Latest & greatest articles for nsaids

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on nsaids or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on nsaids and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for nsaids

1. Acute gout: Oral steroids work as well as NSAIDs

Acute gout: Oral steroids work as well as NSAIDs Acute gout: Oral steroids work as well as NSAIDs Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace This Collection Browse Statistics Acute gout: Oral steroids work as well as NSAIDs View/ Open Date 2008-10 Format Metadata Abstract Use a short course of oral steroids (prednisone 30-40mg/d for 5 days (...) ) for treatment of acute gout when nonsteroidal anti-inflammatory drugs (NSAIDs) are contraindicated. Steroids are also a reasonable choice as first-line treatment. Strength of recommendation: B: 2 good-quality, randomized controlled trials (RCTs). URI Part of Citation Journal of Family Practice, 57(10) 2008: 655-657. Collections hosted by hosted by

PURLS2018

2. NSAIDs

NSAIDs Top results for nsaids - Trip Database or use your Google+ account Liberating the literature My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search (...) button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for nsaids The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory

Trip Latest and Greatest2018

3. NSAIDs: Are They All the Same?

NSAIDs: Are They All the Same? NSAIDs: Are They All the Same? | Clinical Correlations NSAIDs: Are They All the Same? February 1, 2018 By Vishal Shah, MD Peer Reviewed Nonsteroidal antiinflammatory drugs (NSAIDs) are a heterogenous group of non-opioid analgesics and anti-inflammatory agents. Their use is ubiquitous, from treating a simple tension headache to a sprained ankle. NSAIDs are available over the counter and in prescription form. NSAID use in the United States is rising; . 1 (...) nature of these agents, . 3 NSAIDs inhibit cyclooxygenase (COX), an enzyme involved in the production of prostaglandins. Although COX-1 is present in most tissues, it plays a crucial role in gastric cytoprotection and platelet aggregation. COX-2 is primarily involved in the inflammatory response, with additional role in vasoprotection and regulation of renal blood flow. Based on their COX-2 selectivity, NSAIDs can be grouped into 3 categories: Non-selective (ibuprofen, naproxen), COX-2 selective

Clinical Correlations2018

4. Vonoprazan prevents ulcer recurrence during long-term NSAID therapy: randomised, lansoprazole-controlled non-inferiority and single-blind extension study

Vonoprazan prevents ulcer recurrence during long-term NSAID therapy: randomised, lansoprazole-controlled non-inferiority and single-blind extension study 28988197 2017 10 08 2017 10 08 1468-3288 2017 Oct 07 Gut Gut Vonoprazan prevents ulcer recurrence during long-term NSAID therapy: randomised, lansoprazole-controlled non-inferiority and single-blind extension study. gutjnl-2017-314010 10.1136/gutjnl-2017-314010 To assess the non-inferiority of vonoprazan to lansoprazole for secondary (...) prevention of non-steroidal anti-inflammatory drug (NSAID)-induced peptic ulcer (PU) and the safety of vonoprazan during extended use. A phase 3, 24-week, multicenter, randomised, double-blind (DB), active-controlled study, followed by a phase 3, ≥28 week, multicenter, single-blind, parallel-group extension study (EXT) in outpatients (n=642) receiving long-term NSAID therapy who are at risk of PU recurrence. The patients received vonoprazan (10 mg or 20 mg) or lansoprazole 15 mg once daily. For DB, non

EvidenceUpdates2017

5. In patients with localized acute soft tissue or musculoskeletal pain, does topical lidocaine provide better temporary pain relief than topical NSAIDs?

In patients with localized acute soft tissue or musculoskeletal pain, does topical lidocaine provide better temporary pain relief than topical NSAIDs? In patients with localized acute soft tissue or musculoskeletal pain, does topical lidocaine provide better temporary pain relief than topical NSAIDs? Toggle navigation Shared more. Cited more. Safe forever. Toggle navigation View Item JavaScript is disabled for your browser. Some features of this site may not work without it. Search MOspace (...) This Collection Browse Statistics In patients with localized acute soft tissue or musculoskeletal pain, does topical lidocaine provide better temporary pain relief than topical NSAIDs? View/ Open Date 2017-06 Format Metadata Abstract In patients with localized acute soft tissue or musculoskeletal pain, does topical lidocaine provide better temporary pain relief than topical NSAIDs? Evidence-based answer: The answer is unknown, but both topical agents appear effective. Topical NSAIDs provide a 50% reduction

Evidence Based Practice 2017

6. Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents.

