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Top results for nsaids

21. Safety considerations for NSAIDs

Safety considerations for NSAIDs Vol 24. DTB: Vol 24, No 2 - navarra.es Castellano | Euskara | Français | English Use the search tool! Search engine : : : : : : : : DTB: Vol 24, No 2 DTB: Vol 24, No 2 Content tools Share it Safety considerations for NSAIDs The gastrointestinal, cardiovascular, and renal adverse effects of NSAIDs are related to the total daily dose and may appear less than 15 days from the start of treatment. The safest NSAIDs are ibuprofen and naproxen, whether used alone (...) . Although gastrointestinal risk can be countered using gastric protectors, there is no concomitant drug therapy for cardiovascular risk. The results of this review reveal an overuse of celecoxib and etoricoxib in Navarre. NSAIDs in combination with proton pump inhibitors (PPIs) should be used with caution, since PPIs are not indicated for all patients requiring NSAIDs. Furthermore, the combination of these drugs may result in incorrect dosages. Authors: Isabel Aranguren. Pharmacist. Navarre Health

Drug and Therapeutics Bulletin of Navarre (Spain)2016

22. Can topical NSAIDs help relieve the pain of arthritis?

Can topical NSAIDs help relieve the pain of arthritis? Can topical NSAIDs help relieve the pain of arthritis? - Evidently Cochrane Search and hit Go By May 6, 2016 // A blog for non-medical readers by Lynda Ware, Senior Fellow in General Practice with Cochrane UK. “Just put some cream on it….” According to my three daughters, this was my stock response to any request they made for motherly intervention when pain struck. Whilst refuting this slur utterly (and the one about not even looking), I (...) might now point them in the direction of this updated review, which assesses the efficacy and safety of topical nonsteroidal anti-inflammatory drugs (NSAIDs), albeit in the context of chronic musculoskeletal pain rather than a bruised shin or finger. What’s more, I will point out that it’s likely that the carrier, to which the active drug is added, is pretty effective in its own right. Why is this important? Topical NSAIDs can act precisely where needed and without having to be absorbed via

Evidently Cochrane2016

23. Can topical NSAIDs help relieve the pain of arthritis?

Can topical NSAIDs help relieve the pain of arthritis? Can topical NSAIDs help relieve the pain of arthritis? - Evidently Cochrane Search and hit Go By May 6, 2016 // A blog for non-medical readers by Lynda Ware, Senior Fellow in General Practice with Cochrane UK. “Just put some cream on it….” According to my three daughters, this was my stock response to any request they made for motherly intervention when pain struck. Whilst refuting this slur utterly (and the one about not even looking), I (...) might now point them in the direction of this updated review, which assesses the efficacy and safety of topical nonsteroidal anti-inflammatory drugs (NSAIDs), albeit in the context of chronic musculoskeletal pain rather than a bruised shin or finger. What’s more, I will point out that it’s likely that the carrier, to which the active drug is added, is pretty effective in its own right. Why is this important? Topical NSAIDs can act precisely where needed and without having to be absorbed via

Evidently Cochrane2016

24. Pregabalin in Patients With Painful Diabetic Peripheral Neuropathy Using an NSAID for Other Pain Conditions: A Double-Blind Crossover Study

Pregabalin in Patients With Painful Diabetic Peripheral Neuropathy Using an NSAID for Other Pain Conditions: A Double-Blind Crossover Study 25968451 2016 02 06 2016 10 27 2016 12 30 1536-5409 32 3 2016 Mar The Clinical journal of pain Clin J Pain Pregabalin in Patients With Painful Diabetic Peripheral Neuropathy Using an NSAID for Other Pain Conditions: A Double-Blind Crossover Study. 203-10 10.1097/AJP.0000000000000254 To evaluate pregabalin's efficacy and safety versus placebo to reduce pain (...) in patients with diabetic peripheral neuropathy (DPN) using a concomitant nonsteroidal anti-inflammatory drug. In a randomized, double-masked, 14-week, 2-period, crossover study, patients with painful DPN using a nonsteroidal anti-inflammatory drug for non-DPN-related pain received 150 to 300 mg/d pregabalin or placebo (period 1); 14-day washout; then, the opposite therapy (period 2). Endpoints included weekly change in DPN pain score, sleep interference, adverse events, and patient-reported outcomes

