Latest & greatest articles for ondansetron

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Top results for ondansetron

41. A prospective randomized trial of the antiemetic efficacy and cost-effectiveness of intravenous and orally disintegrating tablet of ondansetron in children with cancer

A prospective randomized trial of the antiemetic efficacy and cost-effectiveness of intravenous and orally disintegrating tablet of ondansetron in children with cancer A prospective randomized trial of the antiemetic efficacy and cost-effectiveness of intravenous and orally disintegrating tablet of ondansetron in children with cancer A prospective randomized trial of the antiemetic efficacy and cost-effectiveness of intravenous and orally disintegrating tablet of ondansetron in children (...) with cancer Corapcioglu F, Sarper N Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The study compared orally disintegrating tablets (ODT) and intravenous (IV) formulations of ondansetron in controlling nausea and vomiting in children

NHS Economic Evaluation Database.2005

42. Ondansetron for the prevention and treatment of nausea and vomiting following pediatric strabismus surgery

Ondansetron for the prevention and treatment of nausea and vomiting following pediatric strabismus surgery Ondansetron for the prevention and treatment of nausea and vomiting following pediatric strabismus surgery Ondansetron for the prevention and treatment of nausea and vomiting following pediatric strabismus surgery Caron E, Bussieres J F, Lebel D, Mathews S, Milot J, Jacob J L, Moride Y, Lortie L Record Status This is a critical abstract of an economic evaluation that meets the criteria (...) for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of intravenous (0.1 mg/kg) plus oral ondansetron (0.15 mg/kg every 8 hours when needed) for the prevention and treatment of nausea and vomiting. This was compared to treatment with intravenous droperidol (0.05 mg/kg) plus oral dimenhydrinate (1.25 mg/kg every 8 hours when

NHS Economic Evaluation Database.2003

43. The efficacy and cost-effectiveness of prophylactic 5-hydroxytryptamine3 receptor antagonists: tropisetron, ondansetron and dolasetron

The efficacy and cost-effectiveness of prophylactic 5-hydroxytryptamine3 receptor antagonists: tropisetron, ondansetron and dolasetron The efficacy and cost-effectiveness of prophylactic 5-hydroxytryptamine3 receptor antagonists: tropisetron, ondansetron and dolasetron The efficacy and cost-effectiveness of prophylactic 5-hydroxytryptamine3 receptor antagonists: tropisetron, ondansetron and dolasetron Paech M J, Rucklidge M W, Banks S L, Gurrin L C, Orlikowski C E P, Pavy T J Record Status (...) This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of tropisetron 2 mg at induction, ondansetron 4 mg at induction, and dolasetron 12.5 mg at the end of surgery to prevent postoperative nausea and vomiting (PONV) after major open abdominal

NHS Economic Evaluation Database.2003

44. A comparison of the costs and efficacy of ondansetron and dolasetron in the prophylaxis of postoperative vomiting in pediatric patients undergoing ambulatory surgery

A comparison of the costs and efficacy of ondansetron and dolasetron in the prophylaxis of postoperative vomiting in pediatric patients undergoing ambulatory surgery A comparison of the costs and efficacy of ondansetron and dolasetron in the prophylaxis of postoperative vomiting in pediatric patients undergoing ambulatory surgery A comparison of the costs and efficacy of ondansetron and dolasetron in the prophylaxis of postoperative vomiting in pediatric patients undergoing ambulatory surgery (...) Olutoye O, Jantzen E C, Alexis R, Rajchert D, Schreiner M S, Watcha M F Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of dolasetron versus ondansetron in the prevention of postoperative vomiting (POV) in paediatric

NHS Economic Evaluation Database.2003

45. Management of post-strabismus nausea and vomiting in children using ondansetron: a value-based comparison of outcomes

