Latest & greatest articles for myocardial infarction

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on myocardial infarction or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on myocardial infarction and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for myocardial infarction

61. PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock.

PCI Strategies in Patients with Acute Myocardial Infarction and Cardiogenic Shock. Background In patients who have acute myocardial infarction with cardiogenic shock, early revascularization of the culprit artery by means of percutaneous coronary intervention (PCI) improves outcomes. However, the majority of patients with cardiogenic shock have multivessel disease, and whether PCI should be performed immediately for stenoses in nonculprit arteries is controversial. Methods In this multicenter (...) trial, we randomly assigned 706 patients who had multivessel disease, acute myocardial infarction, and cardiogenic shock to one of two initial revascularization strategies: either PCI of the culprit lesion only, with the option of staged revascularization of nonculprit lesions, or immediate multivessel PCI. The primary end point was a composite of death or severe renal failure leading to renal-replacement therapy within 30 days after randomization. Safety end points included bleeding and stroke

NEJM2017

62. Effect of Chewing vs Swallowing Ticagrelor on Platelet Inhibition in Patients With ST-Segment Elevation Myocardial Infarction: A Randomized Clinical Trial

Effect of Chewing vs Swallowing Ticagrelor on Platelet Inhibition in Patients With ST-Segment Elevation Myocardial Infarction: A Randomized Clinical Trial 29071332 2018 11 13 2380-6591 2 12 2017 Dec 01 JAMA cardiology JAMA Cardiol Effect of Chewing vs Swallowing Ticagrelor on Platelet Inhibition in Patients With ST-Segment Elevation Myocardial Infarction: A Randomized Clinical Trial. 1380-1384 10.1001/jamacardio.2017.3868 Dual anti-platelet therapy represents standard care for treating patients (...) with ST-segment elevation myocardial infarction (STEMI). Ticagrelor is a direct-acting P2Y12 inhibitor and, unlike clopidogrel and prasugrel, does not require metabolic activation. To evaluate whether chewing a loading dose (LD) of ticagrelor, 180 mg, vs traditional oral administration of an equal dose enhances platelet inhibition at 30 minutes and 1 hour after LD administration in patients with STEMI. A randomized clinical trial was conducted in adults aged 30 to 87 years from May to October 2016

JAMA cardiology2017 Full Text: Link to full Text with Trip Pro

63. Supplemental Oxygen in Acute Myocardial Infarction

Supplemental Oxygen in Acute Myocardial Infarction User Log In Toggle navigation Username: Password: Remember Login Intranet Locations Contact Us Follow Us: F: (314) 362-0478 EM Statistics Adult ED Visits: 95,600 Pediatric ED Visits: 50,000 Trauma Center: Level 1 Residency Type: 1-4 Fellowship Programs: 5 FT Faculty: 40 Residents: 48 | | | | © 2017 by Washington University in St. Louis One Brookings Drive, St. Louis, MO 63130

Washington University Emergency Medicine Journal Club2017

64. Comparison of Outcomes of ST-Elevation Myocardial Infarction Treated by Percutaneous Coronary Intervention During Off-Hours Versus On-Hours

Comparison of Outcomes of ST-Elevation Myocardial Infarction Treated by Percutaneous Coronary Intervention During Off-Hours Versus On-Hours 28893379 2017 09 12 2017 09 12 1879-1913 2017 Aug 04 The American journal of cardiology Am. J. Cardiol. Comparison of Outcomes of ST-Elevation Myocardial Infarction Treated by Percutaneous Coronary Intervention During Off-Hours Versus On-Hours. S0002-9149(17)31288-2 10.1016/j.amjcard.2017.07.082 Previous studies have reported worse outcomes and longer door (...) -to-balloon times (DBTs) in patients presenting with ST-elevation myocardial infarction (STEMI) after normal working hours, during weekends, and on holidays (off-hours) compared with normal business hours (on-hours). Recent studies, however, have reported similar outcomes regardless of presentation time. MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials were queried from January 1990 through December 2016. Only studies comparing STEMI outcomes during off-hours versus on-hours

