Latest & greatest articles for osteoarthritis

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Top results for osteoarthritis

2. 2018 update of the EULAR recommendations for the management of hand osteoarthritis

2018 update of the EULAR recommendations for the management of hand osteoarthritis 30154087 2018 08 29 1468-2060 2018 Aug 28 Annals of the rheumatic diseases Ann. Rheum. Dis. 2018 update of the EULAR recommendations for the management of hand osteoarthritis. annrheumdis-2018-213826 10.1136/annrheumdis-2018-213826 Since publication of the European League Against Rheumatism (EULAR) recommendations for management of hand osteoarthritis (OA) in 2007 new evidence has emerged. The aim was to update (...) these recommendations. EULAR standardised operating procedures were followed. A systematic literature review was performed, collecting the evidence regarding all non-pharmacological, pharmacological and surgical treatment options for hand OA published to date. Based on the evidence and expert opinion from an international task force of 19 physicians, healthcare professionals and patients from 10 European countries formulated overarching principles and recommendations. Level of evidence, grade of recommendation

EvidenceUpdates2018

3. Triamcinolone acetonide extended-release in patients with osteoarthritis and type 2 diabetes: a randomized, phase 2 study

Triamcinolone acetonide extended-release in patients with osteoarthritis and type 2 diabetes: a randomized, phase 2 study 30203101 2018 09 11 1462-0332 2018 Sep 06 Rheumatology (Oxford, England) Rheumatology (Oxford) Triamcinolone acetonide extended-release in patients with osteoarthritis and type 2 diabetes: a randomized, phase 2 study. 10.1093/rheumatology/key265 Approximately 30% of patients with type 2 diabetes mellitus have knee osteoarthritis. IA corticosteroids used to manage (...) osteoarthritis pain can elevate blood glucose in these patients. We compared blood glucose levels following intra-articular injection of triamcinolone acetonide extended-release (TA-ER), an extended-release, microsphere-based triamcinolone acetonide formulation, vs standard triamcinolone acetonide crystalline suspension (TAcs) in patients with knee osteoarthritis and comorbid type 2 diabetes. In this double-blind, randomized, parallel-group, phase 2 study (NCT02762370), 33 patients with knee osteoarthritis

EvidenceUpdates2018

4. Effectiveness of low-dose radiation therapy on symptoms in patients with knee osteoarthritis: a randomised, double-blinded, sham-controlled trial

Effectiveness of low-dose radiation therapy on symptoms in patients with knee osteoarthritis: a randomised, double-blinded, sham-controlled trial 30366945 2018 10 27 1468-2060 2018 Oct 26 Annals of the rheumatic diseases Ann. Rheum. Dis. Effectiveness of low-dose radiation therapy on symptoms in patients with knee osteoarthritis: a randomised, double-blinded, sham-controlled trial. annrheumdis-2018-214104 10.1136/annrheumdis-2018-214104 Low-dose radiation therapy (LDRT) for benign disorders (...) such as knee osteoarthritis (OA) is widely used in some parts of the world, despite absence of controlled studies. We evaluated the effect of LDRT on symptoms and inflammation in patients with knee OA. In this randomised, double-blinded, sham-controlled clinical trial (RCT), we recruited patients with knee OA (clinical ACR criteria) in the Netherlands, aged ≥50 years, pain score ≥5/10 and non-responding to analgesics and exercise therapy. Patients were randomised 1:1 to receive LDRT (1 Gray per fraction