Management of post-strabismus nausea and vomiting in children using ondansetron: a value-based comparison of outcomes Management of post-strabismus nausea and vomiting in children using ondansetron: a value-based comparison of outcomes Management of post-strabismus nausea and vomiting in children using ondansetron: a value-based comparison of outcomes Sennaraj B, Shende D, Sadhasivam S, Ilavajady S, Jagan D Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The use of prophylactic ondansetron (PO), 100 microg/kg intravenously (i.v.) for the treatment of postoperative nausea and vomiting (PONV) in children undergoing strabismus repair. Type of intervention Primary prevention (prophylaxis). Economic study type Cost

NHS Economic Evaluation Database.2002

46. Cost-efficacy analysis of ondansetron regimens for control of emesis induced by noncisplatin, moderately emetogenic chemotherapy

Cost-efficacy analysis of ondansetron regimens for control of emesis induced by noncisplatin, moderately emetogenic chemotherapy Cost-efficacy analysis of ondansetron regimens for control of emesis induced by noncisplatin, moderately emetogenic chemotherapy Cost-efficacy analysis of ondansetron regimens for control of emesis induced by noncisplatin, moderately emetogenic chemotherapy Lachaine J, Laurier C Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Twenty-two ondansetron regimens (i.e. serotonin antagonists) for the control of emesis induced by noncisplatin, moderately emetogenic chemotherapy were studied. Full details of the regimens compared were reported in the paper. Type of intervention Treatment. Economic

NHS Economic Evaluation Database.2002

47. Double-blind comparative trial of oral ondansetron versus oral granisetron versus IV ondansetron in the prevention of nausea and vomiting associated with highly emetogenic preparative regimens prior to stem cell transplantation

Double-blind comparative trial of oral ondansetron versus oral granisetron versus IV ondansetron in the prevention of nausea and vomiting associated with highly emetogenic preparative regimens prior to stem cell transplantation Double-blind comparative trial of oral ondansetron versus oral granisetron versus IV ondansetron in the prevention of nausea and vomiting associated with highly emetogenic preparative regimens prior to stem cell transplantation Double-blind comparative trial of oral (...) ondansetron versus oral granisetron versus IV ondansetron in the prevention of nausea and vomiting associated with highly emetogenic preparative regimens prior to stem cell transplantation Fox-Geiman M P, Fisher S G, Kiley K, Fletcher-Gonzalez D, Porter N, Stiff P Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment

NHS Economic Evaluation Database.2001

48. Evaluation of outcomes in converting from intravenous ondansetron to oral granisetron: an observational study

Evaluation of outcomes in converting from intravenous ondansetron to oral granisetron: an observational study Evaluation of outcomes in converting from intravenous ondansetron to oral granisetron: an observational study Evaluation of outcomes in converting from intravenous ondansetron to oral granisetron: an observational study McCune J S, Oertel M D, Pfeifer D, Houston S A, Bingham A, Sawyer W T, Lindley C M Record Status This is a critical abstract of an economic evaluation that meets (...) to compare the groups in the three periods considered. The two populations (Periods 1 and 2, compared with Period 3) were comparable with respect to demographic characteristics and clinical conditions. Effectiveness results The effectiveness results were as follows: The frequency of total control in ondansetron patients was 56% and granisetron patients 60% in the first population (Periods 1 and 2), and 50% in ondansetron patients and 54% in granisetron patients in Period 3. Frequency of major control

NHS Economic Evaluation Database.2001

49. Dexamethasone is a cost-effective alternative to ondansetron in preventing PONV after paediatric strabismus repair

Dexamethasone is a cost-effective alternative to ondansetron in preventing PONV after paediatric strabismus repair Dexamethasone is a cost-effective alternative to ondansetron in preventing PONV after paediatric strabismus repair Dexamethasone is a cost-effective alternative to ondansetron in preventing PONV after paediatric strabismus repair Subramaniam B, Madan R, Sadhasivam S, Sennaraj B, Tamilselvan P, Rajeshwari S, Jagan D, Shende D Record Status This is a critical abstract of an economic (...) evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology The intervention health technologies were the use of prophylactic ondansetron and dexamethasone in the prevention of postoperative nausea and vomiting (PONV) in children undergoing strabismus repair. Type of intervention Secondary prevention

NHS Economic Evaluation Database.2001

50. Ondansetron for reduction of drinking among biologically predisposed alcoholic patients: A randomized controlled trial.

