Latest & greatest articles for osteoarthritis

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Top results for osteoarthritis

81. Pathogenesis and management of pain in osteoarthritis.

Pathogenesis and management of pain in osteoarthritis. The term osteoarthritis describes a common, age-related, heterogeneous group of disorders characterised pathologically by focal areas of loss of articular cartilage in synovial joints, associated with varying degrees of osteophyte formation, subchondral bone change, and synovitis. Joint damage is caused by a mixture of systemic factors that predispose to the disease, and local mechanical factors that dictate its distribution and severity (...) . Various genetic abnormalities have been described, but most sporadic osteoarthritis probably depends on minor contributions from several genetic loci. Osteoarthritic joint damage may be associated with clinical problems, but the severity of joint disease is only weakly related to that of the clinical problem. For this reason the associations and pathogenesis of pain are in as much need of investigation as joint damage. Subchondral bone and synovium may be responsible for nociceptive stimuli

Lancet2017

83. A Prospective Randomized Trial of Prognostic Genicular Nerve Blocks to Determine the Predictive Value for the Outcome of Cooled Radiofrequency Ablation for Chronic Knee Pain Due to Osteoarthritis

A Prospective Randomized Trial of Prognostic Genicular Nerve Blocks to Determine the Predictive Value for the Outcome of Cooled Radiofrequency Ablation for Chronic Knee Pain Due to Osteoarthritis 29300971 2018 03 08 1526-4637 2017 Dec 28 Pain medicine (Malden, Mass.) Pain Med A Prospective Randomized Trial of Prognostic Genicular Nerve Blocks to Determine the Predictive Value for the Outcome of Cooled Radiofrequency Ablation for Chronic Knee Pain Due to Osteoarthritis. 10.1093/pm/pnx286 (...) Genicular nerve radiofrequency ablation is an effective treatment for patients with chronic pain due to knee osteoarthritis; however, little is known about factors that predict procedure success. The current study evaluated the utility of genicular nerve blocks to predict the outcome of genicular nerve cooled radiofrequency ablation (cRFA) in patients with osteoarthritis. This randomized comparative trial included patients with chronic knee pain due to osteoarthritis. Participants were randomized

EvidenceUpdates2017

84. Comparative effectiveness review of platelet-rich plasma for knee osteoarthritis: a review of reviews

Comparative effectiveness review of platelet-rich plasma for knee osteoarthritis: a review of reviews Comparative effectiveness review of platelet-rich plasma for knee osteoarthritis: a review of reviews Comparative effectiveness review of platelet-rich plasma for knee osteoarthritis: a review of reviews HAYES, Inc Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation (...) HAYES, Inc. Comparative effectiveness review of platelet-rich plasma for knee osteoarthritis: a review of reviews. Lansdale: HAYES, Inc. Directory Publication. 2017 Authors' conclusions Health Problem: Osteoarthritis (OA) is a painful condition in which the cartilage between the bones degenerates, no longer providing a smooth, gliding surface for motion or adequate cushioning. Because OA damages the cartilage and may ultimately damage the bone, it disrupts how components work together, resulting

Health Technology Assessment (HTA) Database.2017

85. Comparative effectiveness review of hyaluronic acid for knee osteoarthritis: a review of reviews

Comparative effectiveness review of hyaluronic acid for knee osteoarthritis: a review of reviews Comparative effectiveness review of hyaluronic acid for knee osteoarthritis: a review of reviews Comparative effectiveness review of hyaluronic acid for knee osteoarthritis: a review of reviews HAYES, Inc Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation HAYES, Inc (...) . Comparative effectiveness review of hyaluronic acid for knee osteoarthritis: a review of reviews. Lansdale: HAYES, Inc. Directory Publication. 2017 Authors' conclusions Health Problem: Osteoarthritis (OA) is a painful condition in which the cartilage between the bones degenerates, no longer providing a smooth, gliding surface for motion or adequate cushioning. Because OA damages the cartilage and may ultimately damage the bone, it disrupts how components work together, resulting in pain, swelling

