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Latest & greatest articles for obesity
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on obesity or other clinical topics then use Trip today.
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Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass for obesity (YOMEGA): a multicentre, randomised, open-label, non-inferiority trial. BACKGROUND: One anastomosis gastric bypass (OAGB) is increasingly used in the treatment of morbid obesity. However, the efficacy and safety outcomes of this procedure remain debated. We report the results of a randomised trial (YOMEGA) comparing the outcomes of OAGB versus standard Roux-en-Y gastric bypass (RYGB). METHODS (...) : This prospective, multicentre, randomised non-inferiority trial, was held in nine obesity centres in France. Patients were eligible for inclusion if their body-mass index (BMI) was 40 kg/m 2 or higher, or 35 kg/m 2 or higher with the presence of at least one comorbidity (type 2 diabetes, high blood pressure, obstructive sleep apnoea, dyslipidaemia, or arthritis), and were aged 18-65 years. Key exclusion criteria were a history of oesophagitis, Barrett's oesophagus, severe gastro-oesophageal reflux disease
Obesity. The role of internists in evaluating obesity is to assess the burden of weight-related disease, mitigate secondary causes of weight gain (medications, sleep deprivation), and solicit patient motivation for weight loss. Internists should assess these factors and emphasize the importance of weight loss for the individual patient. All patients wishing to lose weight should be encouraged to monitor their diet and physical activity and should be referred to high-intensity behavioral (...) programs. Some patients with obesity may also benefit from pharmacotherapy or bariatric surgery.
Effect of Integrated Behavioral Weight Loss Treatment and Problem-Solving Therapy on Body Mass Index and Depressive Symptoms Among Patients With Obesity and Depression: The RAINBOW Randomized Clinical Trial. Importance: Coexisting obesity and depression exacerbate morbidity and disability, but effective treatments remain elusive. Objective: To test the hypothesis that an integrated collaborative care intervention would significantly improve both obesity and depression at 12 months compared (...) participants randomly assigned to the intervention (n = 204) or the usual care control group (n = 205) received medical care from their personal physicians as usual, received information on routine services for obesity and depression at their clinic, and received wireless physical activity trackers. Intervention participants also received a 12-month intervention that integrated a Diabetes Prevention Program-based behavioral weight loss treatment with problem-solving therapy for depression and, if indicated
Effect of Multinutrient Supplementation and Food-Related Behavioral Activation Therapy on Prevention of Major Depressive Disorder Among Overweight or Obese Adults With Subsyndromal Depressive Symptoms: The MooDFOOD Randomized Clinical Trial. Importance: Effects of nutritional interventions on the prevention of major depressive disorder (MDD) in overweight adults are unknown. Objective: To examine the effect of 2 nutritional strategies (multinutrient supplementation, food-related behavioral (...) groups and 24 patients in the supplementation with therapy group were hospitalized, and 26 patients in the supplementation-only group were hospitalized. Conclusions and Relevance: Among overweight or obese adults with subsyndromal depressive symptoms, multinutrient supplementation compared with placebo and food-related behavioral activation therapy compared with no therapy did not reduce episodes of major depressive disorder during 1 year. These findings do not support the use of these interventions
A total diet replacement programme helped obese people lose weight and keep weight off Total diet replacement for weight loss in obesity Dissemination Centre Discover Portal NIHR DC Discover A total diet replacement programme helped obese people lose weight and keep weight off Published on 18 December 2018 doi: A programme of weekly behavioural support with total diet replacement led to over 7kg greater weight loss than usual care in primary care. This weight loss was maintained for a year (...) ) containing 810 kcal per day. After eight weeks of this low calorie diet, conventional meals were gradually reintroduced. This trial provides evidence that the rapid weight loss from these replacement diets can be maintained for a reasonable time and so could be considered as a treatment option for anyone who is obese and needs support to lose weight. Share your views on the research. Why was this study needed? In 2016, 26% of adults in England were obese. Obesity can lead to several medical conditions
Takeaways linked to increased cardiovascular risk factors and obesity in children Signal - Takeaways linked to increased cardiovascular risk factors and obesity in children Dissemination Centre Discover Portal NIHR DC Discover Takeaways linked to increased cardiovascular risk factors and obesity in children Published on 13 February 2018 Children who eat takeaways once or more each week have more body fat and higher low-density lipoprotein (LDL) “bad” cholesterol levels than those who never (...) or hardly ever eat them. Their diets were also higher in fat and lower in protein and calcium. This cross-sectional study looked in depth at eating habits and risk markers for coronary heart disease, obesity and diabetes in 2,529 children in England. Though this type of study can only show an association between takeaways and risk markers, it is one of the first of its type, and the results do give cause for concern. Increasing numbers of people are eating takeaways in the UK. Local authorities
