Latest & greatest articles for memantine

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Top results for memantine

1. Memantine

Memantine Top results for memantine - Trip Database or use your Google+ account Turning Research Into Practice My query is: English Français Deutsch Čeština Español Magyar Svenska ALL of these words: Title only Anywhere in the document ANY of these words: Title only Anywhere in the document This EXACT phrase: Title only Anywhere in the document EXCLUDING words: Title only Anywhere in the document Timeframe: to: Combine searches by placing the search numbers in the top search box and pressing (...) the search button. An example search might look like (#1 or #2) and (#3 or #4) Loading history... Population: Intervention: Comparison: Outcome: Population: Intervention: Latest & greatest articles for memantine The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines

2018 Trip Latest and Greatest

2. Evidence-based Clinical Practice Guideline for Deprescribing Cholinesterase Inhibitors and Memantine

Evidence-based Clinical Practice Guideline for Deprescribing Cholinesterase Inhibitors and Memantine Evidence-based Clinical Practice Guideline for Deprescribing Cholinesterase Inhibitors and Memantine Developing organisations: The University of Sydney NHMRC Partnership Centre: Dealing with Cognitive and Related Functional Decline in Older People (Cognitive Decline Partnership Centre) Bruyère Research Institute, Deprescribing Guidelines in the Elderly Project Evidence-based clinical practice (...) guideline for deprescribing cholinesterase inhibitors and memantine: 2018 2 © The University of Sydney ISBN Online: 978-0-6482658-0-1 ISBN Print: 978-0-6482658-1-8 Publication date: February 2018 Suggested citation: Reeve E, Farrell B, Thompson W, Herrmann N, Sketris I, Magin P, Chenoweth L, Gorman M, Quirke L, Bethune G, Forbes F, Hilmer S. Evidence-based Clinical Practice Guideline for Deprescribing Cholinesterase Inhibitors and Memantine. Sydney: The University of Sydney; 2018. The full guideline

2018 Clinical Practice Guidelines Portal

3. Memantine and Cognition in Parkinson's Disease Dementia/Dementia With Lewy Bodies: A Meta‐Analysis (PubMed)

Memantine and Cognition in Parkinson's Disease Dementia/Dementia With Lewy Bodies: A Meta‐Analysis 30363483 2018 11 14 2330-1619 3 2 2016 Mar-Apr Movement disorders clinical practice Mov Disord Clin Pract Memantine and Cognition in Parkinson's Disease Dementia/Dementia With Lewy Bodies: A Meta-Analysis. 161-167 10.1002/mdc3.12264 The aim of this work was to utilize meta-analysis in examining the effects of memantine on neuropsychological functioning in patients with Parkinson's disease (...) dementia (PDD) and dementia with Lewy bodies (DLB). Included studies fulfilled these criteria: included objective cognitive measures, a comparison group of participants not taking memantine, and provided sufficient data for calculation of effect size. We examined effect sizes across global cognition and five specific neuropsychological domains. Moderator variables examined included neuropsychological domain, diagnostic cohort (PDD, DLB, or mixed PDD-DLB cohort), study design (open label or placebo

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2015 Movement disorders clinical practice

4. EFNS-ENS/EAN Guideline on concomitant use of cholinesteraseinhibitors and memantine in moderate to severe Alzheimer?s disease

EFNS-ENS/EAN Guideline on concomitant use of cholinesteraseinhibitors and memantine in moderate to severe Alzheimer?s disease EFNS‐ENS/EAN Guideline on concomitant use of cholinesterase inhibitors and memantine in moderate to severe Alzheimer's disease - Schmidt - 2015 - European Journal of Neurology - Wiley Online Library The full text of this article hosted at iucr.org is unavailable due to technical difficulties.

