Latest & greatest articles for pain

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Top results for pain

161. Ketorolac for postoperative pain in children.

Ketorolac for postoperative pain in children. BACKGROUND: Children who undergo surgical procedures in ambulatory and inpatient settings are at risk of experiencing acute pain. Nonsteroidal anti-inflammatory drugs (NSAIDs) can reduce moderate to severe pain without many of the side effects associated with opioids. However, NSAIDs may cause bleeding, renal and gastrointestinal toxicity, and potentially delay wound and bone healing. Intravenous administration of ketorolac for postoperative pain (...) in children has not been approved in many countries, but is routinely administered in clinical practise. OBJECTIVES: To assess the efficacy and safety of ketorolac for postoperative pain in children. SEARCH METHODS: We searched the following databases, without language restrictions, to November 2017: CENTRAL (The Cochrane Library 2017, Issue 10); MEDLINE, Embase, and LILACS. We also checked clinical trials registers and reference lists of reviews, and retrieved articles for additional studies. SELECTION

Cochrane2018

162. Effectiveness of mobilization with movement (Mulligan concept techniques) on low back pain: a systematic review

Effectiveness of mobilization with movement (Mulligan concept techniques) on low back pain: a systematic review 29843520 2018 05 30 1477-0873 2018 May 01 Clinical rehabilitation Clin Rehabil Effectiveness of mobilization with movement (Mulligan concept techniques) on low back pain: a systematic review. 269215518778321 10.1177/0269215518778321 To evaluate evidence on the effectiveness of Mulligan techniques on low back pain. PubMed/Medline, Scopus, Ovid, CINAHL, Embase, PEDro, Google Scholar (...) , and Cochrane Library were searched from inception to 31 March 2018 for randomized clinical trials reporting outcomes of pain or disability in adult patients (⩾18 years) with low back pain. Two authors screened the results and extracted data for use in this review. The risk of bias was evaluated using the Cochrane criteria. Basic information and treatment protocols were also extracted. In addition, the level of evidence of each study and strength of conclusion for pain and disability were determined

EvidenceUpdates2018

163. Prospective Randomized Trial of Electrolysis for Chronic Plantar Heel Pain

Prospective Randomized Trial of Electrolysis for Chronic Plantar Heel Pain 29771148 2018 05 17 1944-7876 2018 May 01 Foot & ankle international Foot Ankle Int Prospective Randomized Trial of Electrolysis for Chronic Plantar Heel Pain. 1071100718773998 10.1177/1071100718773998 Chronic plantar heel pain (CPHP) is a common condition with high prevalence rates and a projected cost of treatment of US$192 to US$376 million. There are several therapeutic approaches and there is increased interest (...) in treatments aimed at the regeneration of tissues with poor healing potential. Our purpose was to investigate the effectiveness of ultrasound-guided percutaneous needle electrolysis in chronic plantar heel pain. A total of 73 patients with a clinical and ultrasonographic diagnosis of plantar heel pain unrelated to systemic inflammatory disease who had not received any other treatment in the previous 6 months on the affected foot were randomly allocated to receive either ultrasound-guided percutaneous

EvidenceUpdates2018

164. Meta-analysis evaluating music interventions for anxiety and pain in surgery

Meta-analysis evaluating music interventions for anxiety and pain in surgery 29665028 2018 05 14 1365-2168 105 7 2018 Jun The British journal of surgery Br J Surg Meta-analysis evaluating music interventions for anxiety and pain in surgery. 773-783 10.1002/bjs.10853 This study aimed to evaluate anxiety and pain following perioperative music interventions compared with control conditions in adult patients. Eleven electronic databases were searched for full-text publications of RCTs investigating (...) the effect of music interventions on anxiety and pain during invasive surgery published between 1 January 1980 and 20 October 2016. Results and data were double-screened and extracted independently. Random-effects meta-analysis was used to calculate effect sizes as standardized mean differences (MDs). Heterogeneity was investigated in subgroup analyses and metaregression analyses. The review was registered in the PROSPERO database as CRD42016024921. Ninety-two RCTs (7385 patients) were included

EvidenceUpdates2018

165. Effects of Electroacupuncture on Opioid Consumption in Patients with Chronic Musculoskeletal Pain: A Multicenter Randomized Controlled Trial

Effects of Electroacupuncture on Opioid Consumption in Patients with Chronic Musculoskeletal Pain: A Multicenter Randomized Controlled Trial 29893942 2018 06 12 1526-4637 2018 Jun 08 Pain medicine (Malden, Mass.) Pain Med Effects of Electroacupuncture on Opioid Consumption in Patients with Chronic Musculoskeletal Pain: A Multicenter Randomized Controlled Trial. 10.1093/pm/pny113 To evaluate the efficacy and safety of electroacupuncture in reducing opioid consumption in patients with chronic (...) musculoskeletal pain. A randomized, participant-assessor-blinded, three-arm trial. Participants from three pain clinics and from the public. One hundred and eight adults with chronic pain who were taking opioids. All participants received pain and medication management education. Participants were randomly allocated to electroacupuncture (N = 48), sham electroacupuncture (N = 29), or education alone (N = 31) to receive relevant treatment for 12 weeks. The last group received electroacupuncture during

