Latest & greatest articles for overdiagnosis

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Top results for overdiagnosis

1. Overdiagnosis in primary care: framing the problem and finding solutions.

Overdiagnosis in primary care: framing the problem and finding solutions. Overdiagnosis, is defined as the diagnosis of a condition that, if unrecognized, would not cause symptoms or harm a patient during his or her lifetime, and it is increasingly acknowledged as a consequence of screening for cancer and other conditions. Because preventive care is a crucial component of primary care, which is delivered to the broad population, overdiagnosis in primary care is an important problem from (...) a public health perspective and has far reaching implications. The scope of overdiagnosis as a result of services delivered in primary care is unclear, though overdiagnosis of indolent breast, prostate, thyroid, and lung cancers is well described and overdiagnosis of chronic kidney disease, depression, and attention-deficit/hyperactivity disorder is also recognized. However, overdiagnosis is a known consequence of all screening and can be assumed to occur in many more clinical contexts. Overdiagnosis

BMJ2018

2. Overdiagnosis

Overdiagnosis Top results for overdiagnosis - Trip Database or use your Google+ account Liberating the literature My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing (...) the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for overdiagnosis The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines

Trip Latest and Greatest2018

3. Defining, Estimating, and Communicating Overdiagnosis in Cancer Screening.

Defining, Estimating, and Communicating Overdiagnosis in Cancer Screening. The toll of inadequate health care is well-substantiated, but recognition is mounting that "too much" is also possible. Overdiagnosis represents one harm of too much medicine, but the concept can be confusing: It is often conflated with related harms (such as overtreatment, misclassification, false-positive results, and overdetection) and is difficult to measure because it cannot be directly observed. Because the U.S (...) . Preventive Services Task Force (USPSTF) issues screening recommendations aimed largely at healthy persons, it has a particular interest in understanding harms related to screening, especially but not limited to overdiagnosis. In support of the USPSTF, the authors summarize the knowledge and provide guidance on defining, estimating, and communicating overdiagnosis in cancer screening. To improve consistency, thinking, and reporting about overdiagnosis, they suggest a specific definition. The authors

Annals of Internal Medicine2018

4. Effectiveness of and overdiagnosis from mammography screening in the Netherlands: population based study.

Effectiveness of and overdiagnosis from mammography screening in the Netherlands: population based study. Objective To analyse stage specific incidence of breast cancer in the Netherlands where women have been invited to biennial mammography screening since 1989 (ages 50-69) and 1997 (ages 70-75), and to assess changes in breast cancer mortality and quantified overdiagnosis. Design Population based study. Setting Mammography screening programme, the Netherlands. Participants Dutch women of all (...) ages, 1989 to 2012. Main outcome measures Stage specific age adjusted incidence of breast cancer from 1989 to 2012. The extra numbers of in situ and stage 1 breast tumours associated with screening were estimated by comparing rates in women aged 50-74 with those in age groups not invited to screening. Overdiagnosis was estimated after subtraction of the lead time cancers. Breast cancer mortality reductions and overdiagnosis during 2010-12 were computed without (scenario 1) and with (scenario 2

BMJ2017 Full Text: Link to full Text with Trip Pro

5. Rising Thyroid Cancer Incidence in Southern India: An Epidemic of Overdiagnosis?

Rising Thyroid Cancer Incidence in Southern India: An Epidemic of Overdiagnosis? 29264503 2018 11 13 2472-1972 1 5 2017 May 01 Journal of the Endocrine Society J Endocr Soc Rising Thyroid Cancer Incidence in Southern India: An Epidemic of Overdiagnosis? 480-487 10.1210/js.2017-00097 Thyroid cancer incidence is rising in high-income countries. This increase in disease burden is attributed to the phenomenon of overdiagnosis. We aimed to investigate trends in thyroid cancer rates in India (...) diagnosed in Thiruvananthapuram, and large numbers of patients were <40 years of age. The AARm remained stable in all regions. We reported a high burden of thyroid cancer in Kerala, India, which is most likely due to overdiagnosis. Mathew Indu Elizabeth IE Department of Internal Medicine, Division of Endocrinology, University of Kentucky Medical Center, Lexington, Kentucky 40536. Mathew Aju A Department of Internal Medicine, Division of Medical Oncology, University of Kentucky, Markey Cancer Center

