Latest & greatest articles for nsaids

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Top results for nsaids

1. Acute gout: Oral steroids work as well as NSAIDs

Acute gout: Oral steroids work as well as NSAIDs Acute gout: Oral steroids work as well as NSAIDs Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Acute gout: Oral steroids work as well as NSAIDs View/ Open Date 2008-10 Format Metadata Abstract Use a short course of oral steroids (prednisone 30-40mg/d for 5 days (...) ) for treatment of acute gout when nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated. Steroids are also a reasonable choice as first-line treatment. Strength of recommendation: B: 2 good-quality, randomized controlled trials (RCTs). URI Part of Citation Journal of Family Practice, 57(10) 2008: 655-657. Collections hosted by hosted by

2019 PURLS

2. Omega-3 PUFA vs. NSAIDs for Preventing Cardiac Inflammation (PubMed)

Omega-3 PUFA vs. NSAIDs for Preventing Cardiac Inflammation 30406113 2018 11 14 2297-055X 5 2018 Frontiers in cardiovascular medicine Front Cardiovasc Med Omega-3 PUFA vs. NSAIDs for Preventing Cardiac Inflammation. 146 10.3389/fcvm.2018.00146 Ye Jiayu J Irving K. Barber School of Arts and Sciences (IKBSAS), Department of Biology, University of University of British Columbia, Kelowna, BC, Canada. Ghosh Sanjoy S Irving K. Barber School of Arts and Sciences (IKBSAS), Department of Biology (...) , University of University of British Columbia, Kelowna, BC, Canada. eng Journal Article 2018 10 23 Switzerland Front Cardiovasc Med 101653388 2297-055X EPA NSAIDs aspirin docosahexaenoic acid (DHA) inflammation 2018 04 26 2018 10 01 2018 11 9 6 0 2018 11 9 6 0 2018 11 9 6 1 epublish 30406113 10.3389/fcvm.2018.00146 PMC6205954 J Am Coll Nutr. 2002 Dec;21(6):495-505 12480795 J Nutr. 2002 Dec;132(12):3566-76 12468590 N Engl J Med. 1991 Jul 11;325(2):87-91 2052056 J Assoc Physicians India. 2002 Aug;50:1028-33

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2018 Frontiers in cardiovascular medicine

3. NSAIDs

NSAIDs Top results for nsaids - Trip Database or use your Google+ account Liberating the literature My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search (...) button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for nsaids The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory

2018 Trip Latest and Greatest

4. NSAIDs: Are They All the Same?

NSAIDs: Are They All the Same? NSAIDs: Are They All the Same? | Clinical Correlations NSAIDs: Are They All the Same? February 1, 2018 By Vishal Shah, MD Peer Reviewed Nonsteroidal antiinflammatory drugs (NSAIDs) are a heterogenous group of non-opioid analgesics and anti-inflammatory agents. Their use is ubiquitous, from treating a simple tension headache to a sprained ankle. NSAIDs are available over the counter and in prescription form. NSAID use in the United States is rising; . 1 (...) nature of these agents, . 3 NSAIDs inhibit cyclooxygenase (COX), an enzyme involved in the production of prostaglandins. Although COX-1 is present in most tissues, it plays a crucial role in gastric cytoprotection and platelet aggregation. COX-2 is primarily involved in the inflammatory response, with additional role in vasoprotection and regulation of renal blood flow. Based on their COX-2 selectivity, NSAIDs can be grouped into 3 categories: Non-selective (ibuprofen, naproxen), COX-2 selective

2018 Clinical Correlations

5. Vonoprazan prevents ulcer recurrence during long-term NSAID therapy: randomised, lansoprazole-controlled non-inferiority and single-blind extension study

Vonoprazan prevents ulcer recurrence during long-term NSAID therapy: randomised, lansoprazole-controlled non-inferiority and single-blind extension study 28988197 2017 10 08 2017 10 08 1468-3288 2017 Oct 07 Gut Gut Vonoprazan prevents ulcer recurrence during long-term NSAID therapy: randomised, lansoprazole-controlled non-inferiority and single-blind extension study. gutjnl-2017-314010 10.1136/gutjnl-2017-314010 To assess the non-inferiority of vonoprazan to lansoprazole for secondary (...) prevention of non-steroidal anti-inflammatory drug (NSAID)-induced peptic ulcer (PU) and the safety of vonoprazan during extended use. A phase 3, 24-week, multicenter, randomised, double-blind (DB), active-controlled study, followed by a phase 3, ≥28 week, multicenter, single-blind, parallel-group extension study (EXT) in outpatients (n=642) receiving long-term NSAID therapy who are at risk of PU recurrence. The patients received vonoprazan (10 mg or 20 mg) or lansoprazole 15 mg once daily. For DB, non

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2017 EvidenceUpdates

6. In patients with localized acute soft tissue or musculoskeletal pain, does topical lidocaine provide better temporary pain relief than topical NSAIDs?