EvidenceUpdates2018

166. Cortical Pain Response of Newborn Infants to Venepuncture: A Randomized Controlled Trial Comparing Analgesic Effects of Sucrose Versus Breastfeeding

Cortical Pain Response of Newborn Infants to Venepuncture: A Randomized Controlled Trial Comparing Analgesic Effects of Sucrose Versus Breastfeeding 29298184 2018 06 04 1536-5409 34 7 2018 Jul The Clinical journal of pain Clin J Pain Cortical Pain Response of Newborn Infants to Venepuncture: A Randomized Controlled Trial Comparing Analgesic Effects of Sucrose Versus Breastfeeding. 650-656 10.1097/AJP.0000000000000581 Sucrose administration and breastfeeding decrease behavioral expressions (...) of pain in neonates. However, recent studies indicated that there is a persistent cortical response with sucrose. This study compared the efficacy of sucrose administration versus breastfeeding to decrease cortical responses to pain during venepuncture. A randomized, prospective, controlled trial was conducted in a tertiary level maternity ward. Healthy, 3-day-old term neonates, undergoing venepuncture for neonatal screening, were randomly assigned to receive sucrose solution or be breastfed before

EvidenceUpdates2018

167. Effect of Intraoperative Platelet-Rich Plasma Treatment on Postoperative Donor Site Knee Pain in Patellar Tendon Autograft Anterior Cruciate Ligament Reconstruction: A Double-Blind Randomized Controlled Trial

Effect of Intraoperative Platelet-Rich Plasma Treatment on Postoperative Donor Site Knee Pain in Patellar Tendon Autograft Anterior Cruciate Ligament Reconstruction: A Double-Blind Randomized Controlled Trial 29741923 2018 06 29 1552-3365 46 8 2018 Jul The American journal of sports medicine Am J Sports Med Effect of Intraoperative Platelet-Rich Plasma Treatment on Postoperative Donor Site Knee Pain in Patellar Tendon Autograft Anterior Cruciate Ligament Reconstruction: A Double-Blind (...) Randomized Controlled Trial. 1827-1835 10.1177/0363546518769295 Donor site morbidity in the form of anterior knee pain is a frequent complication after bone-patellar tendon-bone (BPTB) autograft anterior cruciate ligament (ACL) reconstruction. Hypothesis/Purpose: The purpose was to examine the effect of the intraoperative administration of platelet-rich plasma (PRP) on postoperative kneeling pain. It was hypothesized that PRP treatment would reduce knee pain. Randomized controlled trial; Level

EvidenceUpdates2018

168. Effect of Low Back Pain Risk-Stratification Strategy on Patient Outcomes and Care Processes: the MATCH Randomized Trial in Primary Care

Effect of Low Back Pain Risk-Stratification Strategy on Patient Outcomes and Care Processes: the MATCH Randomized Trial in Primary Care 29790073 2018 05 23 1525-1497 2018 May 22 Journal of general internal medicine J Gen Intern Med Effect of Low Back Pain Risk-Stratification Strategy on Patient Outcomes and Care Processes: the MATCH Randomized Trial in Primary Care. 10.1007/s11606-018-4468-9 The STarT Back strategy for categorizing and treating patients with low back pain (LBP) improved (...) patients' function while reducing costs in England. This trial evaluated the effect of implementing an adaptation of this approach in a US setting. The Matching Appropriate Treatments to Consumer Healthcare needs (MATCH) trial was a pragmatic cluster randomized trial with a pre-intervention baseline period. Six primary care clinics were pair randomized, three to training in the STarT Back strategy and three to serve as controls. Adults receiving primary care for non-specific LBP were invited to provide

EvidenceUpdates2018

169. A randomized double-blind placebo-controlled trial on the effect of local analgesia on postoperative gluteal pain in patients undergoing sacrospinous ligament colpopexy

A randomized double-blind placebo-controlled trial on the effect of local analgesia on postoperative gluteal pain in patients undergoing sacrospinous ligament colpopexy 29614274 2018 05 25 1097-6868 218 6 2018 Jun American journal of obstetrics and gynecology Am. J. Obstet. Gynecol. A randomized double-blind placebo-controlled trial on the effect of local analgesia on postoperative gluteal pain in patients undergoing sacrospinous ligament colpopexy. 599.e1-599.e8 S0002-9378(18)30248-5 10.1016 (...) /j.ajog.2018.03.033 The incidence of temporary gluteal pain after sacrospinous ligament colpopexy ranges from 6.1% to 15.3%. Gluteal pain may occur as a result of injury to S3 to S5 nerve roots that course over the mid-portion of the coccygeus-sacrospinous ligament complex at the time of suspension suture placement. There are no data on the use of injections to prevent postoperative pain from nerve entrapment at the time of suture placement. The purpose of this study was to determine whether

