Latest & greatest articles for pain

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Top results for pain

41. Intravenous Dexamethasone Injection Reduces Pain From 12 to 21 Hours After Total Knee Arthroplasty: A Double-Blind, Randomized, Placebo-Controlled Trial (Abstract)

Intravenous Dexamethasone Injection Reduces Pain From 12 to 21 Hours After Total Knee Arthroplasty: A Double-Blind, Randomized, Placebo-Controlled Trial Pain after total knee arthroplasty (TKA) affects postoperative recovery and patient satisfaction. The analgesic benefits of corticosteroids have not been well studied. We, therefore, investigated the analgesic effects of intravenous (IV) dexamethasone (DEX) in patients undergoing a TKA.This was a randomized, double-blind, placebo-controlled (...) trial of 0.15 mg/kg of IV DEX vs saline placebo in unilateral TKA. Fifty patients/arm were recruited. Primary outcomes were pain level, determined by a visual analog scale, and the amount of morphine consumption (mg) ≤48 hours post-TKA. Secondary outcomes were rates of nausea and vomiting, C-reactive protein concentrations, and functional outcomes.The DEX group had a significantly lower mean visual analog scale score both at rest and during motion at 12, 15, 18, and 21 hours (P < .05). At 21 hours

2019 EvidenceUpdates

42. The Effect of Dexmedetomidine Added to Preemptive Ropivacaine Infiltration on Postoperative Pain After Lumbar Fusion Surgery: A Randomized Controlled Trial (Abstract)

The Effect of Dexmedetomidine Added to Preemptive Ropivacaine Infiltration on Postoperative Pain After Lumbar Fusion Surgery: A Randomized Controlled Trial A prospective and controlled study of dexmedetomidine added to preemptive ropivacaine infiltration in lumbar fusion surgery.Assessment of dexmedetomidine added to preemptive ropivacaine infiltration for the relief of postoperative pain after lumbar fusion surgery.Single local anesthetic preemptive wound infiltration for the relief (...) of postoperative pain does not translate into major or consistent clinical benefits after lumbar fusion surgery. Dexmedetomidine added to local anesthetics prolonged the duration of blockade and enhanced the analgesic in peripheral nerve block. The effect of dexmedetomidine added to preemptive ropivacaine infiltration in lumbar fusion surgery for the relief of postoperative pain has yet not been studied.Fifty-seven patients with elective posterior lumbar fusion were randomly divided into two groups. Five

2019 EvidenceUpdates

43. Pentosan polysulfate sodium for treating bladder pain syndrome

Pentosan polysulfate sodium for treating bladder pain syndrome Pentosan polysulfate sodium for treating bladder pain syndrome T echnology appraisal guidance Published: 13 November 2019 www.nice.org.uk/guidance/ta610 © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of- rights).Y Y our responsibility our responsibility The recommendations in this guidance represent the view of NICE, arrived at after careful consideration (...) to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Pentosan polysulfate sodium for treating bladder pain syndrome (TA610) © NICE 2019. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and- conditions#notice-of-rights). Page 2 of 25Contents Contents 1 Recommendations 4 2 Information about pentosan polysulfate sodium 6 3 Committee discussion 7

2019 National Institute for Health and Clinical Excellence - Technology Appraisals

44. Efficacy of Systemic Steroid Use Given One Day After Total Knee Arthroplasty for Pain and Nausea: A Randomized Controlled Study Full Text available with Trip Pro

Efficacy of Systemic Steroid Use Given One Day After Total Knee Arthroplasty for Pain and Nausea: A Randomized Controlled Study Systemic steroid has been used to control pain and nausea in total knee arthroplasty (TKA), but most studies recommend a single dose administration prior to, or during, surgery. This study aimed to determine the efficacy of administration on 1 day postoperatively.Patients who were scheduled to undergo TKA were randomly assigned to the following groups: control group (...) , receiving normal saline injection; group 1, receiving 10 mg dexamethasone intravenously (IV) 1 hour before surgery; group 2, receiving 0.1 mg/kg dexamethasone (IV) 24 hours after surgery; or group 3, receiving 0.2 mg/kg dexamethasone (IV) 24 hours after surgery (n = 44-46 per group). Primary outcomes were pain and nausea visual analogue scale (VAS). Secondary outcomes were analgesic administration, rescue antiemetic administration, C-reactive protein, range of motion, and complications.Postoperative

2019 EvidenceUpdates

45. Is a combined programme of manual therapy and exercise more effective than usual care in patients with non-specific chronic neck pain? A randomized controlled trial (Abstract)

