Latest & greatest articles for menopause

The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on menopause or other clinical topics then use Trip today.

This page lists the very latest high quality evidence on menopause and also the most popular articles. Popularity measured by the number of times the articles have been clicked on by fellow users in the last twelve months.

What is Trip?

Trip is a clinical search engine designed to allow users to quickly and easily find and use high-quality research evidence to support their practice and/or care.

Trip has been online since 1997 and in that time has developed into the internet’s premier source of evidence-based content. Our motto is ‘Find evidence fast’ and this is something we aim to deliver for every single search.

As well as research evidence we also allow clinicians to search across other content types including images, videos, patient information leaflets, educational courses and news.

For further information on Trip click on any of the questions/sections on the left-hand side of this page. But if you still have questions please contact us via jon.brassey@tripdatabase.com

Top results for menopause

1. Menopause

Menopause Menopause - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Menopause Last reviewed: February 2019 Last updated: February 2019 Summary The diagnosis is clinical, based on the absence of menses for 12 months, and does not require further testing for appropriately presenting patients. Oestrogen therapy is an effective treatment for the management of menopausal symptoms including hot flushes, night sweats (...) , and is unlikely to increase the risk of stroke or venous thrombosis above that of non-users. Non-hormonal interventions may help women who have a contraindication to, or cannot tolerate, HT. However, they are less effective than HT in controlling menopausal symptoms. Definition Onset of the menopause is heralded by the cessation of menses for at least 12 consecutive months, without some other reason for amenorrhoea (such as pregnancy, hormone therapy, or other medical condition). No further testing

2019 BMJ Best Practice

2. Treatments for reducing menopausal hot flushes are ranked for effectiveness

Treatments for reducing menopausal hot flushes are ranked for effectiveness Treatments for reducing menopausal hot flushes are ranked for effectiveness Discover Portal Discover Portal Treatments for reducing menopausal hot flushes are ranked for effectiveness Published on 25 July 2017 doi: A combination of oestrogen and progestogen via patches is the best treatment for menopause symptoms. Other options may be less beneficial, including tablets combining oestrogen and progestogen, and non (...) -hormonal treatments, isoflavones and black cohosh, though they may have other benefits. There is no evidence to support the use of antidepressants. Menopause affects women’s personal life and work life, but many don’t seek help from healthcare professionals. It is important to identify the most effective and safest treatment to help women in this transitional period. This review compared treatment options for the short-term management of hot flushes and night sweats in women aged 45 years or older who

2019 NIHR Dissemination Centre

3. Effects of acute dietary nitrate supplementation on aortic blood pressures and pulse wave characteristics in post-menopausal women. (PubMed)

Effects of acute dietary nitrate supplementation on aortic blood pressures and pulse wave characteristics in post-menopausal women. Consumption of nitrate-rich beetroot juice can lower blood pressure in peripheral as well as central arteries and may exert additional hemodynamic benefits (e.g. reduced aortic wave reflections). The specific influence of nitrate supplementation on arterial pressures and aortic wave properties in postmenopausal women, a group that experiences accelerated increases (...) ± 1 yr) before and 100 min after consumption of 140 ml of either nitrate-rich (9.7 mmol, 0.6 gm NO3-) or nitrate-depleted beetroot juice on randomized visits approximately 10 days apart (cross-over design). Ten young premenopausal women (22 ± 1 yr) served as a reference (non-supplemented) cohort.Brachial and derived-aortic variables showed the expected age-associated differences in these women (all p < 0.05). In post-menopausal women, nitrate supplementation reduced (p < 0.05 vs. placebo visit

2019 Nitric oxide : biology and chemistry

4. Fracture risk reduction by anti-osteoporosis pharmacotherapy according to baseline fracture risk among post-menopausal women (protocol for a systematic review and meta-analysis of randomised trials)

Fracture risk reduction by anti-osteoporosis pharmacotherapy according to baseline fracture risk among post-menopausal women (protocol for a systematic review and meta-analysis of randomised trials) Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears

2019 PROSPERO

5. A systematic review assessing the efficacy of treatments for genitourinary symptoms of menopause in women with breast cancer

A systematic review assessing the efficacy of treatments for genitourinary symptoms of menopause in women with breast cancer Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears no responsibility or liability for the content of this registration record, any

2019 PROSPERO

6. Mindfulness-based stress reduction for menopausal symptoms after risk-reducing salpingo-oophorectomy (PURSUE study): a randomised controlled trial

