Latest & greatest articles for nsaids

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Top results for nsaids

101. NSAID use selectively increases the risk of non-fatal myocardial infarction: a systematic review of randomised trials and observational studies

NSAID use selectively increases the risk of non-fatal myocardial infarction: a systematic review of randomised trials and observational studies Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2011 DARE.

102. Cardiovascular and Gastrointestinal Safety of NSAIDs: A Systematic Review of Meta-Analyses of Randomized Clinical Trials Full Text available with Trip Pro

Cardiovascular and Gastrointestinal Safety of NSAIDs: A Systematic Review of Meta-Analyses of Randomized Clinical Trials As part of the Safety of Non-Steroidal Anti-Inflammatory Drugs (SOS) Project, we reviewed the incidence of cardiovascular (CV) and gastrointestinal (GI) events associated with the use of this category of drugs. We collected data from published meta-analyses (MAs) of clinical trials of nonsteroidal anti-inflammatory drugs (NSAIDs). The Medline, Cochrane, ISI, and SCOPUS (...) databases were systematically searched for MAs of NSAID clinical trials that could potentially contain data on adverse incidents such as myocardial infarction (MI), cerebrovascular events (CeVs), stroke, thromboembolic events (ThEs), heart failure (HF), gastrointestinal bleeding (GIB), and perforation, ulcer, and bleeding (PUB). From 1,733 identified references, 29 MAs were selected for the review. This allowed 109 estimations of incidence rates of CV adverse events and 26 estimations of incidence rates

2011 EvidenceUpdates

103. Colchicine as an adjunct to NSAIDs for the treatment of acute pericarditis

Colchicine as an adjunct to NSAIDs for the treatment of acute pericarditis BestBets: Colchicine as an adjunct to NSAIDs for the treatment of acute pericarditis Colchicine as an adjunct to NSAIDs for the treatment of acute pericarditis Report By: Alex Eppert - Emergency Medicine Resident Search checked by Janos P Baombe - Senior Emergency Trainee Institution: Grand Rapid Medical Education and Research Center, Michigan State University, Michigan, US and Manchester Royal Infirmary, Manchester, UK (...) Date Submitted: 6th June 2006 Date Completed: 9th March 2011 Last Modified: 10th March 2011 Status: Green (complete) Three Part Question In [adult patients with a first episode of acute pericarditis] is [colchicine plus NSAIDs better than NSAIDSs alone] at [relieving pain and preventing recurrence]? Clinical Scenario A 32-year-old woman with no significant medical history presents to the emergency department with chest pain and dyspnoea. A pericardial friction rub is heard on examination. The ECG

2011 BestBETS

104. Should You Eradicate Helicobacter Pylori Prior to Chronic NSAID Treatment?

Should You Eradicate Helicobacter Pylori Prior to Chronic NSAID Treatment? Should You Eradicate Helicobacter Pylori Prior to Chronic NSAID Treatment? – Clinical Correlations Search Should You Eradicate Helicobacter Pylori Prior to Chronic NSAID Treatment? January 19, 2011 4 min read By Joshua Smith, MD Faculty Peer Reviewed CASE: A 54-year-old Asian female with no significant past medical history presents to her primary care physician with the complaint of several weeks of pain in her fingers (...) bilaterally along with pronounced, worsening morning stiffness. She is subsequently diagnosed with rheumatoid arthritis (RA), and the decision is made to start her on long-term, high-dose non-steroidal anti-inflammatory drugs (NSAIDs). Given the link between NSAIDs and peptic ulcer disease (PUD), should this patient first be tested, and if positive, treated for Helicobacter pylori (H. pylori) ? It has been widely recognized that infection with H. pylori predisposes individuals to PUD as well as gastric

2011 Clinical Correlations

105. Should Topical NSAIDs Be Used to Treat Acute Musculoskeletal Conditions?

Should Topical NSAIDs Be Used to Treat Acute Musculoskeletal Conditions? SystematicReviewSnapshot ClinicalSynopsis TAKE-HOME MESSAGE Topical nonsteroidal anti-in?ammatory drugs effectively reduce pain associated with musculoskeletal conditions compared with placebo, with fewer adverse events compared with oral nonsteroidal anti-in?ammatory drugs. METHODS DATA SOURCES The authors searched the Cochrane Central Register of Controlled Trials (CENTRAL) (Cochrane Library, 2009, issue 4), MEDLINE (...) the list of those included in this review. 7 This Cochrane review demonstrated that topical non- steroidal anti-in?ammatory drugs, com- pared with placebo, provide adequate Performance of topical nonsteroidal anti-in?ammatory drugs versus placebo in acute musculoskeletal injuries. Studies (Total No. of Patients) Treatment Bene?t,* RR (95% CI) Adverse Event, † RR (95% CI) I 2 ,% Topical NSAID vs placebo 31 (3,462) 1.5 (1.4–1.6) 1.1 (0.88–1.4) 74 RR, Relative risk; CI, con?dence interval; NSAID