Journal of the Endocrine Society2017 Full Text: Link to full Text with Trip Pro

6. Breast Cancer Screening in Denmark: A Cohort Study of Tumor Size and Overdiagnosis.

Breast Cancer Screening in Denmark: A Cohort Study of Tumor Size and Overdiagnosis. Background: Effective breast cancer screening should detect early-stage cancer and prevent advanced disease. Objective: To assess the association between screening and the size of detected tumors and to estimate overdiagnosis (detection of tumors that would not become clinically relevant). Design: Cohort study. Setting: Denmark from 1980 to 2010. Participants: Women aged 35 to 84 years. Intervention: Screening (...) programs offering biennial mammography for women aged 50 to 69 years beginning in different regions at different times. Measurements: Trends in the incidence of advanced (>20 mm) and nonadvanced (≤20 mm) breast cancer tumors in screened and nonscreened women were measured. Two approaches were used to estimate the amount of overdiagnosis: comparing the incidence of advanced and nonadvanced tumors among women aged 50 to 84 years in screening and nonscreening areas; and comparing the incidence

Annals of Internal Medicine2017

7. Breast-Cancer Tumor Size, Overdiagnosis, and Mammography Screening Effectiveness.

Breast-Cancer Tumor Size, Overdiagnosis, and Mammography Screening Effectiveness. BACKGROUND: The goal of screening mammography is to detect small malignant tumors before they grow large enough to cause symptoms. Effective screening should therefore lead to the detection of a greater number of small tumors, followed by fewer large tumors over time. METHODS: We used data from the Surveillance, Epidemiology, and End Results (SEER) program, 1975 through 2012, to calculate the tumor-size

NEJM2016

8. Worldwide Thyroid-Cancer Epidemic? The Increasing Impact of Overdiagnosis.

Worldwide Thyroid-Cancer Epidemic? The Increasing Impact of Overdiagnosis. Worldwide Thyroid-Cancer Epidemic? The Increasing Impact of Overdiagnosis. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 27532827 (...) Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2016 Aug 18;375(7):614-7. doi: 10.1056/NEJMp1604412. Worldwide Thyroid-Cancer Epidemic? The Increasing Impact of Overdiagnosis. 1 , 1 , 1 , 1 , 1 , 1 . 1 From the International Agency for Research on Cancer, Lyon, France (S.V., S.F., F.B., C.P.W., M.P.); and the Cancer Epidemiology

NEJM2016

9. Observational study: US counties with higher rates of breast cancer screening have higher rates of incidence with no concomitant decrease in breast cancer mortality suggesting overdiagnosis

Observational study: US counties with higher rates of breast cancer screening have higher rates of incidence with no concomitant decrease in breast cancer mortality suggesting overdiagnosis US counties with higher rates of breast cancer screening have higher rates of incidence with no concomitant decrease in breast cancer mortality suggesting overdiagnosis | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your (...) overdiagnosis Article Text Therapeutics/Prevention Observational study US counties with higher rates of breast cancer screening have higher rates of incidence with no concomitant decrease in breast cancer mortality suggesting overdiagnosis Rebecca A Hubbard Statistics from Altmetric.com No Altmetric data available for this article. Commentary on: Harding C , Pompei F , Burmistrov D , et al . Breast Cancer Screening, Incidence, and Mortality Across US Counties . Request permissions If you wish to reuse any

Evidence-Based Medicine (Requires free registration)2015

10. Qualitative?other: Overdiagnosis in breast cancer screening: women have minimal prior awareness of the issue, and their screening intentions are influenced by the size of the risk

Qualitative?other: Overdiagnosis in breast cancer screening: women have minimal prior awareness of the issue, and their screening intentions are influenced by the size of the risk Overdiagnosis in breast cancer screening: women have minimal prior awareness of the issue, and their screening intentions are influenced by the size of the risk | Evidence-Based Nursing This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in via your Society Log in using (...) your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in via your Society Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Overdiagnosis in breast cancer screening: women have minimal prior awareness of the issue, and their screening intentions

Evidence-Based Nursing2014

11. Overdiagnosis from mammographic screening

Overdiagnosis from mammographic screening Overdiagnosis from mammographic screening | Cancer Australia ") //--> ") //--> Search form Search You are here » » Loading cart Revised & updated: 2014 , 2010 Published: 2008 This position statement has been endorsed by the Australian Health Ministers’ Advisory Council Standing Committee on Screening, Cancer Council Australia and the Royal Australian and New Zealand College of Radiologists, and is supported by the Cancer Australia Advisory Council (...) . Context National Breast and Ovarian Cancer Centre* first released a position statement on overdiagnosis from mammographic screening in 2008, followed by an update in 2010. The present statement is a further update by Cancer Australia. This update was based on a review of the published scientific literature and incorporation of input from international and national experts in the field. Cancer Australia position statements address significant clinical issues, emerging issues in cancer control