EvidenceUpdates2017

65. Age Differences in Hospital Mortality for Acute Myocardial Infarction: Implications for Hospital Profiling.

Age Differences in Hospital Mortality for Acute Myocardial Infarction: Implications for Hospital Profiling. Background: Publicly reported hospital risk-standardized mortality rates (RSMRs) for acute myocardial infarction (AMI) are calculated for Medicare beneficiaries. Outcomes for older patients with AMI may not reflect general outcomes. Objective: To examine the relationship between hospital 30-day RSMRs for older patients (aged ≥65 years) and those for younger patients (aged 18 to 64 years (...) ) and all patients (aged ≥18 years) with AMI. Design: Retrospective cohort study. Setting: 986 hospitals in the ACTION (Acute Coronary Treatment and Intervention Outcomes Network) Registry-Get With the Guidelines. Participants: Adults hospitalized for AMI from 1 October 2010 to 30 September 2014. Measurements: Hospital 30-day RSMRs were calculated for older, younger, and all patients using an electronic health record measure of AMI mortality endorsed by the National Quality Forum. Hospitals were ranked

Annals of Internal Medicine2017

66. Sex differences in survival after myocardial infarction in Sweden, 1987-2010

Sex differences in survival after myocardial infarction in Sweden, 1987-2010 28784665 2017 08 08 2017 08 08 1468-201X 2017 Aug 07 Heart (British Cardiac Society) Heart Sex differences in survival after myocardial infarction in Sweden, 1987-2010. heartjnl-2016-310281 10.1136/heartjnl-2016-310281 In this nationwide study, we investigated age-specific and sex-specific trends in sex differences in survival after acute myocardial infarction (AMI), including deaths from coronary heart disease (CHD (...) 15.3% to 7.7% (p<0.05) for both men and women. After adjustment for comorbidities, no significant sex differences persisted below the age of 75 years in the last period. Female 28-day survivors 75-84 years old had a consistently better prognosis than older men. The worse short-term outcomes in women <55 years of age hospitalised with AMI did not persist after adjustment for comorbidities. When CHD deaths outside hospital were included, women had consistently better short-term prognosis. In 28-day

EvidenceUpdates2017 Full Text: Link to full Text with Trip Pro

67. Efficacy and Safety of a Pharmaco-Invasive Strategy With Half-Dose Alteplase Versus Primary Angioplasty in ST-Segment-Elevation Myocardial Infarction: EARLY-MYO Trial (Early Routine Catheterization After Alteplase Fibrinolysis Versus Primary PCI in Acute

Efficacy and Safety of a Pharmaco-Invasive Strategy With Half-Dose Alteplase Versus Primary Angioplasty in ST-Segment-Elevation Myocardial Infarction: EARLY-MYO Trial (Early Routine Catheterization After Alteplase Fibrinolysis Versus Primary PCI in Acute 28844990 2017 08 28 2017 08 28 1524-4539 2017 Aug 27 Circulation Circulation Efficacy and Safety of a Pharmaco-Invasive Strategy With Half-Dose Alteplase Versus Primary Angioplasty in ST-Segment-Elevation Myocardial Infarction: EARLY-MYO Trial (...) (Early Routine Catheterization After Alteplase Fibrinolysis Versus Primary PCI in Acute ST-Segment-Elevation Myocardial Infarction). CIRCULATIONAHA.117.030582 10.1161/CIRCULATIONAHA.117.030582 Background -Timely primary percutaneous coronary intervention (PPCI) cannot be offered to all patients with ST-segment-elevation myocardial infarction (STEMI). Pharmaco-invasive (PhI) strategy has been proposed as a valuable alternative for eligible patients with STEMI. We conducted a randomized study

EvidenceUpdates2017

68. Migraines and Myocardial Infarction in Women

Migraines and Myocardial Infarction in Women "Migraines and Myocardial Infarction in Women" by Haley Moak > > > > Title Author Date of Graduation Summer 8-12-2017 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies Rights . Abstract Background: Heart disease is the number 1 cause of death for U.S. women, myocardial infarction (MI) included. It has been established that ischemic stroke has a positive correlation with those who experience migraines (...) , but there were no definitive studies saying that migraines cause all other cardiovascular related diseases, even though there is a common consensus that migraines are a vascular phenomenon. This systematic review focuses on the correlation between migraines and myocardial infarction particularly in women. Methods: An exhaustive search of available medical literature was conducted using MEDLINE-Ovid, Web of Science, and CINAHL databases. The following terms were searched as keywords: migraine