Health Technology Assessment (HTA) Database.2017

87. Treatments to reduce the need for surgical intervention in people with osteoarthritis

Treatments to reduce the need for surgical intervention in people with osteoarthritis Treatments to reduce the need for surgical intervention in people with osteoarthritis - NIPH Selected items added to basket Close Vis søkefelt How can we help you today? Search for: Søk Menu • • Treatments to reduce the need for surgical intervention in people with osteoarthritis Søk i Folkehelsa.no Search for: Søk Infectious diseases & Vaccines Close Mental & Physical health Close Environment & Lifestyle (...) Close Health in Norway Close Quality & Knowledge Close Research & Access to data Close Key message Norwegian Knowledge Centre for the Health Services has been commissioned by the Norwegian Rheumatism Association to search for research on the effects of various treatments on need for surgical interventions in people with osteoarthritis. Methods On 28 April 2010, we searched for relevant systematic reviews in The Cochrane Library, MEDLINE, EMBASE, PsycINFO, Centre for Reviews and Dissemination (CRD

The Norwegian Knowledge Centre for the Health Services2017

94. Intra-articular Corticosteroids for Osteoarthritis of the Knee.

Intra-articular Corticosteroids for Osteoarthritis of the Knee. Clinical Question: Are intra-articular corticosteroids associated with improvement in pain and physical function compared with sham injection or no intervention in patients with knee osteoarthritis? Bottom Line: Intra-articular corticosteroids may be associated with moderate improvement in pain and a small improvement in physical function up to 6 weeks after injection. However, the quality of the evidence is low.

JAMA2016

95. Predictive capacity of thigh muscle strength in symptomatic and/or radiographic knee osteoarthritis progression – data from the FNIH OA Biomarkers Consortium

Predictive capacity of thigh muscle strength in symptomatic and/or radiographic knee osteoarthritis progression – data from the FNIH OA Biomarkers Consortium 27175558 2017 07 17 2018 11 13 1537-7385 95 12 2016 12 American journal of physical medicine & rehabilitation Am J Phys Med Rehabil Predictive Capacity of Thigh Muscle Strength in Symptomatic and/or Radiographic Knee Osteoarthritis Progression: Data from the Foundation for the National Institutes of Health Osteoarthritis Biomarkers (...) Consortium. 931-938 Thigh muscle weakness is a risk factor for incident radiographic and symptomatic knee osteoarthritis (KOA). The role of thigh muscle weakness in radiographic and/or symptomatic KOA progression remains elusive. Five hundred twenty-seven knees of 527 Osteoarthritis Initiative participants with baseline Kellgren-Lawrence grades 1 to 3 were included in this nested case-control study evaluating whether baseline muscle strength predicted symptomatic and/or radiographic KOA progression. Case

American journal of physical medicine & rehabilitation2016 Full Text: Link to full Text with Trip Pro

96. Hyaluronic acid injection therapy for osteoarthritis of the knee: concordant efficacy and conflicting serious adverse events in two systematic reviews.

Hyaluronic acid injection therapy for osteoarthritis of the knee: concordant efficacy and conflicting serious adverse events in two systematic reviews. BACKGROUND: The prevalence of knee osteoarthritis (OA)/degenerative joint disease (DJD) is increasing in the USA. Systematic reviews of treatment efficacy and adverse events (AEs) of hyaluronic acid (HA) injections report conflicting evidence about the balance of benefits and harms. We review evidence on efficacy and AEs of intraarticular (...) viscosupplementation with HA in older individuals with knee osteoarthritis and account for differences in these conclusions from another systematic review. METHODS: We searched PubMed and eight other databases and gray literature sources from 1990 to December 12, 2014. Double-blind placebo-controlled randomized controlled trials (RCTs) reporting functional outcomes or quality-of-life; RCTs and observational studies on delay/avoidance of arthroplasty; RCTs, case reports, and large cohort studies and case series

Systematic Reviews2016 Full Text: Link to full Text with Trip Pro

97. Intra-Articular Cellular Therapy for Osteoarthritis and Focal Cartilage Defects of the Knee: A Systematic Review of the Literature and Study Quality Analysis