Non-steroidal anti-inflammatory drugs (NSAIDs) for chronic non-cancer pain in children and adolescents. BACKGROUND: Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization guidelines for pharmacological treatments for children's persisting pain acknowledge that pain in children is a major public health concern of high significance in most parts of the world. While in the past pain was largely (...) associated pain) is a major health concern. Chronic pain (that is pain lasting three months or longer) can arise in the paediatric population in a variety of pathophysiological classifications (nociceptive, neuropathic, or idiopathic) from genetic conditions, nerve damage pain, chronic musculoskeletal pain, and chronic abdominal pain, as well as for other unknown reasons.Non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat pain, reduce fever, and for their anti-inflammation properties

Cochrane2017

7. Non-steroidal anti-inflammatory drugs (NSAIDs) for cancer-related pain in children and adolescents.

Non-steroidal anti-inflammatory drugs (NSAIDs) for cancer-related pain in children and adolescents. BACKGROUND: Pain is a common feature of childhood and adolescence around the world, and for many young people, that pain is chronic. The World Health Organization (WHO) guidelines for pharmacological treatments for persisting pain in children acknowledge that pain in children is a major public health concern of high significance in most parts of the world. Views on children's pain have changed (...) treatments, or mucositis. However, this review focused on pain caused directly by the tumour itself such as nerve infiltration, external nerve compression, and other inflammatory events.Non-steroidal anti-inflammatory drugs (NSAIDs) are used to treat pain, reduce fever, and for their anti-inflammatory properties. They are commonly used within paediatric pain management. NSAIDs are currently licensed for use in western countries, however not approved for infants aged under three months. Primary adverse

Cochrane2017

8. Should PPIs be routinely co-prescribed with long-term NSAIDs?

Should PPIs be routinely co-prescribed with long-term NSAIDs? Should PPIs be routinely co-prescribed with long-term NSAIDs? – Morsels of Evidence \t\t\t\r\n\t\t\t \t\t\t\r\n\t\t\t Like this: Like Loading... ","author":{"@type":"Person","name":"Michael Tam"},"image":["https:\/\/evidencebasedmedicine.com.au\/wp-content\/uploads\/2017\/07\/mo2017-7-ee-cover.png"]} Toggle search form Toggle navigation Evidence-based medicine for general practitioners Jul 03 2017 Should PPIs be routinely co (...) -prescribed with long-term NSAIDs? By in , , Journal reference: Rostom A, Dube C, Wells G, et al. Prevention of NSAID-induced gastroduodenal ulcers. Cochrane database of systematic reviews 2002(4):CD002296. Link: Published: June 2011 Evidence cookie says… Proton-pump inhibitors (PPIs) protect against the development of ulcers seen on endoscopy, in patients taking longer-term NSAIDs little data exists on clinical outcomes prophylaxis should be considered for patients at increased risk of gastrointestinal

Morsels of Evidence2017

9. Should PPIs be routinely co-prescribed with long-term NSAIDs?

Should PPIs be routinely co-prescribed with long-term NSAIDs? Should PPIs be routinely co-prescribed with long-term NSAIDs? – Morsels of Evidence Search Evidence based medicine for general practitioners « Jul 03 Should PPIs be routinely co-prescribed with long-term NSAIDs? Categories: , , by Journal reference: Rostom A, Dube C, Wells G, et al. Prevention of NSAID-induced gastroduodenal ulcers. Cochrane database of systematic reviews 2002(4):CD002296. Link: Published: June 2011 Evidence cookie (...) says… Proton-pump inhibitors (PPIs) protect against the development of ulcers seen on endoscopy, in patients taking longer-term NSAIDs little data exists on clinical outcomes prophylaxis should be considered for patients at increased risk of gastrointestinal toxicity Clinical scenario Josef, a 68-year-old retiree saw me recently with knee osteoarthritis, and he commenced a therapeutic trial of naproxen. Afterwards, a discussion on the GPs Down Under online group made me wonder whether I should have

Morsels of Evidence2017

10. NSAIDs for Chronic Low Back Pain.

NSAIDs for Chronic Low Back Pain. Clinical Question: Are nonsteroidal anti-inflammatory drugs (NSAIDs) associated with greater pain relief than placebo, other drugs, and nondrug treatments for patients with chronic low back pain? Bottom Line: Compared with placebo, NSAIDs are associated with a small but significant improvement in pain and disability in patients with chronic low back pain, although this difference became nonsignificant when studies with high risk for bias were excluded

JAMA2017

11. NSAIDs as treatment for uncomplicated urinary tract infections

NSAIDs as treatment for uncomplicated urinary tract infections NSAIDs as treatment for uncomplicated urinary tract infections » Morsels of Evidence Search Evidence based medicine for general practitioners « Jun 09 NSAIDs as treatment for uncomplicated urinary tract infections Categories: , , by Journal reference: Gagyor I, Bleidorn J, Kochen MM, Schmiemann G, Wegscheider K, Hummers-Pradier E. Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled (...) trial. Bmj 2015 Dec 23;351:h6544. Link: Published: December 2015 Evidence cookie says… NSAIDs should not be recommended as a first line treatment for uncomplicated UTIs in women compared with empirical antibiotics, women who received regular ibuprofen experienced more UTI symptoms most women who received NSAIDs did recovery from the UTI Clinical scenario Evangeline, a 21-year-old female university student, recently presented with typical symptoms of uncomplicated cystitis. I recalled a discussion