Ondansetron for reduction of drinking among biologically predisposed alcoholic patients: A randomized controlled trial. 10944641 2000 09 06 2000 09 06 2016 10 17 0098-7484 284 8 2000 Aug 23-30 JAMA JAMA Ondansetron for reduction of drinking among biologically predisposed alcoholic patients: A randomized controlled trial. 963-71 Early-onset alcoholism differs from late-onset alcoholism by its association with greater serotonergic abnormality and antisocial behaviors. Thus, individuals with early (...) -onset alcoholism may be responsive to treatment with a selective serotonergic agent. To test the hypothesis that drinking outcomes associated with early vs late-onset alcoholism are differentially improved by the selective 5-HT(3) (serotonin) antagonist ondansetron. Double-blind, randomized, placebo-controlled clinical trial. University of Texas Health Science Center in Houston (April 1995-June 1998) and University of Texas Health Science Center in San Antonio (July 1998-December 1999). A total

JAMA2000

51. Granisetron is equivalent to ondansetron for prophylaxis of chemotherapy-induced nausea and vomiting: results of a meta-analysis of randomized controlled trials

Granisetron is equivalent to ondansetron for prophylaxis of chemotherapy-induced nausea and vomiting: results of a meta-analysis of randomized controlled trials Granisetron is equivalent to ondansetron for prophylaxis of chemotherapy-induced nausea and vomiting: results of a meta-analysis of randomized controlled trials Granisetron is equivalent to ondansetron for prophylaxis of chemotherapy-induced nausea and vomiting: results of a meta-analysis of randomized controlled trials del Giglio (...) A, Soares H P, Caparroz C, Castro P C Authors' objectives To compare granisetron with ondansetron in the prophylaxis of chemotherapy-induced nausea and vomiting. Searching MEDLINE and Cancerlit were searched from 1990 to 1999. Full publications and abstracts written in any language were eligible for inclusion. The references lists of the identified articles were searched for additional studies. Study selection Study designs of evaluations included in the review Randomised controlled trials (RCTs

DARE.2000

52. A comparison of the costs and efficacy of ondansetron versus dolasetron for antiemetic prophylaxis

A comparison of the costs and efficacy of ondansetron versus dolasetron for antiemetic prophylaxis A comparison of the costs and efficacy of ondansetron versus dolasetron for antiemetic prophylaxis A comparison of the costs and efficacy of ondansetron versus dolasetron for antiemetic prophylaxis Zarate E, Watcha M F, White P F, Klein K W, Rego M S, Stewart D G Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract (...) of detecting a 30% difference in the success rates for preventing PONV, assuming the success rates for 4 and 8 mg of ondansetron IV to be similar to those reported in the meta-analysis). A total of 200 patients were randomly assigned to receive one of four IV antiemetic study medications: (1) 12.5 mg of dolasetron (n = 50, mean (SD) age 45 (14) years); (2) 25 mg of dolasetron (n = 51, mean (SD) age 44 (14) years); (3) 4 mg of ondansetron (n = 49, mean (SD) age 45 (14) years); and (4) 8 mg of ondansetron (n