Pacific University EBM Capstone Project2017

69. Management of Acute Myocardial Infarction in patients presenting with ST-segment elevation

Management of Acute Myocardial Infarction in patients presenting with ST-segment elevation 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation | European Heart Journal | Oxford Academic We use cookies to enhance your experience on our website. By continuing to use our website, you are agreeing to our use of cookies. You can change your cookie settings at any time. Search Account Menu Menu Navbar Search Filter Mobile Microsite (...) Search Term search filter search input Article Navigation Close mobile search navigation Article navigation Article Contents Article Navigation 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC) Authors/Task Force Members: Search for other works by this author on: Borja Ibanez

European Society of Cardiology2017

70. Oxygen Therapy in Suspected Acute Myocardial Infarction.

Oxygen Therapy in Suspected Acute Myocardial Infarction. Background The clinical effect of routine oxygen therapy in patients with suspected acute myocardial infarction who do not have hypoxemia at baseline is uncertain. Methods In this registry-based randomized clinical trial, we used nationwide Swedish registries for patient enrollment and data collection. Patients with suspected myocardial infarction and an oxygen saturation of 90% or higher were randomly assigned to receive either (...) of the highest troponin level during hospitalization was 946.5 ng per liter in the oxygen group and 983.0 ng per liter in the ambient-air group. The primary end point of death from any cause within 1 year after randomization occurred in 5.0% of patients (166 of 3311) assigned to oxygen and in 5.1% of patients (168 of 3318) assigned to ambient air (hazard ratio, 0.97; 95% confidence interval [CI], 0.79 to 1.21; P=0.80). Rehospitalization with myocardial infarction within 1 year occurred in 126 patients (3.8

NEJM2017

71. Bivalirudin versus Heparin Monotherapy in Myocardial Infarction.

Bivalirudin versus Heparin Monotherapy in Myocardial Infarction. Background The comparative efficacy of various anticoagulation strategies has not been clearly established in patients with acute myocardial infarction who are undergoing percutaneous coronary intervention (PCI) according to current practice, which includes the use of radial-artery access for PCI and administration of potent P2Y12 inhibitors without the planned use of glycoprotein IIb/IIIa inhibitors. Methods In this multicenter (...) , randomized, registry-based, open-label clinical trial, we enrolled patients with either ST-segment elevation myocardial infarction (STEMI) or non-STEMI (NSTEMI) who were undergoing PCI and receiving treatment with a potent P2Y12 inhibitor (ticagrelor, prasugrel, or cangrelor) without the planned use of glycoprotein IIb/IIIa inhibitors. The patients were randomly assigned to receive bivalirudin or heparin during PCI, which was performed predominantly with the use of radial-artery access. The primary end

NEJM2017

72. Long-term Safety and Efficacy of New-Generation Drug-Eluting Stents in Women With Acute Myocardial Infarction: From the Women in Innovation and Drug-Eluting Stents (WIN-DES) Collaboration

Long-term Safety and Efficacy of New-Generation Drug-Eluting Stents in Women With Acute Myocardial Infarction: From the Women in Innovation and Drug-Eluting Stents (WIN-DES) Collaboration 28658478 2018 11 13 2380-6591 2 8 2017 Aug 01 JAMA cardiology JAMA Cardiol Long-term Safety and Efficacy of New-Generation Drug-Eluting Stents in Women With Acute Myocardial Infarction: From the Women in Innovation and Drug-Eluting Stents (WIN-DES) Collaboration. 855-862 10.1001/jamacardio.2017.1978 Women (...) with acute myocardial infarction (MI) undergoing mechanical reperfusion remain at increased risk of adverse cardiac events and mortality compared with their male counterparts. Whether the benefits of new-generation drug-eluting stents (DES) are preserved in women with acute MI remains unclear. To investigate the long-term safety and efficacy of new-generation DES vs early-generation DES in women with acute MI. Collaborative, international, individual patient-level data of women enrolled in 26

JAMA cardiology2017 Full Text: Link to full Text with Trip Pro

73. Cost-Effectiveness of Long-Term Ticagrelor in Patients With Prior Myocardial Infarction: Results From the PEGASUS-TIMI 54 Trial