Morsels of Evidence2017

12. NSAIDs as treatment for uncomplicated urinary tract infections

NSAIDs as treatment for uncomplicated urinary tract infections NSAIDs as treatment for uncomplicated urinary tract infections – Morsels of Evidence \t\t\t\r\n\t\t\t \t\t\t\r\n\t\t\t Like this: Like Loading... ","author":{"@type":"Person","name":"Michael Tam"},"image":["https:\/\/evidencebasedmedicine.com.au\/wp-content\/uploads\/2017\/06\/mo2017-5.png"]} Toggle search form Toggle navigation Evidence-based medicine for general practitioners Jun 09 2017 NSAIDs as treatment for uncomplicated (...) urinary tract infections By in , , Journal reference: Gagyor I, Bleidorn J, Kochen MM, Schmiemann G, Wegscheider K, Hummers-Pradier E. Ibuprofen versus fosfomycin for uncomplicated urinary tract infection in women: randomised controlled trial. Bmj 2015 Dec 23;351:h6544. Link: Published: December 2015 Evidence cookie says… NSAIDs should not be recommended as a first line treatment for uncomplicated UTIs in women compared with women who received empirical antibiotics, those who received regular

Morsels of Evidence2017

13. Unborn children still exposed to NSAIDs

Unborn children still exposed to NSAIDs Prescrire IN ENGLISH - Spotlight ''In the April issue of Prescrire International: unborn children still exposed to NSAIDs'', 1 April 2017 {1} {1} {1} | | > > > In the April issue of Prescrire International: unborn children still exposed to NSAIDs Spotlight Every month, the subjects in Prescrire’s Spotlight. 100 most recent :  |   |   |   |   |   |   |   |   |  Spotlight In the April (...) issue of Prescrire International: unborn children still exposed to NSAIDs FREE DOWNLOAD In the Adverse Effects section of the April edition: results of a French study showing that around 5% of unborn children in France are exposed to prescribed NSAIDs, including about 1% from the 6th month of pregnancy. And these numbers exclude self-medication. Authorities need to send out a stronger message: "NEVER USE NSAIDs DURING PREGNANCY". Full text available for free download. Summary A study based on data

Prescrire2017

14. Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness

Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness | CADTH.ca Find the information you need Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness Topical NSAIDs versus Opioids for Acute Musculoskeletal Pain: A Review of the Clinical Effectiveness Published on: January 30, 2017 Project Number: RC0844 (...) -000 Product Line: Research Type: Drug Report Type: Summary with Critical Appraisal Result type: Report Question What is the comparative clinical effectiveness of topical NSAIDs versus opioids for the treatment of acute musculoskeletal pain? Key Message Compared with placebo, topical NSAIDs were effective in reducing pain from acute musculoskeletal conditions, such as sprains, strains or sport injuries. Adverse events were rare and were usually related to skin reactions. No evidence regarding

Canadian Agency for Drugs and Technologies in Health - Rapid Review2017

17. Nonsteroidal anti-inflammatory drug (NSAID) toxicity - emergency management

Nonsteroidal anti-inflammatory drug (NSAID) toxicity - emergency management

DynaMed Plus2017

19. Safety considerations for NSAIDs

Safety considerations for NSAIDs Vol 24. DTB: Vol 24, No 2 - navarra.es Castellano | Euskara | Français | English Use the search tool! Search engine : : : : : : : : DTB: Vol 24, No 2 DTB: Vol 24, No 2 Content tools Share it Safety considerations for NSAIDs The gastrointestinal, cardiovascular, and renal adverse effects of NSAIDs are related to the total daily dose and may appear less than 15 days from the start of treatment. The safest NSAIDs are ibuprofen and naproxen, whether used alone (...) . Although gastrointestinal risk can be countered using gastric protectors, there is no concomitant drug therapy for cardiovascular risk. The results of this review reveal an overuse of celecoxib and etoricoxib in Navarre. NSAIDs in combination with proton pump inhibitors (PPIs) should be used with caution, since PPIs are not indicated for all patients requiring NSAIDs. Furthermore, the combination of these drugs may result in incorrect dosages. Authors: Isabel Aranguren. Pharmacist. Navarre Health

Drug and Therapeutics Bulletin of Navarre (Spain)2016

20. Can topical NSAIDs help relieve the pain of arthritis?

Can topical NSAIDs help relieve the pain of arthritis? Can topical NSAIDs help relieve the pain of arthritis? - Evidently Cochrane Search and hit Go By May 6, 2016 // A blog for non-medical readers by Lynda Ware, Senior Fellow in General Practice with Cochrane UK. “Just put some cream on it….” According to my three daughters, this was my stock response to any request they made for motherly intervention when pain struck. Whilst refuting this slur utterly (and the one about not even looking), I (...) might now point them in the direction of this updated review, which assesses the efficacy and safety of topical nonsteroidal anti-inflammatory drugs (NSAIDs), albeit in the context of chronic musculoskeletal pain rather than a bruised shin or finger. What’s more, I will point out that it’s likely that the carrier, to which the active drug is added, is pretty effective in its own right. Why is this important? Topical NSAIDs can act precisely where needed and without having to be absorbed via

Evidently Cochrane2016