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Latest & greatest articles for measles
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A report of outbreaks of measles on the southern coast of Iran from 2009 to 2015 28461876 2018 11 13 2008-5842 9 3 2017 Mar Electronic physician Electron Physician A report of outbreaks of measles on the southern coast of Iran from 2009 to 2015. 3997-4002 10.19082/3997 Immunogenicity assessment figures of the measles vaccine is approximately 90%, and decreases over time. Therefore, the immunity level of measles vaccine is variable which can result in outbreaks of measles in a population (...) . The aim of current study was to report the outbreaks of measles in Hormozgan province from 2009 to 2015. This cross-sectional study was carried out in Hormozgan Province on the southern coast of Iran. The documented data of all cases suspected of measles are included in this study. We used a checklist including gender, age, area, place of residence, contact history, and vaccination status to extract required data. Data was analyzed using IBM SPSS statistics software version 21.0. Eight hundred fifty
Public-health impact of accelerated measles control in the WHO African Region 2000-03. BACKGROUND: In 2000, the WHO African Region adopted a plan to accelerate efforts to lower measles mortality with the goal of decreasing the number of measles deaths to near zero. By June, 2003, 19 African countries had completed measles supplemental immunisation activities (SIA) in children aged 9 months to 14 years as part of a comprehensive measles-control strategy. We assessed the public-health impact (...) of these control measures by use of available surveillance data. METHODS: We calculated percentage decline in reported measles cases during 1-2 years after SIA, compared with 6 years before SIA. On the basis of data from 13 of the 19 countries, we assumed that the percentage decline in measles deaths equalled that in measles cases. We also examined data on routine and SIA measles vaccine coverage, measles case-based surveillance, and suspected measles outbreaks. FINDINGS: Between 2000 and June, 2003, 82.1
Measles-Rubella Bulletin - Vol 11 Issue 1 WHO IRIS: Measles-Rubella Bulletin - Vol 11 Issue 1 Browse Related links Files in This Item: File Description Size Format 2.58 MB Adobe PDF Title: Measles-Rubella Bulletin - Vol 11 Issue 1 Authors: Issue Date: Jan-2017 Publisher: Manila : WHO Regional Office for the Western Pacific Language: English Description: 10 p. Subject: Context: statistics and numerical data URI: ISSN: 1814 3601 Appears in Collections: Items in WHO IRIS are protected by copyright
A Measles Outbreak in an Underimmunized Amish Community in Ohio. BACKGROUND: Although measles was eliminated in the United States in 2000, importations of the virus continue to cause outbreaks. We describe the epidemiologic features of an outbreak of measles that originated from two unvaccinated Amish men in whom measles was incubating at the time of their return to the United States from the Philippines and explore the effect of public health responses on limiting the spread of measles (...) . METHODS: We performed descriptive analyses of data on demographic characteristics, clinical and laboratory evaluations, and vaccination coverage. RESULTS: From March 24, 2014, through July 23, 2014, a total of 383 outbreak-related cases of measles were reported in nine counties in Ohio. The median age of case patients was 15 years (range, <1 to 53); a total of 178 of the case patients (46%) were female, and 340 (89%) were unvaccinated. Transmission took place primarily within households (68
Routine vitamin A supplementation for the prevention of blindness due to measles infection in children. BACKGROUND: Reduced vitamin A concentration increases the risk of blindness in children infected with the measles virus. Promoting vitamin A supplementation in children with measles contributes to the control of blindness in children, which is a high priority within the World Health Organization (WHO) VISION 2020 The Right to Sight Program. OBJECTIVES: To assess the efficacy of vitamin (...) A in preventing blindness in children with measles without prior clinical features of vitamin A deficiency. SEARCH METHODS: We searched CENTRAL 2015, Issue 11, MEDLINE (1950 to December week 3, 2015), Embase (1974 to December 2015) and LILACS (1985 to December 2015). SELECTION CRITERIA: Randomised controlled trials (RCTs) assessing the efficacy of vitamin A in preventing blindness in well-nourished children diagnosed with measles but with no prior clinical features of vitamin A deficiency. DATA COLLECTION