EvidenceUpdates2018

170. Effect of Different Volumes on Pain Relief in Patient Receiving Fluoroscopic Guided Interlaminar Lumbar Epidural Steroid Injection

Effect of Different Volumes on Pain Relief in Patient Receiving Fluoroscopic Guided Interlaminar Lumbar Epidural Steroid Injection 29871368 2018 06 06 2150-1149 21 3 2018 May Pain physician Pain Physician Effect of Different Volumes on Pain Relief in Patient Receiving Fluoroscopic Guided Interlaminar Lumbar Epidural Steroid Injection. 243-250 Epidural steroids injections (ESI) are frequently used to treat lumbar radicular pain. Although different volume have been used for interlaminar ESI (...) in adults, there is no controlled trial comparing the effect of different volumes on pain relief for the same dose of steroid . To compare the effect of increase in volume of epidural drug on pain relief in lumbar ESI. Randomized double blind trial SETTING: Pain OR of a tertiary care centre METHODS: Sixty patients were randomly allocated to 1 of 3 groups: Group A (4 mL), Group B (6 mL), and Group C (8 mL). Pain was evaluated using visual analog scale (VAS) and improvement in disability using modified

EvidenceUpdates2018

171. Cebranopadol: A Novel, First-in-Class, Strong Analgesic: Results from a Randomized Phase IIa Clinical Trial in Postoperative Acute Pain

Cebranopadol: A Novel, First-in-Class, Strong Analgesic: Results from a Randomized Phase IIa Clinical Trial in Postoperative Acute Pain 29871387 2018 06 06 2150-1149 21 3 2018 May Pain physician Pain Physician Cebranopadol: A Novel, First-in-Class, Strong Analgesic: Results from a Randomized Phase IIa Clinical Trial in Postoperative Acute Pain. E193-E206 Cebranopadol is a potent, first-in-class analgesic with a novel mechanistic approach combining nociceptin/orphanin FQ peptide (NOP) and opioid (...) peptide receptor agonism. We aim to evaluate, for the first time, the analgesic efficacy, safety, and tolerability of cebranopadol in patients suffering from moderate to severe acute pain following bunionectomy. We conducted a phase IIa, randomized, multi-center, double-blind, double-dummy, placebo- and active-controlled, parallel group clinical trial. A total of 258 patients who underwent a primary bunionectomy were randomly assigned to receive a single oral administration of cebranopadol 200 µg, 400

EvidenceUpdates2018

172. Spinal manipulation and exercise for low back pain in adolescents: a randomized trial

Spinal manipulation and exercise for low back pain in adolescents: a randomized trial 29596158 2018 06 19 1872-6623 159 7 2018 Jul Pain Pain Spinal manipulation and exercise for low back pain in adolescents: a randomized trial. 1297-1307 10.1097/j.pain.0000000000001211 Low back pain (LBP) is common in adolescence, but there is a paucity of high-quality research to inform care. We conducted a multicenter randomized trial comparing 12 weeks of spinal manipulative therapy (SMT) combined (...) with exercise therapy (ET) to ET alone. Participants were 185 adolescents aged 12 to 18 years with chronic LBP. The primary outcome was LBP severity at 12, 26, and 52 weeks. Secondary outcomes included disability, quality of life, medication use, patient- and caregiver-rated improvement, and satisfaction. Outcomes were analyzed using longitudinal linear mixed effect models. An omnibus test assessing differences in individual outcomes over the entire year controlled for multiplicity. Of the 185 enrolled

EvidenceUpdates2018

173. The effectiveness of 12 weeks of Pilates intervention on disability, pain and kinesiophobia in patients with chronic low back pain: a randomized controlled trial

The effectiveness of 12 weeks of Pilates intervention on disability, pain and kinesiophobia in patients with chronic low back pain: a randomized controlled trial 29651872 2018 04 13 1477-0873 2018 Apr 01 Clinical rehabilitation Clin Rehabil The effectiveness of 12 weeks of Pilates intervention on disability, pain and kinesiophobia in patients with chronic low back pain: a randomized controlled trial. 269215518768393 10.1177/0269215518768393 To assess the effectiveness of 12 weeks of Pilates (...) practice on disability, pain and kinesiophobia in patients with chronic non-specific low back pain. This is a randomized controlled trial. This study was conducted in the university laboratory. A total of 64 participants with chronic non-specific low back pain were included. Participants were randomly allocated to intervention group consisted in Pilates intervention during 12 weeks ( n = 32) or control group who received no treatment ( n = 32). Disability, pain and kinesiophobia were assessed by Roland