Mindfulness-based stress reduction for menopausal symptoms after risk-reducing salpingo-oophorectomy (PURSUE study): a randomised controlled trial To assess the short- and long-term effects of mindfulness-based stress reduction (MBSR) on the resulting quality of life, sexual functioning, and sexual distress after risk-reducing salpingo-oophorectomy (RRSO).Randomised controlled trial.A specialised family cancer clinic of the university medical center Groningen.Sixty-six women carriers (...) of the BRCA1/2 mutation who developed at least two moderate-to-severe menopausal symptoms after RRSO.Women were randomised to an 8-week MBSR training programme or to care as usual (CAU).Change in the Menopause-Specific Quality of Life Questionnaire (MENQOL), the Female Sexual Function Index, and the Female Sexual Distress Scale, administered from baseline at 3, 6, and 12 months. Linear mixed modelling was applied to compare the effect of MBSR with CAU over time.At 3 and 12 months, there were statistically

2018 EvidenceUpdates

7. Acupuncture for symptoms in menopause transition: a randomized controlled trial

Acupuncture for symptoms in menopause transition: a randomized controlled trial Acupuncture has been used for women during menopause transition, but evidence is limited.We sought to evaluate the efficacy of electroacupuncture on relieving symptoms of women during menopause transition.We conducted a prospective, multicenter, randomized, participant-blinded trial in China mainland. Subjects were randomized to receive 24 treatment sessions of electroacupuncture at traditional acupoints or sham (...) electroacupuncture at nonacupoints over 8 weeks with 24 weeks' follow-up. Primary outcome was the change from baseline in the total score of Menopause Rating Scale at week 8. Secondary outcomes included the changes from baseline in the average 24-hour hot flash score, the Menopause Rating Scale subscale scores, the total score of Menopause-Specific Quality of Life Questionnaire and its subscales, and serum female hormones. All analyses were performed with a 2-sided P value of < .05 considered significant based

2018 EvidenceUpdates

8. Menopause

Menopause Top results for menopause - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 (...) or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for menopause The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence

2018 Trip Latest and Greatest

9. Menopause

Menopause Evidence Maps - Trip Database or use your Google+ account Turning Research Into Practice ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing the search button. An example search might look like (#1 or #2) and (#3 or #4

2018 Trip Evidence Maps

10. Mindfulness, cognitive behavioural and behaviour-based therapy for natural and treatment-induced menopausal symptoms: a systematic review and meta-analysis

Mindfulness, cognitive behavioural and behaviour-based therapy for natural and treatment-induced menopausal symptoms: a systematic review and meta-analysis During menopause women experience vasomotor and psychosexual symptoms that cannot entirely be alleviated with hormone replacement therapy (HRT). Besides, HRT is contraindicated after breast cancer.To review the evidence on the effectiveness of psychological interventions in reducing symptoms associated with menopause in natural or treatment (...) -induced menopausal women.Medline/Pubmed, PsycINFO, EMBASE and AMED were searched until June 2017.Randomised controlled trials (RCTs) concerning natural or treatment-induced menopause, investigating mindfulness or (cognitive-)behaviour-based therapy were selected. Main outcomes were frequency of hot flushes, hot flush bother experienced, other menopausal symptoms and sexual functioning.Study selection and data extraction were performed by two independent researchers. A meta-analysis was performed

Full Text available with Trip Pro

2018 EvidenceUpdates

11. Treatments for reducing menopausal hot flushes are ranked for effectiveness

Treatments for reducing menopausal hot flushes are ranked for effectiveness Treatments for reducing menopausal hot flushes are ranked for effectiveness Discover Portal Discover Portal Treatments for reducing menopausal hot flushes are ranked for effectiveness Published on 25 July 2017 doi: A combination of oestrogen and progestogen via patches is the best treatment for menopause symptoms. Other options may be less beneficial, including tablets combining oestrogen and progestogen, and non (...) -hormonal treatments, isoflavones and black cohosh, though they may have other benefits. There is no evidence to support the use of antidepressants. Menopause affects women’s personal life and work life, but many don’t seek help from healthcare professionals. It is important to identify the most effective and safest treatment to help women in this transitional period. This review compared treatment options for the short-term management of hot flushes and night sweats in women aged 45 years or older who

2018 NIHR Dissemination Centre

12. Longitudinal Effects of Adjuvant Endocrine Therapy on the Quality of Life of Post-menopausal Women with Non-metastatic ER+ Breast Cancer: A Systematic Review.

Longitudinal Effects of Adjuvant Endocrine Therapy on the Quality of Life of Post-menopausal Women with Non-metastatic ER+ Breast Cancer: A Systematic Review. Anti-estrogen (ER) endocrine therapy is an effective treatment strategy in reducing breast cancer mortality. This therapy has a better therapeutic index than chemotherapy but can still affect patients' quality of life (QOL) over time.The objectives of this systematic review were to (1) describe QOL instruments used in ER-positive (ER (...) +) non-metastatic breast cancer trials and (2) document the longitudinal effects of adjuvant endocrine therapy on the QOL of post-menopausal women with ER+ non-metastatic breast cancer.We searched three electronic bibliographic databases for articles published from inception to October 2017 that described (1) a randomized controlled trial (RCT) of non-metastatic breast cancer containing an adjuvant endocrine regimen in at least one arm; (2) the use of a patient self-report measure assessing general

Full Text available with Trip Pro

2018 PharmacoEconomics - open

13. [Gender Features of Radical Oxidation of Lipids in Menopausal Women and Men in Andropause]. (PubMed)

[Gender Features of Radical Oxidation of Lipids in Menopausal Women and Men in Andropause]. Our aim was to assess lipid peroxidation ― antioxidant protection in menopausal women and men in andropause and to compare these processes in different gender and age groups.74 women and 37 men were examined. This study was a prospective, randomized cohort study. Women were divided into perimenopausal group (n=22, mean age 49.03±3.13), postmenopausal group (n=15, mean age 54.43±4.54) and control (n=37 (...) by 43% (p<0,05), α-tocopherol by 24% (p<0.05), SOD activity by 9% (p<0.05).Coefficient oxidative stress in perimenopausal women was 2,5, in postmenopausal ― 3,48, in andropause ― 0,97.Expressed lipid peroxidation activity is more physiological in andropause than in menopause. Men in andropause have large functional reserves and adaptive capacity than menopausal women.

Full Text available with Trip Pro

2018 Vestnik Rossiiskoi akademii meditsinskikh nauk

14. Should This Patient Receive Hormone Therapy for Her Menopausal Symptoms?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. (PubMed)

Should This Patient Receive Hormone Therapy for Her Menopausal Symptoms?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center. Hormone therapy (HT) was widely prescribed in the 1980s and 1990s and has been controversial since the initial results of the Women's Health Initiative (WHI) trial in the early 2000s suggested that it increased risk for breast cancer and coronary heart disease and did not prolong life. However, more recent data and reexamination of the WHI results suggest (...) that HT is safe and effective for many women when used around the time of menopause. Two experts debate the 2017 Hormone Therapy Position Statement of The North American Menopause Society, which recommends HT as first-line treatment of vasomotor symptoms, and apply it to the care of Ms. R, a 52-year-old woman with severe hot flashes, sleep disturbance, and irritability.

2018 Annals of Internal Medicine

15. Menopause

Menopause CLINICAL PROFESSIONAL RESOURCE Menopause RCN guidance for nurses, midwives and health visitors Endorsed by This publication is supported by industryMENOPAUSE 2 This publication is due for review in November 2020. To provide feedback on its contents or on your experience of using the publication, please email publications.feedback@rcn.org.uk Acknowledgements This new publication is based on, and replaces, previous RCN publications – Women’s Health and the Menopause: RCN Guidance (...) for Nurses, Midwives and Health Visitors (RCN, 2005 and 2014) and Complementary Approaches to Menopausal Symptoms: RCN Guidance for Nurses, Midwives and Health Visitors (RCN, 2006). The RCN Women’s Health Forum would like to thank the menopause project team for the development of this publication: Debra Holloway (project chair), Nurse Consultant Gynaecology, Guy’s and St Thomas’ NHS Foundation Trust and Chair of the RCN Women’s Health Forum Carmel Bagness, RCN Professional Lead Midwifery and Women’s