Weight loss surgery is value for money in selected people with severe obesity Signal - Weight loss surgery is value for money in selected people with severe obesity Dissemination Centre Discover Portal NIHR DC Discover Weight loss surgery is value for money in selected people with severe obesity Published on 23 August 2016 Surgery is a cost-effective method of weight loss for severely and morbidly obese people. This study of general practice data compared health costs and outcomes for people (...) with severe or morbid obesity who underwent surgery and those who did not. Surgery was associated with a reduced chance of developing diabetes and an increased chance of remission in people with diabetes. It was more cost-effective – using NHS thresholds – for morbidly obese people who had diabetes, than for those without diabetes. Weight loss surgery either reduces the amount of food people can consume or the amount of energy they can absorb from food. A quarter of UK adults are obese, with 3.6% of women
Resistance training may prevent obese older people becoming frail when losing weight Signal - Resistance training may prevent obese older people becoming frail when losing weight Dissemination Centre Discover Portal NIHR DC Discover Resistance training may prevent obese older people becoming frail when losing weight Published on 29 August 2017 Combining resistance training with aerobic exercise increased physical function in older, obese adults who were following a weight loss programme (...) . Functional improvements, such as the speed to stand from a chair or to climb stairs, were greater with combination training (21%) than with either type of exercise performed alone (14%). This randomised controlled trial assigned 160 obese adults in the USA (aged over 65, mostly educated white females) to the different types of exercise for six months. Those exercising lost about 9% body weight on their diets. Resistance training was most effective for preventing loss of muscle and bone mass. This
Intensive lifestyle interventions can help obese young people lose weight Signal - Intensive lifestyle interventions can help obese young people lose weight Dissemination Centre Discover Portal NIHR DC Discover Intensive lifestyle interventions can help obese young people lose weight Published on 19 September 2017 Obese children and adolescents can lose up to seven pounds over six to 12 months when they engage in at least 52 hours of behaviour-based lifestyle interventions. Minimal benefit (...) was seen with shorter contact time, with less than 25 hours ineffective. The control group gained weight. Rising obesity in the young is a global concern, which may lead to high rates of obesity-related diseases in adulthood. This review identified trials covering various weight management strategies. Lifestyle-based-interventions with sufficient contact time – as recommended by UK guidelines – showed clear benefits with no evidence of harms. Investing in effective strategies to manage child obesity
Being overweight or obese is linked with heart disease even without other metabolic risk factors Signal - Being overweight or obese is linked with heart disease even without other metabolic risk factors Dissemination Centre Discover Portal NIHR DC Discover Being overweight or obese is linked with heart disease even without other metabolic risk factors Published on 7 November 2017 People with certain metabolic risk factors who are obese are two and a half times as likely to develop heart disease (...) as healthy people of normal weight. But those who are obese without these other risk factors still have a 28% increased risk of heart disease compared with healthy people of normal weight. This suggests excess weight should be seen as an independent risk factor, challenging the idea that people can be “fat but fit”. Metabolic risk factors for heart disease cluster together and in this large study the researchers defined “metabolically healthy” as not having; high blood pressure, raised blood sugar, high
A school-based obesity prevention programme was ineffective A school-based obesity prevention programme was ineffective Dissemination Centre Discover Portal NIHR DC Discover A school-based obesity prevention programme was ineffective Published on 10 April 2018 A school-based healthy lifestyle programme delivered to 6-7-year-old children and their parents made no difference to children’s weight, diet or activity levels. Around 1 in 4 remained overweight or obese. The NIHR-funded year-long (...) programme was delivered in 54 primary schools in one region of England. Teachers were trained to provide an additional 30 minutes of physical activity a day and deliver cookery workshops with parents each term. It also included activities with a local football club, Aston Villa. Children in schools that took part were no less likely to be overweight or obese after 15 or 30 months, and their diet and exercise levels did not improve. Less than one in six schools managed to deliver the activity sessions
Obesity in children Obesity in children - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search Obesity in children Last reviewed: December 2018 Last updated: January 2019 Summary Behavioural and environmental factors are primarily responsible for the dramatic increase in obesity in the past two decades, although genes play an important role in regulation of body weight. Calculating body mass index (BMI) is the most widely (...) accepted method of screening for obesity in children. Abnormal BMI cut-offs in children are determined by age- and sex-specific percentiles. The dramatic increase in childhood obesity has led to a marked increase in the diagnosis of impaired glucose tolerance and type 2 diabetes mellitus in children. Preventing excessive weight gain in children is of paramount importance in confronting the obesity epidemic, as obesity is difficult to treat at all ages, and obese children tend to become obese adults