EvidenceUpdates2018

5. Diclofenac or etoricoxib, but not paracetamol, is effective for treating osteoarthritis

Diclofenac or etoricoxib, but not paracetamol, is effective for treating osteoarthritis Signal - Diclofenac or etoricoxib, but not paracetamol, is effective for treating osteoarthritis Dissemination Centre Discover Portal NIHR DC Discover Diclofenac or etoricoxib, but not paracetamol, is effective for treating osteoarthritis Published on 26 May 2016 This review aimed to identify the most effective drugs for pain relief in hip or knee osteoarthritis. High dose diclofenac or etoricoxib were (...) drew attention to two missed trials and a duplicate publication. This has not changed the overall message. Share your views on the research. Why was this study needed? Osteoarthritis is the most common type of arthritis in the UK and the leading cause of pain in older adults. The severity of pain and functional disability can vary from person to person, from mild symptoms that come and go to more continuous and severe problems. Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used

NIHR Dissemination Centre2018

6. People with osteoarthritis can benefit from exercise but may harbour myths about safety

People with osteoarthritis can benefit from exercise but may harbour myths about safety People with osteoarthritis can benefit from exercise but may harbour myths about safety Dissemination Centre Discover Portal NIHR DC Discover People with osteoarthritis can benefit from exercise but may harbour myths about safety Published on 21 August 2018 doi: Programmes that show people with osteoarthritis how to exercise safely may slightly improve pain scores, self-belief and social function (...) , but participants also report the myth that discomfort while exercising indicates on-going harm. The review combines evidence from 21 randomised controlled trials evaluating exercise in hip or knee osteoarthritis with 12 studies where people receiving the intervention were interviewed about the impact of exercise on their disease. Participants were men and women aged older than 45 years. Analysis of the randomised trials provides moderate- to low-quality evidence that exercise slightly improved pain

NIHR Dissemination Centre2018

8. Is four-week underwater treadmill exercise regimen compared to home exercise efficacious for pain relief and functional improvement in obese patients with knee osteoarthritis? A randomized controlled trial

Is four-week underwater treadmill exercise regimen compared to home exercise efficacious for pain relief and functional improvement in obese patients with knee osteoarthritis? A randomized controlled trial 30064262 2018 08 01 1477-0873 2018 Aug 01 Clinical rehabilitation Clin Rehabil Is four-week underwater treadmill exercise regimen compared to home exercise efficacious for pain relief and functional improvement in obese patients with knee osteoarthritis? A randomized controlled trial (...) . 269215518792041 10.1177/0269215518792041 To investigate the efficacy of a four-week underwater treadmill exercise regimen compared to a home exercise regimen relative to pain relief and functional improvement in obese patients with knee osteoarthritis. Single-blind randomized controlled trial. Outpatient. Eighty primary knee osteoarthritis with pain ⩾5/10 and body mass index ⩾25 kg/m 2 . Daily quadriceps exercise at home for 30 minutes (control group) or underwater treadmill exercise (study group) for 30

EvidenceUpdates2018

9. Effects of internet-based pain coping skills training before home exercise for individuals with hip osteoarthritis (HOPE trial): a randomised controlled trial

Effects of internet-based pain coping skills training before home exercise for individuals with hip osteoarthritis (HOPE trial): a randomised controlled trial 29794609 2018 08 16 1872-6623 159 9 2018 Sep Pain Pain Effects of internet-based pain coping skills training before home exercise for individuals with hip osteoarthritis (HOPE trial): a randomised controlled trial. 1833-1842 10.1097/j.pain.0000000000001281 This assessor-, therapist-, and participant-blinded randomised controlled trial (...) evaluated the effects of an automated internet-based pain coping skills training (PCST) program before home exercise for people with clinically diagnosed hip osteoarthritis. One hundred forty-four people were randomised to either the PCST group or the comparator group. In the first 8 weeks, the PCST group received online education and PCST, whereas the comparison group received online education only. From weeks 8 to 24, both groups visited a physiotherapist 5 times for home exercise prescription

