Latest & greatest articles for osteoarthritis

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Top results for osteoarthritis

161. Effect of Land-Based Generic Physical Activity Interventions on Pain, Physical Function, and Physical Performance in Hip and Knee Osteoarthritis: A Systematic Review and Meta-analysis. (Abstract)

Effect of Land-Based Generic Physical Activity Interventions on Pain, Physical Function, and Physical Performance in Hip and Knee Osteoarthritis: A Systematic Review and Meta-analysis. The aim of this study was to evaluate the effects of land-based generic physical activity interventions on pain, physical function, and physical performance in individuals with hip/knee osteoarthritis, when compared with a control group that received no intervention, minimal intervention, or usual care.A (...) to -5.17) for physical function (Western Ontario and McMaster Universities Arthritis Index) at 3 mos from randomization. Pooled estimate for walking intervention was not significant for pain intensity and physical performance but was significant for physical function (n = 2) with a MD of -10.38 (95% CI, -12.27 to -8.48) at 6 mos. Meta-analysis for conditioning exercise was significant for physical function (n = 3) with a MD of -3.74 (95% CI, -5.70 to -1.78) and physical performance (6-minute walk test

2017 American journal of physical medicine & rehabilitation

162. Efficacy and safety of aceclofenac in osteoarthritis: A meta-analysis of randomized controlled trials. Full Text available with Trip Pro

Efficacy and safety of aceclofenac in osteoarthritis: A meta-analysis of randomized controlled trials. To analyze the effects on pain, function, and safety of aceclofenac compared with other nonsteroidal anti-inflammatory drugs (NSAIDs) or pain relief medications in patients with osteoarthritis.Two investigators independently searched the database. We included randomized controlled trials evaluating efficacy and/or safety of aceclofenac compared with control interventions (NSAIDs (...) or acetaminophen) in patients with osteoarthritis. We did not include placebo, opioid analgesics, NSAID combinations, and topical analgesics for the control groups. We summarized the efficacy data as standardized mean differences (SMD) with 95% confidence intervals (CI) and safety outcomes as risk ratios (RR) with 95% CI using the inverse variance random effect model. We assessed the heterogeneity by the I2 test. We used the GRADE approach to evaluate the quality of the evidence for all outcome parameters.We

2017 European journal of rheumatology

163. Schisandrae Fructus ethanol extract ameliorates inflammatory responses and articular cartilage damage in monosodium iodoacetate-induced osteoarthritis in rats Full Text available with Trip Pro

Schisandrae Fructus ethanol extract ameliorates inflammatory responses and articular cartilage damage in monosodium iodoacetate-induced osteoarthritis in rats Schisandrae Fructus, the fruit of Schisandra chinensis (Turcz.) Baill., is widely used in traditional medicine for the treatment of a number of chronic diseases. Although, Schisandrae Fructus was recently reported to attenuate the interleukin (IL)-1β-induced inflammatory response in chondrocytes in vitro, its protective and therapeutic (...) potential against osteoarthritis (OA) in an animal model remains unclear. Therefore, we investigated the effects of the ethanol extract of Schisandrae Fructus (SF) on inflammatory responses and cartilage degradation in a monosodium iodoacetate (MIA)-induced OA rat model. Our results demonstrated that administration with SF had a tendency to attenuate MIA-induced damage of articular cartilage as determined by a histological grade of OA. SF significantly suppressed the production of pro-inflammatory

2017 EXCLI journal

164. Generating Individual Patient Preferences for the Treatment of Osteoarthritis Using Adaptive Choice-Based Conjoint (ACBC) Analysis Full Text available with Trip Pro

Generating Individual Patient Preferences for the Treatment of Osteoarthritis Using Adaptive Choice-Based Conjoint (ACBC) Analysis To explore how adaptive choice-based conjoint (ACBC) analysis could contribute to shared decision-making in the treatment of individual patients with osteoarthritis (OA).In-depth case study of three individuals randomly selected from patients with OA participating in an ACBC analysis exercise. Eleven members of a research users' group participated in developing (...) an ACBC task on medication preferences for OA. Individual medication priorities are illustrated by the detailed analysis of ACBC output from three randomly selected patients from the main sample.The case study analysis illustrates individual preferences. Participant 1's priority was avoidance of the four high-risk side effects of medication, which accounted for 90% of the importance of all attributes, while the remaining attributes (expected benefit; way of taking medication; frequency; availability