Ethical Considerations for the Care of Patients With Obesity Ethical Considerations for the Care of Patients With Obesity - ACOG Menu ▼ Ethical Considerations for the Care of Patients With Obesity Page Navigation ▼ Number 763 (Replaces Committee Opinion Number 600, June 2014) Committee on Ethics This Committee Opinion was developed by the American College of Obstetricians and Gynecologists’ Committee on Ethics in collaboration with committee members Sigal Klipstein, MD, and Ginny L. Ryan, MD (...) and Gynecologists has neither solicited nor accepted any commercial involvement in the development of the content of this published product. Ethical Considerations for the Care of Patients With Obesity ABSTRACT: Obesity is a medical condition that may be associated with bias among health care professionals, and this bias may result in disrespectful or inadequate care of patients with obesity. Obstetrician–gynecologists regularly care for patients with obesity and play an integral role in advocating for best
Does Prior Bariatric Surgery Improve Outcomes Following Total Joint Arthroplasty in the Morbidly Obese? A Meta-Analysis 30528132 2018 12 11 1532-8406 2018 Nov 20 The Journal of arthroplasty J Arthroplasty Does Prior Bariatric Surgery Improve Outcomes Following Total Joint Arthroplasty in the Morbidly Obese? A Meta-Analysis. S0883-5403(18)31145-8 10.1016/j.arth.2018.11.018 There remains a controversy regarding the risks in subsequent total joint arthroplasty (TJA) with and without previous (...) was defined as that from hospital discharge to 90 days, and long-term follow-up was defined as more than 1 year. A total of 9 studies with 38,728 patients were included. Overall, medical comorbidities were higher in the BS group compared with the control morbid obesity group before TJA. Our meta-analysis revealed that BS prior to TJA was associated with reduced short-term medical complications, length of stay, and operative time. However, BS did not reduce the short-term risks for superficial wound
Weight loss surgery for obesity can lead to substantial weight loss and improved health outcomes Signal - Weight loss surgery for obesity can lead to substantial weight loss and improved health outcomes Dissemination Centre Discover Portal NIHR DC Discover Weight loss surgery for obesity can lead to substantial weight loss and improved health outcomes Published on 9 February 2016 On average people lost 5 kg more in each of the first four months after weight loss surgery than those of a similar (...) weight who did not undergo surgery. The risks of developing type 2 diabetes and high blood pressure were reduced. Surgery was linked to reduced risk of heart disease and sleep-related breathing problems. Those entering the trial had an average BMI of 44.7 kg/m2. Rates of obesity are high in the UK, around a quarter of the adult population is obese, and rising every year. Obesity is linked with health conditions such as type 2 diabetes, which is expensive to manage and has a big impact on people’s
Effect of weight reduction on severity of lower urinary tract symptoms in obese men with benign prostatic hyperplasia. 29938670 2018 12 11 2018 12 11 1024-2708 23 Suppl 2 3 2017 06 Hong Kong medical journal = Xianggang yi xue za zhi Hong Kong Med J Effect of weight reduction on severity of lower urinary tract symptoms in obese men with benign prostatic hyperplasia. 35-37 Ng C F CF Division of Urology, Department of Surgery, The Chinese University of Hong Kong. Yee C H CH Division of Urology (...) Urinary Tract Symptoms drug therapy Male Middle Aged Obesity Prospective Studies Prostatic Hyperplasia drug therapy Severity of Illness Index Weight Loss 2018 6 26 6 0 2018 6 26 6 0 2018 12 12 6 0 ppublish 29938670
Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404) Sorry - the page you requested could not be found. Please choose a page from
Care of Women with Obesity in Pregnancy Care of Women with Obesity in Pregnancy Green-top Guideline No. 72 November 2018 Please cite this paper as: Denison FC, Aedla NR, Keag O, Hor K, Reynolds RM, Milne A, Diamond A, on behalf of the Royal College of Obstetricians and Gynaecologists. Care of Women with Obesity in Pregnancy. Green-top Guideline No. 72. BJOG 2018; https://doi.org/10.1111/1471-0528.15386.000:1–45.DOI: 10.1111/1471-0528.15386 RCOG Green-top Guidelines Care of Women with Obesity (...) in Pregnancy FC Denison, NR Aedla, O Keag, K Hor, RM Reynolds, A Milne, A Diamond, on behalf of the Royal College of Obstetricians and Gynaecologists Correspondence: Royal College of Obstetricians and Gynaecologists, 27 Sussex Place, Regent’s Park, London NW1 4RG. Email: email@example.com This is the second edition of this guideline. The ?rst edition was published in 2010 as a joint guideline with the Centre of Maternal and Child Enquiries under the title ‘Management of Women with Obesity
Motivational Interviewing to Treat Adolescents With Obesity: A Meta-analysis 30348753 2018 11 03 1098-4275 142 5 2018 Nov Pediatrics Pediatrics Motivational Interviewing to Treat Adolescents With Obesity: A Meta-analysis. e20180733 10.1542/peds.2018-0733 Successful treatment approaches are needed for obesity in adolescents. Motivational interviewing (MI), a counseling approach designed to enhance behavior change, shows promise in promoting healthy lifestyle changes. Conduct a systematic review (...) of MI for treating overweight and obesity in adolescents and meta-analysis of its effects on anthropometric and cardiometabolic outcomes. We searched Medline, Embase, Cumulative Index to Nursing and Allied Health Literature, PsychINFO, Web of Science, Cochrane Library, and Google Scholar from January 1997 to April 2018. Four authors reviewed titles, abstracts, and full-text articles. Two authors abstracted data and assessed risk of bias and quality of evidence. Seventeen studies met inclusion