Latest & greatest articles for osteoarthritis

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on osteoarthritis or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on osteoarthritis and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

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Top results for osteoarthritis

21. Osteoarthritis

Osteoarthritis Top results for osteoarthritis - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing (...) the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for osteoarthritis The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines

Trip Latest and Greatest2018

22. Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials

Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials Journals Library An error occurred retrieving content to display, please (...) try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> {{metadata.Title}} {{metadata.Headline}} The programme provides evidence for primary care for patients with osteoarthritis, but against enhancing current physical activity interventions (BEEP RCT) or including routine screening

NIHR HTA programme2018

23. 2018 EULAR recommendations for physical activity in people with inflammatory arthritis and osteoarthritis

2018 EULAR recommendations for physical activity in people with inflammatory arthritis and osteoarthritis 29997112 2018 08 11 1468-2060 77 9 2018 Sep Annals of the rheumatic diseases Ann. Rheum. Dis. 2018 EULAR recommendations for physical activity in people with inflammatory arthritis and osteoarthritis. 1251-1260 10.1136/annrheumdis-2018-213585 Regular physical activity (PA) is increasingly promoted for people with rheumatic and musculoskeletal diseases as well as the general population. We (...) evaluated if the public health recommendations for PA are applicable for people with inflammatory arthritis (iA; Rheumatoid Arthritis and Spondyloarthritis) and osteoarthritis (hip/knee OA) in order to develop evidence-based recommendations for advice and guidance on PA in clinical practice. The EULAR standardised operating procedures for the development of recommendations were followed. A task force (TF) (including rheumatologists, other medical specialists and physicians, health professionals, patient

EvidenceUpdates2018

24. Osteoarthritis

Osteoarthritis Autosynthesis - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button

Trip Evidence Maps2018

25. Knee osteoarthritis in professional football is related to severe knee injury and knee surgery

Knee osteoarthritis in professional football is related to severe knee injury and knee surgery 29911282 2018 11 14 2197-1714 5 1 2018 Jun 18 Injury epidemiology Inj Epidemiol Knee osteoarthritis in professional football is related to severe knee injury and knee surgery. 26 10.1186/s40621-018-0157-8 As a consequence of severe knee injuries, knee osteoarthritis (OA) seems prevalent in retired professional footballers. However, some epidemiological data remain missing, for instance whether knee OA (...) is also prevalent in current professional footballers, whether knee OA is associated with knee injuries and surgeries, and whether knee OA leads to a lower level of functioning. Therefore, three research questions were answered: (i) what is the prevalence of knee osteoarthritis (OA) among current and retired professional footballers? (ii) is severe knee injury or knee surgery associated with knee OA among current and retired professional footballers? (iii) what are the consequences of knee OA on

Injury epidemiology2018 Full Text: Link to full Text with Trip Pro

26. MMP-3 in the peripheral serum as a biomarker of knee osteoarthritis, 40 years after open total knee meniscectomy

MMP-3 in the peripheral serum as a biomarker of knee osteoarthritis, 40 years after open total knee meniscectomy 29904905 2018 11 14 2197-1153 5 1 2018 Jun 15 Journal of experimental orthopaedics J Exp Orthop MMP-3 in the peripheral serum as a biomarker of knee osteoarthritis, 40 years after open total knee meniscectomy. 21 10.1186/s40634-018-0132-x To explore potential biomarkers in a meniscectomy-induced knee osteoarthritis model, at forty years after meniscectomy. We carried out a forty (...) and peripheral serum was measured using Alcian blue precipitation and ELISA quantification, respectively. Patients also had their knee radiographs assessed and their radiographic osteoarthritis classified as per the Kellgren-Lawrence and Ahlbӓck systems. At forty years after meniscectomy, synovial MMP-3 levels remain increased (p = 0.0132) while GAG levels were reduced (p = 0.0487) when compared to controls and these two levels correlate inversely. Furthermore, levels of synovial MMP-3 significantly

Journal of experimental orthopaedics2018 Full Text: Link to full Text with Trip Pro

27. The effect of 12-week garlic supplementation on symptom relief in overweight or obese women with knee osteoarthritis

The effect of 12-week garlic supplementation on symptom relief in overweight or obese women with knee osteoarthritis 29790635 2018 05 23 1742-1241 2018 May 23 International journal of clinical practice Int. J. Clin. Pract. The effect of 12-week garlic supplementation on symptom relief in overweight or obese women with knee osteoarthritis. e13208 10.1111/ijcp.13208 Chronic joint pain and stiffness, and functional disability, are the major debilitating features of osteoarthritis (OA). The aim (...) of this study was to assess the effect of 12-week supplementation with a garlic supplement on knee osteoarthritis outcomes in overweight or obese women. Seventy-six postmenopausal overweight or obese women (25≤BMI≤40 kg/m 2 ) with medically diagnosed knee OA participated in this randomised double-blind, placebo-controlled, parallel-design trial. After randomisation into 2 groups, patients received a daily dose of either 1000 mg odourless garlic tablet, or placebo, for 12 weeks. The total Western Ontario