Cost-Effectiveness of Long-Term Ticagrelor in Patients With Prior Myocardial Infarction: Results From the PEGASUS-TIMI 54 Trial 28750695 2017 07 28 2017 07 28 1558-3597 70 5 2017 Aug 01 Journal of the American College of Cardiology J. Am. Coll. Cardiol. Cost-Effectiveness of Long-Term Ticagrelor in Patients With Prior Myocardial Infarction: Results From the PEGASUS-TIMI 54 Trial. 527-538 S0735-1097(17)37692-1 10.1016/j.jacc.2017.05.063 In patients with a myocardial infarction (MI) 1 to 3 years (...) earlier, treatment with ticagrelor + low-dose aspirin (ASA) reduces the risk of cardiovascular (CV) death, MI, or stroke compared with low-dose aspirin alone, but at an increased risk of major bleeding. The authors evaluated cost-effectiveness of ticagrelor + low-dose ASA in patients with prior MI within the prior 3 years. The authors performed a prospective economic substudy alongside the PEGASUS-TIMI 54 (Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor

EvidenceUpdates2017

74. Ventricular Arrhythmia after Acute Myocardial Infarction: ‘The Perfect Storm’

Ventricular Arrhythmia after Acute Myocardial Infarction: ‘The Perfect Storm’ 29018522 2018 11 13 2050-3369 6 3 2017 Aug Arrhythmia & electrophysiology review Arrhythm Electrophysiol Rev Ventricular Arrhythmia after Acute Myocardial Infarction: 'The Perfect Storm'. 134-139 10.15420/aer.2017.24.1 Ventricular tachyarrhythmias (VAs) commonly occur early in ischaemia, and remain a common cause of sudden death in acute MI. The thrombolysis and primary percutaneous coronary intervention era has (...) resulted in the modification of the natural history of an infarct and subsequent VA. Presence of VA could independently influence mortality in patients recovering from MI. Appropriate risk assessment and subsequent treatment is warranted in these patients. The prevention and treatment of haemodynamically significant VA in the post-infarct period and of sudden cardiac death remote from the event remain areas of ongoing study. Bhar-Amato Justine J Papworth Hospital NHS Foundation Trust, Papworth Everard

Arrhythmia & electrophysiology review2017 Full Text: Link to full Text with Trip Pro

75. Circulating Prolidase Activity in Patients with Myocardial Infarction

Circulating Prolidase Activity in Patients with Myocardial Infarction 28824924 2018 11 13 2297-055X 4 2017 Frontiers in cardiovascular medicine Front Cardiovasc Med Circulating Prolidase Activity in Patients with Myocardial Infarction. 50 10.3389/fcvm.2017.00050 Collagen is a major determinant of atherosclerotic plaque stability. Thus, identification of differences in enzymes that regulate collagen integrity could be useful for predicting susceptibility to atherothrombosis or for diagnosing (...) plaque rupture. In this study, we sought to determine whether prolidase, the rate-limiting enzyme of collagen turnover, differs in human subjects with acute myocardial infarction (MI) versus those with stable coronary artery disease (CAD). We measured serum prolidase activity in 15 patients with stable CAD and 49 patients with acute MI, of which a subset had clearly defined thrombotic MI ( n = 22) or non-thrombotic MI ( n = 12). Prolidase activity was compared across study time points (at cardiac

Frontiers in cardiovascular medicine2017 Full Text: Link to full Text with Trip Pro

76. Association of Genetic Variants Related to Serum Calcium Levels With Coronary Artery Disease and Myocardial Infarction.

Association of Genetic Variants Related to Serum Calcium Levels With Coronary Artery Disease and Myocardial Infarction. Importance: Serum calcium has been associated with cardiovascular disease in observational studies and evidence from randomized clinical trials indicates that calcium supplementation, which raises serum calcium levels, may increase the risk of cardiovascular events, particularly myocardial infarction. Objective: To evaluate the potential causal association between genetic (...) variants related to elevated serum calcium levels and risk of coronary artery disease (CAD) and myocardial infarction using mendelian randomization. Design, Setting, and Participants: The analyses were performed using summary statistics obtained for single-nucleotide polymorphisms (SNPs) identified from a genome-wide association meta-analysis of serum calcium levels (N = up to 61 079 individuals) and from the Coronary Artery Disease Genome-wide Replication and Meta-analysis Plus the Coronary