Is a combined programme of manual therapy and exercise more effective than usual care in patients with non-specific chronic neck pain? A randomized controlled trial The aim of this study was to compare the effectiveness of a combined intervention of manual therapy and exercise (MET) versus usual care (UC), on disability, pain intensity and global perceived recovery, in patients with non-specific chronic neck pain (CNP).Randomized controlled trial.Outpatient care units.Sixty-four non-specific (...) CNP patients were randomly allocated to MET (n = 32) or UC (n = 32) groups.Participants in the MET group received 12 sessions of mobilization and exercise, whereas the UC group received 15 sessions of usual care in physiotherapy.The primary outcome was disability (Neck Disability Index). The secondary outcomes were pain intensity (Numeric Pain Rating Scale) and global perceived recovery (Patient Global Impression Change). Patients were assessed at baseline, three weeks, six weeks (end of treatment

2019 EvidenceUpdates

46. Managing pain and distress in children undergoing brief diagnostic and therapeutic procedures

Managing pain and distress in children undergoing brief diagnostic and therapeutic procedures Common medical procedures to assess and treat patients can cause significant pain and distress. Clinicians should have a basic approach for minimizing pain and distress in children, particularly for frequently used diagnostic and therapeutic procedures. This statement focuses on infants (excluding care provided in the NICU), children, and youth who are undergoing common, minor but painful medical (...) procedures. Simple, evidence-based strategies for managing pain and distress are reviewed, with guidance for integrating them into clinical practice as an essential part of health care. Health professionals are encouraged to use minimally invasive approaches and, when painful procedures are unavoidable, to combine simple pain and distress-minimizing strategies to improve the patient, parent, and health care provider experience. Health administrators are encouraged to create institutional policies

2019 Canadian Paediatric Society

47. Guiding Therapy by Coronary CT Angiography Improves Outcomes in Patients With Stable Chest Pain Full Text available with Trip Pro

Guiding Therapy by Coronary CT Angiography Improves Outcomes in Patients With Stable Chest Pain Within the SCOT-HEART (Scottish COmputed Tomography of the HEART Trial) trial of patients with stable chest pain, the use of coronary computed tomography angiography (CTA) reduced the rate of death from coronary heart disease or nonfatal myocardial infarction (primary endpoint).This study sought to assess the consistency and mechanisms of the 5-year reduction in this endpoint.In this open-label trial

2019 EvidenceUpdates

48. Mind-Body Therapies for Opioid-Treated Pain: A Systematic Review and Meta-analysis (Abstract)

Mind-Body Therapies for Opioid-Treated Pain: A Systematic Review and Meta-analysis Mind-body therapies (MBTs) are emerging as potential tools for addressing the opioid crisis. Knowing whether mind-body therapies may benefit patients treated with opioids for acute, procedural, and chronic pain conditions may be useful for prescribers, payers, policy makers, and patients.To evaluate the association of MBTs with pain and opioid dose reduction in a diverse adult population with clinical pain.For (...) this systematic review and meta-analysis, the MEDLINE, Embase, Emcare, CINAHL, PsycINFO, and Cochrane Library databases were searched for English-language randomized clinical trials and systematic reviews from date of inception to March 2018. Search logic included (pain OR analgesia OR opioids) AND mind-body therapies. The gray literature, ClinicalTrials.gov, and relevant bibliographies were also searched.Randomized clinical trials that evaluated the use of MBTs for symptom management in adults also

2019 EvidenceUpdates

49. Treatment for Acute Pain: An Evidence Map

Treatment for Acute Pain: An Evidence Map Treatment for Acute Pain: An Evidence Map Technical Brief Number 33 RTechnical Brief Number 33 Treatment for Acute Pain: An Evidence Map Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 5600 Fishers Lane Rockville, MD 20857 www.ahrq.gov Contract No. 290-2015-0000-81 Prepared by: Minnesota Evidence-based Practice Center Minneapolis, MN Investigators: Michelle Brasure, Ph.D., M.S.P.H., M.L.I.S. Victoria (...) A. Nelson, M.Sc. Shellina Scheiner, PharmD, B.C.G.P. Mary L. Forte, Ph.D., D.C. Mary Butler, Ph.D., M.B.A. Sanket Nagarkar, D.D.S., M.P.H. Jayati Saha, Ph.D. Timothy J. Wilt, M.D., M.P.H. AHRQ Publication No. 19(20)-EHC022-EF Oct ober 2019 ii Key Messages Purpose of review The purpose of this evidence map is to provide a high-level overview of the current guidelines and systematic reviews on pharmacologic and nonpharmacologic treatments for acute pain. We map the evidence for several acute pain