EvidenceUpdates2018

28. Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo-Controlled, Multinational Study

Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo-Controlled, Multinational Study 29664853 2018 06 15 1535-1386 100 8 2018 Apr 18 The Journal of bone and joint surgery. American volume J Bone Joint Surg Am Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo (...) -Controlled, Multinational Study. 666-677 10.2106/JBJS.17.00154 Intra-articular corticosteroids relieve osteoarthritis pain, but rapid systemic absorption limits efficacy. FX006, a novel, microsphere-based, extended-release triamcinolone acetonide (TA) formulation, prolongs TA joint residence and reduces systemic exposure compared with standard TA crystalline suspension (TAcs). We assessed symptomatic benefits and safety of FX006 compared with saline-solution placebo and TAcs. In this Phase-3, multicenter

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

29. Systematic clinical evidence review of NASHA (Durolane hyaluronic acid) for the treatment of knee osteoarthritis

Systematic clinical evidence review of NASHA (Durolane hyaluronic acid) for the treatment of knee osteoarthritis 29849470 2018 11 14 1179-156X 10 2018 Open access rheumatology : research and reviews Open Access Rheumatol Systematic clinical evidence review of NASHA (Durolane hyaluronic acid) for the treatment of knee osteoarthritis. 43-54 10.2147/OARRR.S162127 Pain and limitations in joint mobility associated with knee osteoarthritis (OA) are clinically challenging to manage, and advanced (...) progression of disease can often lead to total knee arthroplasty. Intra-articular injection of hyaluronic acid (HA), also referred to as viscosupplementation, is a non-surgical treatment approach for OA, the effectiveness of which may depend on the HA composition, and the length of time over which it resides in the joint. One of the available options for such therapies includes NASHA (Durolane HA), a non-animal, biofermentation-derived product, which is manufactured using a process that stabilizes the HA

Open access rheumatology : research and reviews2018 Full Text: Link to full Text with Trip Pro

30. Exercise Therapy Interventions in Patients With Hip Osteoarthritis: Comparison of the Effects of DVD and Website-Based Interventions

Exercise Therapy Interventions in Patients With Hip Osteoarthritis: Comparison of the Effects of DVD and Website-Based Interventions 29735473 2018 11 14 2369-2529 5 1 2018 May 07 JMIR rehabilitation and assistive technologies JMIR Rehabil Assist Technol Exercise Therapy Interventions in Patients With Hip Osteoarthritis: Comparison of the Effects of DVD and Website-Based Interventions. e10 10.2196/rehab.8251 Prevalence of developmental hip dysplasia is high in Japan. Exercise therapy has been (...) proven effective to treat certain aspects of hip osteoarthritis. Moreover, therapy provided via digital video discs (DVDs) and websites allows patients to exercise in the comfort of their own homes. However, no studies have evaluated the effectiveness of visual instructions in patients with hip disorders. This study aimed to compare the effectiveness of exercise therapy administered via DVD and that administered via a website. We developed a six-step progressive exercise therapy program for patients

JMIR rehabilitation and assistive technologies2018 Full Text: Link to full Text with Trip Pro

31. Acupuncture for hip osteoarthritis.

Acupuncture for hip osteoarthritis. BACKGROUND: Hip osteoarthritis (OA) is a major cause of pain and functional limitation. Few hip OA treatments have been evaluated for safety and effectiveness. Acupuncture is a traditional Chinese medical therapy which aims to treat disease by inserting very thin needles at specific points on the body. OBJECTIVES: To assess the benefits and harms of acupuncture in patients with hip OA. SEARCH METHODS: We searched Cochrane CENTRAL, MEDLINE, and Embase all (...) participants were included. Four RCTs included only people with OA of the hip, and two included a mix of people with OA of the hip and knee. All RCTs included primarily older participants, with a mean age range from 61 to 67 years, and a mean duration of hip OA pain from two to eight years. Approximately two-thirds of participants were women. Two RCTs compared acupuncture versus sham acupuncture; the other four RCTs were not blinded. All results were evaluated at short term (i.e. four to nine weeks after

Cochrane2018

32. Effectiveness of aquatic exercises compared to patient-education on health status in individuals with knee osteoarthritis: a randomized controlled trial

