Latest & greatest articles for myocardial infarction

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Top results for myocardial infarction

181. Concern for Myocardial Infarction Risk Associated with Proton Pump Inhibitor Use in Patients With No Underlying Cardiovascular Disease

Concern for Myocardial Infarction Risk Associated with Proton Pump Inhibitor Use in Patients With No Underlying Cardiovascular Disease "Concern for Myocardial Infarction Risk Associated with Proton Pump Inh" by Natasha K. Ludwig < > > > > > Title Author Date of Award Fall 8-13-2016 Degree Type Capstone Project Degree Name Master of Science in Physician Assistant Studies First Advisor Saje Davis-Risen, PA-C, MS Second Advisor Annjanette Sommers, PA-C, MS Rights . Abstract Background (...) : Proton pump inhibitors (PPIs) are the drugs of choice when it comes to the treatment of dyspepsia and gastroesophageal reflux disease (GERD). Recently, the FDA issued a warning regarding concomitant use of omeprazole, a PPI, with clopidogrel as it interferes with CYP2C19 activity. The pharmacological activity of clopidogrel is decreased, possibly increasing the potential for an acute cardiac event. However, there is limited evidence with regards to myocardial infarct (MI) risk with use of PPIs alone. The purpose

Pacific University EBM Capstone Project2016

182. Randomised controlled trial: Supplemental oxygen in patients without hypoxia in ST segment elevation myocardial infarction increases myocardial injury and infarct size

Randomised controlled trial: Supplemental oxygen in patients without hypoxia in ST segment elevation myocardial infarction increases myocardial injury and infarct size Supplemental oxygen in patients without hypoxia in ST segment elevation myocardial infarction increases myocardial injury and infarct size | Evidence-Based Medicine This site uses cookies. By continuing to browse the site you are agreeing to our use of cookies. Log in using your username and password For personal accounts (...) OR managers of institutional accounts Username * Password * your user name or password? Search for this keyword Search for this keyword Main menu Log in using your username and password For personal accounts OR managers of institutional accounts Username * Password * your user name or password? You are here Supplemental oxygen in patients without hypoxia in ST segment elevation myocardial infarction increases myocardial injury and infarct size Article Text Therapeutics/Prevention Randomised controlled

Evidence-Based Medicine (Requires free registration)2016

183. Acute Myocardial Infarction in Women

Acute Myocardial Infarction in Women Acute Myocardial Infarction in Women | Circulation Search for this keyword Search Search for this keyword Search Header Publisher Menu AHA Scientific Statement Acute Myocardial Infarction in Women A Scientific Statement From the American Heart Association Laxmi S. Mehta , Theresa M. Beckie , Holli A. DeVon , Cindy L. Grines , Harlan M. Krumholz , Michelle N. Johnson , Kathryn J. Lindley , Viola Vaccarino , Tracy Y. Wang , Karol E. Watson , Nanette K. Wenger (...) on women and cardiovascular disease risk, and the increased application of evidence-based treatments for established coronary heart disease. This is the first scientific statement from the American Heart Association on acute myocardial infarction in women. Sex-specific differences exist in the presentation, pathophysiological mechanisms, and outcomes in patients with acute myocardial infarction. This statement provides a comprehensive review of the current evidence of the clinical presentation

American Heart Association2016 Full Text: Link to full Text with Trip Pro

184. Ischaemic risk and efficacy of ticagrelor in relation to time from P2Y12 inhibitor withdrawal in patients with prior myocardial infarction: insights from PEGASUS-TIMI 54

Ischaemic risk and efficacy of ticagrelor in relation to time from P2Y12 inhibitor withdrawal in patients with prior myocardial infarction: insights from PEGASUS-TIMI 54 26491109 2016 04 08 2017 01 17 2017 01 17 1522-9645 37 14 2016 Apr 07 European heart journal Eur. Heart J. Ischaemic risk and efficacy of ticagrelor in relation to time from P2Y12 inhibitor withdrawal in patients with prior myocardial infarction: insights from PEGASUS-TIMI 54. 1133-42 10.1093/eurheartj/ehv531 Ticagrelor reduced (...) major adverse cardiovascular event (MACE) by 15-16% in patients with prior myocardial infarction (MI) in PEGASUS-TIMI 54. We hypothesized that patients who recently discontinued P2Y12 inhibition, even years after MI, may be at particular risk of MACE and may derive particular benefit from continuation or reinitiation of therapy. Patients in PEGASUS-TIMI 54 were categorized by time from last P2Y12 inhibitor (days: ≤30, >30-360, >360). The risk of MACE and the efficacy of ticagrelor were compared