NHS Economic Evaluation Database.2000

53. Cost-effectiveness of prophylactic antiemetic therapy with ondansetron, droperidol, or placebo

Cost-effectiveness of prophylactic antiemetic therapy with ondansetron, droperidol, or placebo Cost-effectiveness of prophylactic antiemetic therapy with ondansetron, droperidol, or placebo Cost-effectiveness of prophylactic antiemetic therapy with ondansetron, droperidol, or placebo Hill R P, Lubarsky D A, Phillips-Bute B, Fortney J T, Creed M R, Glass P S, Gan T J Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each (...) abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. Health technology Three prophylactic intravenous regimens for post-operative nausea and vomiting (PONV) were assessed. The three regiments were ondansetron 4 mg, droperidol 0.625 mg, and droperidol 1.25 mg. Type of intervention Primary prevention (anti-emetic therapy). Economic study type Cost-effectiveness analysis. Study

NHS Economic Evaluation Database.2000

54. Effect of decreasing afferent vagal activity with ondansetron on symptoms of bulimia nervosa: a randomised, double-blind trial.

Effect of decreasing afferent vagal activity with ondansetron on symptoms of bulimia nervosa: a randomised, double-blind trial. 10711927 2000 03 21 2000 03 21 2016 11 24 0140-6736 355 9206 2000 Mar 04 Lancet (London, England) Lancet Effect of decreasing afferent vagal activity with ondansetron on symptoms of bulimia nervosa: a randomised, double-blind trial. 792-7 Several lines of evidence have led us to postulate that afferent vagal hyperactivity could be an important factor (...) in the pathophysiology of the eating disorder bulimia nervosa. Ondansetron is a peripherally active antagonist of the serotonin receptor 5-HT3, and is marketed for prevention of vagally-mediated emesis caused by cancer chemotherapeutic agents. We investigated the effects of ondansetron on bulimic behaviours in patients with severe and chronic bulimia nervosa in a randomised, double-blind, placebo-controlled study. We enrolled patients with severe bulimia nervosa (at least seven coupled binge/vomit episodes per week

Lancet2000

55. Dexamethasone alone or in combination with ondansetron for the prevention of delayed nausea and vomiting induced by chemotherapy. The Italian Group for Antiemetic Research.

Dexamethasone alone or in combination with ondansetron for the prevention of delayed nausea and vomiting induced by chemotherapy. The Italian Group for Antiemetic Research. 10824073 2000 05 25 2000 05 25 2013 11 21 0028-4793 342 21 2000 May 25 The New England journal of medicine N. Engl. J. Med. Dexamethasone alone or in combination with ondansetron for the prevention of delayed nausea and vomiting induced by chemotherapy. The Italian Group for Antiemetic Research. 1554-9 The prevention (...) of delayed nausea and vomiting caused by moderately emetogenic chemotherapy for cancer has not been studied systematically. We enrolled patients who were scheduled to receive chemotherapy for the first time in a double-blind, randomized, multicenter study. All the patients received ondansetron combined with dexamethasone for prophylaxis against emesis that might occur within 24 hours after the start of chemotherapy (acute emesis). They were then divided into two groups: patients who did not have either

NEJM2000

56. Prophylactic ondansetron for post-operative emesis: meta-analysis of its effectiveness in patients with and without a previous history of motion sickness

Prophylactic ondansetron for post-operative emesis: meta-analysis of its effectiveness in patients with and without a previous history of motion sickness Prophylactic ondansetron for post-operative emesis: meta-analysis of its effectiveness in patients with and without a previous history of motion sickness Prophylactic ondansetron for post-operative emesis: meta-analysis of its effectiveness in patients with and without a previous history of motion sickness Figueredo E, Canosa L Authors (...) ' objectives To assess the post-operative anti-emetic efficacy of 4 and 8 mg of ondansetron in adult patients with (+) and without (-) a previous history of motion sickness (PHMS). Searching The authors searched MEDLINE and EMBASE from January 1990 to August 1998 using the keywords: 'ondansetron', 'anaesthesia/anesthesia' and 'vomiting'. There were no language restrictions. Additional reports were identified from the reference sections of retrieved studies and from two previous meta-analyses. The authors

DARE.1999

57. A systematic review of the antiemetic efficacy of prophylactic ondansetron compared with droperidol and with metoclopramide in children