EvidenceUpdates2018

10. Effectiveness and feasibility of acupuncture for knee osteoarthritis: a pilot randomized controlled trial

Effectiveness and feasibility of acupuncture for knee osteoarthritis: a pilot randomized controlled trial 30037276 2018 07 24 1477-0873 2018 Jul 01 Clinical rehabilitation Clin Rehabil Effectiveness and feasibility of acupuncture for knee osteoarthritis: a pilot randomized controlled trial. 269215518790632 10.1177/0269215518790632 To evaluate the effectiveness of acupuncture for pain relief and function improvement in patients with knee osteoarthritis and to determine the feasibility (...) of an eight-week acupuncture intervention. Pilot randomized controlled trial. Three teaching hospitals in China. Patients with knee osteoarthritis (Kellgren grade II or III). Patients were randomly assigned to an eight-week (three sessions per week) intervention of either traditional Chinese acupuncture or sham acupuncture. The primary outcome was response rate-the proportion of patients achieving score ⩾36% decrease in Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) pain

EvidenceUpdates2018

11. Efficacy of Hydroxychloroquine in Hand Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Trial

Efficacy of Hydroxychloroquine in Hand Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Trial 29125901 2018 08 29 2151-4658 70 9 2018 Sep Arthritis care & research Arthritis Care Res (Hoboken) Efficacy of Hydroxychloroquine in Hand Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Trial. 1320-1325 10.1002/acr.23471 To determine the symptom-modifying effect of hydroxychloroquine (HCQ) in hand osteoarthritis (OA). In this randomized, double-blind, multicenter trial (...) , patients with symptomatic hand OA received either HCQ 400 mg once a day or placebo during 24 weeks. The primary outcome was change of pain measured on a 100-mm visual analog scale (VAS) at 24 weeks. Secondary outcomes included decrease of pain at weeks 6 and 12 and change in Australian Canadian Hand Osteoarthritis Index (AUSCAN) and Arthritis Impact Measurement Scale 2 short form (AIMS2-SF) total scores. A total of 196 patients was included (placebo n = 98, HCQ n = 98). Mean ± SD age was 58.0 ± 7.6

EvidenceUpdates2018

12. 2018 EULAR recommendations for physical activity in people with inflammatory arthritis and osteoarthritis

2018 EULAR recommendations for physical activity in people with inflammatory arthritis and osteoarthritis 29997112 2018 08 11 1468-2060 77 9 2018 Sep Annals of the rheumatic diseases Ann. Rheum. Dis. 2018 EULAR recommendations for physical activity in people with inflammatory arthritis and osteoarthritis. 1251-1260 10.1136/annrheumdis-2018-213585 Regular physical activity (PA) is increasingly promoted for people with rheumatic and musculoskeletal diseases as well as the general population. We (...) evaluated if the public health recommendations for PA are applicable for people with inflammatory arthritis (iA; Rheumatoid Arthritis and Spondyloarthritis) and osteoarthritis (hip/knee OA) in order to develop evidence-based recommendations for advice and guidance on PA in clinical practice. The EULAR standardised operating procedures for the development of recommendations were followed. A task force (TF) (including rheumatologists, other medical specialists and physicians, health professionals, patient

EvidenceUpdates2018

13. Conventional and biologic disease-modifying anti-rheumatic drugs for osteoarthritis: a meta-analysis of randomized controlled trials

Conventional and biologic disease-modifying anti-rheumatic drugs for osteoarthritis: a meta-analysis of randomized controlled trials 29917100 2018 06 19 1462-0332 2018 Jun 16 Rheumatology (Oxford, England) Rheumatology (Oxford) Conventional and biologic disease-modifying anti-rheumatic drugs for osteoarthritis: a meta-analysis of randomized controlled trials. 10.1093/rheumatology/key131 The role of inflammation in OA is controversial and it is unclear whether suppressing inflammation (...) with conventional or biologic DMARDs is effective. A systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to compare DMARDs with placebo in participants with symptomatic OA. Databases (Medline, Embase, Allied and Complementary Medicine Database, Web of Science and Cochrane Library), conference abstracts and ClinicalTrials.gov were searched to end of November 2017 for placebo-controlled RCTs of DMARDs, including biologics, in symptomatic OA. Pain data at treatment peak time