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2015 European Academy of Neurology

5. Efficacy of memantine in the treatment of fibromyalgia: A double-blind, randomised, controlled trial with 6-month follow-up (PubMed)

Efficacy of memantine in the treatment of fibromyalgia: A double-blind, randomised, controlled trial with 6-month follow-up 25218600 2014 12 01 2015 07 15 2015 11 19 1872-6623 155 12 2014 Dec Pain Pain Efficacy of memantine in the treatment of fibromyalgia: A double-blind, randomised, controlled trial with 6-month follow-up. 2517-25 10.1016/j.pain.2014.09.004 S0304-3959(14)00424-2 Fibromyalgia (FM) is a prevalent and disabling chronic disease. Recent studies have found elevated levels (...) of glutamate in several brain regions, leading to hypotheses about the usefulness of glutamate-blocking drugs such as memantine in the treatment of FM. The aim of this study was to evaluate the efficacy of memantine in the treatment of pain and other clinical variables (global function, clinical impression, depression, anxiety, quality of life) in FM patients. A double-blind, parallel randomised controlled trial was developed. A total of 63 patients diagnosed with FM were recruited from primary health care

2014 EvidenceUpdates

6. Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial. (PubMed)

Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial. 24381967 2014 01 01 2014 01 13 2017 02 20 1538-3598 311 1 2014 Jan 01 JAMA JAMA Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial. 33-44 10.1001/jama.2013.282834 Although vitamin E and memantine have been shown to have beneficial effects in moderately severe Alzheimer disease (AD), evidence is limited (...) in mild to moderate AD. To determine if vitamin E (alpha tocopherol), memantine, or both slow progression of mild to moderate AD in patients taking an acetylcholinesterase inhibitor. Double-blind, placebo-controlled, parallel-group, randomized clinical trial involving 613 patients with mild to moderate AD initiated in August 2007 and concluded in September 2012 at 14 Veterans Affairs medical centers. Participants received either 2000 IU/d of alpha tocopherol (n = 152), 20 mg/d of memantine (n = 155

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2014 JAMA

7. Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial. (PubMed)

Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial. IMPORTANCE: Although vitamin E and memantine have been shown to have beneficial effects in moderately severe Alzheimer disease (AD), evidence is limited in mild to moderate AD. OBJECTIVE: To determine if vitamin E (alpha tocopherol), memantine, or both slow progression of mild to moderate AD in patients taking an acetylcholinesterase inhibitor. DESIGN, SETTING (...) , AND PARTICIPANTS: Double-blind, placebo-controlled, parallel-group, randomized clinical trial involving 613 patients with mild to moderate AD initiated in August 2007 and concluded in September 2012 at 14 Veterans Affairs medical centers. INTERVENTIONS: Participants received either 2000 IU/d of alpha tocopherol (n = 152), 20 mg/d of memantine (n = 155), the combination (n = 154), or placebo (n = 152). MAIN OUTCOMES AND MEASURES: Alzheimer's Disease Cooperative Study/Activities of Daily Living (ADCS-ADL

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2014 JAMA

8. Namzaric (memantine hydrochloride extended-release/donepezil hydrochloride) Capsules

Namzaric (memantine hydrochloride extended-release/donepezil hydrochloride) Capsules Namzaric (memantine hydrochloride extended-release/donepezil hydrochloride) Capsules U.S. Department of Health and Human Services Search FDA Submit search Namzaric (memantine hydrochloride extended-release/donepezil hydrochloride) Capsules Namzaric (memantine hydrochloride extended-release/donepezil hydrochloride) Capsules Company: Forest Laboratories, Inc. Application No.: 206439 Approval Date: 12/23/2014

2014 FDA - Drug Approval Package

9. Randomised controlled trial: Cessation of donepezil is associated with clinical decline in patients with moderate-to-severe Alzheimer's disease compared to continuation of donepezil or addition or substitution of memantine