A systematic review of the antiemetic efficacy of prophylactic ondansetron compared with droperidol and with metoclopramide in children A systematic review of the antiemetic efficacy of prophylactic ondansetron compared with droperidol and with metoclopramide in children A systematic review of the antiemetic efficacy of prophylactic ondansetron compared with droperidol and with metoclopramide in children Lim L, Dear K B, Heller R F Authors' objectives To compare prophylactic ondansetron (...) with metoclopramide and with droperidol in the prevention of post-operative vomiting (POV) in children. Searching Details of the search strategy were presented in a companion paper (see Other Publications of Related Interest no.1). Searches were conducted of MEDLINE from 1966, EMBASE from 1987, and Globe (a non- commercial database) from 1987, using the following index terms: 'ondansetron', 'metoclopramide', 'droperidol' and 'post-operative'. Studies published in any language were considered. Additional material

DARE.1999

58. A systematic review of the antiemetic efficacy of prophylactic ondansetron compared with metoclopramide and with droperidol in adults

A systematic review of the antiemetic efficacy of prophylactic ondansetron compared with metoclopramide and with droperidol in adults A systematic review of the antiemetic efficacy of prophylactic ondansetron compared with metoclopramide and with droperidol in adults A systematic review of the antiemetic efficacy of prophylactic ondansetron compared with metoclopramide and with droperidol in adults Lim L, Dear K B, Heller R F Authors' objectives To compare prophylactic ondansetron (...) with metoclopramide and with droperidol in the prevention of post-operative vomiting (POV) in adults. Searching MEDLINE was searched from 1966, EMBASE from 1987, and Globe (a non-commercial database) from 1987, using the following index terms: 'ondansetron', 'metoclopramide', 'droperidol' and 'post-operative'. Studies published in any language were considered. Additional material was located by examining references from identified articles, review articles of the drugs studied, and conference abstracts

DARE.1999

59. Systematic review of ondansetron for the prevention and treatment of postoperative nausea and vomiting in adults

Systematic review of ondansetron for the prevention and treatment of postoperative nausea and vomiting in adults Systematic review of ondansetron for the prevention and treatment of postoperative nausea and vomiting in adults Systematic review of ondansetron for the prevention and treatment of postoperative nausea and vomiting in adults Cox F Authors' objectives To determine the efficacy and safety of ondansetron for the prevention and treatment of post-operative nausea and vomiting in adults (...) . Searching English language publications were sought in the following databases; EMBASE (1997); CINAHL (1990 to date); MEDLINE (1990 to date) and Cochrane Library (1998 Issue 1). The search used the combination (ondansetron and human and adults and (emesis or nausea or vomiting)) not (chemotherapy or cancer). Additional reports were identified from reference lists of retrieved reports and from review articles of PONV. The manufacturer of ondansetron supplied a review of the literature. A handsearch

DARE.1999

60. Comparative efficacy and safety of ondansetron, droperidol, and metoclopramide for preventing postoperative nausea and vomiting: a meta-analysis

Comparative efficacy and safety of ondansetron, droperidol, and metoclopramide for preventing postoperative nausea and vomiting: a meta-analysis Comparative efficacy and safety of ondansetron, droperidol, and metoclopramide for preventing postoperative nausea and vomiting: a meta-analysis Comparative efficacy and safety of ondansetron, droperidol, and metoclopramide for preventing postoperative nausea and vomiting: a meta-analysis Domino K B, Anderson E A, Polissar N L, Posner K L Authors (...) ' objectives To determine the relative efficacy and safety of the following drugs used prophylactically for the prevention of post-operative nausea and vomiting: ondansetron; droperidol; and metoclopramide. Searching A search was conducted of MEDLINE from January 1966 to May 1998 using the following terms: 'prevention', 'postoperative complications', 'nausea and vomiting', separately for 'ondansetron', 'droperidol' and 'metoclopramide'. A manual search was conducted of the table of contents in English

DARE.1999