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Latest & greatest articles for measles
The Trip Database is a leading resource to help health professionals find trustworthy answers to their clinical questions. Users can access the latest research evidence and guidance to answer their clinical questions. We have a large collection of systematic reviews, clinical guidelines, regulatory guidance, clinical trials and many other forms of evidence. If you wanted the latest trusted evidence on measles or other clinical topics then use Trip today.
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Serological effects of Edmonston-Zagreb, Schwarz, and AIK-C measles vaccine strains given at ages 4-5 or 8-10 months. 2574304 1990 01 17 1990 01 17 2015 06 16 0140-6736 2 8676 1989 Dec 09 Lancet (London, England) Lancet Serological effects of Edmonston-Zagreb, Schwarz, and AIK-C measles vaccine strains given at ages 4-5 or 8-10 months. 1357-60 To examine the value of vaccinating children against measles at age 4-5 months three groups of children in Togo were randomly assigned to receive high (...) investigations, particularly epidemiological studies, but they already provide evidence that the administration of AIK-C and high-dose Edmonston-Zagreb strains at 4-5 months is at least as effective as vaccination with the standard strains at 8-10 months. Tidjani O O CHU, Lomé, Togo. Grunitsky B B Guérin N N Lévy-Bruhl D D Lecam N N Xuereff C C Tatagan K K eng Clinical Trial Comparative Study Journal Article Randomized Controlled Trial England Lancet 2985213R 0140-6736 0 Antibodies, Viral 0 Measles Vaccine
Trial of high-dose Edmonston-Zagreb measles vaccine in Guinea-Bissau: protective efficacy. 2902263 1988 11 07 1988 11 07 2015 06 16 0140-6736 2 8615 1988 Oct 08 Lancet (London, England) Lancet Trial of high-dose Edmonston-Zagreb measles vaccine in Guinea-Bissau: protective efficacy. 809-11 In a randomised study of 558 children in an urban African community, the protective effect of the Edmonston-Zagreb (EZ) measles vaccine given in a dose of 40,000 plaque forming units from the age of 4 months (...) was compared with the effects of a standard dose (6000 tissue culture infectious units) of Schwarz measles vaccine given from the age of 9 months. During two years of follow-up, all 14 clinical cases of measles occurred in the Schwarz group; 10 of the children contracted measles before vaccination and 4 after measles vaccination. Thus the EZ vaccine provided significant protection against measles both before and after the usual age of vaccination. Among the children who were exposed to measles at home
Trial of high-dose Edmonston-Zagreb measles vaccine in the Gambia: antibody response and side-effects. 2902264 1988 11 07 1988 11 07 2015 06 16 0140-6736 2 8615 1988 Oct 08 Lancet (London, England) Lancet Trial of high-dose Edmonston-Zagreb measles vaccine in the Gambia: antibody response and side-effects. 811-4 In a randomised trial, infants living in a large village in The Gambia were immunised either at 4 months of age with 40,000 plaque forming units (PFU) of the Edmonston-Zagreb (EZ (...) ) measles vaccine or at the usual age of 9 months with 6000 TCID50 of a conventional Schwarz measles vaccine. Measles developed in 2 of 119 children who received the EZ vaccine, in 1 before and in the other after 9 months of age. In the Schwarz group measles developed in 7 of 120 children--in 5 before and in 2 after 9 months of age. Serological responses measured at 5 months after vaccination and at 18 months of age were satisfactory in both groups although in the Schwarz group levels were on average 2
Effects of dose and strain of vaccine on success of measles vaccination of infants aged 4-5 months. 2896828 1988 06 23 1988 06 23 2015 06 16 0140-6736 1 8592 1988 Apr 30 Lancet (London, England) Lancet Effects of dose and strain of vaccine on success of measles vaccination of infants aged 4-5 months. 963-6 Small-scale trials of the Edmonston-Zagreb (E-Z) measles vaccine were undertaken to determine the dose necessary to immunise 4-6-month-old infants. Antibody responses, measured 16 weeks after (...) vaccination, were dose dependent: 40,000 plaque forming units given subcutaneously resulted in positive responses in all infants and higher antibody levels than doses of 20,000 or 10,000 units (10,000 units gave a failure rate of 25%). In further trials the E-Z vaccine was compared with the Schwarz vaccine, both being given in subcutaneous doses of 40,000 plaque forming units. In infants aged 20 weeks the E-Z vaccine produced higher levels of measles antibody and in those aged 18 weeks its superiority
Frequency of true adverse reactions to measles-mumps-rubella vaccine. A double-blind placebo-controlled trial in twins. 2871241 1986 05 23 1986 05 23 2015 11 19 0140-6736 1 8487 1986 Apr 26 Lancet (London, England) Lancet Frequency of true adverse reactions to measles-mumps-rubella vaccine. A double-blind placebo-controlled trial in twins. 939-42 The vast majority of adverse reactions following immunisation of children with live measles-mumps-rubella (MMR) vaccine were shown in a double-blind (...) , placebo-controlled, cross-over study in 581 twin pairs to be only temporally but not causally related to the vaccination. The true frequency of side-effects caused by MMR vaccine, estimated from the discordance rates of individual signs and symptoms between MMR vaccinees and their placebo-injected twins, was between 0.5 and 4.0%. Moreover, respiratory symptoms, nausea, and vomiting were observed more frequently in the placebo-injected group than in the MMR vaccinated group. Peltola H H Heinonen O P OP
Benefits, risks and costs of immunization for measles, mumps and rubella Benefits, risks and costs of immunization for measles, mumps and rubella Benefits, risks and costs of immunization for measles, mumps and rubella White C C, Koplan J P, Orenstein W A Record Status This is a critical abstract of an economic evaluation that meets the criteria for inclusion on NHS EED. Each abstract contains a brief summary of the methods, the results and conclusions followed by a detailed critical assessment (...) on the reliability of the study and the conclusions drawn. Health technology Measles, mumps and rubella (MMR) vaccine. Type of intervention Primary prevention. Economic study type Cost-effectiveness analysis. Study population All infants in the United States. Setting The study was set in the USA. Dates to which data relate Price related to 1983. Modelling Epidemiological cohort model (model of survival and disease). Direct costs Direct costs were to the health service, and the patient. The price information