Randomised controlled trial: Cessation of donepezil is associated with clinical decline in patients with moderate-to-severe Alzheimer's disease compared to continuation of donepezil or addition or substitution of memantine Cessation of donepezil is associated with clinical decline in patients with moderate-to-severe Alzheimer's disease compared to continuation of donepezil or addition or substitution of memantine | Evidence-Based Medicine This site uses cookies. By continuing to browse the site (...) -to-severe Alzheimer's disease compared to continuation of donepezil or addition or substitution of memantine Article Text Therapeutics Randomised controlled trial Cessation of donepezil is associated with clinical decline in patients with moderate-to-severe Alzheimer's disease compared to continuation of donepezil or addition or substitution of memantine Pierre N Tariot Statistics from Altmetric.com No Altmetric data available for this article. Commentary on: Howard R , McShane R , Lindesay J , et al

2013 Evidence-Based Medicine (Requires free registration)

10. Nemdatine - memantine

Nemdatine - memantine London, 21 February 2013 EMA/228869/2013 Committee for Medicinal Products for Human Use (CHMP) Assessment report Nemdatine International non-proprietary name: Memantine Procedure No. EMEA/H/C/002680 Assessment Report as adopted by the CHMP with all information of a commercially confidential nature deleted 7 Westferry Circus ? Canary Wharf ? London E14 4HB ? United Kingdom An agency of the European Union Telephone +44 (0)20 7418 8400 Facsimile +44 (0)20 7418 8545 E-mail (...) a Marketing Authorisation to Nemdatine. Assessment report EMA/CHMP/87358/2013 Page 6/19 2. Scientific discussion 2.1. Introduction Nemdatine 5 mg, 10 mg, 15 mg and 20 mg film coated tablets is a generic medicinal product of Ebixa, which has been authorised in the EU since 15 May 2002. The active substance of Nemdatine is memantine hydrochloride, a psychoanaleptic, anti-dementia drug (N06DX01). Memantine is a voltage-dependent, moderate-affinity non-competitive N-methyl-D- aspartate (NMDA) receptor

2013 European Medicines Agency - EPARs

11. Memantine LEK

Memantine LEK London, 21 February 2013 EMA/227468/2013 Committee for Medicinal Products for Human Use (CHMP) Assessment report Memantine LEK International non-proprietary name: Memantine Procedure No. EMEA/H/C/002630 Assessment Report as adopted by the CHMP with all information of a commercially confidential nature deleted 7 Westferry Circus ? Canary Wharf ? London E14 4HB ? United Kingdom An agency of the European Union Telephone +44 (0)20 7418 8400 Facsimile +44 (0)20 7418 8545 E-mail info (...) . Pharmacovigilance 17 3. Benefit-risk balance 17 4. Recommendation 18 Memantine LEK EMA/227468/2013 Page 2/18 List of abbreviations AEs adverse events Al or Alu Aluminium ASMF active substance master file AUC0-t Area under the plasma concentration curve from administration to last observed concentration at time t. AUC0- 8 Area under the plasma concentration curve extrapolated to infinite time BE Bioequivalence BMI body mass index Cmax Maximum plasma concentration CLcr creatinine clearance CHMP or CPMP Committee

2013 European Medicines Agency - EPARs

12. Memantine Mylan

Memantine Mylan London, 21 February 2013 EMA/229868/2013 Committee for Medicinal Products for Human Use (CHMP) Assessment report Memantine Mylan International non-proprietary name: Memantine Procedure No. EMEA/H/C/002660 Assessment Report as adopted by the CHMP with all commercially confidential information removed 7 Westferry Circus ? Canary Wharf ? London E14 4HB ? United Kingdom An agency of the European Union Telephone +44 (0)20 7418 8400 Facsimile +44 (0)20 7418 8545 E-mail info (...) . Conclusions on the chemical, pharmaceutical and biological aspects 11 2.3. Non-clinical aspects 11 2.3.1. Introduction 11 2.3.2. Ecotoxicity/environmental risk assessment 12 2.3.3. Discussion on non-clinical aspects 12 2.3.4. Conclusion on the non-clinical aspects 12 2.4. Clinical aspects 12 2.5. Pharmacovigilance 19 3. Benefit-risk balance 20 4. Recommendation 20 Memantine Mylan EMA/CHMP/91208/2013 Page 2/21 List of abbreviations AAS Atomic Absorption Spectrometry AP Applicant’s Part API Active