2011 Annals of Emergency Medicine Systematic Review Snapshots

106. Systematic review with meta-analysis: NSAID use associated with increased cardiovascular risk and death, but naproxen appears to be the least harmful

Systematic review with meta-analysis: NSAID use associated with increased cardiovascular risk and death, but naproxen appears to be the least harmful NSAID use associated with increased cardiovascular risk and death, but naproxen appears to be the least harmful | BMJ Evidence-Based Medicine We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see (...) our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here NSAID use associated with increased cardiovascular risk and death, but naproxen appears to be the least harmful Article Text

2011 Evidence-Based Medicine

107. Stroke risk and NSAIDs: a systematic review of observational studies

Stroke risk and NSAIDs: a systematic review of observational studies Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2011 DARE.

108. NSAIDs vs acetaminophen in knee and hip osteoarthritis: a systematic review regarding heterogeneity influencing the outcomes

NSAIDs vs acetaminophen in knee and hip osteoarthritis: a systematic review regarding heterogeneity influencing the outcomes Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2011 DARE.

109. Systematic review of randomised controlled trials: Only a small reduction in morphine use with adding NSAIDs, paracetamol or COX-2 inhibitors to patient controlled morphine in the 24 h after major surgery

Systematic review of randomised controlled trials: Only a small reduction in morphine use with adding NSAIDs, paracetamol or COX-2 inhibitors to patient controlled morphine in the 24 h after major surgery Only a small reduction in morphine use with adding NSAIDs, paracetamol or COX-2 inhibitors to patient controlled morphine in the 24 h after major surgery | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie (...) with adding NSAIDs, paracetamol or COX-2 inhibitors to patient controlled morphine in the 24 h after major surgery Article Text Pain management Systematic review of randomised controlled trials Only a small reduction in morphine use with adding NSAIDs, paracetamol or COX-2 inhibitors to patient controlled morphine in the 24 h after major surgery Hance Clarke Statistics from Altmetric.com Commentary on: McDaid C , Maund E , Rice S , et al . Paracetamol and selective and non-selective non-steroidal anti

2011 Evidence-Based Nursing

110. Cochrane systematic review: Topical NSAIDs provide effective relief of acute musculoskeletal pain compared to placebo, with no increase in risk of adverse effects

Cochrane systematic review: Topical NSAIDs provide effective relief of acute musculoskeletal pain compared to placebo, with no increase in risk of adverse effects Topical NSAIDs provide effective relief of acute musculoskeletal pain compared to placebo, with no increase in risk of adverse effects | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about (...) how we use cookies, please see our . Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Topical NSAIDs provide effective relief of acute musculoskeletal pain compared to placebo

2011 Evidence-Based Nursing

111. Evaluation of the treatment effect of NSAIDs/TNF blockers according to different domains in ankylosing spondylitis: results of a meta-analysis Full Text available with Trip Pro

Evaluation of the treatment effect of NSAIDs/TNF blockers according to different domains in ankylosing spondylitis: results of a meta-analysis To assess the treatment effect of NSAIDs and TNF blockers in AS according to different domains of interest.A systematic literature research was performed in electronic databases up to October 2009. All randomized controlled trials (RCTs) reporting the efficacy (on pain and/or physical function and/or acute-phase reactants) of NSAIDs/anti-TNF vs placebo (...) in AS were selected. Pooled effect sizes were calculated by meta-analysis, using fixed or random-effect models.Optimal data to calculate the effect size were available in 8 out of the 240 selected RCTs evaluating anti-TNF and 5 of the 135 evaluating NSAIDs. For the domains pain, physical function and patient's global assessment, the treatment effect was large or medium for both TNF blockers and NSAIDs. For the domain acute-phase reactants, the effect of TNF blockers was medium [standardized mean

2010 EvidenceUpdates

112. Medications (NSAIDs, statins, proton pump inhibitors) and the risk of esophageal adenocarcinoma in patients with Barrett`s esophagus Full Text available with Trip Pro