2017 Rheumatology and therapy

165. Improving Symptoms in Knee Osteoarthritis: Can We Get There From Here? Full Text available with Trip Pro

States Ann Intern Med 0372351 0003-4819 AIM IM Ann Intern Med. 2017 Apr 4;166(7):453-462 28241215 Humans Osteoarthritis, Knee 2017 2 28 6 0 2017 12 9 6 0 2017 2 28 6 0 ppublish 28241277 2605038 10.7326/M17-0330 PMC5868739 NIHMS951687 Am J Phys Med Rehabil. 2016 May;95(5):372-89 26945211 Arthritis Rheum. 2008 Sep 15;59(9):1207-13 18759314 Clin Ther. 2013 Nov;35(11):1690-702 24145044 Ann Intern Med. 2017 Apr 4;166(7):453-462 28241215 Arthritis Care Res (Hoboken). 2016 Dec;68(12 ):1743-1750 27014966 (...) Improving Symptoms in Knee Osteoarthritis: Can We Get There From Here? 28241277 2017 12 08 2018 12 02 1539-3704 166 7 2017 04 04 Annals of internal medicine Ann. Intern. Med. Improving Symptoms in Knee Osteoarthritis: Can We Get There From Here? 531-532 10.7326/M17-0330 Mandl Lisa A LA From Hospital for Special Surgery/Weill Cornell Medicine, New York, New York. eng K24 AG053462 AG NIA NIH HHS United States P30 AG022845 AG NIA NIH HHS United States Journal Article Comment 2017 02 21 United

2017 Annals of Internal Medicine

166. Scaphotrapeziotrapezoidal Joint Osteoarthritis: A Systematic Review of Surgical Treatment. (Abstract)

Scaphotrapeziotrapezoidal Joint Osteoarthritis: A Systematic Review of Surgical Treatment. The management of scaphotrapeziotrapezoidal (STT) joint osteoarthritis (OA) remains controversial. This systematic review aims to review the evidence for surgical interventions specific to STT OA.Medline and Embase libraries were searched using a pre-defined search strategy in October 2014. All study designs and languages were included and evaluated by two reviewers (VMD and LM) against the inclusion (...) algorithm for the surgical management of STT joint OA.

2017 The journal of hand surgery Asian-Pacific volume

167. Exercise for hand osteoarthritis. Full Text available with Trip Pro

Exercise for hand osteoarthritis. Hand osteoarthritis (OA) is a prevalent joint disease that may lead to pain, stiffness and problems in performing hand-related activities of daily living. Currently, no cure for OA is known, and non-pharmacological modalities are recommended as first-line care. A positive effect of exercise in hip and knee OA has been documented, but the effect of exercise on hand OA remains uncertain.To assess the benefits and harms of exercise compared with other (...) interventions, including placebo or no intervention, in people with hand OA. Main outcomes are hand pain and hand function.We searched six electronic databases up until September 2015.All randomised and controlled clinical trials comparing therapeutic exercise versus no exercise or comparing different exercise programmes.Two review authors independently selected trials, extracted data, assessed risk of bias and assessed the quality of the body of evidence using the GRADE approach. Outcomes consisted of both

2017 Cochrane

168. Patient, Provider, and Combined Interventions for Managing Osteoarthritis in Primary Care: A Cluster Randomized Trial. Full Text available with Trip Pro

for osteoarthritis in a Department of Veterans Affairs medical center, this study found no statistically significant improvements in the osteoarthritis intervention groups compared with usual care.National Institute of Arthritis and Musculoskeletal and Skin Diseases. (...) Patient, Provider, and Combined Interventions for Managing Osteoarthritis in Primary Care: A Cluster Randomized Trial. A single-site study showed that a combined patient and provider intervention improved outcomes for patients with knee osteoarthritis, but it did not assess separate effects of the interventions.To examine whether patient-based, provider-based, and patient-provider interventions improve osteoarthritis outcomes.Cluster randomized trial with assignment to patient, provider

2017 Annals of Internal Medicine Controlled trial quality: predicted high

169. Clinical Practice Guideline on the Management of Osteoarthritis of the Hip

will benefit from specific treatment options. This guideline is not intended for use as a benefits determination document. PATIENT POPULATION This document addresses the management osteoarthritis of the hip in adult patients defined as those 18 years of age and older. It is not intended to address management of pediatric patients with osteoarthritis or patients with inflammatory arthritis or osteonecrosis of the hip. BURDEN OF DISEASE The burden of osteoarthritis (OA) of the hip is largely attributable (...) to the effects of disability, comorbid disease, and the expense of treatment. OA is the most frequent cause of disability among adults in the United States (US), and the burden is increasing both as the prevalence of OA increases and also as patient expectations for treatment rise. Twenty seven million adults (more than 10 percent) of the US adult population had clinical osteoarthritis (OA) in 2005, and in 2009 OA was the fourth most common cause of hospitalization (Murphy & Helmick, 2012). OA is the leading