MHRA Drug Safety Update2014

12. Overdiagnosis from mammography screening

Overdiagnosis from mammography screening Overdiagnosis from mammographic screening | Cancer Australia ") //--> ") //--> Search form Search You are here » » Loading cart Revised & updated: 2014 , 2010 Published: 2008 This position statement has been endorsed by the Australian Health Ministers’ Advisory Council Standing Committee on Screening, Cancer Council Australia and the Royal Australian and New Zealand College of Radiologists, and is supported by the Cancer Australia Advisory Council (...) . Context National Breast and Ovarian Cancer Centre* first released a position statement on overdiagnosis from mammographic screening in 2008, followed by an update in 2010. The present statement is a further update by Cancer Australia. This update was based on a review of the published scientific literature and incorporation of input from international and national experts in the field. Cancer Australia position statements address significant clinical issues, emerging issues in cancer control

Cancer Australia2014

13. Influence of study features and methods on overdiagnosis estimates in breast and prostate cancer screening.

Influence of study features and methods on overdiagnosis estimates in breast and prostate cancer screening. Knowledge of the likelihood that a screening-detected case of cancer has been overdiagnosed is vitally important to make treatment decisions and develop screening policy. An overdiagnosed case is an excess case detected by screening. Estimates of the frequency of overdiagnosis in breast and prostate cancer screening vary greatly across studies. This article identifies features (...) of overdiagnosis studies that influence results and shows their effect by using published research. First, different ways to define and measure overdiagnosis are considered. Second, contextual features and how they affect overdiagnosis estimates are examined. Third, the effect of estimation approach is discussed. Many studies use excess incidence under screening as a proxy for overdiagnosis. Others use statistical models to make inferences about lead time or natural history and then derive the corresponding

Annals of Internal Medicine2013 Full Text: Link to full Text with Trip Pro

14. Overdiagnosis in screening mammography in Denmark: population based cohort study.

Overdiagnosis in screening mammography in Denmark: population based cohort study. OBJECTIVE: To use data from two longstanding, population based screening programmes to study overdiagnosis in screening mammography. DESIGN: Population based cohort study. SETTING: Copenhagen municipality (from 1991) and Funen County (from 1993), Denmark. PARTICIPANTS: 57,763 women targeted by organised screening, aged 56-69 when the screening programmes started, and followed up to 2009. MAIN OUTCOME MEASURES (...) : Overdiagnosis of breast cancer in women targeted by screening, assessed by relative risks compared with historical control groups from screening regions, national control groups from non-screening regions, and historical national control groups. RESULTS: In total, 3279 invasive breast carcinomas and ductal carcinomas in situ occurred. The start of screening led to prevalence peaks in breast cancer incidence: relative risk 2.06 (95% confidence interval 1.64 to 2.59) for Copenhagen and 1.84 (1.46 to 2.32

BMJ2013 Full Text: Link to full Text with Trip Pro

15. Women's views on overdiagnosis in breast cancer screening: a qualitative study.

Women's views on overdiagnosis in breast cancer screening: a qualitative study. OBJECTIVE: To elicit women's responses to information about the nature and extent of overdiagnosis in mammography screening (detecting disease that would not present clinically during the woman's lifetime) and explore how awareness of overdiagnosis might influence attitudes and intentions about screening. DESIGN: Qualitative study using focus groups that included a presentation explaining overdiagnosis (...) , incorporating different published estimates of its rate (1-10%, 30%, 50%) and information on the mortality benefit of screening, with guided group discussions SETTING: Sydney, Australia PARTICIPANTS: Fifty women aged 40-79 years with no personal history of breast cancer and with varying levels of education and participation in screening. RESULTS: Prior awareness of breast cancer overdiagnosis was minimal. Women generally reacted with surprise, but most came to understand the issue. Responses

BMJ2013 Full Text: Link to full Text with Trip Pro

16. Observational study: Mammography screening in Norway caused substantial overdiagnosis and did not reduce late-stage breast cancers