Medications (NSAIDs, statins, proton pump inhibitors) and the risk of esophageal adenocarcinoma in patients with Barrett`s esophagus Limited evidence suggests that proton pump inhibitors (PPI), nonsteroidal anti-inflammatory drugs (NSAID)/aspirin, and statins may be associated with a low risk of esophageal neoplasia. However, the possible effect these medications may have on the risk of esophageal adenocarcinoma (EAC) in patients with existing Barrett's esophagus (BE) is unclear.We conducted (...) a nested case-control study in a cohort of patients with BE identified in the national Department of Veterans' Affairs computerized databases. Cases with incident EAC were matched by incidence density sampling to controls with BE who remained without EAC at the date of the EAC diagnosis for the corresponding case. We identified prescriptions for PPI, NSAIDs/aspirin, and statins that were filled between BE diagnosis and EAC diagnosis. Incidence density ratios were calculated using conditional logistic

2010 EvidenceUpdates

113. ACCF/ACG/AHA 2010 Expert Consensus Document on the Concomitant Use of Proton Pump Inhibitors and Thienopyridines: A Focused Update of the ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID

ACCF/ACG/AHA 2010 Expert Consensus Document on the Concomitant Use of Proton Pump Inhibitors and Thienopyridines: A Focused Update of the ACCF/ACG/AHA 2008 Expert Consensus Document on Reducing the Gastrointestinal Risks of Antiplatelet Therapy and NSAID nature publishing group the red section 2533 Writing Committee Members Neena S. Abraham, MD, FACG, Chair*; Mark A. Hlatky, MD, FACC, FAHA, Vice Chair† Elliott M. Antman, MD, FACC, FAHA‡; Deepak L. Bhatt, MD, MPH, FACC, FAHA† David J. Bjorkman (...) KW , Quigley EM, Scheiman J, Sper - ling LS, Tomaselli GF (. ACCF/ACG/AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. Am J Gastroenterol 2010;105:2533–2549; doi:10.1038/ajg.2010.445. This article has been copublished in the Journal of the American College of Cardiology and Circulation. Copies

2010 American College of Gastroenterology

114. Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDs in the treatment of ankylosing spondylitis

Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDs in the treatment of ankylosing spondylitis Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDs in the treatment of ankylosing spondylitis Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDs in the treatment of ankylosing spondylitis Jansen JP, Gaugris S, Choy EH, Ostor A, Nash JT, Stam W Record Status This is a critical abstract of an economic evaluation that meets (...) the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment on the reliability of the study and the conclusions drawn. CRD summary This study evaluated the cost-effectiveness of etoricoxib compared with celecoxib, diclofenac, and naproxen for patients with ankylosing spondylitis, who required routine non-steroidal anti-inflammatory drug (NSAID) treatment. The authors concluded that their economic

2010 NHS Economic Evaluation Database.

115. Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review

Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side-effects after major surgery: a systematic review Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side (...) -effects after major surgery: a systematic review McDaid C, Maund E, Rice S, Wright K, Jenkins B, Woolacott N Record Status This is a bibliographic record of a published health technology assessment from a member of INAHTA. No evaluation of the quality of this assessment has been made for the HTA database. Citation McDaid C, Maund E, Rice S, Wright K, Jenkins B, Woolacott N. Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related

2010 Health Technology Assessment (HTA) Database.

116. Systematic review: NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects

Systematic review: NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects | Evidence-Based Nursing We use cookies to improve our service and to tailor our content and advertising to you. You can manage your cookie settings via your browser at any time. To learn more about how we use cookies, please see our . Log in using your (...) username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here NSAIDs similarly effective to acetaminophen plus codeine for post-laparotomy pain and may reduce adverse effects Article Text Therapeutics Systematic

2010 Evidence-Based Nursing

117. Effectiveness and tolerability of NSAIDs in the prophylaxis of pancreatitis after endoscopic retrograde cholangiopancreatography: a systematic review and meta-analysis

Effectiveness and tolerability of NSAIDs in the prophylaxis of pancreatitis after endoscopic retrograde cholangiopancreatography: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

118. Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis

Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 NHS Economic Evaluation Database.

119. NSAID use and the risk of Parkinson's disease: systematic review and meta-analysis of observational studies

NSAID use and the risk of Parkinson's disease: systematic review and meta-analysis of observational studies Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.

120. Association between NSAIDs use and breast cancer risk: a systematic review and meta-analysis

Association between NSAIDs use and breast cancer risk: a systematic review and meta-analysis Untitled Document The CRD Databases will not be available from 08:00 BST on Friday 4th October until 08:00 BST on Monday 7th October for essential maintenance. We apologise for any inconvenience.

2009 DARE.