Measles in 2016 Measles in 2016 | Clinical Correlations Measles in 2016 July 20, 2016 By Chio Yokose, MD Peer Reviewed On March 13, 2013, a young traveler returned home from London to our neighboring borough of Brooklyn, NY. Among this individual’s possessions was an active measles infection, one which subsequently led to one of the largest outbreaks of measles in the United States since 1996 [ ]. The individual was an intentionally unvaccinated 17-year-old member of the Orthodox Jewish (...) community in Brooklyn. A total of 58 cases were eventually identified, and all of them were in the Brooklyn Orthodox Jewish community. Of those cases, one child developed viral pneumonia and two pregnant [ ]. Outbreaks of measles continue to occur throughout the United States, despite the fact that the elimination of the indigenous circulation of the measles [ ]. Since then, the US has seen an average of 60 cases of measles per year until 2013, when the incidence nearly tripled to 175 due to 9 major
Association Between Vaccine Refusal and Vaccine-Preventable Diseases in the United States: A Review of Measles and Pertussis. IMPORTANCE: Parents hesitant to vaccinate their children may delay routine immunizations or seek exemptions from state vaccine mandates. Recent outbreaks of vaccine-preventable diseases in the United States have drawn attention to this phenomenon. Improved understanding of the association between vaccine refusal and the epidemiology of these diseases is needed. OBJECTIVE (...) : To review the published literature to evaluate the association between vaccine delay, refusal, or exemption and the epidemiology of measles and pertussis, 2 vaccine-preventable diseases with recent US outbreaks. EVIDENCE REVIEW: Search of PubMed through November 30, 2015, for reports of US measles outbreaks that have occurred since measles was declared eliminated in the United States (after January 1, 2000), endemic and epidemic pertussis since the lowest point in US pertussis incidence (after January 1
Progress towards measles elimination in Nepal, 2007– 2014 = Progrès réalisés en vue d’éliminer la rougeole au Népal, 2007-2014 WHO IRIS: Progress towards measles elimination in Nepal, 2007– 2014 = Progrès réalisés en vue d’éliminer la rougeole au Népal, 2007-2014 Browse Related links Files in This Item: File Description Size Format 638.16 kB Adobe PDF Title: Progress towards measles elimination in Nepal, 2007– 2014 = Progrès réalisés en vue d’éliminer la rougeole au Népal, 2007-2014 Authors
Sixth Hands-on Training on Molecular Laboratory Diagnosis of Measles and Rubella, Hong Kong SAR (China), 29 February to 4 March 2016 : report WHO IRIS: Sixth Hands-on Training on Molecular Laboratory Diagnosis of Measles and Rubella, Hong Kong SAR (China), 29 February to 4 March 2016 : report Browse Related links Files in This Item: File Description Size Format 1.54 MB Adobe PDF Title: Sixth Hands-on Training on Molecular Laboratory Diagnosis of Measles and Rubella, Hong Kong SAR (China), 29
Application of the World Health Organization Programmatic Assessment Tool for Risk of Measles Virus Transmission-Lessons Learned from a Measles Outbreak in Senegal WHO IRIS: Application of the World Health Organization Programmatic Assessment Tool for Risk of Measles Virus Transmission-Lessons Learned from a Measles Outbreak in Senegal Browse Related links Files in This Item: No electronic version is available yet. Title: Application of the World Health Organization Programmatic Assessment Tool (...) for Risk of Measles Virus Transmission-Lessons Learned from a Measles Outbreak in Senegal Authors: Issue Date: 11-Jun-2015 Language: English Abstract: The World Health Organization (WHO) African Region set a goal for regional measles elimination by 2020; however, regional measles incidence was 125/1,000,000 in 2012. To support elimination efforts, the WHO and U.S. Centers for Disease Control and Prevention developed a tool to assess performance of measles control activities and identify high-risk areas