2019 Effective Health Care Program (AHRQ)

50. Oral COX-2 inhibitors for pain

Oral COX-2 inhibitors for pain '); } else { document.write(' '); } ACE | Oral COX-2 inhibitors for treating pain Search > > Oral COX-2 inhibitors for treating pain - Oral COX-2 inhibitors for treating pain Published on 2 September 2019 Guidance Recommendations The Ministry of Health's Drug Advisory Committee has recommended: celecoxib 200 mg capsule; and etoricoxib 60 mg, 90 mg and 120 mg tablets for treating pain in line with their registered indications in Singapore. For patients with renal

2019 Appropriate Care Guides, Agency for Care Effectiveness (Singapore)

51. Stressed out about stress testing? The utility of stress testing after non-ACS chest pain Full Text available with Trip Pro

Stressed out about stress testing? The utility of stress testing after non-ACS chest pain Stressed out about stress testing? The utility of stress testing after non-ACS chest pain - CanadiEM Stressed out about stress testing? The utility of stress testing after non-ACS chest pain In by Vivian Tam October 15, 2019 The Case Your next patient in the acute zone of the ED is Mr. Liu, a 53-year old man presenting with one hour of acute onset atypical chest pain. He has several risk factors (...) ​ A review of the evidence on stress testing A recent disputed the commonly cited 2% ACS miss rate after ED discharge. ​4​ In the Pope et al . study, of the 10,689 patients presenting with undifferentiated chest pain, 889 patients had acute MI. ​5​ Nineteen of the confirmed MI patients were mistakenly discharged. Therefore, of all patients presenting to the ED with undifferentiated chest pain, less than 0.2% were missed (whereas the 2% figure is derived from the 19 missed MIs of the 889 patients

2019 CandiEM

52. Inhaled nitric oxide for treating pain crises in people with sickle cell disease. (Abstract)

Inhaled nitric oxide for treating pain crises in people with sickle cell disease. In people with sickle cell disease, sickled red blood cells cause the occlusion of small blood vessels which presents as episodes of severe pain known as pain crises or vaso-occlusive crises. The pain can occur in the bones, chest, or other parts of the body, and may last several hours to days. Pain relief during crises includes both pharmacologic and non-pharmacologic treatments. The efficacy of inhaled nitric (...) oxide in pain crises has been a controversial issue and hypotheses have been made suggesting a beneficial response due to its vasodilator properties. Yet no conclusive evidence has been presented.This review aims to evaluate the available randomised controlled studies which address this topic.To capture the available body of evidence evaluating the efficacy and safety of the use of inhaled nitric oxide in treating pain crises in people with sickle cell disease; and to assess the treatment's

2019 Cochrane

53. Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome. (Abstract)

Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome. Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common disorder in which the two main clinical features are pelvic pain and lower urinary tract symptoms. There are currently many approaches for its management, using both pharmacological and non-pharmacological interventions. The National Institute of Health - Chronic Prostatitis Symptom Index (NIH-CPSI) score is a validated measure (...) commonly used to measure CP/CPPS symptoms. We considered a 25% decrease of NIH-CPSI baseline score or a six-point reduction as MCID.To assess the effects of pharmacological therapies for chronic prostatitis/chronic pelvic pain syndrome.We performed a comprehensive search using CENTRAL, MEDLINE, Embase, PsycINFO, CINAHL, trial registries, grey literature and conference proceedings, with no restrictions on the language of publication or publication status. The date of the latest search of all databases

2019 Cochrane

54. Tiered Care for Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines

Tiered Care for Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Tiered Care for Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Tiered Care for Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Tiered Care for Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-Effectiveness (...) , and Guidelines Last updated: February 12, 2019 Project Number: RC1074-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of tiered or stepped care for patients with chronic, non-malignant pain in outpatient settings? What is the cost-effectiveness of tiered or stepped care for patients with chronic, non-malignant pain in outpatient settings? What are the evidence-based guidelines regarding tiered

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

55. Multidisciplinary Treatment Programs for Patients with Acute or Subacute Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines

Multidisciplinary Treatment Programs for Patients with Acute or Subacute Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Multidisciplinary Treatment Programs for Patients with Acute or Subacute Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Multidisciplinary Treatment Programs for Patients with Acute or Subacute Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines (...) Multidisciplinary Treatment Programs for Patients with Acute or Subacute Pain: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Last updated: May 7, 2019 Project Number: RC1109-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of multidisciplinary treatment programs for patients with acute or subacute pain in outpatient settings? What is the cost-effectiveness

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

56. Multidisciplinary Treatment Programs for Patients with Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-effectiveness, and Guidelines – An Update

