-randomized study, and two evidence-based guidelines were identified regarding medical cannabis products for symptom control in adult palliative care patients. Files

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

63. The Canadian Hospice Palliative Care Model for Palliative Care: Clinical Evidence and Guidelines

The Canadian Hospice Palliative Care Model for Palliative Care: Clinical Evidence and Guidelines The Canadian Hospice Palliative Care Model for Palliative Care: Clinical Evidence and Guidelines | CADTH.ca Find the information you need The Canadian Hospice Palliative Care Model for Palliative Care: Clinical Evidence and Guidelines The Canadian Hospice Palliative Care Model for Palliative Care: Clinical Evidence and Guidelines Last updated: November 5, 2018 Project Number: RB1276-000 Product Line (...) : Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What is the clinical evidence supporting the use of the Canadian Hospice Palliative Care Model for adults requiring palliative care in any setting? What are the evidence-based guidelines associated with the use of the Canadian Hospice Palliative Care Model for adults requiring palliative care in any setting? Key Message No relevant literature regarding the Canadian Hospice Palliative Care Model for adults

2018 Canadian Agency for Drugs and Technologies in Health - Rapid Review

64. In patients receiving palliative care, risperidone or haloperidol increased delirium symptoms vs placebo. (PubMed)

In patients receiving palliative care, risperidone or haloperidol increased delirium symptoms vs placebo. 28320006 2017 12 08 2018 12 02 1539-3704 166 6 2017 03 21 Annals of internal medicine Ann. Intern. Med. In patients receiving palliative care, risperidone or haloperidol increased delirium symptoms vs placebo. JC32 10.7326/ACPJC-2017-166-6-032 Lee Justin J Holbrook Anne A McMaster UniversityHamilton, Ontario, Canada. eng Journal Article Comment United States Ann Intern Med 0372351 0003-4819 (...) 0 Antipsychotic Agents J6292F8L3D Haloperidol L6UH7ZF8HC Risperidone AIM IM JAMA Intern Med. 2017 Jan 1;177(1):34-42 27918778 Antipsychotic Agents Delirium Double-Blind Method Haloperidol Humans Palliative Care Risperidone 2017 3 21 6 0 2017 3 21 6 0 2017 12 9 6 0 ppublish 28320006 2612421 10.7326/ACPJC-2017-166-6-032

2017 Annals of Internal Medicine Controlled trial quality: uncertain

65. Effect of Inpatient Palliative Care During Hematopoietic Stem-Cell Transplant on Psychological Distress 6 Months After Transplant: Results of a Randomized Clinical Trial

Effect of Inpatient Palliative Care During Hematopoietic Stem-Cell Transplant on Psychological Distress 6 Months After Transplant: Results of a Randomized Clinical Trial Purpose Inpatient palliative care integrated with transplant care improves patients' quality of life (QOL) and symptom burden during hematopoietic stem-cell transplant (HCT). We assessed patients' mood, post-traumatic stress disorder (PTSD) symptoms, and QOL 6 months post-transplant. Methods We randomly assigned 160 patients (...) with hematologic malignancies who underwent autologous or allogeneic HCT to inpatient palliative care integrated with transplant care (n = 81) or transplant care alone (n = 79). At baseline and 6 months post-transplant, we assessed mood, PTSD symptoms, and QOL with the Hospital Anxiety and Depression Scale and Patient Health Questionnaire, PTSD checklist, and Functional Assessment of Cancer Therapy-Bone Marrow Transplant. To assess symptom burden during HCT, we used the Edmonton Symptom Assessment Scale. We

2017 EvidenceUpdates

66. Palliative Care in Heart Failure: Rationale, Evidence, and Future Priorities

Palliative Care in Heart Failure: Rationale, Evidence, and Future Priorities Patients with heart failure (HF) and their families experience stress and suffering from a variety of sources over the course of the HF experience. Palliative care is an interdisciplinary service and an overall approach to care that improves quality of life and alleviates suffering for those living with serious illness, regardless of prognosis. In this review, we synthesize the evidence from randomized clinical trials (...) of palliative care interventions in HF. While the evidence base for palliative care in HF is promising, it is still in its infancy and requires additional high-quality, methodologically sound studies to clearly elucidate the role of palliative care for patients and families living with the burdens of HF. Yet, an increase in attention to primary palliative care (e.g., basic physical and emotional symptom management, advance care planning), provided by primary care and cardiology clinicians, may be a vehicle