2013 European Medicines Agency - EPARs

13. Memantine Accord

Memantine Accord 19 September 2013 EMA/610378/2013 Committee for Medicinal Products for Human Use (CHMP) Assessment report Memantine Accord International non-proprietary name: memantine Procedure No. EMEA/H/C/002766 Note Assessment report as adopted by the CHMP with all information of a commercially confidential nature deleted 7 Westferry Circus ? Canary Wharf ? London E14 4HB ? United Kingdom An agency of the European Union Telephone +44 (0)20 7418 8400 Facsimile +44 (0)20 7523 7455 E-mail (...) on the procedure 1.1. Submission of the dossier The applicant Accord Healthcare Limited submitted on 3 September 2012 an application for Marketing Authorisation to the European Medicines Agency (EMA) for Memantine Accord, through the centralised procedure under Article 3 (3) of Regulation (EC) No. 726/2004– ‘Generic of a Centrally authorised product’. The eligibility to the centralised procedure was agreed upon by the EMA/CHMP on 21 June 2012. The application concerns a generic medicinal product as defined

2013 European Medicines Agency - EPARs

14. Acrescent (memantine hydrochloride / donepezil hydrochloride)

Acrescent (memantine hydrochloride / donepezil hydrochloride) 18 October 2012 EMA/111381/2013 Committee for Medicinal Products for Human Use (CHMP) Assessment report Acrescent International non-proprietary name: memantine hydrochloride / donepezil hydrochloride Procedure No. EMEA/H/C/002424 Note Assessment report as adopted by the CHMP with all information of a commercially confidential nature deleted. 7 Westferry Circus ? Canary Wharf ? London E14 4HB ? United Kingdom An agency of the European (...) Assessment report Page 2/63 IMP Investigational medicinal product IMS-IPD IMS-Prescribing Insights Database ip intraperitoneal IT Italy ITT Intent to treat LC/MS/MS Liquid chromatography with tandem mass spectrometric detection LOCF Last observation carried forward Log Kow octanol-water partition coefficient MADRS Montgomery and åsberg depression rating scale MCID Minimal clinically important difference MDS Minimum data set MEM/DPZ Memantine/ donepezil MMSE Mini mental state examination MoA Mechanism

2013 European Medicines Agency - EPARs

15. Balaxur (memantine hydrochloride / donepezil hydrochloride)

Balaxur (memantine hydrochloride / donepezil hydrochloride) 18 October 2012 EMA/817438/2012 Committee for Medicinal Products for Human Use (CHMP) Assessment report Balaxur International non-proprietary name: memantine hydrochloride / donepezil hydrochloride Procedure No. EMEA/H/C/002708 Note Assessment report as adopted by the CHMP with all information of a commercially confidential nature deleted. 7 Westferry Circus ? Canary Wharf ? London E14 4HB ? United Kingdom An agency of the European (...) Assessment report Page 2/63 IMP Investigational medicinal product IMS-IPD IMS-Prescribing Insights Database ip intraperitoneal IT Italy ITT Intent to treat LC/MS/MS Liquid chromatography with tandem mass spectrometric detection LOCF Last observation carried forward Log Kow octanol-water partition coefficient MADRS Montgomery and åsberg depression rating scale MCID Minimal clinically important difference MDS Minimum data set MEM/DPZ Memantine/ donepezil MMSE Mini mental state examination MoA Mechanism