Effectiveness of aquatic exercises compared to patient-education on health status in individuals with knee osteoarthritis: a randomized controlled trial 29417831 2018 02 21 1477-0873 2018 Feb 01 Clinical rehabilitation Clin Rehabil Effectiveness of aquatic exercises compared to patient-education on health status in individuals with knee osteoarthritis: a randomized controlled trial. 269215517754240 10.1177/0269215517754240 To compare the effectiveness of aquatic exercises with patient-education (...) in individuals with knee osteoarthritis. Randomized controlled trial with blinded assessor and intention-to-treat analysis. Aquatic Physiotherapy Centre and Primary Health Care Unit. A total of 60 patients, aged 68.3 (SD = 4.8) with clinical symptoms and radiographic grading (Kellgren-Lawrence 1-4) of knee osteoarthritis were included. An eight-week treatment protocol of aquatic exercise ( n = 31) (16 individual sessions, twice a week) and an educational program (group sessions, once a week) ( n = 29

EvidenceUpdates2018

33. EULAR recommendations for the health professional's approach to pain management in inflammatory arthritis and osteoarthritis

EULAR recommendations for the health professional's approach to pain management in inflammatory arthritis and osteoarthritis 29724726 2018 05 11 1468-2060 77 6 2018 Jun Annals of the rheumatic diseases Ann. Rheum. Dis. EULAR recommendations for the health professional's approach to pain management in inflammatory arthritis and osteoarthritis. 797-807 10.1136/annrheumdis-2017-212662 Pain is the predominant symptom for people with inflammatory arthritis (IA) and osteoarthritis (OA) mandating the (...) initially identified, 186 met inclusion criteria. The task force emphasised the importance for the health professional to adopt a patient-centred framework within a biopsychosocial perspective, to have sufficient knowledge of IA and OA pathogenesis, and to be able to differentiate localised and generalised pain. Treatment is guided by scientific evidence and the assessment of patient needs, preferences and priorities; pain characteristics; previous and ongoing pain treatments; inflammation and joint

EvidenceUpdates2018

34. A randomized, double-blind, placebo-controlled Phase III trial of duloxetine in Japanese patients with knee pain due to osteoarthritis

A randomized, double-blind, placebo-controlled Phase III trial of duloxetine in Japanese patients with knee pain due to osteoarthritis 29713194 2018 05 03 1178-7090 11 2018 Journal of pain research J Pain Res A randomized, double-blind, placebo-controlled Phase III trial of duloxetine in Japanese patients with knee pain due to osteoarthritis. 809-821 10.2147/JPR.S164128 To examine the efficacy and safety of duloxetine in Japanese patients with knee pain due to osteoarthritis. Patients were (...) more frequent in the duloxetine than placebo group were somnolence, constipation, dry mouth, nausea, malaise, and decreased appetite. There were no marked changes in range of motion of the knee joint (efficacy), X-ray images, or Kellgren-Lawrence grade (safety) in either group. Duloxetine reduced pain and improved function in patients with knee osteoarthritis, without causing X-ray abnormalities or altered knee joint mobility. Reduced pain was associated with improved HRQoL. Adverse events were

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

35. Risk of myocardial infarction with use of selected non-steroidal anti-inflammatory drugs in patients with spondyloarthritis and osteoarthritis

Risk of myocardial infarction with use of selected non-steroidal anti-inflammatory drugs in patients with spondyloarthritis and osteoarthritis 29674321 2018 05 06 1468-2060 2018 Apr 19 Annals of the rheumatic diseases Ann. Rheum. Dis. Risk of myocardial infarction with use of selected non-steroidal anti-inflammatory drugs in patients with spondyloarthritis and osteoarthritis. annrheumdis-2018-213089 10.1136/annrheumdis-2018-213089 Spondyloarthritis (SpA) is associated with an increased risk (...) of myocardial infarction (MI) due to underlying inflammation and possibly due to medications such as certain non-steroidal anti-inflammatory drugs (NSAIDs). We sought to describe MI risk among patients with SpA who were prescribed NSAIDs, and to compare the pattern of risk in SpA with that in osteoarthritis (OA). Nested case-control studies were performed using The Health Improvement Network (THIN). Underlying cohorts included adults with incident SpA or OA who had > 1 NSAID prescription and no history of MI. Within

EvidenceUpdates2018

36. Fluoroscopic Guided Radiofrequency of Genicular Nerves for Pain Alleviation in Chronic Knee Osteoarthritis: A Single-Blind Randomized Controlled Trial