2017 EvidenceUpdates

67. Integrated Outpatient Palliative Care in Oncology

Integrated Outpatient Palliative Care in Oncology Management Briefs eBrief-no134 -- Enter search terms Button to search HSRD ® Inside VA Budget and Performance Inside the News Room National Observances Special Events » » » » » Management Briefs eBrief-no134 -- Health Services Research & Development Management eBrief no. 134 » Issue 134 November 2017 The report is a product of the VA/HSR&D Evidence Synthesis Program. Evidence Report: Integrated Outpatient Palliative Care in Oncology More than (...) 500,000 Americans, including 40,000 Veterans, are diagnosed with advanced cancer annually in the United States. Often provided concurrently with oncology care, palliative care improves quality of life by managing patients' physical symptoms, as well as psychosocial and spiritual distress. Palliative care occurs across a continuum, ideally beginning at the time when a serious illness has been diagnosed and continuing until the end of life. Integration of palliative care and oncology care is now

2017 Veterans Affairs - R&D

68. One Emergency Medicine Resident. One Month of Palliative Care. Ten lessons.

One Emergency Medicine Resident. One Month of Palliative Care. Ten lessons. One Emergency Medicine Resident. Ten Lessons in Palliative Care. One Emergency Medicine Resident. One Month of Palliative Care. Ten lessons. In by Brittany Ellis October 17, 2017 As emergency medicine residents, we work side-by-side with a wealth of specialities to gain clinical and diagnostic skills and to learn what happens to our patients when they leave the ED. We strive to distill the information we need to make (...) ourselves better clinicians and improve the transition of patients from the ED to inpatient teams. However, only rarely do we get to see where our patients came from, what happened prior to their ED arrival, and where they will go when they leave the hospital. Over the past month I have done just that as a senior resident on community and in-patient palliative care teams. It was more challenging and rewarding than I had ever imagined. Below I share my top ten lessons from these experiences that I hope

2017 CandiEM

69. Guidelines on Management of Pain in Cancer and/or Palliative Care

Guidelines on Management of Pain in Cancer and/or Palliative Care | Cancer Care Ontario Google Tag Manager You are using an outdated browser. We suggest you update your browser for a better experience. for update. Browse Guidelines Browse Pathway Maps Sort by You are here / / Guidelines on Management of Pain in Cancer and/or Palliative Care Guidelines & Advice Guidelines on Management of Pain in Cancer and/or Palliative Care ID: ES 18-4 Sep 2017 Type of Content: Guidelines & Advice, Evidence (...) as a source of information for the Ontario Palliative Care Network (OPCN). Patient Population Patients with cancer or other diseases requiring palliative care. Intended Guideline Users The intended users of this evidence summary are staff of the Patient Reported Outcomes and Symptom Management Program of CCO and staff of the Ontario Palliative Care Network. This evidence summary may also be of interest to physicians, nurses, caregivers, and patients dealing with cancer or palliative care symptom

2017 Cancer Care Ontario

70. Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial. (PubMed)

Effect of Lorazepam With Haloperidol vs Haloperidol Alone on Agitated Delirium in Patients With Advanced Cancer Receiving Palliative Care: A Randomized Clinical Trial. The use of benzodiazepines to control agitation in delirium in the last days of life is controversial.To compare the effect of lorazepam vs placebo as an adjuvant to haloperidol for persistent agitation in patients with delirium in the setting of advanced cancer.Single-center, double-blind, parallel-group, randomized clinical (...) trial conducted at an acute palliative care unit at MD Anderson Cancer Center, Texas, enrolling 93 patients with advanced cancer and agitated delirium despite scheduled haloperidol from February 11, 2014, to June 30, 2016, with data collection completed in October 2016.Lorazepam (3 mg) intravenously (n = 47) or placebo (n = 43) in addition to haloperidol (2 mg) intravenously upon the onset of an agitation episode.The primary outcome was change in Richmond Agitation-Sedation Scale (RASS) score (range

Full Text available with Trip Pro

2017 JAMA Controlled trial quality: predicted high

71. Palliative care and management of troublesome symptoms for people with chronic obstructive pulmonary disease. (PubMed)

Palliative care and management of troublesome symptoms for people with chronic obstructive pulmonary disease. People with advanced chronic obstructive pulmonary disease (COPD) have distressing physical and psychological symptoms, often have limited understanding of their disease, and infrequently discuss end-of-life issues in routine clinical care. These are strong indicators for expert multidisciplinary palliative care, which incorporates assessment and management of symptoms and concerns (...) , patient and caregiver education, and sensitive communication to elicit preferences for care towards the end of life. The unpredictable course of COPD and the difficulty of predicting survival are barriers to timely referral and receipt of palliative care. Early integration of palliative care with respiratory, primary care, and rehabilitation services, with referral on the basis of the complexity of symptoms and concerns, rather than prognosis, can improve patient and caregiver outcomes. Models