EvidenceUpdates2016

25. Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen

Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen Prescrire IN ENGLISH - Spotlight ''Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen'', 1 January 2016 {1} {1} {1} | | > > > Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |  (...)  |   |   |   |   |   |   |  Spotlight Nonsteroidal anti-inflammatory drugs (NSAIDs): avoid cox-2 inhibitors, diclofenac and high-dose ibuprofen When pain medication is required, paracetamol (alias acetaminophen) is the reference drug. Among the nonsteroidal anti-inflammatories (NSAIDs), naproxen or ibuprofen (not exceeding 1200 mg a day) are the drugs that carry the least exposure to cardiac disorders. When pain medication is needed

Prescrire2016

26. Systematic review: Topical NSAIDs significantly reduces pain in adults with acute musculoskeletal injuries

Systematic review: Topical NSAIDs significantly reduces pain in adults with acute musculoskeletal injuries Topical NSAIDs significantly reduces pain in adults with acute musculoskeletal injuries | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search (...) for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Topical NSAIDs significantly reduces pain in adults with acute musculoskeletal injuries Article Text Therapeutics/Prevention Systematic review Topical NSAIDs significantly reduces pain in adults with acute musculoskeletal injuries Gwendolyn Vuurberg 1 , 2 , 3 , Gino M M J Kerkhoffs 1 , 2 , 3 Statistics from Altmetric.com

Evidence-Based Medicine (Requires free registration)2016

27. Systematic review: No difference in pain, swelling or function with NSAIDs compared with paracetamol for soft tissue injury

Systematic review: No difference in pain, swelling or function with NSAIDs compared with paracetamol for soft tissue injury No difference in pain, swelling or function with NSAIDs compared with paracetamol for soft tissue injury | Evidence-Based Nursing This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password (...) ? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here No difference in pain, swelling or function with NSAIDs compared with paracetamol for soft tissue injury Article Text Pain management Systematic review No difference in pain, swelling or function with NSAIDs compared with paracetamol for soft tissue injury Michel P J van den Bekerom

Evidence-Based Nursing (Requires free registration)2016

28. Randomised controlled trial: NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent?

Randomised controlled trial: NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent? NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent? | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts (...) Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here NSAIDs or paracetamol for short-term treatment of mild to moderate knee pain in early osteoarthritis: are they equivalent? Article Text Therapeutics/Prevention Randomised controlled trial NSAIDs or paracetamol for short-term treatment

Evidence-Based Medicine (Requires free registration)2016

29. NSAIDs: Inflamed effects on inflammation?

NSAIDs: Inflamed effects on inflammation? Tools for Practice is proudly sponsored by the Alberta College of Family Physicians (ACFP). ACFP is a provincial, professional voluntary organization, representing more than 4,000 family physicians, family medicine residents and medical students in Alberta. Established over fifty years ago, the ACFP strives for excellence in family practice through advocacy, continuing medical education and primary care research. www.acfp.ca March 29, 2016 NSAIDs (...) : Inflamed effects on inflammation? Clinical Question: Do non-steroidal anti-inflammatory drugs (NSAIDs) reduce swelling and inflammation in acute injury? Bottom Line: Randomized Controlled Trials (RCTs) of NSAIDs effect on musculoskeletal injury swelling show highly inconsistent results: Some slight improvements (2-11%), some slight worsening (8%) and most no effect. It is unlikely NSAIDs have any reliable effect on acute injury swelling but they do improve pain for ~1 in 4 over one week. Evidence

Tools for Practice2016

30. Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clinical Trial.

Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clinical Trial. 26720026 2016 01 01 2016 02 01 2016 11 22 1538-3598 314 24 2015 Dec 22-29 JAMA JAMA Effect of Opioids vs NSAIDs and Larger vs Smaller Chest Tube Size on Pain Control and Pleurodesis Efficacy Among Patients With Malignant Pleural Effusion: The TIME1 Randomized Clinical Trial. 2641-53 10.1001/jama.2015.16840 (...) For treatment of malignant pleural effusion, nonsteroidal anti-inflammatory drugs (NSAIDs) are avoided because they may reduce pleurodesis efficacy. Smaller chest tubes may be less painful than larger tubes, but efficacy in pleurodesis has not been proven. To assess the effect of chest tube size and analgesia (NSAIDs vs opiates) on pain and clinical efficacy related to pleurodesis in patients with malignant pleural effusion. A 2×2 factorial phase 3 randomized clinical trial among 320 patients requiring

JAMA2015 Full Text: Link to full Text with Trip Pro

31. For Patients Undergoing Open-Flap Debridement Surgery, There is No Significant Difference Between Dexamethasone and NSAIDs For Reducing Patient Perceived Pain