JAMA2017 Full Text: Link to full Text with Trip Pro

77. Exploring the adaptive experiences of children with parents of myocardial infarction: A Qualitative Study

Exploring the adaptive experiences of children with parents of myocardial infarction: A Qualitative Study 28894554 2018 11 13 2008-5842 9 7 2017 Jul Electronic physician Electron Physician Exploring the adaptive experiences of children with parents of myocardial infarction: A Qualitative Study. 4906-4913 10.19082/4906 Cardiovascular diseases are the world's leading cause of mortality. These diseases are rooted in an unhealthy lifestyle. In order to confront this subject, it is essential (...) to identify several risk factors that contribute to heart disease (HD) in people with different attitudes, values, beliefs, expectations and motivations. This study was therefore an attempt to explain the adaptive experiences of children whose parents were involved in myocardial infarction since they were more likely subjected to get the so-called disease. To identify the risk factors and to clear ambiguity using a qualitative research method from the experiences of people at risk of the above mentioned

Electronic physician2017 Full Text: Link to full Text with Trip Pro

78. Vitamin D Uptake in Patients Treated with a High-Dosed Purified Omega-3 Compound in a Randomized Clinical Trial Following an Acute Myocardial Infarction

Vitamin D Uptake in Patients Treated with a High-Dosed Purified Omega-3 Compound in a Randomized Clinical Trial Following an Acute Myocardial Infarction 28791297 2018 11 13 2297-055X 4 2017 Frontiers in cardiovascular medicine Front Cardiovasc Med Vitamin D Uptake in Patients Treated with a High-Dosed Purified Omega-3 Compound in a Randomized Clinical Trial Following an Acute Myocardial Infarction. 41 10.3389/fcvm.2017.00041 Fish is the natural dietary source of vitamin D. Reports (...) on the influence of purified omega-3 fatty acids on its uptake are scarce. We investigated the impact of a purified high-dose omega-3 compound compared to corn oil on 25-hydroxyvitamin D [25(OH)D] levels following an acute myocardial infarction. 228 patients were randomized 1:1 to receive a daily dose of either 4 g omega-3 (OMACOR ® ) or an equal dose of corn oil, administered double-blindly for 12 months. Total omega-3 and omega-6 measurements were available in 40 randomly picked patients

Frontiers in cardiovascular medicine2017 Full Text: Link to full Text with Trip Pro

79. Accuracy of Medical Claims for Identifying Cardiovascular and Bleeding Events After Myocardial Infarction : A Secondary Analysis of the TRANSLATE-ACS Study

Accuracy of Medical Claims for Identifying Cardiovascular and Bleeding Events After Myocardial Infarction : A Secondary Analysis of the TRANSLATE-ACS Study 28538984 2018 11 13 2380-6591 2 7 2017 Jul 01 JAMA cardiology JAMA Cardiol Accuracy of Medical Claims for Identifying Cardiovascular and Bleeding Events After Myocardial Infarction : A Secondary Analysis of the TRANSLATE-ACS Study. 750-757 10.1001/jamacardio.2017.1460 Pragmatic clinical trial designs have proposed the use of medical claims (...) year of the index acute myocardial infarction (MI) of 12 365 patients enrolled in the Treatment With Adenosine Diphosphate Receptor Inhibitors: Longitudinal Assessment of Treatment Patterns and Events After Acute Coronary Syndrome (TRANSLATE-ACS) study between April 1, 2010, and October 31, 2012. Fourteen patients (0.1%) died during the index hospitalization and were excluded from analysis. Recurrent MI, stroke, and bleeding events were identified per the International Classification of Diseases

JAMA cardiology2017 Full Text: Link to full Text with Trip Pro

80. Use of Prescription Smoking Cessation Medications After Myocardial Infarction Among Older Patients in Community Practice

Use of Prescription Smoking Cessation Medications After Myocardial Infarction Among Older Patients in Community Practice 28724116 2018 11 13 2380-6591 2 9 2017 Sep 01 JAMA cardiology JAMA Cardiol Use of Prescription Smoking Cessation Medications After Myocardial Infarction Among Older Patients in Community Practice. 1040-1042 10.1001/jamacardio.2017.2369 Pagidipati Neha J NJ Duke Clinical Research Institute, Duke University, Durham, North Carolina. Hellkamp Anne A Duke Clinical Research

JAMA cardiology2017 Full Text: Link to full Text with Trip Pro