In patients with localized acute soft tissue or musculoskeletal pain, does topical lidocaine provide better temporary pain relief than topical NSAIDs? In patients with localized acute soft tissue or musculoskeletal pain, does topical lidocaine provide better temporary pain relief than topical NSAIDs? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace (...) This Collection Browse Statistics In patients with localized acute soft tissue or musculoskeletal pain, does topical lidocaine provide better temporary pain relief than topical NSAIDs? View/ Open Date 2017-06 Format Metadata Abstract In patients with localized acute soft tissue or musculoskeletal pain, does topical lidocaine provide better temporary pain relief than topical NSAIDs? Evidence-based answer: The answer is unknown, but both topical agents appear effective. Topical NSAIDs provide a 50% reduction

2017 Evidence Based Practice

7. Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. (PubMed)

Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. BACKGROUND: Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization guidelines for pharmacological treatments for children's persisting pain acknowledge that pain in children is a major public health concern of high significance in most parts of the world. While in the past pain was largely (...) associated pain) is a major health concern. Chronic pain (that is pain lasting three months or longer) can arise in the paediatric population in a variety of pathophysiological classifications (nociceptive, neuropathic, or idiopathic) from genetic conditions, nerve damage pain, chronic musculoskeletal pain, and chronic abdominal pain, as well as for other unknown reasons.Non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat pain, reduce fever, and for their anti-inflammation properties

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2017 Cochrane

8. Non-steroidal anti-inflammatory drugs (NSAIDs) for cancer-related pain in children and adolescents. (PubMed)

Non-steroidal anti-inflammatory drugs (NSAIDs) for cancer-related pain in children and adolescents. BACKGROUND: Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization (WHO) guidelines for pharmacological treatments for persisting pain in children acknowledge that pain in children is a major public health concern of high significance in most parts of the world. Views on children's pain have changed (...) treatments, or mucositis. However, this review focused on pain caused directly by the tumour itself such as nerve infiltration, external nerve compression, and other inflammatory events.Non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat pain, reduce fever, and for their anti-inflammatory properties. They are commonly used within paediatric pain management. NSAIDs are currently licensed for use in western countries, however not approved for infants aged under three months. Primary adverse

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2017 Cochrane

9. Should PPIs be routinely co-prescribed with long-term NSAIDs?

Should PPIs be routinely co-prescribed with long-term NSAIDs? Should PPIs be routinely co-prescribed with long-term NSAIDs? – Morsels of Evidence \t\t\t\r\n\t\t\t \t\t\t\r\n\t\t\t Like this: Like Loading... ","author":{"@type":"Person","name":"Michael Tam"},"image":["https:\/\/evidencebasedmedicine.com.au\/wp-content\/uploads\/2017\/07\/mo2017-7-ee-cover.png"]} Toggle search form Toggle navigation Evidence-based medicine for general practitioners Jul 03 2017 Should PPIs be routinely co (...) -prescribed with long-term NSAIDs? By in , , Journal reference: Rostom A, Dube C, Wells G, et al. Prevention of NSAID-induced gastroduodenal ulcers. Cochrane database of systematic reviews 2002(4):CD002296. Link: Published: June 2011 Evidence cookie says… Proton-pump inhibitors (PPIs) protect against the development of ulcers seen on endoscopy, in patients taking longer-term NSAIDs little data exists on clinical outcomes prophylaxis should be considered for patients at increased risk of gastrointestinal

2017 Morsels of Evidence

10. Should PPIs be routinely co-prescribed with long-term NSAIDs?

Should PPIs be routinely co-prescribed with long-term NSAIDs? Should PPIs be routinely co-prescribed with long-term NSAIDs? – Morsels of Evidence Search Evidence based medicine for general practitioners « Jul 03 Should PPIs be routinely co-prescribed with long-term NSAIDs? Categories: , , by Journal reference: Rostom A, Dube C, Wells G, et al. Prevention of NSAID-induced gastroduodenal ulcers. Cochrane database of systematic reviews 2002(4):CD002296. Link: Published: June 2011 Evidence cookie (...) says… Proton-pump inhibitors (PPIs) protect against the development of ulcers seen on endoscopy, in patients taking longer-term NSAIDs little data exists on clinical outcomes prophylaxis should be considered for patients at increased risk of gastrointestinal toxicity Clinical scenario Josef, a 68-year-old retiree saw me recently with knee osteoarthritis, and he commenced a therapeutic trial of naproxen. Afterwards, a discussion on the GPs Down Under online group made me wonder whether I should have

2017 Morsels of Evidence

11. NSAIDs for Chronic Low Back Pain. (PubMed)

NSAIDs for Chronic Low Back Pain. Clinical Question: Are nonsteroidal anti-inflammatory drugs (NSAIDs) associated with greater pain relief than placebo, other drugs, and nondrug treatments for patients with chronic low back pain? Bottom Line: Compared with placebo, NSAIDs are associated with a small but significant improvement in pain and disability in patients with chronic low back pain, although this difference became nonsignificant when studies with high risk for bias were excluded

