Latest & greatest articles for otitis media

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Top results for otitis media

161. Efficacy of amoxicillin with and without decongestant-antihistamine for otitis media with effusion in children. Results of a double-blind, randomized trial.

Efficacy of amoxicillin with and without decongestant-antihistamine for otitis media with effusion in children. Results of a double-blind, randomized trial. 2880294 1987 03 11 1987 03 11 2013 11 21 0028-4793 316 8 1987 Feb 19 The New England journal of medicine N. Engl. J. Med. Efficacy of amoxicillin with and without decongestant-antihistamine for otitis media with effusion in children. Results of a double-blind, randomized trial. 432-7 In a randomized, double-blind, placebo-controlled trial (...) involving 518 infants and children who had otitis media with effusion ("secretory" otitis media), we evaluated the efficacy of a two-week course of amoxicillin (40 mg per kilogram of body weight per day) with and without a four-week course of an oral decongestant-antihistamine combination. Among the 474 subjects who were evaluated at the four-week end point, the rate of resolution of middle-ear effusion was twice as high in those treated with amoxicillin, either with or without the decongestant

NEJM1987

162. Effectiveness of adenoidectomy and tympanostomy tubes in the treatment of chronic otitis media with effusion.

Effectiveness of adenoidectomy and tympanostomy tubes in the treatment of chronic otitis media with effusion. 3683478 1987 12 28 1987 12 28 2007 11 14 0028-4793 317 23 1987 Dec 03 The New England journal of medicine N. Engl. J. Med. Effectiveness of adenoidectomy and tympanostomy tubes in the treatment of chronic otitis media with effusion. 1444-51 To study the effectiveness of adenoidectomy and of the placement of tympanostomy tubes in the treatment of chronic otitis media with effusion, we (...) severely affected ear [P = 0.0174] and the number of surgical retreatments required [P = 0.009]) more than did tympanostomy tubes alone and to the same degree as did adenoidectomy and tympanostomy tubes. We conclude that adenoidectomy should be considered when surgical therapy is indicated in children four to eight years old who are severely affected by chronic otitis media with effusion. Gates G A GA Division of Otorhinolaryngology, University of Texas Health Science Center, San Antonio 78284-7777

NEJM1987

163. Lack of efficacy of a decongestant-antihistamine combination for otitis media with effusion ("secretory" otitis media) in children. Results of a double-blind, randomized trial.

Lack of efficacy of a decongestant-antihistamine combination for otitis media with effusion ("secretory" otitis media) in children. Results of a double-blind, randomized trial. 6337322 1983 03 11 1983 03 11 2013 11 21 0028-4793 308 6 1983 Feb 10 The New England journal of medicine N. Engl. J. Med. Lack of efficacy of a decongestant-antihistamine combination for otitis media with effusion ("secretory" otitis media) in children. Results of a double-blind, randomized trial. 297-301 In a double (...) -blind, randomized trial of 553 infants and children who had otitis media with effusion ("secretory" otitis media), we compared the efficacy of a four-week course of an oral decongestant-antihistamine combination (pseudoephedrine hydrochloride, 4 mg per kilogram of body weight per day, and chlorpheniramine maleate, 0.35 mg per kilogram per day) with that of placebo. Among patients with initially unilateral disease, resolution of middle-ear effusion occurred at four weeks in 38 per cent of those

NEJM1983

164. Therapy of acute otitis media: myringotomy, antibiotics, or neither? A double-blind study in children.

Therapy of acute otitis media: myringotomy, antibiotics, or neither? A double-blind study in children. 6117681 1982 01 28 1982 01 28 2015 06 16 0140-6736 2 8252 1981 Oct 24 Lancet (London, England) Lancet Therapy of acute otitis media: myringotomy, antibiotics, or neither? A double-blind study in children. 883-7 In a double-blind study 171 children with acute otitis media (239 affected ears) were treated by four different methods: neither antibiotics nor myringotomy; myringotomy only (...) and analgesics seems a reasonable initial approach to acute otitis media in children. Myringotomy and antibiotics can be reserved for cases in which the course of otitis is irregular, there are complications such as mastoiditis, or ear discharge continues beyond 14 days. van Buchem F L FL Dunk J H JH van't Hof M A MA eng Clinical Trial Comparative Study Journal Article Randomized Controlled Trial England Lancet 2985213R 0140-6736 0 Anti-Bacterial Agents AIM IM Acute Disease Anti-Bacterial Agents therapeutic

Lancet1981

165. Pneumococcal vaccine and otitis media.

Pneumococcal vaccine and otitis media. 6106735 1980 12 18 1980 12 18 2015 06 16 0140-6736 2 8194 1980 Sep 13 Lancet (London, England) Lancet Pneumococcal vaccine and otitis media. 547-51 After an acute attack of otitis media 827 children aged 3 months to 6 years were assigned randomly to receive either 14-valent pneumococcal polysaccharide vaccine or a control vaccine (Haemophilus influenzae type b capsular polysaccharide). In children older than 6 months serum antibody responses to most (...) of the vaccine polysaccharides were satisfactory. The response to type 6A was poor. Correspondingly, no clinical protection was seen below 6 months of age or against otitis media caused by group 6 pneumococci. Among the children more than 6 months old, the first 6 months after vaccination saw significantly (p < 0.001) fewer attacks caused by the pneumococal types represented in the vaccine (group 6 excepted) in those who received the pneumococcal vaccine than in those who received the control vaccine

Lancet1980

166. Persistence of middle-ear effusion after acute otitis media in children.

Persistence of middle-ear effusion after acute otitis media in children. 431635 1979 06 26 1979 06 26 2006 11 15 0028-4793 300 20 1979 May 17 The New England journal of medicine N. Engl. J. Med. Persistence of middle-ear effusion after acute otitis media in children. 1121-3 We observed the frequent occurrence of persistent middle-ear effusion in children with acute otitis media and followed them according to standard procedures for otologic diagnosis. We performed a life-table analysis (...) to identify risk factors for such persistent disease. Sixty-two patients were free of middle-ear effusion at one or more clinic visits two to 13 weeks after presentation and were considered cured; 45 had effusion at all clinic visits during this period and were defined as having persistent effusion. The life-table analysis showed that the relative risk for persistence was 3.8 times higher in children less than 24 months of age as compared with children 24 months of age or older (P less than 0.001

NEJM1979