For Patients Undergoing Open-Flap Debridement Surgery, There is No Significant Difference Between Dexamethasone and NSAIDs For Reducing Patient Perceived Pain UTCAT2956, Found CAT view, CRITICALLY APPRAISED TOPICs University: | | ORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAM View the CAT / Title For Patients Undergoing Open-Flap Debridement Surgery, There is No Significant Difference Between Dexamethasone and NSAIDs For Reducing Patient Perceived Pain Clinical Question In adults undergoing (...) periodontal surgery, what is the effect of dexamethasone on patient perceived pain as compared to traditional non-steroidal anti-inflammatories? Clinical Bottom Line Dexamethasone and NSAIDs are equally effective in reducing patient perceived pain following periodontal open flap debridement surgeries. Best Evidence (you may view more info by clicking on the PubMed ID link) PubMed ID Author / Year Patient Group Study type (level of evidence) #1) Steffens/2010 15 adult patients receiving periodontal surgery

UTHSCSA Dental School CAT Library2015

32. Topical NSAIDs: good relief for acute musculoskeletal pain

Topical NSAIDs: good relief for acute musculoskeletal pain Topical NSAIDs: good relief for acute musculoskeletal pain - Evidently Cochrane Search and hit Go By June 25, 2015 // Non-steroidal anti-inflammatory drugs (NSAIDs) are routinely prescribed for mild to moderate pain and are the most commonly prescribed painkilling drugs worldwide. Taken by mouth or injected into a vein, the high concentrations of the drug throughout the body, necessary in order to work at the site of pain (...) and inflammation, can cause unpleasant or even serious side effects. Applied to the skin, so in a topical preparation such as a gel, cream or plaster, they can act where needed to relieve pain without affecting the rest of the body. For superficial painful conditions like sprains, strains and muscle soreness (and where the skin is unbroken) topical NSAIDs offer this clear advantage over taking tablets, as long as they work. How good are topical NSAIDs? A has been updated with new research confirming

Evidently Cochrane2015

33. Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants.

Association of aspirin and NSAID use with risk of colorectal cancer according to genetic variants. IMPORTANCE: Use of aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with lower risk of colorectal cancer. OBJECTIVE: To identify common genetic markers that may confer differential benefit from aspirin or NSAID chemoprevention, we tested gene × environment interactions between regular use of aspirin and/or NSAIDs and single-nucleotide polymorphisms (SNPs) in relation (...) to risk of colorectal cancer. DESIGN, SETTING, AND PARTICIPANTS: Case-control study using data from 5 case-control and 5 cohort studies initiated between 1976 and 2003 across the United States, Canada, Australia, and Germany and including colorectal cancer cases (n=8634) and matched controls (n=8553) ascertained between 1976 and 2011. Participants were all of European descent. EXPOSURES: Genome-wide SNP data and information on regular use of aspirin and/or NSAIDs and other risk factors. MAIN OUTCOMES

JAMA2015 Full Text: Link to full Text with Trip Pro

34. Corticosteroid Injections Accelerate Pain Relief and Recovery of Function Compared With Oral NSAIDs in Patients With Adhesive Capsulitis: A Randomized Controlled Trial

Corticosteroid Injections Accelerate Pain Relief and Recovery of Function Compared With Oral NSAIDs in Patients With Adhesive Capsulitis: A Randomized Controlled Trial 26657263 2016 02 02 2016 09 19 2016 02 02 1552-3365 44 2 2016 Feb The American journal of sports medicine Am J Sports Med Corticosteroid Injections Accelerate Pain Relief and Recovery of Function Compared With Oral NSAIDs in Patients With Adhesive Capsulitis: A Randomized Controlled Trial. 474-81 10.1177/0363546515616238 Intra (...) nonsteroidal anti-inflammatory drugs (NSAIDs) and physical therapy. Randomized controlled trial; Level of evidence, 1. A total of 74 patients with primary adhesive capsulitis in the freezing stage were randomized to receive either intra-articular injections with betamethasone or oral NSAIDs. Clinical outcome was documented at baseline and after 2, 4, 8, and 12 weeks and comprised a visual analog scale (VAS) for pain, the American Shoulder and Elbow Surgeons (ASES) Shoulder Score, the abbreviated Constant-Murley score