EvidenceUpdates2018

174. Kinesio taping reduces elbow pain during resisted wrist extension in patients with chronic lateral epicondylitis: a randomized, double-blinded, cross-over study

Kinesio taping reduces elbow pain during resisted wrist extension in patients with chronic lateral epicondylitis: a randomized, double-blinded, cross-over study 29921250 2018 06 28 1471-2474 19 1 2018 Jun 19 BMC musculoskeletal disorders BMC Musculoskelet Disord Kinesio taping reduces elbow pain during resisted wrist extension in patients with chronic lateral epicondylitis: a randomized, double-blinded, cross-over study. 193 10.1186/s12891-018-2118-3 Lateral epicondylitis is frequently seen (...) in racquet sport players and the treatments are usually symptomatic rather than curative. Taping therapy is cheap and easy to apply in the sport field. In this study we valued the effectiveness of Kinesio taping (KT) on immediate pain control for patients with chronic lateral epicondylitis. We conducted a randomized, double-blinded, cross-over study with 15 patients with chronic lateral epicondylitis. All participants received two taping sessions in a random order with a 3-day interval in between: one

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

175. Hypnosis Enhances the Effects of Pain Education in Patients With Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial

Hypnosis Enhances the Effects of Pain Education in Patients With Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial 29654980 2018 06 16 1528-8447 2018 Apr 11 The journal of pain : official journal of the American Pain Society J Pain Hypnosis Enhances the Effects of Pain Education in Patients With Chronic Nonspecific Low Back Pain: A Randomized Controlled Trial. S1526-5900(18)30124-X 10.1016/j.jpain.2018.03.013 The potential benefits of combining pain education (PE) with clinical (...) hypnosis (CH) has not yet been investigated in individuals with chronic pain. A total of 100 patients with chronic nonspecific low back pain were randomized to receive either: 1) PE alone, or 2) PE with CH. Outcomes were collected by a blinded assessor at 2 weeks and 3 months after randomization. The primary outcomes were average pain intensity, worst pain intensity (both assessed with 11-point numeric rating scales), and disability (24-item Roland Morris Disability Questionnaire) at 2 weeks. At 2

EvidenceUpdates2018

176. Clonidine Effect on Pain After Cesarean Delivery: A Randomized Controlled Trial of Different Routes of Administration

Clonidine Effect on Pain After Cesarean Delivery: A Randomized Controlled Trial of Different Routes of Administration 29596102 2018 06 18 1526-7598 127 1 2018 Jul Anesthesia and analgesia Anesth. Analg. Clonidine Effect on Pain After Cesarean Delivery: A Randomized Controlled Trial of Different Routes of Administration. 165-170 10.1213/ANE.0000000000003319 Intrathecal clonidine prolongs spinal anesthesia. We evaluated the effects of the addition of intrathecal or intravenous clonidine (75 µg (...) ) to standard cesarean delivery spinal anesthesia on postoperative pain and neonatal outcomes. In a randomized, placebo-controlled, double-blind trial, 64 women scheduled for elective cesarean delivery under spinal anesthesia were randomly allocated and compared among 3 groups: intrathecal clonidine 75 µg, intravenous clonidine 75 µg, and placebo. The primary outcome was acute postoperative pain. A sample size of 26 individuals per group (N = 78) was planned. From April 2015 to April 2016, 64 women were

EvidenceUpdates2018

177. Neuropathic pain

Neuropathic pain Autosynthesis - Trip Database or use your Google+ account Liberating the literature My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search

Trip Evidence Maps2018

178. Low back pain

Low back pain Autosynthesis - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button

Trip Evidence Maps2018

179. Chronic pain

Chronic pain Autosynthesis - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button

Trip Evidence Maps2018

180. Low Back Pain, Adult Acute and Subacute

Low Back Pain, Adult Acute and Subacute Health Care Guideline: Adult Acute and Subacute Low Back Pain www.icsi.org Copyright © 2017 by Institute for Clinical Systems Improvement 1 Diagnosis Algorithm Text in blue in this algorithm indicates a linked corresponding annotation. Adult patient present with acute or subacute low back pain History and exam: • Pain characteristics • Sensory and strength changes • Prior treatment and response yes Complete assessment tools for pain and function (...) Incapacitating pain and/or advancing neurologic symptoms or other underlying pathology Consider re- evaluation, imaging or referral to specialist no Routine imaging is not recommended See Treatment Algorithm Acute 50) and failure to improve after one month had high false-positive rates. The authors concluded that red flags may be useful when combined or with a history of cancer, but by themselves will result in overtesting (Henschke, 2013). Fracture Single red flags that increase the likelihood of spinal

Institute for Clinical Systems Improvement2018