2018 Royal College of Nursing

16. Abnormal Uterine Bleeding in Pre-Menopausal Women

Abnormal Uterine Bleeding in Pre-Menopausal Women No. 292-Abnormal Uterine Bleeding in Pre-Menopausal Women - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 40, Issue 5, Pages e391–e415 No. 292-Abnormal Uterine Bleeding in Pre-Menopausal Women x Sukhbir Singh , MD Ottawa, ON x Carolyn Best , MD Toronto, ON x Sheila Dunn , MD Toronto, ON x Nicholas Leyland , MD Toronto, ON x Wendy Lynn Wolfman , MD Toronto, ON No 292

2018 Society of Obstetricians and Gynaecologists of Canada

17. Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence

Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence No. 358-Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence - Journal of Obstetrics and Gynaecology Canada Email/Username: Password: Remember me Search Terms Search within Search Volume 40, Issue 4, Pages 503–511 No. 358-Intravaginal Laser for Genitourinary Syndrome of Menopause and Stress Urinary Incontinence x Jens-Erik Walter , MD Montréal, QC x Annick Larochelle (...) , MD Montréal, QC No. 358, April 2018 DOI: To view the full text, please login as a subscribed user or . Click to view the full text on ScienceDirect. Figures Figure Comparative pre- and post-laser vaginal biopsies. Abstract Objective This technical bulletin reviews the evidence relating to risks and benefits of using intravaginal laser technology in the management of genitourinary syndrome of menopause and stress urinary incontinence. Intended Users Gynaecologists, urogynaecologists, urologists

2018 Society of Obstetricians and Gynaecologists of Canada

18. Menopause

Menopause Menopause - Symptoms, diagnosis and treatment | BMJ Best Practice You'll need a subscription to access all of BMJ Best Practice Search  Menopause Last reviewed: February 2019 Last updated: February 2019 Summary The diagnosis is clinical, based on the absence of menses for 12 months, and does not require further testing for appropriately presenting patients. Oestrogen therapy is an effective treatment for the management of menopausal symptoms including hot flushes, night sweats (...) , and is unlikely to increase the risk of stroke or venous thrombosis above that of non-users. Non-hormonal interventions may help women who have a contraindication to, or cannot tolerate, HT. However, they are less effective than HT in controlling menopausal symptoms. Definition Onset of the menopause is heralded by the cessation of menses for at least 12 consecutive months, without some other reason for amenorrhoea (such as pregnancy, hormone therapy, or other medical condition). No further testing

2018 BMJ Best Practice

19. A review of effective herbal medicines in controlling menopausal symptoms (PubMed)

A review of effective herbal medicines in controlling menopausal symptoms Acute menopausal syndrome especially hot flashes, is one of the most common gynecological problems during menopause. Due to the side effects of hormone therapy, herbal and complementary medicines are always of immense interest to people in the treatment and management of the symptoms and complications of menopause.The aim of this study was to investigate the mechanisms and effects of medicinal plants employed (...) in the treatment of menopausal symptoms.This review article was carried out by examining clinical trial studies between the period of 1994 and 2016. The keywords, which include menopause, climacteric, hot flushes, flashes, herb and phytoestrogens were used to search for herbal medicines used in clinical trials for the treatment of menopausal symptoms using databases such as PubMed, Medline, Scopus, Google scholar, SID and Magiran.The results of the study showed that the medicinal plants, which include Sage

Full Text available with Trip Pro

2017 Electronic physician

20. Effects of teriparatide and risedronate on new fractures in post-menopausal women with severe osteoporosis (VERO): a multicentre, double-blind, double-dummy, randomised controlled trial. (PubMed)

Effects of teriparatide and risedronate on new fractures in post-menopausal women with severe osteoporosis (VERO): a multicentre, double-blind, double-dummy, randomised controlled trial. No clinical trials have compared osteoporosis drugs with incident fractures as the primary outcome. We compared the anti-fracture efficacy of teriparatide with risedronate in patients with severe osteoporosis.In this double-blind, double-dummy trial, we enrolled post-menopausal women with at least two moderate (...) in the risedronate group (hazard ratio 0·48, 95% CI 0·32-0·74; p=0·0009). Non-vertebral fragility fractures occurred in 25 (4·0%) patients in the teriparatide group and 38 (6·1%) in the risedronate group (hazard ratio 0·66; 95% CI 0·39-1·10; p=0·10).Among post-menopausal women with severe osteoporosis, the risk of new vertebral and clinical fractures is significantly lower in patients receiving teriparatide than in those receiving risedronate.Lilly.Copyright © 2018 Elsevier Ltd. All rights reserved.

2017 Lancet