EvidenceUpdates2015 Full Text: Link to full Text with Trip Pro

185. Cardioprotection by combined intrahospital remote ischaemic perconditioning and postconditioning in ST-elevation myocardial infarction: the randomized LIPSIA CONDITIONING trial

Cardioprotection by combined intrahospital remote ischaemic perconditioning and postconditioning in ST-elevation myocardial infarction: the randomized LIPSIA CONDITIONING trial 26385956 2015 11 22 2016 09 13 2015 11 22 1522-9645 36 44 2015 Nov 21 European heart journal Eur. Heart J. Cardioprotection by combined intrahospital remote ischaemic perconditioning and postconditioning in ST-elevation myocardial infarction: the randomized LIPSIA CONDITIONING trial. 3049-57 10.1093/eurheartj/ehv463 (...) Remote ischaemic conditioning (RIC) and postconditioning (PostC) are both potent activators of innate protection against ischaemia-reperfusion injury and have demonstrated cardioprotection in experimental and clinical ST-elevation myocardial infarction (STEMI) trials. However, their combined effects have not been studied in detail. The aim of this study was to evaluate if the co-application of intrahospital RIC and PostC has a more powerful effect on myocardial salvage compared with either PostC

EvidenceUpdates2015 Full Text: Link to full Text with Trip Pro

186. Development and Validation of a Distal Embolization Risk Score During Primary Angioplasty in ST-Elevation Myocardial Infarction

Development and Validation of a Distal Embolization Risk Score During Primary Angioplasty in ST-Elevation Myocardial Infarction 26260396 2015 09 29 2015 12 29 2016 11 25 1879-1913 116 8 2015 Oct 15 The American journal of cardiology Am. J. Cardiol. Development and Validation of a Distal Embolization Risk Score During Primary Angioplasty in ST-Elevation Myocardial Infarction. 1172-8 10.1016/j.amjcard.2015.07.027 S0002-9149(15)01687-2 This study aims to develop and validate a new angiographic (...) risk score to predict the risk of distal embolization (DE) during primary percutaneous coronary intervention (p-PCI) for ST-elevation myocardial infarction. Study included data from 1,200 patients who underwent p-PCI. The cohort was randomly split into a derivation cohort (n = 814) and a validation cohort (n = 386). Logistic regression was used to examine the relation between risk factors and the occurrence of DE. To each covariate in the model was assigned an integer score based on the regression

EvidenceUpdates2015

187. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction.

Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 26398078 (...) Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2015 Sep 24;373(13):1274-5. doi: 10.1056/NEJMc1508692. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. , , . Comment on [N Engl J Med. 2015] [N Engl J Med. 2015] [N Engl J Med. 2015] [N Engl J Med. 2015] [N Engl J Med. 2015] [N Engl J Med. 2015] PMID: 26398078

NEJM2015 Full Text: Link to full Text with Trip Pro

188. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction.

Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 26398079 (...) Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2015 Sep 24;373(13):1271. doi: 10.1056/NEJMc1508692#SA1. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. , , . Comment in [N Engl J Med. 2015] Comment on [N Engl J Med. 2015] PMID: 26398079 DOI: [Indexed for MEDLINE] Publication types MeSH terms Substances

NEJM2015 Full Text: Link to full Text with Trip Pro

189. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction.

Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 26398080 (...) Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2015 Sep 24;373(13):1271-2. doi: 10.1056/NEJMc1508692#SA2. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. , . Comment in [N Engl J Med. 2015] Comment on [N Engl J Med. 2015] PMID: 26398080 DOI: [Indexed for MEDLINE] Publication types MeSH terms Substances

NEJM2015 Full Text: Link to full Text with Trip Pro

190. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction.

Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 26398081 (...) Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2015 Sep 24;373(13):1272-3. doi: 10.1056/NEJMc1508692#SA3. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. . Comment in [N Engl J Med. 2015] Comment on [N Engl J Med. 2015] PMID: 26398081 DOI: [Indexed for MEDLINE] Publication types MeSH terms Substances Full

NEJM2015 Full Text: Link to full Text with Trip Pro

191. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction.

Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 26398082 (...) Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2015 Sep 24;373(13):1273-4. doi: 10.1056/NEJMc1508692#SA4. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. , , . Comment in [N Engl J Med. 2015] Comment on [N Engl J Med. 2015] PMID: 26398082 DOI: [Indexed for MEDLINE] Publication types MeSH terms Substances

NEJM2015 Full Text: Link to full Text with Trip Pro

192. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction.

Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 26398083 (...) Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2015 Sep 24;373(13):1274. doi: 10.1056/NEJMc1508692#SA5. Long-Term Use of Ticagrelor in Patients with Prior Myocardial Infarction. , , . Comment in [N Engl J Med. 2015] Comment on [N Engl J Med. 2015] PMID: 26398083 DOI: [Indexed for MEDLINE] Publication types MeSH terms Substances

NEJM2015 Full Text: Link to full Text with Trip Pro

193. Cyclosporine before PCI in Patients with Acute Myocardial Infarction.

Cyclosporine before PCI in Patients with Acute Myocardial Infarction. BACKGROUND: Experimental and clinical evidence suggests that cyclosporine may attenuate reperfusion injury and reduce myocardial infarct size. We aimed to test whether cyclosporine would improve clinical outcomes and prevent adverse left ventricular remodeling. METHODS: In a multicenter, double-blind, randomized trial, we assigned 970 patients with an acute anterior ST-segment elevation myocardial infarction (STEMI) who were (...) to 1.39; P=0.77). Cyclosporine did not reduce the incidence of the separate clinical components of the primary outcome or other events, including recurrent infarction, unstable angina, and stroke. No significant difference in the safety profile was observed between the two treatment groups. CONCLUSIONS: In patients with anterior STEMI who had been referred for primary PCI, intravenous cyclosporine did not result in better clinical outcomes than those with placebo and did not prevent adverse left

NEJM2015 Full Text: Link to full Text with Trip Pro

194. Mesenteric Ischemia Mimicking ST-Segment Elevation Myocardial Infarction.

Mesenteric Ischemia Mimicking ST-Segment Elevation Myocardial Infarction. Mesenteric Ischemia Mimicking ST-Segment Elevation Myocardial Infarction. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography Citation manager Format Create File 1 selected item: 26287866 (...) Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2015 Aug 20;373(8):780-1. doi: 10.1056/NEJMc1506103. Mesenteric Ischemia Mimicking ST-Segment Elevation Myocardial Infarction. 1 , , . 1 Far Eastern Memorial Hospital, New Taipei City, Taiwan chungming_t@yahoo.com.tw. PMID: 26287866 DOI: [Indexed for MEDLINE] Free full text Publication

NEJM2015

195. Complete revascularisation versus treatment of the culprit lesion only in patients with ST-segment elevation myocardial infarction and multivessel disease (DANAMI-3—PRIMULTI): an open-label, randomised controlled trial.

Complete revascularisation versus treatment of the culprit lesion only in patients with ST-segment elevation myocardial infarction and multivessel disease (DANAMI-3—PRIMULTI): an open-label, randomised controlled trial. BACKGROUND: Patients with acute ST-segment elevation myocardial infarction (STEMI) and multivessel coronary disease have a worse prognosis compared with individuals with single-vessel disease. We aimed to study the clinical outcome of patients with STEMI treated with fractional (...) flow reserve (FFR)-guided complete revascularisation versus treatment of the infarct-related artery only. METHODS: We undertook an open-label, randomised controlled trial at two university hospitals in Denmark. Patients presenting with STEMI who had one or more clinically significant coronary stenosis in addition to the lesion in the infarct-related artery were included. After successful percutaneous coronary intervention (PCI) of the infarct-related artery, patients were randomly allocated (in a 1

Lancet2015

196. Comparison of hospital variation in acute myocardial infarction care and outcome between Sweden and United Kingdom: population based cohort study using nationwide clinical registries.

Comparison of hospital variation in acute myocardial infarction care and outcome between Sweden and United Kingdom: population based cohort study using nationwide clinical registries. OBJECTIVE: To assess the between hospital variation in use of guideline recommended treatments and clinical outcomes for acute myocardial infarction in Sweden and the United Kingdom. DESIGN: Population based longitudinal cohort study using nationwide clinical registries. SETTING AND PARTICIPANTS: Nationwide (...) registry data comprising all hospitals providing acute myocardial infarction care in Sweden (SWEDEHEART/RIKS-HIA, n=87; 119,786 patients) and the UK (NICOR/MINAP, n=242; 391,077 patients), 2004-10. MAIN OUTCOME MEASURES: Between hospital variation in 30 day mortality of patients admitted with acute myocardial infarction. RESULTS: Case mix standardised 30 day mortality from acute myocardial infarction was lower in Swedish hospitals (8.4%) than in UK hospitals (9.7%), with less variation between