EvidenceUpdates2018

14. The Ottawa Panel guidelines on programmes involving therapeutic exercise for the management of hand osteoarthritis

The Ottawa Panel guidelines on programmes involving therapeutic exercise for the management of hand osteoarthritis 29911409 2018 06 18 1477-0873 2018 Jun 01 Clinical rehabilitation Clin Rehabil The Ottawa Panel guidelines on programmes involving therapeutic exercise for the management of hand osteoarthritis. 269215518780973 10.1177/0269215518780973 To identify programmes involving therapeutic exercise that are effective for the management of hand osteoarthritis and to provide stakeholders (...) with updated, moderate to high-quality recommendations supporting exercises for hand osteoarthritis. A systematic search and adapted selection criteria included comparable trials with exercise programmes for managing hand osteoarthritis. Based on the evaluated evidence, a panel of experts reached consensus through a Delphi approach endorsing the recommendations. A hierarchical alphabetical grading system (A, B, C+, C, C-, D-, D, D+, E, F) was based on clinical importance (≥15%) and statistical significance

EvidenceUpdates2018

15. Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials

Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials Journals Library An error occurred retrieving content to display, please (...) try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> {{metadata.Title}} {{metadata.Headline}} The programme provides evidence for primary care for patients with osteoarthritis, but against enhancing current physical activity interventions (BEEP RCT) or including routine screening

NIHR HTA programme2018

16. Knee osteoarthritis

Knee osteoarthritis Top results for knee osteoarthritis - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box (...) and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for knee osteoarthritis The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical

Trip Latest and Greatest2018

17. Osteoarthritis

Osteoarthritis Top results for osteoarthritis - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing (...) the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for osteoarthritis The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines

Trip Latest and Greatest2018

18. Osteoarthritis

Osteoarthritis Autosynthesis - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button

Trip Evidence Maps2018

19. The effect of 12-week garlic supplementation on symptom relief in overweight or obese women with knee osteoarthritis

The effect of 12-week garlic supplementation on symptom relief in overweight or obese women with knee osteoarthritis 29790635 2018 05 23 1742-1241 2018 May 23 International journal of clinical practice Int. J. Clin. Pract. The effect of 12-week garlic supplementation on symptom relief in overweight or obese women with knee osteoarthritis. e13208 10.1111/ijcp.13208 Chronic joint pain and stiffness, and functional disability, are the major debilitating features of osteoarthritis (OA). The aim (...) of this study was to assess the effect of 12-week supplementation with a garlic supplement on knee osteoarthritis outcomes in overweight or obese women. Seventy-six postmenopausal overweight or obese women (25≤BMI≤40 kg/m 2 ) with medically diagnosed knee OA participated in this randomised double-blind, placebo-controlled, parallel-design trial. After randomisation into 2 groups, patients received a daily dose of either 1000 mg odourless garlic tablet, or placebo, for 12 weeks. The total Western Ontario

EvidenceUpdates2018

20. Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo-Controlled, Multinational Study

Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo-Controlled, Multinational Study 29664853 2018 06 15 1535-1386 100 8 2018 Apr 18 The Journal of bone and joint surgery. American volume J Bone Joint Surg Am Effects of a Single Intra-Articular Injection of a Microsphere Formulation of Triamcinolone Acetonide on Knee Osteoarthritis Pain: A Double-Blinded, Randomized, Placebo (...) -Controlled, Multinational Study. 666-677 10.2106/JBJS.17.00154 Intra-articular corticosteroids relieve osteoarthritis pain, but rapid systemic absorption limits efficacy. FX006, a novel, microsphere-based, extended-release triamcinolone acetonide (TA) formulation, prolongs TA joint residence and reduces systemic exposure compared with standard TA crystalline suspension (TAcs). We assessed symptomatic benefits and safety of FX006 compared with saline-solution placebo and TAcs. In this Phase-3, multicenter

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro