Latest & greatest articles for opioid

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Top results for opioid

21. Sustained Preoperative Opioid Use Is a Predictor of Continued Use Following Spine Surgery

Sustained Preoperative Opioid Use Is a Predictor of Continued Use Following Spine Surgery 29870441 2018 06 05 1535-1386 100 11 2018 Jun 06 The Journal of bone and joint surgery. American volume J Bone Joint Surg Am Sustained Preoperative Opioid Use Is a Predictor of Continued Use Following Spine Surgery. 914-921 10.2106/JBJS.17.00862 Preoperative opioid use is known to increase the likelihood of complications and inferior outcomes following spine surgery. We evaluated the association (...) of preoperative opioid use and other risk factors with postoperative opioid use. We queried 2006-2014 TRICARE insurance claims to identify adults who underwent lumbar interbody arthrodesis, lumbar discectomy, lumbar decompression, or lumbar posterolateral arthrodesis. The duration of preoperative opioid use was categorized as acute exposure, exposed without sustained use, intermediate sustained use, and chronic sustained use. Cox proportional-hazard models that adjusted for demographic factors, preoperative

EvidenceUpdates2018

23. Opioid

Opioid Top results for opioid - Trip Database or use your Google+ account Find evidence fast My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button (...) . An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for opioid The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical

Trip Latest and Greatest2018

24. Trends in opioid use in commercially insured and Medicare Advantage populations in 2007-16: retrospective cohort study.

Trends in opioid use in commercially insured and Medicare Advantage populations in 2007-16: retrospective cohort study. OBJECTIVE: To describe trends in the rate and daily dose of opioids used among commercial and Medicare Advantage beneficiaries from 2007 to 2016. DESIGN: Retrospective cohort study of administrative claims data. SETTING: National database of medical and pharmacy claims for commercially insured and Medicare Advantage beneficiaries in the United States. PARTICIPANTS: 48 million (...) individuals with any period of insurance coverage between 1 January 2007 and 31 December 2016, including commercial beneficiaries, Medicare Advantage beneficiaries aged 65 years and over, and Medicare Advantage beneficiaries under age 65 years (eligible owing to permanent disability). MAIN ENDPOINTS: Proportion of beneficiaries with any opioid prescription per quarter, average daily dose in milligram morphine equivalents (MME), and proportion of opioid use episodes that represented long term use. RESULTS

BMJ2018

26. Effects of Electroacupuncture on Opioid Consumption in Patients with Chronic Musculoskeletal Pain: A Multicenter Randomized Controlled Trial

Effects of Electroacupuncture on Opioid Consumption in Patients with Chronic Musculoskeletal Pain: A Multicenter Randomized Controlled Trial 29893942 2018 06 12 1526-4637 2018 Jun 08 Pain medicine (Malden, Mass.) Pain Med Effects of Electroacupuncture on Opioid Consumption in Patients with Chronic Musculoskeletal Pain: A Multicenter Randomized Controlled Trial. 10.1093/pm/pny113 To evaluate the efficacy and safety of electroacupuncture in reducing opioid consumption in patients with chronic (...) musculoskeletal pain. A randomized, participant-assessor-blinded, three-arm trial. Participants from three pain clinics and from the public. One hundred and eight adults with chronic pain who were taking opioids. All participants received pain and medication management education. Participants were randomly allocated to electroacupuncture (N = 48), sham electroacupuncture (N = 29), or education alone (N = 31) to receive relevant treatment for 12 weeks. The last group received electroacupuncture during

EvidenceUpdates2018

27. Medication for Opioid Use Disorder After Nonfatal Opioid Overdose and Association With Mortality: A Cohort Study.

Medication for Opioid Use Disorder After Nonfatal Opioid Overdose and Association With Mortality: A Cohort Study. Background: Opioid overdose survivors have an increased risk for death. Whether use of medications for opioid use disorder (MOUD) after overdose is associated with mortality is not known. Objective: To identify MOUD use after opioid overdose and its association with all-cause and opioid-related mortality. Design: Retrospective cohort study. Setting: 7 individually linked data sets (...) from Massachusetts government agencies. Participants: 17 568 Massachusetts adults without cancer who survived an opioid overdose between 2012 and 2014. Measurements: Three types of MOUD were examined: methadone maintenance treatment (MMT), buprenorphine, and naltrexone. Exposure to MOUD was identified at monthly intervals, and persons were considered exposed through the month after last receipt. A multivariable Cox proportional hazards model was used to examine MOUD as a monthly time-varying

Annals of Internal Medicine2018

28. Effect of restricting the legal supply of prescription opioids on buying through online illicit marketplaces: interrupted time series analysis.

Effect of restricting the legal supply of prescription opioids on buying through online illicit marketplaces: interrupted time series analysis. OBJECTIVE: To examine the effect on the trade in opioids through online illicit markets ("cryptomarkets") of the US Drug Enforcement Administration's ruling in 2014 to reschedule hydrocodone combination products. DESIGN: Interrupted time series analysis. SETTING: 31 of the world's largest cryptomarkets operating from October 2013 to July 2016. MAIN (...) OUTCOME MEASURES: The proportion of total transactions, advertised and active listings for prescription opioids, prescription sedatives, prescription steroids, prescription stimulants, and illicit opioids, and the composition of the prescription opioid market between the US and elsewhere. RESULTS: The sale of prescription opioids through US cryptomarkets increased after the schedule change, with no statistically significant changes in sales of prescription sedatives, prescription steroids

BMJ2018

29. Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care.

Mu-opioid antagonists for opioid-induced bowel dysfunction in people with cancer and people receiving palliative care. BACKGROUND: Opioid-induced bowel dysfunction (OIBD) is characterised by constipation, incomplete evacuation, bloating, and gastric reflux. It is one of the major adverse events of treatment for pain in cancer and in palliative care, resulting in increased morbidity and reduced quality of life.This is an update of two Cochrane reviews. One was published in 2011, Issue 1 (...) on laxatives and methylnaltrexone for the management of constipation in people receiving palliative care; this was updated in 2015 and excluded methylnaltrexone. The other was published in 2008, Issue 4 on mu-opioid antagonists (MOA) for OIBD. In this updated review, we only included trials on MOA (including methylnaltrexone) for OIBD in people with cancer and people receiving palliative care. OBJECTIVES: To assess the effectiveness and safety of MOA for OIBD in people with cancer and people receiving

Cochrane2018

30. Parenteral opioids for maternal pain management in labour.

Parenteral opioids for maternal pain management in labour. BACKGROUND: Parenteral opioids (intramuscular and intravenous drugs including patient-controlled analgesia) are used for pain relief in labour in many countries throughout the world. This review is an update of a review first published in 2010. OBJECTIVES: To assess the effectiveness, safety and acceptability to women of different types, doses and modes of administration of parenteral opioid analgesia in labour. A second objective (...) is to assess the effects of opioids in labour on the baby in terms of safety, condition at birth and early feeding. SEARCH METHODS: We searched Cochrane Pregnancy and Childbirth's Trials Register, ClinicalTrials.gov, the WHO International Clinical Trials Registry Platform (ICTRP) (11 May 2017) and reference lists of retrieved studies. SELECTION CRITERIA: We included randomised controlled trials examining the use of intramuscular or intravenous opioids (including patient-controlled analgesia) for women

Cochrane2018

32. Opioid Use Disorder - Diagnosis and Management in Primary Care

Opioid Use Disorder - Diagnosis and Management in Primary Care Opioid Use Disorder - Diagnosis and Management in Primary Care - Province of British Columbia Search default_collection default_frontend MENU theme_1_collection theme_1_frontend theme_1_collection theme_1_frontend British Columbians & Our Governments theme_3_collection theme_3_frontend theme_3_collection theme_3_frontend Health theme_2_collection theme_2_frontend theme_2_collection theme_2_frontend Birth, Adoption, Death, Marriage (...) Employment, Business & Economic Development theme_14_collection theme_14_frontend theme_14_collection theme_14_frontend Tourism & Immigration theme_15_collection theme_15_frontend theme_15_collection theme_15_frontend Family & Social Supports default_collection data_frontend default_collection data_frontend Data Section Navigation Opioid Use Disorder - Diagnosis and Management in Primary Care Effective Date: June 1 st , 2018 Recommendations and Topics Scope This guideline presents recommendations

Clinical Practice Guidelines and Protocols in British Columbia2018

33. Weekly and Monthly Subcutaneous Buprenorphine Depot Formulations vs Daily Sublingual Buprenorphine With Naloxone for Treatment of Opioid Use Disorder: A Randomized Clinical Trial.

Weekly and Monthly Subcutaneous Buprenorphine Depot Formulations vs Daily Sublingual Buprenorphine With Naloxone for Treatment of Opioid Use Disorder: A Randomized Clinical Trial. 29799968 2018 06 05 2168-6114 178 6 2018 Jun 01 JAMA internal medicine JAMA Intern Med Weekly and Monthly Subcutaneous Buprenorphine Depot Formulations vs Daily Sublingual Buprenorphine With Naloxone for Treatment of Opioid Use Disorder: A Randomized Clinical Trial. 764-773 10.1001/jamainternmed.2018.1052 (...) Buprenorphine treatment for opioid use disorder may be improved by sustained-release formulations. To determine whether treatment involving novel weekly and monthly subcutaneous (SC) buprenorphine depot formulations is noninferior to a daily sublingual (SL) combination of buprenorphine hydrochloride and naloxone hydrochloride in the treatment of opioid use disorder. This outpatient, double-blind, double-dummy randomized clinical trial was conducted at 35 sites in the United States from December 29, 2015

EvidenceUpdates2018

34. Efficacy of opioids versus placebo in chronic pain: a systematic review and meta-analysis of enriched enrollment randomized withdrawal trials

Efficacy of opioids versus placebo in chronic pain: a systematic review and meta-analysis of enriched enrollment randomized withdrawal trials 29765246 2018 05 18 1178-7090 11 2018 Journal of pain research J Pain Res Efficacy of opioids versus placebo in chronic pain: a systematic review and meta-analysis of enriched enrollment randomized withdrawal trials. 923-934 10.2147/JPR.S160255 Opioids have been used for millennia for the treatment of pain. However, the long-term efficacy of opioids (...) to treat chronic non-cancer pain continues to be debated. To evaluate opioids' efficacy in chronic non-cancer pain, we performed a meta-analysis of published clinical trials for μ-opioid receptor agonists performed for US Food and Drug Administration approval. MEDLINE and Cochrane trial register were searched for enriched enrollment randomized withdrawal studies (before June 2016). Selection criteria included: adults, ≥10 subjects per arm, any chronic pain condition, double-blind treatment period

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

35. Recent opioid use and fall-related injury among older patients with trauma

Recent opioid use and fall-related injury among older patients with trauma 29685910 2018 05 03 1488-2329 190 16 2018 Apr 23 CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne CMAJ Recent opioid use and fall-related injury among older patients with trauma. E500-E506 10.1503/cmaj.171286 Evidence for an association between opioid use and risk of falls or fractures in older adults is inconsistent. We examine the association between recent opioid use (...) and the risk, as well as the clinical outcomes, of fall-related injuries in a large trauma population of older adults. In a retrospective, observational, multicentre cohort study conducted on registry data, we included all patients aged 65 years and older who were admitted (hospital stay > 2 d) for injury in 57 trauma centres in the province of Quebec, Canada, between 2004 and 2014. We looked at opioid prescriptions filled in the 2 weeks preceding the trauma in patients who sustained a fall, compared

EvidenceUpdates2018 Full Text: Link to full Text with Trip Pro

36. Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and network meta-analysis

Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and network meta-analysis 29730600 2018 06 06 1468-3288 2018 May 05 Gut Gut Efficacy of pharmacological therapies for the treatment of opioid-induced constipation: systematic review and network meta-analysis. gutjnl-2018-316001 10.1136/gutjnl-2018-316001 Opioids are increasingly prescribed in the West and have deleterious GI consequences. Pharmacological therapies to treat opioid-induced

