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Latest & greatest articles for osteoarthritis
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on osteoarthritis or other clinical topics then use Trip today.
This page lists the very latest high quality evidence on osteoarthritis and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.
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A cost-effectiveness analysis of total hip arthroplasty for osteoarthritis of the hip A cost-effectiveness analysis of total hip arthroplasty for osteoarthritis of the hip A cost-effectiveness analysis of total hip arthroplasty for osteoarthritis of the hip Chang R W, Pellissier J M, Hazen G B Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions (...) followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Total hip arthroplasty (THA) for the osteoarthritis of the hip. Type of intervention Elective treatment. Economic study type Cost-effectiveness analysis. Study population Persons with functionally significant hip osteoarthritis. Setting Hospital. The economic study was conducted in Chicago, USA. Dates to which data relate Effectiveness data related to studies published after 1986
The efficacy of aerobic exercises for treating osteoarthritis of the knee The efficacy of aerobic exercises for treating osteoarthritis of the knee The efficacy of aerobic exercises for treating osteoarthritis of the knee La Mantia K, Marks R Authors' objectives To critically examine the efficacy of aerobic exercise for treating osteoarthritis of the knee. Searching MEDLINE was searched from 1985 to 94 with search terms (explode) 'arthritis', (explode) 'osteoarthritis', 'exercise', (explode (...) ) 'exercise therapy', 'randomised controlled trial', and 'review articles'; CINAHL was searched from 1980 to 1994 using the search terms (explode) 'arthritis', (explode) 'exercise', (explode) 'osteoarthritis' and 'aerobic exercises'. Other sources of information were handsearched, and experts were contacted for additional material. Only article published in the English language and describing studies in humans were considered. Study selection Study designs of evaluations included in the review Prospective
Published trials of nonmedicinal and noninvasive therapies for hip and knee osteoarthritis Published trials of nonmedicinal and noninvasive therapies for hip and knee osteoarthritis Published trials of nonmedicinal and noninvasive therapies for hip and knee osteoarthritis Puett D W, Griffin M R Authors' objectives To review the efficacy of nonmedicinal, noninvasive therapies in knee and hip osteoarthritis. Searching MEDLINE was searched from 1966 to 1993 by cross-referencing the medical therapy (...) subheadings of 'osteoarthritis' (including 'drug therapy', 'radiotherapy', 'surgery' and 'rehabilitation') with 'clinical trials', 'comparative study' or 'trial(s)'. Bibliographies of articles meeting the inclusion criteria were examined. English language articles were retrieved. Study selection Study designs of evaluations included in the review Controlled trials in which patients were assigned to either (1) a treatment group consisting of nonmedicinal, noninvasive therapy, or (2) a concurrent control
Nabumetone in elderly patients with osteoarthritis: economic benefits versus ibuprofen alone or ibuprofen plus misoprostol Nabumetone in elderly patients with osteoarthritis: economic benefits versus ibuprofen alone or ibuprofen plus misoprostol Nabumetone in elderly patients with osteoarthritis: economic benefits versus ibuprofen alone or ibuprofen plus misoprostol Bentkover J D, Baker A M, Kaplam H Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) type Cost-effectiveness analysis Study population Elderly patients (> 60 years of age) with osteoarthritis. Setting Primary care. The economic study was carried out in the USA. Dates to which data relate Cost data was calculated for 1992 US dollars, and effectiveness data was gathered from a trial conducted in 1993. Source of effectiveness data The evidence for effectiveness was derived from a single study. Link between effectiveness and cost data Cost data was not collected on patients included
Taping the patella medially: a new treatment for osteoarthritis of the knee joint? To test the hypothesis that medial taping of the patella reduces the symptoms of osteoarthritis of the knee when the patellofemoral joint is affected.Randomised, single blind, crossover trial of three different forms of taping of the knee joint. Each tape (medial, lateral, or neutral) was applied for four days, with three days of no treatment between tape positions.14 patients with established, symptomatic (...) osteoarthritis of the knee and both clinical and radiographic evidence of patellofemoral compartment disease.Daily visual analogue scale ratings for pain; patients' rating of change with each treatment; and tape preference.Medial taping of the patella was significantly better than the neutral or lateral taping for pain scores, symptom change, and patient preference. The medial tape resulted in a 25% reduction in knee pain.Patella taping is a simple, safe, cheap way of providing short term pain relief
n of 1 trials comparing a non-steroidal anti-inflammatory drug with paracetamol in osteoarthritis. To evaluate the efficacy of paracetamol and a non-steroidal anti-inflammatory drug for symptom relief in osteoarthritis.Double blind, randomised, controlled trials in individual patients (n of 1 trials). Three treatment cycles with two weeks' each of paracetamol (1 g twice daily) and diclofenac (50 mg twice daily) prepared in identical gelatin capsules.General practices in metropolitan Sydney (...) , Australia.25 patients (median age 64 years) with pain of osteoarthritis (median duration of disease eight years) considered by their general practitioners to require regular treatment. 20 were already taking non-steroidal anti-inflammatory drugs.Diary of pain and stiffness, function, and side effects.15 patients completed the study, five withdrew early but had made a therapeutic decision, and five dropped out very early. Results from 20 patients were analysed. Several patterns of response evolved. Eight
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee. The optimal short-term, symptomatic therapy for osteoarthritis of the knee has not been fully determined. Accordingly, we compared the efficacy of a nonsteroidal antiinflammatory drug, ibuprofen, given in either an antiinflammatory dose (high dose) or an analgesic dose (low dose), with that of acetaminophen, a pure analgesic.In (...) a randomized, double-blind trial, 184 patients with chronic knee pain due to osteoarthritis were given either 2400 or 1200 mg of ibuprofen per day or 4000 mg of acetaminophen per day. They were evaluated after a washout period of three to seven days before the beginning of the study, and again after four weeks of treatment. The major measures of outcome included scores on the pain and disability scales of the Stanford Health Assessment Questionnaire (range of possible scores, 0 to 3), scores on the visual
Effect of non-steroidal anti-inflammatory drugs on the course of osteoarthritis. To test the hypothesis that non-steroidal anti-inflammatory drugs (NSAIDs) accelerate the progression of osteoarthritis by reducing synthesis of vasodilator prostaglandins, thereby diminishing joint perfusion, 105 osteoarthritis patients awaiting hip arthroplasty were treated prospectively with a strong or weak prostaglandin synthesis inhibitor, indomethacin or azapropazone, respectively. Pain and radiological (...) concentrations of synovial vasodilator prostaglandins, took longer than the indomethacin group to reach the arthroplasty end-point. Potent inhibitors of prostaglandin synthesis may be inappropriate in the management of osteoarthritis of the hip.
Controlled trial of homoeopathic treatment of osteoarthritis. In a double-blind, placebo-controlled crossover study to compare the homoeopathic remedy Rhus tox. 6X with fenoprofen in osteoarthritis of the hip and knee, fenoprofen was shown to have beneficial analgesic and anti-inflammatory effects which differed significantly from those of placebo. The effects of Rhus tox. 6X and placebo did not differ significantly. Patient preference was for fenoprofen. Side-effects were not severe but were
Trolamine salicylate cream in osteoarthritis of the knee. Twenty-five patients with symptomatic osteoarthritis (OA) of the knee were treated topically for one week with either 10% trolamine salicylate cream or placebo cream in a randomized double-blind crossover study. No significant difference was found in subjective or objective measures of pain relief between the treatment and control groups. Eight patients preferred "active" test cream, six preferred placebo, and 11 had no preference