Multidisciplinary Treatment Programs for Patients with Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-effectiveness, and Guidelines – An Update Multidisciplinary Treatment Programs for Patients with Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-effectiveness, and Guidelines – An Update | CADTH.ca Find the information you need Multidisciplinary Treatment Programs for Patients with Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost (...) -effectiveness, and Guidelines – An Update Multidisciplinary Treatment Programs for Patients with Chronic Non-Malignant Pain: A Review of Clinical Effectiveness, Cost-effectiveness, and Guidelines – An Update Last updated: May 10, 2019 Project Number: RC1110-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of multidisciplinary treatment programs for patients with chronic, non-malignant pain

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

57. Yoga for Chronic Non-Malignant Pain Management: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines

Yoga for Chronic Non-Malignant Pain Management: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines Yoga for Chronic Non-Malignant Pain Management: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines | CADTH.ca Find the information you need Yoga for Chronic Non-Malignant Pain Management: A Review of Clinical Effectiveness, Cost-Effectiveness and Guidelines Yoga for Chronic Non-Malignant Pain Management: A Review of Clinical Effectiveness, Cost-Effectiveness (...) and Guidelines Last updated: July 8, 2019 Project Number: RC1139-000 Product Line: Research Type: Devices and Systems Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of yoga for chronic non-malignant pain in adults? What is the cost-effectiveness of yoga for chronic non-malignant pain in adults? What are the evidence-based guidelines regarding the use of yoga for chronic non-malignant pain in adults? Key Message Evidence of limited quality from one

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

58. Medical Cannabis for the Treatment of Chronic Pain: A Review of Clinical Effectiveness and Guidelines

Medical Cannabis for the Treatment of Chronic Pain: A Review of Clinical Effectiveness and Guidelines Medical Cannabis for the Treatment of Chronic Pain: A Review of Clinical Effectiveness and Guidelines | CADTH.ca Find the information you need Medical Cannabis for the Treatment of Chronic Pain: A Review of Clinical Effectiveness and Guidelines Medical Cannabis for the Treatment of Chronic Pain: A Review of Clinical Effectiveness and Guidelines Last updated: July 24, 2019 Project Number: RC1153 (...) -000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of medical cannabis for the treatment of chronic pain? What are the evidence-based guidelines associated with the use of medical cannabis for the treatment of chronic pain? Key Message Based on four overviews (with overlapping systematic reviews), and one systematic review of guidelines,8 there is some suggestion of benefit with cannabis-based medicines

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

59. Timing of Pain Reassessment Post-Pharmacological Treatment Administration in Hospitals: Guidelines

Timing of Pain Reassessment Post-Pharmacological Treatment Administration in Hospitals: Guidelines Timing of Pain Reassessment Post-Pharmacological Treatment Administration in Hospitals: Guidelines | CADTH.ca Find the information you need Timing of Pain Reassessment Post-Pharmacological Treatment Administration in Hospitals: Guidelines Timing of Pain Reassessment Post-Pharmacological Treatment Administration in Hospitals: Guidelines Last updated: August 2, 2019 Project Number: RA1051-000 (...) Product Line: Research Type: Devices and Systems Report Type: Reference List Result type: Report Question What are the evidence-based guidelines regarding frequency and timing of pain reassessment following medication administration in hospital? Key Message Three evidence-based guidelines were identified regarding frequency and timing of pain reassessment following medication administration in hospital. Files Rapid Response Reference List Published : August 2, 2019 Related Content Follow us: © 2019

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review

60. Multidisciplinary Pain Consult Teams for Acute Care in Hospitals: Clinical Utility and Cost-Effectiveness

Multidisciplinary Pain Consult Teams for Acute Care in Hospitals: Clinical Utility and Cost-Effectiveness Multidisciplinary Pain Consult Teams for Acute Care in Hospitals: Clinical Utility and Cost-Effectiveness | CADTH.ca Find the information you need Multidisciplinary Pain Consult Teams for Acute Care in Hospitals: Clinical Utility and Cost-Effectiveness Multidisciplinary Pain Consult Teams for Acute Care in Hospitals: Clinical Utility and Cost-Effectiveness Last updated: August 16, 2019 (...) Project Number: RB1357-000 Product Line: Research Type: Devices and Systems Report Type: Summary of Abstracts Result type: Report Question What is the clinical utility of acute pain assessment by multidisciplinary pain consult teams in an inpatient setting? What is the cost-effectiveness of acute pain assessment by multidisciplinary pain consult teams in an inpatient setting? Key Message No relevant health technology assessments, systematic reviews, meta-analyses, randomized controlled trials, non

2019 Canadian Agency for Drugs and Technologies in Health - Rapid Review