2013 European Medicines Agency - EPARs

16. Marixino (previously Maruxa) - memantine

Marixino (previously Maruxa) - memantine 7 Westferry Circus ? Canary Wharf ? London E14 4HB ? United Kingdom An agency of the European Union Telephone +44 (0)20 7418 8400 Facsimile +44 (0)20 7418 8416 E-mail info@ema.europa.eu Website www.ema.europa.eu © European Medicines Agency, 2013. Reproduction is authorised provided the source is acknowledged. 17 January 2013 EMA/293975/2013 Committee for Medicinal Products for Human Use (CHMP) Assessment report Maruxa International non-proprietary name (...) : Memantine Procedure No. EMEA/H/C/002658 Assessment report as adopted by the CHMP with all commercially confidential information deleted Assessment report EMA/293975/2013 Page 2/20 Product information Marketing authorisation application Name of the medicinal product: Maruxa Applicant: Krka d.d. Novo mesto Šmarješka cesta 6 8501 Novo mesto SLOVENIA Active substance: Memantine hydrochloride International Nonproprietary Name: Memantine Pharmaco-therapeutic group (ATC Code): Other anti-dementia drugs(N06DX01

2013 European Medicines Agency - EPARs

17. Memantine ratiopharm

Memantine ratiopharm 7 Westferry Circus ? Canary Wharf ? London E14 4HB ? United Kingdom An agency of the European Union Telephone +44 (0)20 7418 8400 Facsimile +44 (0)20 7418 8613 E-mail info@ema.europa.eu Website www.ema.europa.eu © European Medicines Agency, 2013. Reproduction is authorised provided the source is acknowledged. 21 March 2013 EMA/328117/2013 Committee for Medicinal Products for Human Use (CHMP) Memantine ratiopharm memantine Procedure No. EMEA/H/C/002671/0000 Assessment report (...) for initial marketing authorisation application Assessment report as adopted by the CHMP with all commercially confidential information deleted Memantine Ratiopharm CHMP assessment report Page 1/19 Table of contents 1. Background information on the procedure 3 1.1. Submission of the dossier 3 1.2. Steps taken for the assessment of the product 4 2. Scientific discussion 5 2.1. Introduction 5 2.2. Quality aspects 5 2.2.1. Introduction 5 2.2.2. Active substance 5 2.2.3. Finished medicinal product 7 2.2.4

2013 European Medicines Agency - EPARs

18. Donepezil or memantine improved cognitive functioning in moderate-to-severe Alzheimer disease. (PubMed)

Donepezil or memantine improved cognitive functioning in moderate-to-severe Alzheimer disease. ACP Journal Club. Donepezil or memantine improved cognitive functioning in moderate-to-severe Alzheimer disease. - PubMed - NCBI Warning: The NCBI web site requires JavaScript to function. Search database Search term Search Result Filters Format Summary Summary (text) Abstract Abstract (text) MEDLINE XML PMID List Apply Choose Destination File Clipboard Collections E-mail Order My Bibliography (...) Citation manager Format Create File 1 selected item: 22711111 Format MeSH and Other Data E-mail Subject Additional text E-mail Add to Clipboard Add to Collections Order articles Add to My Bibliography Generate a file for use with external citation management software. Create File 2012 Jun 19;156(12):JC6-10. doi: 10.7326/0003-4819-156-12-201206190-02010. ACP Journal Club. Donepezil or memantine improved cognitive functioning in moderate-to-severe Alzheimer disease. 1 . 1 St. Vincent's Health Network

2012 Annals of Internal Medicine

20. The effectiveness and cost-effectiveness of donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer?s disease (review of TA111): a systematic review and economic model

The effectiveness and cost-effectiveness of donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer?s disease (review of TA111): a systematic review and economic model The effectiveness and cost-effectiveness of donepezil, galantamine, rivastigmine and memantine for the treatment of Alzheimer's disease (review of TA111): a systematic review and economic model Journals Library An error has occurred in processing the XML document An error occurred retrieving content

2012 NIHR HTA programme