Observational study: Mammography screening in Norway caused substantial overdiagnosis and did not reduce late-stage breast cancers Mammography screening in Norway caused substantial overdiagnosis and did not reduce late-stage breast cancers | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user (...) name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Mammography screening in Norway caused substantial overdiagnosis and did not reduce late-stage breast cancers Article Text Online articles Observational study Mammography screening in Norway caused substantial overdiagnosis and did not reduce late-stage breast

Evidence-Based Medicine (Requires free registration)2013

17. Estimating overdiagnosis in low-dose computed tomography screening for lung cancer: a cohort study.

Estimating overdiagnosis in low-dose computed tomography screening for lung cancer: a cohort study. BACKGROUND: Lung cancer screening may detect cancer that will never become symptomatic (overdiagnosis), leading to overtreatment. Changes in size on sequential low-dose computed tomography (LDCT) screening, expressed as volume-doubling time (VDT), may help to distinguish aggressive cancer from cases that are unlikely to become symptomatic. OBJECTIVE: To assess VDT for screening-detected lung (...) cancer as an indicator of overdiagnosis. DESIGN: Retrospective estimation of the VDT of cancer detected in a prospective LDCT screening cohort. SETTING: Nonrandomized, single-center screening study involving persons at high risk for lung cancer enrolled between 2004 and 2005 who received LDCT annually for 5 years. PATIENTS: 175 study patients diagnosed with primary lung cancer. MEASUREMENTS: VDT was measured on LDCT and classified as fast-growing (&lt;400 days), slow-growing (between 400 and 599

Annals of Internal Medicine2012

18. Overdiagnosis of invasive breast cancer due to mammography screening: results from the norwegian screening program.

Overdiagnosis of invasive breast cancer due to mammography screening: results from the norwegian screening program. BACKGROUND: Precise quantification of overdiagnosis of breast cancer (defined as the percentage of cases of cancer that would not have become clinically apparent in a woman's lifetime without screening) due to mammography screening has been hampered by lack of valid comparison groups that identify incidence trends attributable to screening versus those due to temporal trends (...) in incidence. OBJECTIVE: To estimate the percentage of overdiagnosis of breast cancer attributable to mammography screening. DESIGN: Comparison of invasive breast cancer incidence with and without screening. SETTING: A nationwide mammography screening program in Norway (inviting women aged 50 to 69 years), gradually implemented from 1996 to 2005. PARTICIPANTS: The Norwegian female population. MEASUREMENTS: Concomitant incidence of invasive breast cancer from 1996 to 2005 in counties where the screening

Annals of Internal Medicine2012

19. Overdiagnosis from non-progressive cancer detected by screening mammography: stochastic simulation study with calibration to population based registry data.

Overdiagnosis from non-progressive cancer detected by screening mammography: stochastic simulation study with calibration to population based registry data. OBJECTIVE: To quantify the magnitude of overdiagnosis from non-progressive disease detected by screening mammography, after adjustment for the potential for lead time bias, secular trend in the underlying risk of breast cancer, and opportunistic screening. DESIGN: Approximate bayesian computation analysis with a stochastic simulation model (...) designed to replicate standardised incidence rates of breast cancer. The model components included the lifetime probability of breast cancer, the natural course of breast cancer, and participation in organised and opportunistic mammography screening. SETTING: Isère, a French administrative region with nearly 1.2 million inhabitants. PARTICIPANTS: All women living in Isère and aged 50-69 during 1991-2006. MAIN OUTCOME MEASURES: Overdiagnosis, defined as the proportion of non-progressive cancers among

BMJ2011 Full Text: Link to full Text with Trip Pro

20. Overdiagnosis in publicly organised mammography screening programmes: systematic review of incidence trends

Overdiagnosis in publicly organised mammography screening programmes: systematic review of incidence trends Overdiagnosis in publicly organised mammography screening programmes: systematic review of incidence trends Overdiagnosis in publicly organised mammography screening programmes: systematic review of incidence trends Jorgensen K J, Gotzsche P C CRD summary This review found that an increase in breast cancer incidence was closely related to introduction of screening, and concluded that one (...) in three breast cancers in a population offered organised screening is overdiagnosed. Methodological limitations, including estimation of results from multiple statistical models, warrant cautious interpretation of the numbers of overdiagnosed cases. The increase in incidence is a valid conclusion. Authors' objectives To determine the extent of overdiagnosis of breast cancer in publicly organised screening programmes. Searching PubMed was searched (up to April 2007) for articles published after 1990

DARE.2009