EvidenceUpdates2018

37. Patterns of Potential Opioid Misuse and Subsequent Adverse Outcomes in Medicare, 2008 to 2012.

Patterns of Potential Opioid Misuse and Subsequent Adverse Outcomes in Medicare, 2008 to 2012. Background: Providers are increasingly being expected to examine their patients' opioid treatment histories before writing new opioid prescriptions. However, little evidence exists on how patterns of potential opioid misuse are associated with subsequent adverse outcomes nationally. Objective: To estimate how a range of patterns of potential opioid misuse relate to adverse outcomes during (...) the subsequent year. Design: Observational study comparing outcomes for Medicare enrollees with potential opioid misuse patterns versus those for beneficiaries with no such patterns, adjusting for patient characteristics. Setting: Medicare, 2008 to 2012. Patients: A 5% sample of beneficiaries who had an opioid prescription without a cancer diagnosis. Measurements: Several measures for opioid misuse were defined on the basis of drug quantity, overlapping prescriptions, use of multiple prescribers

Annals of Internal Medicine2018

38. Neer Award 2018: the effect of preoperative education on opioid consumption in patients undergoing arthroscopic rotator cuff repair: a prospective, randomized clinical trial

Neer Award 2018: the effect of preoperative education on opioid consumption in patients undergoing arthroscopic rotator cuff repair: a prospective, randomized clinical trial 29599038 2018 05 20 1532-6500 27 6 2018 Jun Journal of shoulder and elbow surgery J Shoulder Elbow Surg Neer Award 2018: the effect of preoperative education on opioid consumption in patients undergoing arthroscopic rotator cuff repair: a prospective, randomized clinical trial. 962-967 S1058-2746(18)30120-4 10.1016/j.jse (...) .2018.02.039 Opioids are commonly administered for the treatment of acute and chronic pain symptoms. The current health care system is struggling to deal with increasing medication abuse and rising mortality rates from overdose. Preoperative patient-targeted education on opioid use is an avenue yet to be explored. The purpose of the study was to determine whether preoperative narcotics education reduces consumption after arthroscopic rotator cuff repair (ARCR). Patients undergoing primary ARCR at our

EvidenceUpdates2018

39. Managing infants born to mothers who have used opioids during pregnancy

Managing infants born to mothers who have used opioids during pregnancy The incidence of infant opioid withdrawal has grown rapidly in many countries, including Canada, in the last decade, presenting significant health and early brain development concerns. Increased prenatal exposure to opioids reflects rising prescription opioid use as well as the presence of both illegal opiates and opioid-substitution therapies. Infants are at high risk for experiencing symptoms of abstinence (...) or withdrawal that may require assessment and treatment. This practice point focuses specifically on the effect(s) of opioid withdrawal and current management strategies in the care of infants born to mothers with opioid dependency. Keywords: Discharge planning; Management; NAS; NPI; Treatment strategies

Canadian Paediatric Society2018

40. Impact of Preadmission Opioid Treatment on 1-Year Mortality Following Nonsurgical Intensive Care

Impact of Preadmission Opioid Treatment on 1-Year Mortality Following Nonsurgical Intensive Care 29528945 2018 03 12 1530-0293 2018 Mar 09 Critical care medicine Crit. Care Med. Impact of Preadmission Opioid Treatment on 1-Year Mortality Following Nonsurgical Intensive Care. 10.1097/CCM.0000000000003080 Compare all-cause mortality following nonsurgical ICU admission for opioid users with nonusers. Nationwide register-based cohort study. All 43 ICUs in Denmark (7,028,668 citizens cumulatively (...) during the study period). The Danish National Health Service provides universal healthcare, guaranteeing equal access to healthcare along with partial reimbursement for prescribed drugs. All 118,388 nonsurgical patients admitted to an ICU from 2005 to 2014. Patients were categorized according to timing of last redeemed opioid prescription before admission: current user (prior 0-30 d), recent user (prior 31-365 d), former user (prior 365+ d), or nonuser (no prescription since 1994). All-cause

EvidenceUpdates2018