BMJ2015 Full Text: Link to full Text with Trip Pro

197. Stroke in the TOTAL trial: a randomized trial of routine thrombectomy vs. percutaneous coronary intervention alone in ST elevation myocardial infarction

Stroke in the TOTAL trial: a randomized trial of routine thrombectomy vs. percutaneous coronary intervention alone in ST elevation myocardial infarction 26129947 2015 09 15 2016 06 27 2016 12 15 1522-9645 36 35 2015 Sep 14 European heart journal Eur. Heart J. Stroke in the TOTAL trial: a randomized trial of routine thrombectomy vs. percutaneous coronary intervention alone in ST elevation myocardial infarction. 2364-72 10.1093/eurheartj/ehv296 TOTAL (N = 10 732), a randomized trial of routine (...) manual thrombectomy vs. percutaneous coronary intervention alone in ST elevation myocardial infarction, showed no difference in the primary efficacy outcome but a significant increase in stroke. We sought to understand these findings. A detailed analysis of stroke timing, stroke severity, and stroke subtype was performed. Strokes were adjudicated by neurologists blinded to treatment assignment. Stroke within 30 days, the primary safety outcome, was increased [33 (0.7%) vs. 16 (0.3%), hazard ratio (HR

EvidenceUpdates2015 Full Text: Link to full Text with Trip Pro

198. Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction

Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction 26002889 2015 06 16 2015 08 26 2016 11 25 1524-4539 131 24 2015 Jun 16 Circulation Circulation Air Versus Oxygen in ST-Segment-Elevation Myocardial Infarction. 2143-50 10.1161/CIRCULATIONAHA.114.014494 Oxygen is commonly administered to patients with ST-elevation-myocardial infarction despite previous studies suggesting a possible increase in myocardial injury as a result of coronary vasoconstriction and heightened oxidative stress (...) . We conducted a multicenter, prospective, randomized, controlled trial comparing oxygen (8 L/min) with no supplemental oxygen in patients with ST-elevation-myocardial infarction diagnosed on paramedic 12-lead ECG. Of 638 patients randomized, 441 patients had confirmed ST-elevation-myocardial infarction and underwent primary end-point analysis. The primary end point was myocardial infarct size as assessed by cardiac enzymes, troponin I, and creatine kinase. Secondary end points included recurrent

EvidenceUpdates2015

199. High-sensitivity troponin assays for the early rule-out or diagnosis of acute myocardial infarction in people with acute chest pain: a systematic review and cost-effectiveness analysis

High-sensitivity troponin assays for the early rule-out or diagnosis of acute myocardial infarction in people with acute chest pain: a systematic review and cost-effectiveness analysis High-sensitivity troponin assays for the early rule-out or diagnosis of acute myocardial infarction in people with acute chest pain: a systematic review and cost-effectiveness analysis Journals Library An error occurred retrieving content to display, please try again. >> >> >> Page Not Found Page not found (404 (...) ) Sorry - the page you requested could not be found. Please choose a page from the navigation or try a website search above to find the information you need. >> >> >> >> Issue {{metadata .Issue }} Toolkit 1)"> 0)"> {{metadata.Title}} {{metadata.Headline}} The study found some evidence to suggest that high-sensitivity cardiac troponin testing may provide an effective and cost-effective approach to the early rule-out of acute myocardial infarction in adults presenting with acute chest pain. {{author

NIHR HTA programme2015

200. Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Acute Myocardial Infarction.

Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Acute Myocardial Infarction. IMPORTANCE: Implantable cardioverter-defibrillators (ICDs) are not recommended within 40 days of myocardial infarction (MI); thus, ICD implantation might not be considered during the post-MI care transition. OBJECTIVE: To examine ICD implantation rates and associated mortality among older MI patients with low ejection fraction (EF). DESIGN, SETTING, AND PARTICIPANTS (...) : Retrospective observational study of Medicare beneficiaries with an EF of 35% or less after MI, treated at 441 US hospitals between 2007 and 2010, excluding patients with prior ICD implantation. Follow-up data were available through December 2010. EXPOSURES: ICD implantation within 1 year of MI vs no ICD implantation within 1 year of MI. MAIN OUTCOMES AND MEASURES: Patient characteristics associated with receiving an ICD within 1 year after discharge and 2-year mortality associated with ICD implantation

JAMA2015 Full Text: Link to full Text with Trip Pro