EvidenceUpdates2015

35. Nonsteroidal anti-inflammatory drugs (NSAIDs) and risk for bleeding after gastrointestinal surgery

Nonsteroidal anti-inflammatory drugs (NSAIDs) and risk for bleeding after gastrointestinal surgery Nonsteroidal anti-inflammatory drugs (NSAIDs) and risk for bleeding after gastrointestinal surgery We use cookies on this website. By using this site, you agree that we may store and access cookies on your device. Swedish Agency for Health Technology Assessment and Assessment of Social Services Nonsteroidal anti-inflammatory drugs (NSAIDs) and risk for bleeding after gastrointestinal surgery Share (...) : Reading time approx. 7 minutes NSAIDs are a class of drugs that are anti-inflammatory, analgesic and antipyretic but which also leads to an increased risk of bleeding. This is a response from the SBU’s Enquiry Service November 11, 2015. Disclaimer: Responses from SBU’s Enquiry Service presents conclusions solely as interpreted by the authors of the individual studies included. SBU’s Enquiry Service makes no attempt to combine or interpret the body of evidence, as there has been no formal quality

Swedish Council on Technology Assessement2015

36. Cohort study: NSAIDs increase bleeding risk in patients with atrial fibrillation on antithrombotic therapy

Cohort study: NSAIDs increase bleeding risk in patients with atrial fibrillation on antithrombotic therapy NSAIDs increase bleeding risk in patients with atrial fibrillation on antithrombotic therapy | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword (...) Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here NSAIDs increase bleeding risk in patients with atrial fibrillation on antithrombotic therapy Article Text Aetiology/Harm Cohort study NSAIDs increase bleeding risk in patients with atrial fibrillation on antithrombotic therapy Emer R McGrath Statistics from Altmetric.com No Altmetric data available

Evidence-Based Medicine (Requires free registration)2015

37. Cohort study: In infants born extremely preterm, aspirin or NSAID use during pregnancy are associated with increased risk of quadriparetic cerebral palsy

Cohort study: In infants born extremely preterm, aspirin or NSAID use during pregnancy are associated with increased risk of quadriparetic cerebral palsy In infants born extremely preterm, aspirin or NSAID use during pregnancy are associated with increased risk of quadriparetic cerebral palsy | Evidence-Based Nursing This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in via your Society Log in using your username and password For personal (...) accounts OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in via your Society Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here In infants born extremely preterm, aspirin or NSAID use during pregnancy are associated with increased risk of quadriparetic cerebral palsy Article Text Child health

Evidence-Based Nursing (Requires free registration)2014

38. NSAIDs

NSAIDs USE OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) IN PREGNANCY 0344 892 0909 USE OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs) IN PREGNANCY (Date of issue: August 2014 , Version: 2 ) This is a UKTIS monograph for use by health care professionals. For case-specific advice please contact UKTIS on 0344 892 0909. To report an exposure please download and complete a . Please encourage all women to complete an . Summary Non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat (...) pain and inflammation in various disease states. NSAID use in pregnancy has been associated with increased risks of various different congenital malformations, including cardiovascular defects and oral clefts, as well as an increased risk of spontaneous abortion. However, the available data are conflicting and limited, and firm associations are yet to be concluded. The available data on NSAID use in pregnancy does not suggest an association with stillbirth, low infant birth weight or preterm

UK Teratology Information Service2014

39. Cohort study: Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern

Cohort study: Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name (...) or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern Article Text Aetiology Cohort study Ibuprofen does not seem to increase global malformation risk but NSAID use in late pregnancy remains a concern Christine Damase

Evidence-Based Medicine (Requires free registration)2014

40. Effects of non-steroidal anti-inflammatory drugs (NSAIDs) on bone fracture healing

Effects of non-steroidal anti-inflammatory drugs (NSAIDs) on bone fracture healing Effects of non-steroidal anti-inflammatory drugs (NSAIDs) on bone fracture healing Effects of non-steroidal anti-inflammatory drugs (NSAIDs) on bone fracture healing Tsertsvadze A, Leas B, Umscheid CA Record Status This is a bibliographic record of a published health technology assessment. No evaluation of the quality of this assessment has been made for the HTA database. Citation Tsertsvadze A, Leas B, Umscheid (...) CA. Effects of non-steroidal anti-inflammatory drugs (NSAIDs) on bone fracture healing. Philadelphia: Center for Evidence-based Practice (CEP). 2013 Final publication URL Indexing Status Subject indexing assigned by CRD MeSH Anti-Inflammatory Agents, Non-Steroidal; Fracture Healing; Fractures, Bones Language Published English Country of organisation United States English summary An English language summary is available. Address for correspondence Center for Evidence-based Practice, University

Health Technology Assessment (HTA) Database.2013