Full Text available with Trip Pro

2017 Lancet

72. European Association for Neuro-Oncology (EANO) guidelines for palliative care in adults with glioma

European Association for Neuro-Oncology (EANO) guidelines for palliative care in adults with glioma Patients with glioma present with complex palliative care needs throughout their disease trajectory. The life-limiting nature of gliomas and the presence of specific symptoms related to neurological deterioration necessitate an appropriate and early palliative care approach. The multidisciplinary palliative care task force of the European Association of Neuro-Oncology did a systematic review (...) of the available scientific literature to formulate the best possible evidence-based recommendations for the palliative care of adult patients with glioma, with the aim to reduce symptom burden and improve the quality of life of patients and their caregivers, particularly in the end-of-life phase. When recommendations could not be made because of the scarcity of evidence, the task force either used evidence from studies of patients with systemic cancer or formulated expert opinion. Areas of palliative care

Full Text available with Trip Pro

2017 EvidenceUpdates

73. Prevalence of burnout in health professionals working in palliative care: a systematic review. (PubMed)

Prevalence of burnout in health professionals working in palliative care: a systematic review. More than ever, the current increasing need for palliative care leads to health professionals providing this type of care which further leads to multiple challenges, and stressful and demanding situations. The multiple challenges of working in palliative care put health professionals working in this context at the risk of burnout.To examine the evidence on the prevalence of burnout among health (...) professionals working in palliative care.The current review included studies that encompass qualified health professionals working in palliative care, caring for patients 18 years of age or older.The current review considered studies reporting on the point prevalence of burnout, measured by a burnout scale, such as, but not limited to, the Maslach Burnout Inventory, Burnout Measure and Copenhagen Burnout Inventory.The current review considered studies conducted in the context of specialist palliative care

2017 JBI database of systematic reviews and implementation reports

74. Palliative Care Development in Africa: Lessons From Uganda and Kenya (PubMed)

Palliative Care Development in Africa: Lessons From Uganda and Kenya Despite increased access to palliative care in Africa, there remains substantial unmet need. We examined the impact of approaches to promoting the development of palliative care in two African countries, Uganda and Kenya, and considered how these and other strategies could be applied more broadly.This study reviews published data on development approaches to palliative care in Uganda and Kenya across five domains: education (...) and training, access to opioids, public and professional attitudes, integration into national health systems, and research. These countries were chosen because they are African leaders in palliative care, in which successful approaches to palliative care development have been used.Both countries have implemented strategies across all five domains to develop palliative care. In both countries, successes in these endeavors seem to be related to efforts to integrate palliative care into the national health

Full Text available with Trip Pro

2017 Journal of global oncology

75. Raise the Bar, Not the Threshold Value: Meeting Patient Preferences for Palliative and End-of-Life Care (PubMed)

Raise the Bar, Not the Threshold Value: Meeting Patient Preferences for Palliative and End-of-Life Care 29623615 2018 11 14 2509-4254 2 2 2018 Jun PharmacoEconomics - open Pharmacoecon Open Raise the Bar, Not the Threshold Value: Meeting Patient Preferences for Palliative and End-of-Life Care. 93-95 10.1007/s41669-017-0039-y McCaffrey Nikki N http://orcid.org/0000-0003-3684-3723 Deakin Health Economics, Deakin University, 221 Burwood Highway, Burwood, VIC, 3125, Australia. nikki.mccaffrey (...) 15904746 Patient. 2017 Jun;10(3):353-365 28271387 Palliat Med. 2008 Oct;22(7):787-95 18755830 Support Care Cancer. 2015 Jan;23(1):103-10 24996829 Palliat Med. 2017 Apr;31(4):291-292 28281407 PLoS One. 2015 Mar 09;10(3):e0115544 25751629 J Clin Oncol. 2012 Oct 10;30(29):3611-7 22965960 JAMA. 2000 Nov 15;284(19):2476-82 11074777 J Pain Symptom Manage. 2016 Aug;52(2):318-328.e5 27216362 BMC Palliat Care. 2013 Feb 15;12:7 23414145 Soc Sci Med. 2015 Jan;124:48-56 25461861 Int J Health Policy Manag. 2016 Jun