Costs of Contact Tracing Activities Aimed at Reducing the Transmission of Measles in Canada Costs of Contact Tracing Activities Aimed at Reducing the Transmission of Measles in Canada | CADTH.ca Find the information you need Costs of Contact Tracing Activities Aimed at Reducing the Transmission of Measles in Canada Costs of Contact Tracing Activities Aimed at Reducing the Transmission of Measles in Canada Published on: June 1, 2015 Project Number: CP0010 Product Line: Result type: Report (...) Background and Context Measles is a highly communicable infectious disease that is spread through droplets from the nose or throat. Vaccination programs have eliminated indigenous measles in Canada; however, outbreaks continue to occur through importations. Recent outbreaks in Canada and the US have highlighted the importance of immunization for the containment of outbreaks. Contact tracing has been implemented to mitigate the spread of measles by identifying susceptible contacts for treatment
Costs of Contact Tracing Activities Aimed at Reducing the Transmission of Measles in Canada Canadian Agency for Drugs and Technologies in Health Agence canadienne des médicaments et des technologies de la santé Supporting Informed Decisions HTA Costs of Contact Tracing Activities Aimed at Reducing the Transmission of Measles in Canada May 2015 Cite as: Budden A, Lee KM, Lam P. Costs of Contact Tracing Activities Aimed at Reducing the Transmission of Measles in Canada [Internet]. Ottawa: CADTH (...) – May 2015 Costs of Contact Tracing Activities Aimed at Reducing the Transmission of Measles in Canada i TABLE OF CONTENTS ABBREVIATIONS ii EXECUTIVE SUMMARY iii 1. BACKGROUND 1 2. CONTEXT AND POLICY ISSUES 2 3. RESEARCH OBJECTIVE 2 4. METHODS 2 4.1 Literature Search 2 4.2 Overview of the Evidence 3 4.1.1 Appraisal 4 4.1.2 Summary 5 5. ECONOMIC EVALUATION 6 5.1 Methods 6 5.1.1 Type of Economic Evaluation 6 5.1.2 Target Population 6 5.1.3 Perspective 6 5.1.4 Scenarios and Data Sources 6 5.1.5 Model
Public Health Interventions to Reduce the Secondary Spread of Measles Canadian Agency for Drugs and Technologies in Health Agence canadienne des médicaments et des technologies de la santé Supporting Informed Decisions Rapid Response Report: Systematic Review Public Health Interventions to Reduce the Secondary Spread of Measles CADTH May 2015Cite as: Foerster V, Perras C, Spry C, Weeks L. Public health interventions to reduce the secondary spread of measles [Internet]. Ottawa: CADTH; 2015 May (...) . (CADTH rapid response report: systematic review). [cited YYYY-MM-DD]. Available from: https://www.cadth.ca/public-health-interventions-reduce-secondary- spread-measles Disclaimer: This report is a review of existing public literature, studies, materials, and other information and documentation (collectively the “source documentation”) that are available to CADTH. The accuracy of the contents of the source documentation on which this report is based is not warranted, assured, or represented in any way
A Randomized, Controlled Trial of an Aerosolized Vaccine against Measles. 25875257 2015 04 16 2015 04 28 2016 11 22 1533-4406 372 16 2015 Apr 16 The New England journal of medicine N. Engl. J. Med. A randomized, controlled trial of an aerosolized vaccine against measles. 1519-29 10.1056/NEJMoa1407417 Aerosolized vaccine can be used as a needle-free method of immunization against measles, a disease that remains a major cause of illness and death. Data on the immunogenicity of aerosolized vaccine (...) against measles in children are inconsistent. We conducted an open-label noninferiority trial involving children 9.0 to 11.9 months of age in India who were eligible to receive a first dose of measles vaccine. Children were randomly assigned to receive a single dose of vaccine by means of either aerosol inhalation or a subcutaneous injection. The primary end points were seropositivity for antibodies against measles and adverse events 91 days after vaccination. The noninferiority margin was 5
Zinc supplementation for the treatment of measles in children. BACKGROUND: Measles is still an important cause of childhood morbidity and mortality globally, despite increasing vaccine coverage. Zinc plays a significant role in the maintenance of normal immunological functions, therefore supplements given to zinc-deficient children will increase the availability of zinc and could reduce measles-related morbidity and mortality. OBJECTIVES: To assess the effects of zinc supplementation (...) in reducing morbidity and mortality in children with measles. SEARCH METHODS: We searched CENTRAL (2014, Issue 5), MEDLINE (1946 to June week 3, 2014), EMBASE (1974 to June 2014), CINAHL (1981 to June 2014), LILACS (1982 to June 2014), Web of Science (1985 to June 2014) and BIOSIS Previews (1985 to June 2014). We also searched ClinicalTrials.gov and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) to identify unpublished and ongoing studies. SELECTION CRITERIA