Intra-Articular Cellular Therapy for Osteoarthritis and Focal Cartilage Defects of the Knee: A Systematic Review of the Literature and Study Quality Analysis 27655978 2016 09 22 2017 03 23 2017 03 23 1535-1386 98 18 2016 Sep 21 The Journal of bone and joint surgery. American volume J Bone Joint Surg Am Intra-Articular Cellular Therapy for Osteoarthritis and Focal Cartilage Defects of the Knee: A Systematic Review of the Literature and Study Quality Analysis. 1511-21 10.2106/JBJS.15.01495 Intra (...) -articular cellular therapy injections constitute an appealing strategy that may modify the intra-articular milieu or regenerate cartilage in the settings of osteoarthritis and focal cartilage defects. However, little consensus exists regarding the indications for cellular therapies, optimal cell sources, methods of preparation and delivery, or means by which outcomes should be reported. We present a systematic review of the current literature regarding the safety and efficacy of cellular therapy

EvidenceUpdates2016

98. The Effects of Acupuncture on Chronic Knee Pain Due to Osteoarthritis: A Meta-Analysis

The Effects of Acupuncture on Chronic Knee Pain Due to Osteoarthritis: A Meta-Analysis 27655986 2016 09 22 2017 03 23 2017 03 23 1535-1386 98 18 2016 Sep 21 The Journal of bone and joint surgery. American volume J Bone Joint Surg Am The Effects of Acupuncture on Chronic Knee Pain Due to Osteoarthritis: A Meta-Analysis. 1578-85 10.2106/JBJS.15.00620 Acupuncture reportedly relieves chronic knee pain and improves physical function in patients diagnosed with osteoarthritis, but the duration (...) of these effects is controversial. The aim of this study was to evaluate the temporal effects of acupuncture on chronic knee pain due to knee osteoarthritis by means of a meta-analysis. The PubMed, Embase, and Cochrane Central Register of Controlled Trials databases were searched for studies published through March 2015. Ten randomized controlled trials of acupuncture compared with sham acupuncture, usual care, or no intervention for chronic knee pain in patients with clinically diagnosed or radiographically

EvidenceUpdates2016

99. Efficacy of Cabbage Leaf Wraps in the Treatment of Symptomatic Osteoarthritis of the Knee: A Randomized Controlled Trial

Efficacy of Cabbage Leaf Wraps in the Treatment of Symptomatic Osteoarthritis of the Knee: A Randomized Controlled Trial 26889617 2016 02 18 2016 10 18 1536-5409 32 11 2016 Nov The Clinical journal of pain Clin J Pain Efficacy of Cabbage Leaf Wraps in the Treatment of Symptomatic Osteoarthritis of the Knee: A Randomized Controlled Trial. 961-971 Osteoarthritis (OA) of the knee is one of the most common chronic diseases among older adults. This study aimed to test the effects of cabbage leaf (...) wraps (CLWs) in the treatment of symptomatic OA. Patients with OA of the knee at stages II to III (Kellgren-Lawrence) were randomly assigned to 4 weeks of treatment with CLWs (daily for at least 2h), topical pain gel (TPG) (10 mg diclofenac/g, at least once daily), or usual care (UC). The primary outcome measure was pain intensity (VAS) after 4 weeks. Secondary outcomes included functional disability Western Ontario and McMaster Universities Arthritis Index (WOMAC), quality of life (SF-36), self

EvidenceUpdates2016

100. Anxiety and depression in patients with osteoarthritis: impact and management challenges

Anxiety and depression in patients with osteoarthritis: impact and management challenges © 2016 Sharma et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms. php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted (...) Article http://dx.doi.org/10.2147/OARRR.S93516 Anxiety and depression in patients with osteoarthritis: impact and management challenges Anirudh sharma 1 Prtha Kudesia 2 Qian shi 2 Rajiv gandhi 2 1 Division of genetics and Development, Krembil Research institute, 2 Division of Orthopaedic surgery, T oronto Western hospital, Toronto, On , canada Background: Anxiety and depression are common psychological comorbidities that impact the quality of life (QoL) of patients. In this systematic review, we 1

Open access rheumatology : research and reviews2016 Full Text: Link to full Text with Trip Pro