Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4)
Latest & greatest articles for otitis media
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on otitis media or other clinical topics then use Trip today.
This page lists the very latest high quality evidence on otitis media and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.
What is Trip?
Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.
Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.
As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.
For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via firstname.lastname@example.org
Bacterial otitismedia in sub-Saharan Africa: a systematic review and meta-analysis. Otitismedia is inflammation of the middle ear, comprising a spectrum of diseases. It is the commonest episode of infection in children, which often occurs after an acute upper respiratory tract infection. Otitismedia is ranked as the second most important cause of hearing loss and the fifth global burden of disease with a higher incidence in developing worlds like Sub-Saharan Africa and South Asia. Therefore (...) , this systematic review is aimed to quantitatively estimate the current status of bacterial otitismedia, bacterial etiology and their susceptibility profile in sub-Saharan Africa.A literature search was conducted from major databases and indexing services including EMBASE (Ovid interface), PubMed/MEDLINE, Google Scholar, ScienceDirect, Cochrane Library, WHO African Index-Medicus and others. All studies (published and unpublished) addressing the prevalence of otitismedia and clinical isolates conducted in sub
Fluoroquinolones for the Treatment of OtitisMedia: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Fluoroquinolones for the Treatment of OtitisMedia: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines | CADTH.ca Find the information you need Fluoroquinolones for the Treatment of OtitisMedia: A Review of Clinical Effectiveness, Cost-Effectiveness, and Guidelines Fluoroquinolones for the Treatment of OtitisMedia: A Review of Clinical Effectiveness (...) , Cost-Effectiveness, and Guidelines Last updated: April 24, 2019 Project Number: RC1095-000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the clinical effectiveness of fluoroquinolones for the treatment of otitismedia in patients unable to take beta-lactams antibiotics? What is the cost-effectiveness of fluoroquinolones for the treatment of otitismedia in patients unable to take beta-lactams antibiotics? What are the evidence
Adverse Events of Antibiotics Used to Treat Acute OtitisMedia in Children: A Systematic Meta-Analysis. To characterize the incidence of adverse events (AEs) associated with antibiotics used to treat acute otitismedia in children.We searched MEDLINE for studies conducted between January 1, 1966, and August 25, 2018. Two authors independently assessed potential studies and extracted the data. We included published randomized controlled trials, cross-sectional studies, and cohort studies (...) that evaluated the incidence of diarrhea, generalized rash, diaper rash, and candidal diaper dermatitis associated with the use of amoxicillin, amoxicillin/clavulanate, azithromycin, cefdinir, and placebo in children with acute otitis media.We included 82 studies in the meta-analysis. The incidence of diarrhea, listed from lowest to highest, was azithromycin (2.2%), placebo (6.9%), low-dose amoxicillin (8.7%), cefdinir (13.0%), high-dose amoxicillin (13.8%), and high-dose amoxicillin/clavulanate (18.9
Efficacy of laser myringotomy compared with incisional myringotomy for the treatment of otitismedia with effusion in pediatric patients: A systematic review. Recent reports have shown that laser myringotomy (LM) is increasingly used to treat otitismedia with effusion (OME), with higher effectiveness, fewer complications, and lower recurrence rate.A systematic review of the published literature was conducted to assess the efficacy of LM compared with incisional myringotomy (IM) with or without
A systematic review and meta-analysis of antimicrobial resistance in paediatric acute otitismedia. Acute otitismedia (AOM) is the largest cause of antimicrobial prescriptions amongst children in developed countries. Excessive and inappropriate prescribing is known to drive antimicrobial resistance, but less is known of antimicrobial resistance in AOM-associated bacteria.We conducted a systematic review and meta-analysis of bacterial prevalence and antimicrobial resistance in studies
Probiotics for preventing acute otitismedia in children. Acute otitismedia (AOM), or acute middle ear infection, is one of the most frequently occurring childhood diseases, and the most common reason given for prescribing antibiotics in this age group. Guidelines often recommend antibiotics as first-line treatment for severe AOM. However, antibiotics also lead to antibiotic resistance, so preventing episodes of AOM is an urgent priority.To assess the effects of probiotics to prevent (...) the occurrence and reduce the severity of acute otitismedia in children.We searched CENTRAL, PubMed, Embase, and three other databases (October 2018), two trial registers (October 2018), and conducted a backwards and forwards citation analysis (August 2018). We did not apply any language, publication date, or publication status restrictions.Randomised controlled trials (RCTs) of children (aged up to 18 years), comparing probiotics with placebo, usual care, or no probiotic.Two review authors independently
Pneumococcal conjugate vaccines for preventing acute otitismedia in children. Prior to introducing pneumococcal conjugate vaccines (PCVs), Streptococcus pneumoniae was most commonly isolated from middle ear fluid of children with acute otitismedia (AOM). Reducing nasopharyngeal colonisation of this bacterium by PCVs may lead to a decline in AOM. The effects of PCVs deserve ongoing monitoring since studies from the post-PCV era report a shift in causative otopathogens towards non-vaccine
Inadequate harms reporting in randomized control trials of antibiotics for pediatric acute otitismedia: a systematic review. Reporting of harms in randomized control trials is often inconsistent and inadequate.To assess the quality of harms reporting in randomized control trials evaluating the efficacy of antibiotics used to treat pediatric acute otitismedia and to investigate whether connections to pharmaceutical companies or the publication of the CONSORT-Harms extension influenced (...) the quality of harms reporting.We considered randomized control trials that evaluated the efficacy and safety of antibiotic treatment for uncomplicated acute otitismedia in children aged 0-19. We evaluated the quality of harms reporting using a 19-item checklist addressing the recommendations endorsed in the CONSORT-Harms extension.160 studies met our inclusion criteria. Overall quality of reporting relating to harms was low; on average studies adhered to 55.2% of the checklist items on the quality