2017 American Academy of Orthopaedic Surgeons

170. Arthroscopic surgery for degenerative knee arthritis and meniscal tears

Including people with or without: Mild to severe osteoarthritis Radiographic evidence of osteoarthritis i X-ray or MRI changes of arthritis Mechanical symptoms i Locking, clicking, catching Acute onset knee pain i Pain started suddenly or slowly Meniscal tears i Tear in knee cartilage People with degenerative knee disease Choice of intervention or Arthroscopic surgery Conservative management Any conservative management strategy (exercise therapy, injections, drugs) Arthroscopic surgery with or without (...) ? Degenerative knee disease is an inclusive term, which many consider synonymous with osteoarthritis. We use the term degenerative knee disease to explicitly include patients with knee pain, particularly if they are >35 years old, with or without: Imaging evidence of osteoarthritis Meniscus tears Locking, clicking, or other mechanical symptoms except persistent objective locked knee Acute or subacute onset of symptoms Most people with degenerative arthritis have at least one of these characteristics

2017 BMJ Rapid Recommendations

171. In adults with ankle osteoarthritis (OA), is total ankle replacement/fusion/debridement better than no treatment for pain and function, risks and harms and adverse events?

(In the final document this should be a combination of your clinical and librarian search terms) Population and Setting Adults with ankle OA Adults, ankle OA, ankle osteoarthritis, degenerative changes Getting Evidence into Clinical Practice: Musculoskeletal Research Facilitation Group (CAT Group) Date: February 2018 CAT Lead: Jo Pike Date CAT completed: February 2018 joannapike@nhs.net Date CAT to be reviewed: February 2021 Intervention or Exposure Surgical intervention in the form of either joint sparing (...) In adults with ankle osteoarthritis (OA), is total ankle replacement/fusion/debridement better than no treatment for pain and function, risks and harms and adverse events? Getting Evidence into Clinical Practice: Musculoskeletal Research Facilitation Group (CAT Group) Date: February 2018 CAT Lead: Jo Pike Date CAT completed: February 2018 joannapike@nhs.net Date CAT to be reviewed: February 2021 Specific Question: In adults with ankle Osteoarthritis (OA) A is total ankle replacement/fusion

2017 Public Health England

172. In adults with ankle osteoarthritis is exercise/physiotherapy/rehabilitation/conservative treatment more effective than surgical options?

trials have been completed. Why is this important? This question was selected due to the lack of standardisation by clinicians with regards to best clinical practice. Ankle OA constitutes only 4.4% of patients referred to orthopedic clinic for the management of lower extremity OA. Search timeframe (e.g. 2006-2017) Inclusion Criteria Description Search terms Population and Setting Adults with ankle OA within any care setting Adults, OA, osteoarthritis, lower limb, talocrural joint, joint pain (...) In adults with ankle osteoarthritis is exercise/physiotherapy/rehabilitation/conservative treatment more effective than surgical options? Getting Evidence into Clinical Practice: Musculoskeletal Research Facilitation Group (CAT Group) Date: September 2017 CAT Lead: Ben Lannie Date CAT completed: August 2017 Email: maddocksclinic@btconnect.com Date CAT to be reviewed: September 2020 Specific Question: In adults with ankle osteoarthritis is exercise / physiotherapy / rehabilitation / conservative

2017 Public Health England

179. Comparative effectiveness review of platelet-rich plasma for knee osteoarthritis: a review of reviews

HAYES, Inc. Comparative effectiveness review of platelet-rich plasma for knee osteoarthritis: a review of reviews. Lansdale: HAYES, Inc. Directory Publication. 2017 Authors' conclusions Health Problem: Osteoarthritis (OA) is a painful condition in which the cartilage between the bones degenerates, no longer providing a smooth, gliding surface for motion or adequate cushioning. Because OA damages the cartilage and may ultimately damage the bone, it disrupts how components work together, resulting (...) with PRP for knee OA, and how do complications compare with sham injection and other IA treatments? Have definitive patient selection criteria been established for PRP for knee OA? Final publication URL The report may be purchased from: Indexing Status Subject indexing assigned by CRD MeSH Humans; Osteoarthritis, Knee; Platelet-Rich Plasma Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence HAYES, Inc

2017 Health Technology Assessment (HTA) Database.

180. Comparative effectiveness review of hyaluronic acid for knee osteoarthritis: a review of reviews

. Comparative effectiveness review of hyaluronic acid for knee osteoarthritis: a review of reviews. Lansdale: HAYES, Inc. Directory Publication. 2017 Authors' conclusions Health Problem: Osteoarthritis (OA) is a painful condition in which the cartilage between the bones degenerates, no longer providing a smooth, gliding surface for motion or adequate cushioning. Because OA damages the cartilage and may ultimately damage the bone, it disrupts how components work together, resulting in pain, swelling (...) , inflammation, muscle weakness, impaired quality of life (QOL), and reduced function. The knee is commonly afflicted by OA. Technology Description: Hyaluronic acid (HA) is a component of synovial fluid, which lubricates the joint and absorbs shock. HA production is generally reduced and may be of poorer quality in patients with OA, which may exacerbate inflammation. Intra-articular (IA) injection of HA (IA-HA) aims to replace depleted or poor-quality HA in the joint. Controversy: Despite a large evidence

2017 Health Technology Assessment (HTA) Database.