Full Text available with Trip Pro

2017 PharmacoEconomics open

76. Experiences of non-specialist nurses caring for patients and their significant others undergoing transitions during palliative end-of-life cancer care: a systematic review. (PubMed)

Experiences of non-specialist nurses caring for patients and their significant others undergoing transitions during palliative end-of-life cancer care: a systematic review. Non-specialist nurses, who are providing palliative end-of-life cancer care to patients and significant others undergoing psychosocial and existential transitions, may experience dissatisfaction, frustration and sorrow. On the other hand, they may also experience happiness, increased knowledge and personal growth.What (...) are non-specialist nurses' experiences when providing palliative end-of-life cancer care that involves the psychosocial and existential transitions of their patients and significant others?The current review considered studies that included a description of the experiences of non-specialist trained registered nurses (RNs) working in non-specialist wards.The current review considered studies that investigated experiences of RNs when providing palliative end-of-life cancer care that involves

2017 JBI database of systematic reviews and implementation reports

77. Early palliative care for adults with advanced cancer. (PubMed)

Early palliative care for adults with advanced cancer. Incurable cancer, which often constitutes an enormous challenge for patients, their families, and medical professionals, profoundly affects the patient's physical and psychosocial well-being. In standard cancer care, palliative measures generally are initiated when it is evident that disease-modifying treatments have been unsuccessful, no treatments can be offered, or death is anticipated. In contrast, early palliative care is initiated (...) much earlier in the disease trajectory and closer to the diagnosis of incurable cancer.To compare effects of early palliative care interventions versus treatment as usual/standard cancer care on health-related quality of life, depression, symptom intensity, and survival among adults with a diagnosis of advanced cancer.We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, the Cumulative Index to Nursing and Allied Health Literature (CINAHL), PsycINFO, OpenGrey

2017 Cochrane

78. Assessment tools for palliative care

Assessment tools for palliative care Assessment tools for palliative care Assessment tools for palliative care Aslakson R, Dy SM, Wilson RF, Waldfogel JM, Zhang A, Isenberg SR, Blair A, Sixon J, Robinson KA Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Aslakson R, Dy SM, Wilson RF, Waldfogel JM, Zhang A, Isenberg SR, Blair A, Sixon J, Robinson KA. Assessment (...) tools for palliative care. Rockville: Agency for Healthcare Research and Quality (AHRQ). Technical Brief No. 30. 2017 Authors' objectives To (1) provide an overview of palliative care assessment tools designed to be completed by or with patients or caregivers, including which tools have been applied to clinical care, as quality indicators, or in evaluations of interventions, and (2) identify needs for future palliative care assessment tool development and evaluation. Authors' conclusions We

2017 Health Technology Assessment (HTA) Database.

79. Palliative care for Parkinson’s disease: suggestions from a council of patient and carepartners (PubMed)

Palliative care for Parkinson’s disease: suggestions from a council of patient and carepartners In 2015, the Parkinson's Disease Foundation sponsored the first international meeting on Palliative Care and Parkinson's disease and the Patient Centered Outcomes Research Institute funded the first comparative effectiveness trial of palliative care for Parkinson's disease. A council of Parkinson's disease patients and carepartners was engaged to assist with both projects. This council wrote (...) the following manuscript as an opinion piece addressed to the clinical and research community on how palliative care could be applied to people living with Parkinson's disease and their families. The council endorses palliative care as an approach to the care of Parkinson's disease patients and their families that seeks to reduce suffering through spiritual, psychosocial, and medical support. This approach should start at the time of diagnosis, as this is a very challenging time for patients

Full Text available with Trip Pro

2017 NPJ Parkinson's disease

80. Drug therapy for symptoms associated with anxiety in adult palliative care patients. (PubMed)

Drug therapy for symptoms associated with anxiety in adult palliative care patients. This is an update of a Cochrane Review first published in 2004 (Issue 1) and previously updated in 2012 (Issue 10). Anxiety is common in palliative care patients. It can be a natural response to the complex uncertainty of having a life-limiting illness or impending death, but it may represent a clinically significant issue in its own right.To assess the effectiveness of drug therapy for treating symptoms (...) of drug therapy for the treatment of symptoms of anxiety in adult palliative care patients, that is, people with a known progressive life-limiting illness that is no longer responsive to curative treatment, including advanced heart, respiratory and neurological diseases (including dementia). Comparator treatments included placebo; another drug therapy or different dose schedule; or a non-drug intervention such as counselling, cognitive behaviour therapies or relaxation therapies.Two review authors

Full Text available with Trip Pro

2017 Cochrane