2017 JAMA

12. NSAIDs as treatment for uncomplicated urinary tract infections

NSAIDs as treatment for uncomplicated urinary tract infections NSAIDs as treatment for uncomplicated urinary tract infections – Morsels of Evidence \t\t\t\r\n\t\t\t \t\t\t\r\n\t\t\t Like this: Like Loading... ","author":{"@type":"Person","name":"Michael Tam"},"image":["https:\/\/evidencebasedmedicine.com.au\/wp-content\/uploads\/2017\/06\/mo2017-5.png"]} Toggle search form Toggle navigation Evidence-based medicine for general practitioners Jun 09 2017 NSAIDs as treatment for uncomplicated (...) urinary tract infections By in , , Journal reference: Gagyor I, Bleidorn J, Kochen MM, Schmiemann G, Wegscheider K, Hummers-Pradier E. Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial. Bmj 2015 Dec 23;351:h6544. Link: Published: December 2015 Evidence cookie says… NSAIDs should not be recommended as a first line treatment for uncomplicated UTIs in women compared with women who received empirical antibiotics, those who received regular

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2017 Morsels of Evidence

13. NSAIDs as treatment for uncomplicated urinary tract infections

NSAIDs as treatment for uncomplicated urinary tract infections NSAIDs as treatment for uncomplicated urinary tract infections » Morsels of Evidence Search Evidence based medicine for general practitioners « Jun 09 NSAIDs as treatment for uncomplicated urinary tract infections Categories: , , by Journal reference: Gagyor I, Bleidorn J, Kochen MM, Schmiemann G, Wegscheider K, Hummers-Pradier E. Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled (...) trial. Bmj 2015 Dec 23;351:h6544. Link: Published: December 2015 Evidence cookie says… NSAIDs should not be recommended as a first line treatment for uncomplicated UTIs in women compared with empirical antibiotics, women who received regular ibuprofen experienced more UTI symptoms most women who received NSAIDs did recovery from the UTI Clinical scenario Evangeline, a 21-year-old female university student, recently presented with typical symptoms of uncomplicated cystitis. I recalled a discussion

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2017 Morsels of Evidence

14. Unborn children still exposed to NSAIDs

Unborn children still exposed to NSAIDs Prescrire IN ENGLISH - Spotlight ''In the April issue of Prescrire International: unborn children still exposed to NSAIDs'', 1 April 2017 {1} {1} {1} | | > > > In the April issue of Prescrire International: unborn children still exposed to NSAIDs Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight In the April (...) issue of Prescrire International: unborn children still exposed to NSAIDs FREE DOWNLOAD In the Adverse Effects section of the April edition: results of a French study showing that around 5% of unborn children in France are exposed to prescribed NSAIDs, including about 1% from the 6th month of pregnancy. And these numbers exclude self-medication. Authorities need to send out a stronger message: "NEVER USE NSAIDs DURING PREGNANCY". Full text available for free download. Summary A study based on data

2017 Prescrire

15. NSAIDs are Caspase Inhibitors (PubMed)

NSAIDs are Caspase Inhibitors 28238723 2017 11 21 2018 11 13 2451-9448 24 3 2017 Mar 16 Cell chemical biology Cell Chem Biol Non-steroidal Anti-inflammatory Drugs Are Caspase Inhibitors. 281-292 S2451-9456(17)30033-8 10.1016/j.chembiol.2017.02.003 Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used drugs in the world. While the role of NSAIDs as cyclooxygenase (COX) inhibitors is well established, other targets may contribute to anti-inflammation. Here we report (...) caspases as a new pharmacological target for NSAID family drugs such as ibuprofen, naproxen, and ketorolac at physiologic concentrations both in vitro and in vivo. We characterize caspase activity in both in vitro and in cell culture, and combine computational modeling and biophysical analysis to determine the mechanism of action. We observe that inhibition of caspase catalysis reduces cell death and the generation of pro-inflammatory cytokines. Further, NSAID inhibition of caspases is COX independent

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2017 Cell chemical biology

16. Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness

Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness | CADTH.ca Find the information you need Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness Published on: January 30, 2017 Project Number: RC0844 (...) -000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the comparative clinical effectiveness of topical NSAIDs versus opioids for the treatment of acute musculoskeletal pain? Key Message Compared with placebo, topical NSAIDs were effective in reducing pain from acute musculoskeletal conditions, such as sprains, strains or sport injuries. Adverse events were rare and were usually related to skin reactions. No evidence regarding

2017 Canadian Agency for Drugs and Technologies in Health - Rapid Review

19. Nonsteroidal anti-inflammatory drug (NSAID) toxicity - emergency management

Nonsteroidal anti-inflammatory drug (NSAID) toxicity - emergency management

2017 DynaMed Plus