Fluoroscopic Guided Radiofrequency of Genicular Nerves for Pain Alleviation in Chronic Knee Osteoarthritis: A Single-Blind Randomized Controlled Trial 29565947 2018 03 22 2150-1149 21 2 2018 Mar Pain physician Pain Physician Fluoroscopic Guided Radiofrequency of Genicular Nerves for Pain Alleviation in Chronic Knee Osteoarthritis: A Single-Blind Randomized Controlled Trial. 169-177 Nowadays, pain and disability due to chronic knee arthritis is a very common problem in middle aged people. A lot (...) of modalities for management are available, including conservative analgesics and up to surgical interventions. Radiofrequency ablation of genicular nerves is assumed to be an effective less invasive and safe pain alleviation modality. To evaluate the efficacy of fluoroscopic guided radiofrequency neurotomy of the genicular nerves for alleviation of chronic pain and improvement of function in patients with knee osteoarthritis. A single-blind randomized controlled trial. Pain management unit

EvidenceUpdates2018

37. Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review.

Exercise interventions and patient beliefs for people with hip, knee or hip and knee osteoarthritis: a mixed methods review. BACKGROUND: Chronic peripheral joint pain due to osteoarthritis (OA) is extremely prevalent and a major cause of physical dysfunction and psychosocial distress. Exercise is recommended to reduce joint pain and improve physical function, but the effect of exercise on psychosocial function (health beliefs, depression, anxiety and quality of life) in this population (...) in the quantitative synthesis, studies had to be randomised controlled trials of land- or water-based exercise programmes compared with a control group consisting of no treatment or non-exercise intervention (such as medication, patient education) that measured either pain or function and at least one psychosocial outcome (self-efficacy, depression, anxiety, quality of life). Participants had to be aged 45 years or older, with a clinical diagnosis of OA (as defined by the study) or self-reported chronic hip

Cochrane2018

38. Diclofenac or etoricoxib, but not paracetamol, is effective for treating osteoarthritis

Diclofenac or etoricoxib, but not paracetamol, is effective for treating osteoarthritis NIHR DC | Signal - Diclofenac or etoricoxib, but not paracetamol, is effective for treating osteoarthritis Dissemination Centre Discover Portal NIHR DC Discover NIHR Signal Diclofenac or etoricoxib, but not paracetamol, is effective for treating osteoarthritis Published on 26 May 2016 This review aimed to identify the most effective drugs for pain relief in hip or knee osteoarthritis. Maximum dose diclofenac (...) . Why was this study needed? Osteoarthritis is the most common type of arthritis in the UK, and the leading cause of pain in older adults. The severity of pain and functional disability can vary from person to person, from mild symptoms that come and go, to more continuous and severe problems. NSAIDs are commonly used to treat symptoms of osteoarthritis. In the USA, about 65% of patients with osteoarthritis are prescribed NSAIDs. In England, each month, £5-6 million is spent in general

NIHR Dissemination Centre2018

39. The role of meniscal repair for prevention of early onset of osteoarthritis

The role of meniscal repair for prevention of early onset of osteoarthritis 29607459 2018 11 14 2197-1153 5 1 2018 Apr 02 Journal of experimental orthopaedics J Exp Orthop The role of meniscal repair for prevention of early onset of osteoarthritis. 10 10.1186/s40634-018-0122-z The meniscus plays an important role in the integrity of the knee joint. Therefore, meniscus tissue preserving techniques for the therapy of meniscus injuries seem to be reasonable. One of the important questions (...) is whether meniscal repair can prevent the knee joint from early onset of osteoarthritis. According to the review of the current literature, the principles of a successful meniscal repair are explained and the functional outcome and its impact on the prevention of osteoarthritis are analyzed in this article. Current data show a positive impact of a successful meniscus repair on the functional outcome in long-term. By this a protective effect on the development of osteoarthritis via the repair of meniscus

Journal of experimental orthopaedics2018 Full Text: Link to full Text with Trip Pro

40. Gamechanger? The Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients with Knee Osteoarthritis ? A Randomized Clinical Trial

Gamechanger? The Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients with Knee Osteoarthritis ? A Randomized Clinical Trial Gamechanger? The Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients with Knee Osteoarthritis – A Randomized Clinical Trial | Clinical Correlations Gamechanger? The Effect of Intra-articular Triamcinolone vs Saline on Knee Cartilage Volume and Pain in Patients with Knee Osteoarthritis (...) – A Randomized Clinical Trial April 6, 2018 By Rebecca Lazarus, MD Peer Reviewed Why does this matter? Osteoarthritis (OA) is a leading cause of disability in the United States and is the most common type of arthritis. The pathogenesis involves the progressive destruction of articular cartilage in a joint, which is accompanied by new bone formation and synovial proliferation. On a cellular level, this process is believed to involve mononuclear cells and pro-inflammatory mediators that promote

Clinical Correlations2018