The unsolved problem of otitismedia in indigenous populations: a systematic review of upper respiratory and middle ear microbiology in indigenous children with otitismediaOtitismedia (OM) imposes a great burden of disease in indigenous populations around the world, despite a variety of treatment and prevention programs. Improved understanding of the pathogenesis of OM in indigenous populations is required to advance treatment and reduce prevalence. We conducted a systematic review
Oral steroids for resolution of otitismedia with effusion in children (OSTRICH): a double-blinded, placebo-controlled randomised trial. Children with persistent hearing loss due to otitismedia with effusion are commonly managed by surgical intervention. A safe, cheap, and effective medical treatment would enhance treatment options. Underpowered, poor-quality trials have found short-term benefit from oral steroids. We aimed to investigate whether a short course of oral steroids would achieve (...) acceptable hearing in children with persistent otitismedia with effusion and hearing loss.In this individually randomised, parallel, double-blinded, placebo-controlled trial we recruited children aged 2-8 years with symptoms attributable to otitismedia with effusion for at least 3 months and with confirmed bilateral hearing loss. Participants were recruited from 20 ear, nose, and throat (ENT), paediatric audiology, and audiovestibular medicine outpatient departments in England and Wales. Participants
Otitismedia Top results for otitismedia - Trip Database or use your Google+ account Find evidence fast ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4 (...) ) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for otitismedia The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you
Effectiveness of amoxicillin alone in the treatment of uncomplicated acute otitismedia: a systematic review protocol. Amoxicillin is the first-line antibiotic recommended by most scientific societies for the treatment of uncomplicated acute otitismedia (AOM) in children and adults. In low-income and middle-income countries however, absence of setting-specific recommendations and antibiotic resistance, promoted by higher population density and over-the-counter antibiotic availability, could
Middle ear irrigation using a hydrodebrider decreases biofilm surface area in an animal model of otitismedia To compare the safety and efficacy of manual and powered irrigation of the middle ear using saline or 1% baby shampoo to treat biofilm-forming bacterial middle ear infections.Biofilms play a major role in recalcitrant otitismedia and are challenging to treat. Many therapeutic strategies have been attempted and the role of topical therapies is still being investigated. Topical
Grommets (ventilation tubes) for recurrent acute otitismedia in children. Acute otitismedia (AOM) is one of the most common childhood illnesses. While many children experience sporadic AOM episodes, an important group suffer from recurrent AOM (rAOM), defined as three or more episodes in six months, or four or more in one year. In this subset of children AOM poses a true burden through frequent episodes of ear pain, general illness, sleepless nights and time lost from nursery or school (...) recurrences per child: 0.67 versus 2.17, mean difference (MD) -1.50, 95% CI -1.99 to -1.01; low-quality evidence);- number of AOM recurrences at 12 months (one study, 200 children, one-year AOM incidence rate: 1.15 versus 1.70, incidence rate difference -0.55, 95% -0.17 to -0.93; low-quality evidence).Children receiving grommets did not have better disease-specific health-related quality of life (OtitisMedia-6 questionnaire) at four (one study, 85 children) or 12 months (one study, 81 children) than
Otitismedia with effusion after radiotherapy of the head and neck: a systematic review. Otitismedia (OM) and associated hearing problems may be side effects to radiotherapy of the head and neck region and affect patient quality of life. The condition is associated with the tumor location.To perform a systematic review concerning the present knowledge of the risk of OM after radiotherapy of the head and neck.A comprehensive search of PubMed and Embase was carried out between 1 October 2015
Isolated left upper eyelid ptosis with pansinusitis and contralateral otitismedia in a 9-year-old boy Upper eyelid ptosis has different etiologies in children and adults. In children, the common causes include orbital cellulitis, congenital ptosis, Cranial Nerve (CN) III palsy, and Horner's syndrome. The purpose of this report is to discuss an unusual presentation of ptosis.We describe a case of a 9-year-old boy with left-sided ptosis with no apparent clinical signs of orbital or preseptal (...) infection. Magnetic resonance imaging (MRI) revealed pansinusitis and contralateral otitismedia with direct extension into the superior aspect of the left orbit affecting the levator palpebrae superioris muscle.This finding on imaging disclosed the etiology of an otherwise unexplained case of upper lid ptosis.
WITHDRAWN: Grommets (ventilation tubes) for recurrent acute otitismedia in children. This is an update of a Cochrane review first published in The Cochrane Library in Issue 4, 2008 and previously updated in 2011.Acute suppurative otitismedia is one of the most common infectious diseases in childhood. Recurrent acute otitismedia is defined for the purposes of this review as either three or more acute infections of the middle ear cleft in a six-month period, or at least four episodes in a year (...) . Strategies for managing the condition include the assessment and modification of risk factors where possible, repeated courses of antibiotics for each new infection, antibiotic prophylaxis and the insertion of ventilation tubes (grommets).To establish whether grommet insertion reduces the frequency of episodes of recurrent acute otitismedia and the proportion of symptomatic children.The Cochrane Ear, Nose and Throat Disorders Group (CENTDG) Trials Search Co-ordinator searched the CENTDG Trials Register
Air Pollution and OtitisMedia in Children: A Systematic Review of Literature. Young children are particularly vulnerable to otitismedia (OM) which globally affects over 80% of children below the age of 3 years. Although there is convincing evidence for an association between environmental tobacco smoke exposure and OM in children, the relationship with ambient air pollution is not clear. We aimed to systematically review the literature on the relationship between ambient air pollution