Safety of measles-containing vaccines in 1-year-old children 25560438 2015 02 03 2015 03 26 2015 02 03 1098-4275 135 2 2015 Feb Pediatrics Pediatrics Safety of measles-containing vaccines in 1-year-old children. e321-9 10.1542/peds.2014-1822 All measles-containing vaccines are associated with several types of adverse events, including seizure, fever, and immune thrombocytopenia purpura (ITP). Because the measles-mumps-rubella-varicella (MMRV) vaccine compared with the separate (...) measles-mumps-rubella (MMR) and varicella (MMR + V) vaccine increases a toddler's risk for febrile seizures, we investigated whether MMRV is riskier than MMR + V and whether either vaccine elevates the risk for additional safety outcomes. Study children were aged 12 to 23 months in the Vaccine Safety Datalink from 2000 to 2012. Nine study outcomes were investigated: 7 main outcomes (anaphylaxis, ITP, ataxia, arthritis, meningitis/encephalitis, acute disseminated encephalomyelitis, and Kawasaki disease), seizure
Measly protection: passive immunization for measles, past and present http://www.evidentlycochrane.net/wp-content/uploads/2014/04/ Search and hit Go By April 11, 2014 // Mother (to District Visitor). “Lumme Miss, there ain’t no danger of infection. Them children wot’s got the measles is at the ‘ead of the bed, and them wot aint is at the foot.” Wood engraving by S. Wood, 1915. : Wellcome Library, London. When I was about seven, I spent a year going through every infectious disease that children (...) could get in those days: whooping cough, rubella, mumps, chickenpox and measles. With measles, you got sore eyes, a hacking cough, a high fever and a rash that covered you all over. At the time, bed rest in a darkened room was compulsory. My mother left the house to do some quick shopping while I was lying abed, but her timing was poor: a thunderstorm was brewing, and while I lay alone with the curtains closed, the chimney was struck by lightning, the room was shaken by a loud explosion and I
Live vaccine against measles, mumps, and rubella and the risk of hospital admissions for nontargeted infections. IMPORTANCE: In low-income countries, live measles vaccine reduces mortality from causes other than measles infection. Such nonspecific effects of vaccines might also be important for the health of children in high-income settings. OBJECTIVE: To examine whether the live vaccine against measles, mumps, and rubella (MMR) is associated with lower rates of hospital admissions (...) for infections among children in Denmark. DESIGN, SETTING, AND PARTICIPANTS: Population-based cohort study of Danish children born 1997-2006 and followed up from ages 11 months to 2 years (last follow-up, August 31, 2008). Nationwide Danish registers provided data on vaccinations and hospital admissions. The recommended vaccination schedule was inactivated vaccine against diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae type b (DTaP-IPV-Hib) administered at ages 3, 5, and 12 months and MMR
Protection against varicella with two doses of combined measles-mumps-rubella-varicella vaccine versus one dose of monovalent varicella vaccine: a multicentre, observer-blind, randomised, controlled trial. BACKGROUND: Rates of varicella have decreased substantially in countries implementing routine varicella vaccination. Immunisation is possible with monovalent varicella vaccine or a combined measles-mumps-rubella-varicella vaccine (MMRV). We assessed protection against varicella in naive (...) children administered one dose of varicella vaccine or two doses of MMRV. METHODS: This study was done in ten European countries with endemic varicella. Healthy children aged 12-22 months were randomised (3:3:1 ratio, by computer-generated randomisation list, with block size seven) to receive 42 days apart (1) two doses of MMRV (MMRV group), or (2) MMR at dose one and monovalent varicella vaccine at dose two (MMR+V group), or (3) two doses of MMR (MMR group; control). Participants and their parents